IDEAS home Printed from https://ideas.repec.org/p/hal/journl/hal-03188146.html
   My bibliography  Save this paper

Costs and Outcomes of 1-year post-discharge care trajectories of patients admitted with infection due to antibiotic-resistant bacteria

Author

Listed:
  • Mehdi Touat

    (CESP - Centre de recherche en épidémiologie et santé des populations - UVSQ - Université de Versailles Saint-Quentin-en-Yvelines - AP-HP - Assistance publique - Hôpitaux de Paris (AP-HP) - Hôpital Paul Brousse - INSERM - Institut National de la Santé et de la Recherche Médicale - Université Paris-Saclay, EMAE - Epidémiologie et modélisation de la résistance aux antimicrobiens - Epidemiology and modelling of bacterial escape to antimicrobials - IP - Institut Pasteur [Paris] - INSERM - Institut National de la Santé et de la Recherche Médicale)

  • Christian Brun-Buisson

    (CESP - Centre de recherche en épidémiologie et santé des populations - UVSQ - Université de Versailles Saint-Quentin-en-Yvelines - AP-HP - Assistance publique - Hôpitaux de Paris (AP-HP) - Hôpital Paul Brousse - INSERM - Institut National de la Santé et de la Recherche Médicale - Université Paris-Saclay, EMAE - Epidémiologie et modélisation de la résistance aux antimicrobiens - Epidemiology and modelling of bacterial escape to antimicrobials - IP - Institut Pasteur [Paris] - INSERM - Institut National de la Santé et de la Recherche Médicale)

  • Marion Opatowski

    (CESP - Centre de recherche en épidémiologie et santé des populations - UVSQ - Université de Versailles Saint-Quentin-en-Yvelines - AP-HP - Assistance publique - Hôpitaux de Paris (AP-HP) - Hôpital Paul Brousse - INSERM - Institut National de la Santé et de la Recherche Médicale - Université Paris-Saclay, EMAE - Epidémiologie et modélisation de la résistance aux antimicrobiens - Epidemiology and modelling of bacterial escape to antimicrobials - IP - Institut Pasteur [Paris] - INSERM - Institut National de la Santé et de la Recherche Médicale)

  • Jérôme Salomon

    (CESP - Centre de recherche en épidémiologie et santé des populations - UVSQ - Université de Versailles Saint-Quentin-en-Yvelines - AP-HP - Assistance publique - Hôpitaux de Paris (AP-HP) - Hôpital Paul Brousse - INSERM - Institut National de la Santé et de la Recherche Médicale - Université Paris-Saclay, Hôpital Raymond Poincaré [AP-HP], EMAE - Epidémiologie et modélisation de la résistance aux antimicrobiens - Epidemiology and modelling of bacterial escape to antimicrobials - IP - Institut Pasteur [Paris] - INSERM - Institut National de la Santé et de la Recherche Médicale)

  • Didier Guillemot

    (CESP - Centre de recherche en épidémiologie et santé des populations - UVSQ - Université de Versailles Saint-Quentin-en-Yvelines - AP-HP - Assistance publique - Hôpitaux de Paris (AP-HP) - Hôpital Paul Brousse - INSERM - Institut National de la Santé et de la Recherche Médicale - Université Paris-Saclay, Hôpital Raymond Poincaré [AP-HP], EMAE - Epidémiologie et modélisation de la résistance aux antimicrobiens - Epidemiology and modelling of bacterial escape to antimicrobials - IP - Institut Pasteur [Paris] - INSERM - Institut National de la Santé et de la Recherche Médicale)

  • Philippe Tuppin

    (CNAMTS - Caisse Nationale d'Assurance Maladie des Travailleurs salariés - Ministère de l'économie et des finances)

  • Grégoire de Lagasnerie

    (CNAMTS - Caisse Nationale d'Assurance Maladie des Travailleurs salariés - Ministère de l'économie et des finances)

  • Laurence Watier

    (CESP - Centre de recherche en épidémiologie et santé des populations - UVSQ - Université de Versailles Saint-Quentin-en-Yvelines - AP-HP - Assistance publique - Hôpitaux de Paris (AP-HP) - Hôpital Paul Brousse - INSERM - Institut National de la Santé et de la Recherche Médicale - Université Paris-Saclay, Hôpital Raymond Poincaré [AP-HP], EMAE - Epidémiologie et modélisation de la résistance aux antimicrobiens - Epidemiology and modelling of bacterial escape to antimicrobials - IP - Institut Pasteur [Paris] - INSERM - Institut National de la Santé et de la Recherche Médicale)

