Multivariate outbreak detection
On-line monitoring is needed to detect outbreaks of diseases like influenza. Surveillance is also needed for other kinds of outbreaks, in the sense of an increasing expected value after a constant period. Information on spatial location or other variables might be available and may be utilized. We adapted a robust method for outbreak detection to a multivariate case. The relation between the times of the onsets of the outbreaks at different locations (or some other variable) was used to determine the sufficient statistic for surveillance. The derived maximum likelihood estimator of the outbreak regression was semi-parametric in the sense that the baseline and the slope were non-parametric while the distribution belonged to the exponential family. The estimator was used in a generalized likelihood ratio surveillance method. The method was evaluated with respect to robustness and efficiency in a simulation study and applied to spatial data for detection of influenza outbreaks in Sweden.
|Date of creation:||17 Sep 2010|
|Date of revision:|
|Publication status:||Forthcoming as Schiöler, Linus and Marianne Frisén, 'Multivariate outbreak detection' in Journal of Applied Statistics, 2011.|
|Contact details of provider:|| Postal: Statistical Research Unit, University of Gothenburg, Box 640, SE 40530 GÖTEBORG|
Web page: http://www.statistics.gu.se/
References listed on IDEAS
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- Höhle, Michael & Paul, Michaela, 2008. "Count data regression charts for the monitoring of surveillance time series," Computational Statistics & Data Analysis, Elsevier, vol. 52(9), pages 4357-4368, May.
- Frisén, Marianne & Andersson, Eva & Schiöler, Linus, 2009.
"Evaluation of multivariate surveillance,"
2009:1, Statistical Research Unit, Department of Economics, School of Business, Economics and Law, University of Gothenburg.
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- Frisén, Marianne & Andersson, Eva & Schiöler, Linus, 2007. "Robust outbreak surveillance of epidemics in Sweden," Research Reports 2007:12, Statistical Research Unit, Department of Economics, School of Business, Economics and Law, University of Gothenburg.
- Martin Kulldorff, 2001. "Prospective time periodic geographical disease surveillance using a scan statistic," Journal of the Royal Statistical Society Series A, Royal Statistical Society, vol. 164(1), pages 61-72.
- Andrew Lawson & Allan Clark & Carmen Vidal Rodeiro, 2004. "Developments in General and Syndromic Surveillance for Small Area Health Data," Journal of Applied Statistics, Taylor & Francis Journals, vol. 31(8), pages 951-966.
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