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rKnowledge: The Spatial Diffusion and Adoption of rDNA Methods

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  • Maryann P. Feldman
  • Dieter F. Kogler
  • David L. Rigby

Abstract

Feldman M. P., Kogler D. F. and Rigby D. L. rKnowledge: the spatial diffusion and adoption of rDNA methods, Regional Studies . The 1980 patent granted to Stanley Cohen and Herbert Boyer for their development of rDNA technology played a critical role in the establishment of the modern biotechnology industry. From the birth of this general-purpose technology in the San Francisco Bay area, rDNA-related knowledge diffused across sectors and regions of the US economy. Patent data are used here to track the geography and timing of rDNA technology adoption in US metropolitan areas. Using event history and fixed effects conditional logit models, it is shown how the diffusion of rDNA techniques was influenced by cognitive, geographical and social proximity.

Suggested Citation

  • Maryann P. Feldman & Dieter F. Kogler & David L. Rigby, 2015. "rKnowledge: The Spatial Diffusion and Adoption of rDNA Methods," Regional Studies, Taylor & Francis Journals, vol. 49(5), pages 798-817, May.
    • Handle: RePEc:taf:regstd:v:49:y:2015:i:5:p:798-817
    DOI: 10.1080/00343404.2014.980799
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    References listed on IDEAS

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    1. Stefano Breschi & Francesco Lissoni, 2004. "Knowledge networks from patent data: Methodological issues and research targets," KITeS Working Papers 150, KITeS, Centre for Knowledge, Internationalization and Technology Studies, Universita' Bocconi, Milano, Italy, revised Jan 2004.
    2. Bronwyn H. Hall & Grid Thoma & Salvatore Torrisi, 2006. "The market value of patents and R&D: Evidence from European firms," KITeS Working Papers 186, KITeS, Centre for Knowledge, Internationalization and Technology Studies, Universita' Bocconi, Milano, Italy, revised Nov 2006.
    3. Ricardo Hausmann & Bailey Klinger, 2007. "The Structure of the Product Space and the Evolution of Comparative Advantage," Growth Lab Working Papers 10, Harvard's Growth Lab.
    4. Lipsey, Richard G. & Carlaw, Kenneth I. & Bekar, Clifford T., 2005. "Economic Transformations: General Purpose Technologies and Long-Term Economic Growth," OUP Catalogue, Oxford University Press, number 9780199290895.
    5. David S. Abrams & Ufuk Akcigit & Jillian Grennan, 2013. "Patent Value and Citations: Creative Destruction or Strategic Disruption?," NBER Working Papers 19647, National Bureau of Economic Research, Inc.
    6. Bronwyn H. Hall & Adam B. Jaffe & Manuel Trajtenberg, 2001. "The NBER Patent Citation Data File: Lessons, Insights and Methodological Tools," NBER Working Papers 8498, National Bureau of Economic Research, Inc.
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