Abstract

Background: The impact of antibiotic resistance (AMR) on initial hospital management has been extensively studied but its consequences after hospital discharge remain largely unknown. We aimed to analyze hospital care trajectories, cumulative length of hospital stays (c-LOS) and associated costs of care over a 1-year period after hospitalization with incident AMR infection. Method: All incident bacterial infection-related hospitalizations occurring from January 1, 2015, to December 31, 2015 and recorded in the French national health data information system were extracted. Bacterial resistance ICD-10 codes determined six infection status. Inpatient and outpatient care consumption and associated costs were studied. The impact of resistance on c-LOS was estimated using a Poisson regression. A sequence analysis through optimal matching method was conducted to identify hospital trajectories along with an extrapolation. Finding: Of the 73,244 patients selected, 15.9% had AMR infection, thus providing 58,286 incident AMR infections after extrapolation. c-LOS was significantly longer for infections with resistant bacteria, reaching 20.4 days and 2.9 additional days IC95%[2.6; 3.2] for skin and soft tissue infections. An estimated 29,793 (51.1%) patients had hospital readmission within the following year, for a total cost of €675 million. Five post-discharge trajectories were identified: Post-hospitalization mainly at home (68.4% of patients); Transition to home from rehabilitation care (12.3%); Early death (

Suggested Citation

  • Mehdi Touat & Christian Brun-Buisson & Marion Opatowski & Jérôme Salomon & Didier Guillemot & Philippe Tuppin & Grégoire de Lagasnerie & Laurence Watier, 2021. "Costs and Outcomes of 1-year post-discharge care trajectories of patients admitted with infection due to antibiotic-resistant bacteria," Post-Print hal-03188146, HAL.
    • Handle: RePEc:hal:journl:hal-03188146
    DOI: 10.1016/j.jinf.2021.02.001
    Note: View the original document on HAL open archive server: https://hal.science/hal-03188146
    as

    Download full text from publisher

    File URL: https://hal.science/hal-03188146/document
    Download Restriction: no
    File URL: https://libkey.io/10.1016/j.jinf.2021.02.001?utm_source=ideas
    LibKey link: if access is restricted and if your library uses this service, LibKey will redirect you to where you can use your library subscription to access this item
    ---><---

    References listed on IDEAS

    as
    1. Gabadinho, Alexis & Ritschard, Gilbert & Müller, Nicolas S & Studer, Matthias, 2011. "Analyzing and Visualizing State Sequences in R with TraMineR," Journal of Statistical Software, Foundation for Open Access Statistics, vol. 40(i04).
    Full references (including those not matched with items on IDEAS)

    Citations

    Citations are extracted by the CitEc Project, subscribe to its RSS feed for this item.
    as


    Cited by:

    1. Torrini, Irene & Lucifora, Claudio & Russo, Antonio Giampiero, 2023. "The long-term effects of hospitalization on health care expenditures: An empirical analysis for the young-old population in Lombardy," Health Policy, Elsevier, vol. 132(C).

