IDEAS home Printed from https://ideas.repec.org/a/spr/stabio/v10y2018i1d10.1007_s12561-018-9214-7.html
   My bibliography  Save this article

Valuing Sets of Potential Transplants in a Kidney Paired Donation Network

Author

Listed:
  • Mathieu Bray

    (University of Michigan)

  • Wen Wang

    (University of Michigan)

  • Peter X.-K. Song

    (University of Michigan)

  • John D. Kalbfleisch

    (University of Michigan
    University of Michigan)

Abstract

In kidney paired donation (KPD), incompatible donor–candidate pairs and non-directed (also known as altruistic) donors are pooled together with the aim of maximizing the total utility of transplants realized via donor exchanges. We consider a setting in which disjoint sets of potential transplants are selected at regular intervals, with fallback options available within each proposed set in the case of individual donor, candidate, or match failure. We develop methods for calculating the expected utility for such sets under a realistic probability model for the KPD. Exact expected utility calculations for these sets are compared to estimates based on Monte Carlo samples of the underlying network. Models and methods are extended to include transplant candidates who join KPD with more than one incompatible donor. Microsimulations demonstrate the superiority of accounting for failure probability and fallback options, as well as candidates joining with additional donors, in terms of realized transplants and waiting time for candidates.

Suggested Citation

  • Mathieu Bray & Wen Wang & Peter X.-K. Song & John D. Kalbfleisch, 2018. "Valuing Sets of Potential Transplants in a Kidney Paired Donation Network," Statistics in Biosciences, Springer;International Chinese Statistical Association, vol. 10(1), pages 255-279, April.
    • Handle: RePEc:spr:stabio:v:10:y:2018:i:1:d:10.1007_s12561-018-9214-7
    DOI: 10.1007/s12561-018-9214-7
    as

    Download full text from publisher

    File URL: http://link.springer.com/10.1007/s12561-018-9214-7
    File Function: Abstract
    Download Restriction: Access to the full text of the articles in this series is restricted.
    File URL: https://libkey.io/10.1007/s12561-018-9214-7?utm_source=ideas
    LibKey link: if access is restricted and if your library uses this service, LibKey will redirect you to where you can use your library subscription to access this item
    ---><---

    As the access to this document is restricted, you may want to search for a different version of it.

    References listed on IDEAS

    as
    1. Roth, Alvin E. & Sonmez, Tayfun & Unver, Utku & Delmonico, Francis & Saidman, Susan L., 2014. "Utilizing List Exchange and Non-directed Donation through “Chain” Paired Kidney Donations," MPRA Paper 58246, University Library of Munich, Germany.
    2. Alvin E. Roth & Tayfun Sönmez & M. Utku Ünver, 2004. "Kidney Exchange," The Quarterly Journal of Economics, President and Fellows of Harvard College, vol. 119(2), pages 457-488.
    3. Tayfun Sönmez & Alvin E. Roth & M. Utku Ünver, 2007. "Efficient Kidney Exchange: Coincidence of Wants in Markets with Compatibility-Based Preferences," American Economic Review, American Economic Association, vol. 97(3), pages 828-851, June.
    4. Roth, Alvin E. & Sonmez, Tayfun & Utku Unver, M., 2005. "Pairwise kidney exchange," Journal of Economic Theory, Elsevier, vol. 125(2), pages 151-188, December.
    5. Rees, Michael Kenneth & Kopke, Jonathan E. & Pelletier, Ronald P. & Segev, Dorry L. & Rutter, Matthew E. & Fabrega, Alfredo J. & Rogers, Jeffrey David & Pankewycz, Oleh G. & Hiller, Janet & Roth, Alvi, 2009. "A Nonsimultaneous, Extended, Altruistic-Donor Chain," Scholarly Articles 29408291, Harvard University Department of Economics.
    Full references (including those not matched with items on IDEAS)