    Most related items

    These are the items that most often cite the same works as this one and are cited by the same works as this one.
    1. Marcel Raab & Emanuela Struffolino, 2020. "The Heterogeneity of Partnership Trajectories to Childlessness in Germany," European Journal of Population, Springer;European Association for Population Studies, vol. 36(1), pages 53-70, March.
    2. Ekaterina Mitrofanova & Alyona Artamonova, 2016. "The perspectives of family policy in Russia amid increasing cohabitation," European Journal of Government and Economics, Europa Grande, vol. 5(1), pages 47-63, June.
    3. Baccar, Mariem & Raynal, Hélène & Sekhar, Muddu & Bergez, Jacques-Eric & Willaume, Magali & Casel, Pierre & Giriraj, P. & Murthy, Sanjeeva & Ruiz, Laurent, 2023. "Dynamics of crop category choices reveal strategies and tactics used by smallholder farmers in India to cope with unreliable water availability," Agricultural Systems, Elsevier, vol. 211(C).
    4. Joanne S. Muller & Nicole Hiekel & Aart C. Liefbroer, 2020. "The Long-Term Costs of Family Trajectories: Women’s Later-Life Employment and Earnings Across Europe," Demography, Springer;Population Association of America (PAA), vol. 57(3), pages 1007-1034, June.
    5. repec:jss:jstsof:40:i04 is not listed on IDEAS
    6. Zachary Van Winkle & Anette Fasang, 2021. "The complexity of employment and family life courses across 20th century Europe: More evidence for larger cross-national differences but little change across 1916‒1966 birth cohorts," Demographic Research, Max Planck Institute for Demographic Research, Rostock, Germany, vol. 44(32), pages 775-810.
    7. Moehring, Katja & Weiland, Andreas & Reifenscheid, Maximiliane & Naumann, Elias & Wenz, Alexander & Rettig, Tobias & Krieger, Ulrich & Fikel, Marina & Cornesse, Carina & Blom, Annelies G., 2021. "Inequality in employment trajectories and their socio-economic consequences during the early phase of the COVID-19 pandemic in Germany," SocArXiv m95df, Center for Open Science.
    8. Babette Bühler & Katja Möhring & Andreas P. Weiland, 2022. "Assessing dissimilarity of employment history information from survey and administrative data using sequence analysis techniques," Quality & Quantity: International Journal of Methodology, Springer, vol. 56(6), pages 4747-4774, December.
    9. Gainbi Park & Zengwang Xu, 2022. "The constituent components and local indicator variables of social vulnerability index," Natural Hazards: Journal of the International Society for the Prevention and Mitigation of Natural Hazards, Springer;International Society for the Prevention and Mitigation of Natural Hazards, vol. 110(1), pages 95-120, January.
    10. Marc A. Scott & Kaushik Mohan & Jacques‐Antoine Gauthier, 2020. "Model‐based clustering and analysis of life history data," Journal of the Royal Statistical Society Series A, Royal Statistical Society, vol. 183(3), pages 1231-1251, June.
    11. Zwiers, Merle & Kleinhans, Reinout & van Ham, Maarten, 2015. "Divided Cities: Increasing Socio-Spatial Polarization within Large Cities in the Netherlands," IZA Discussion Papers 8882, Institute of Labor Economics (IZA).
    12. Devillanova, Carlo & Raitano, Michele & Struffolino, Emanuela, 2019. "Longitudinal employment trajectories and health in middle life: Insights from linked administrative and survey data," EconStor Open Access Articles and Book Chapters, ZBW - Leibniz Information Centre for Economics, pages 1375-1412.
    13. Marcel Raab & Anette Fasang & Aleksi Karhula & Jani Erola, 2014. "Sibling Similarity in Family Formation," Demography, Springer;Population Association of America (PAA), vol. 51(6), pages 2127-2154, December.
    14. Kleinepier, Tom & van Ham, Maarten, 2018. "The Temporal Dynamics of Neighborhood Disadvantage in Childhood and Subsequent Problem Behavior in Adolescence," IZA Discussion Papers 11397, Institute of Labor Economics (IZA).
    15. Michaël Boissonneault, 2021. "Period measures of life course complexity," Demographic Research, Max Planck Institute for Demographic Research, Rostock, Germany, vol. 44(47), pages 1133-1148.
    16. Daniel Ciganda, 2015. "Unstable work histories and fertility in France," Demographic Research, Max Planck Institute for Demographic Research, Rostock, Germany, vol. 32(28), pages 843-876.
    17. Lisa Toczek & Hans Bosma & Richard Peter, 2022. "Early retirement intentions: the impact of employment biographies, work stress and health among a baby-boomer generation," European Journal of Ageing, Springer, vol. 19(4), pages 1479-1491, December.
    18. Valentina Rivera & Francisca Castro, 2021. "Between Social Protests and a Global Pandemic: Working Transitions under the Economic Effects of COVID-19," Social Sciences, MDPI, vol. 10(4), pages 1-21, April.
    19. Ewa Jarosz, 2023. "Does ageing make life simpler? The dynamics, covariates, and implications of complexity of time-use patterns in late adulthood," Quality & Quantity: International Journal of Methodology, Springer, vol. 57(5), pages 4153-4170, October.
    20. Thomas, Llewellyn D.W. & Autio, Erkko & Gann, David M., 2022. "Processes of ecosystem emergence," Technovation, Elsevier, vol. 115(C).
    21. Karen van Hedel & Heta Moustgaard & Mikko Myrskylä & Pekka Martikainen, 2021. "Work-family typologies and mental health among women in early working ages," MPIDR Working Papers WP-2021-015, Max Planck Institute for Demographic Research, Rostock, Germany.

    Corrections

    All material on this site has been provided by the respective publishers and authors. You can help correct errors and omissions. When requesting a correction, please mention this item's handle: RePEc:hal:journl:hal-03188146. See general information about how to correct material in RePEc.

    If you have authored this item and are not yet registered with RePEc, we encourage you to do it here. This allows to link your profile to this item. It also allows you to accept potential citations to this item that we are uncertain about.

    If CitEc recognized a bibliographic reference but did not link an item in RePEc to it, you can help with this form .

    If you know of missing items citing this one, you can help us creating those links by adding the relevant references in the same way as above, for each refering item. If you are a registered author of this item, you may also want to check the "citations" tab in your RePEc Author Service profile, as there may be some citations waiting for confirmation.

    For technical questions regarding this item, or to correct its authors, title, abstract, bibliographic or download information, contact: CCSD (email available below). General contact details of provider: https://hal.archives-ouvertes.fr/ .

    Please note that corrections may take a couple of weeks to filter through the various RePEc services.

    IDEAS is a RePEc service. RePEc uses bibliographic data supplied by the respective publishers.