    Most related items

    These are the items that most often cite the same works as this one and are cited by the same works as this one.
    1. Sönmez, Tayfun & Ünver, M. Utku & Yılmaz, Özgür, 2018. "How (not) to integrate blood subtyping technology to kidney exchange," Journal of Economic Theory, Elsevier, vol. 176(C), pages 193-231.
    2. Nicolò, Antonio & Rodríguez-Álvarez, Carmelo, 2017. "Age-based preferences in paired kidney exchange," Games and Economic Behavior, Elsevier, vol. 102(C), pages 508-524.
    3. Tayfun Sönmez & M Utku Ünver, 2017. "Market design for living-donor organ exchanges: an economic policy perspective," Oxford Review of Economic Policy, Oxford University Press and Oxford Review of Economic Policy Limited, vol. 33(4), pages 676-704.
    4. Ross Anderson & Itai Ashlagi & David Gamarnik & Michael Rees & Alvin E. Roth & Tayfun Sönmez & M. Utku Ünver, 2015. "Kidney Exchange and the Alliance for Paired Donation: Operations Research Changes the Way Kidneys Are Transplanted," Interfaces, INFORMS, vol. 45(1), pages 26-42, February.
    5. Alvin E. Roth, 2010. "Marketplace Institutions Related to the Timing of Transactions," NBER Working Papers 16556, National Bureau of Economic Research, Inc.
    6. Alvin E. Roth, 2012. "Marketplace Institutions Related to the Timing of Transactions: Reply to Priest," Journal of Labor Economics, University of Chicago Press, vol. 30(2), pages 479-494.
    7. Alvin E. Roth, 2009. "What Have We Learned from Market Design?," Innovation Policy and the Economy, University of Chicago Press, vol. 9(1), pages 79-112.
    8. Andersson, Tommy & Kratz, Jörgen, 2016. "Kidney Exchange over the Blood Group Barrier," Working Papers 2016:11, Lund University, Department of Economics, revised 29 Nov 2017.
    9. YIlmaz, Özgür, 2011. "Kidney exchange: An egalitarian mechanism," Journal of Economic Theory, Elsevier, vol. 146(2), pages 592-618, March.
    10. Yılmaz, Özgür, 2014. "Kidney exchange: Further utilization of donors via listed exchange," Journal of Mathematical Economics, Elsevier, vol. 51(C), pages 178-186.
    11. Committee, Nobel Prize, 2012. "Alvin E. Roth and Lloyd S. Shapley: Stable allocations and the practice of market design," Nobel Prize in Economics documents 2012-1, Nobel Prize Committee.
    12. Kessler, Judd B. & Roth, Alvin E., 2014. "Loopholes undermine donation: An experiment motivated by an organ donation priority loophole in Israel," Journal of Public Economics, Elsevier, vol. 114(C), pages 19-28.
    13. Murat Kurt & Mark S. Roberts & Andrew J. Schaefer & M. Utku Ünver, 2011. "Valuing Prearranged Paired Kidney Exchanges: A Stochastic Game Approach," Boston College Working Papers in Economics 785, Boston College Department of Economics, revised 14 Oct 2011.
    14. Alvin E. Roth, 2007. "Repugnance as a Constraint on Markets," Journal of Economic Perspectives, American Economic Association, vol. 21(3), pages 37-58, Summer.
    15. Itai Ashlagi & Alvin E. Roth, 2011. "Individual Rationality and Participation in Large Scale, Multi-Hospital Kidney Exchange," NBER Working Papers 16720, National Bureau of Economic Research, Inc.
    16. Constantino, Miguel & Klimentova, Xenia & Viana, Ana & Rais, Abdur, 2013. "New insights on integer-programming models for the kidney exchange problem," European Journal of Operational Research, Elsevier, vol. 231(1), pages 57-68.
    17. Scott Duke Kominers & Alexander Teytelboym & Vincent P Crawford, 2017. "An invitation to market design," Oxford Review of Economic Policy, Oxford University Press and Oxford Review of Economic Policy Limited, vol. 33(4), pages 541-571.
    18. Ivan Balbuzanov & Maciej H. Kotowski, 2019. "Endowments, Exclusion, and Exchange," Econometrica, Econometric Society, vol. 87(5), pages 1663-1692, September.
    19. Ashlagi, Itai & Fischer, Felix & Kash, Ian A. & Procaccia, Ariel D., 2015. "Mix and match: A strategyproof mechanism for multi-hospital kidney exchange," Games and Economic Behavior, Elsevier, vol. 91(C), pages 284-296.
    20. Alvin Roth, 2008. "Deferred acceptance algorithms: history, theory, practice, and open questions," International Journal of Game Theory, Springer;Game Theory Society, vol. 36(3), pages 537-569, March.

    Corrections

    All material on this site has been provided by the respective publishers and authors. You can help correct errors and omissions. When requesting a correction, please mention this item's handle: RePEc:spr:stabio:v:10:y:2018:i:1:d:10.1007_s12561-018-9214-7. See general information about how to correct material in RePEc.

    If you have authored this item and are not yet registered with RePEc, we encourage you to do it here. This allows to link your profile to this item. It also allows you to accept potential citations to this item that we are uncertain about.

    If CitEc recognized a bibliographic reference but did not link an item in RePEc to it, you can help with this form .

    If you know of missing items citing this one, you can help us creating those links by adding the relevant references in the same way as above, for each refering item. If you are a registered author of this item, you may also want to check the "citations" tab in your RePEc Author Service profile, as there may be some citations waiting for confirmation.

    For technical questions regarding this item, or to correct its authors, title, abstract, bibliographic or download information, contact: Sonal Shukla or Springer Nature Abstracting and Indexing (email available below). General contact details of provider: http://www.springer.com .

    Please note that corrections may take a couple of weeks to filter through the various RePEc services.

    IDEAS is a RePEc service. RePEc uses bibliographic data supplied by the respective publishers.