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Innovation ecosystems: a comparison between university spin-off firms and innovative start-ups. Evidence from Italy

Author

Listed:
  • Michele Modina

    (University of Molise)

  • Francesco Capalbo

    (University of Molise)

  • Marco Sorrentino

    (Pegaso Telematic University)

  • Gabriele Ianiro

    (University of Molise)

  • Muhammad Fayaz Khan

    (University of Molise)

Abstract

To date, research on ecosystems has separated them into three categories, namely business, innovation, and entrepreneurial; however, few studies have analyzed their outputs in terms of innovative business creation. Innovative business creation can differ between university spin-offs and innovative start-ups, and as far as we know, a comparison of the performance of each with respect to growth in sales has not yet been provided. This paper contributes to providing theoretical and empirical insights into the performance of innovation ecosystems, university spin-offs (USOs) and innovative start-ups (ISs) in Italy and the effectiveness of ecosystem-level interactions. Through the lens of the innovation system, the paper examines two datasets of 305 university spin-offs and 1494 innovative start-ups in Italy, including firm-specific, university-specific, industry-specific, time-specific and ecosystem-specific data. The empirical research takes place via panel data regression that compares the performances of university spin-offs and innovative start-ups, measured by growth in sales. It emerges that sales growth is positively related to ISs performance, while innovativeness and network building does not leverage growth for all companies in the same way. Not surprisingly, innovative start-ups in High R&D sectors show higher rates of growth in sales than USOs and are more closely connected with the regional innovation ecosystem. Thus, to enhance growth for other early-stage innovative companies, especially if coming from academia or sectors with lower R&D investments, it is important to invest in R&D activities, in building relationships in the commercial world, and in particular in enhancing relationships regarding sale activities, including staff exchange, specific training and ecosystem events regarding innovation ecosystems, intertwining national, regional and sectorial systems.

Suggested Citation

  • Michele Modina & Francesco Capalbo & Marco Sorrentino & Gabriele Ianiro & Muhammad Fayaz Khan, 2024. "Innovation ecosystems: a comparison between university spin-off firms and innovative start-ups. Evidence from Italy," International Entrepreneurship and Management Journal, Springer, vol. 20(2), pages 575-605, June.
    • Handle: RePEc:spr:intemj:v:20:y:2024:i:2:d:10.1007_s11365-023-00857-2
    DOI: 10.1007/s11365-023-00857-2
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    1. Ross Brown & Colin Mason, 2017. "Looking inside the spiky bits: a critical review and conceptualisation of entrepreneurial ecosystems," Small Business Economics, Springer, vol. 49(1), pages 11-30, June.
    2. Etzkowitz, Henry & Leydesdorff, Loet, 2000. "The dynamics of innovation: from National Systems and "Mode 2" to a Triple Helix of university-industry-government relations," Research Policy, Elsevier, vol. 29(2), pages 109-123, February.
    3. Walter, Achim & Auer, Michael & Ritter, Thomas, 2006. "The impact of network capabilities and entrepreneurial orientation on university spin-off performance," Journal of Business Venturing, Elsevier, vol. 21(4), pages 541-567, July.
    4. Scaringella, Laurent & Radziwon, Agnieszka, 2018. "Innovation, entrepreneurial, knowledge, and business ecosystems: Old wine in new bottles?," Technological Forecasting and Social Change, Elsevier, vol. 136(C), pages 59-87.
    5. Paul E. Bierly & Fariborz Damanpour & Michael D. Santoro, 2009. "The Application of External Knowledge: Organizational Conditions for Exploration and Exploitation," Journal of Management Studies, Wiley Blackwell, vol. 46(3), pages 481-509, May.
    6. Pinaki Nandan Pattnaik & Satyendra C. Pandey, 2016. "Revisiting University Spinoffs: Conceptual Advancements and Theoretical Underpinnings," International Journal of Innovation and Technology Management (IJITM), World Scientific Publishing Co. Pte. Ltd., vol. 13(01), pages 1-13, February.
    7. María Jesús Rodríguez-Gulías & David Rodeiro-Pazos & Sara Fernández-López & Christian Corsi & Antonio Prencipe, 2018. "The role of venture capitalist to enhance the growth of Spanish and Italian university spin-offs," International Entrepreneurship and Management Journal, Springer, vol. 14(4), pages 1111-1130, December.
    8. Elizabeth Garnsey & Erik Stam & Paul Heffernan, 2006. "New Firm Growth: Exploring Processes and Paths," Industry and Innovation, Taylor & Francis Journals, vol. 13(1), pages 1-20.
    9. Nuria Calvo & David Rodeiro & Isabel Soares, 2013. "Are USOs more supported to compete than spin-offs not linked to universities? A dynamic overview and proposal of model of USOs support," International Journal of Innovation and Learning, Inderscience Enterprises Ltd, vol. 14(3/4), pages 271-288.
    10. Gerrit de Wit & Haibo Zhou, 2009. "Determinants and dimensions of firm growth," Scales Research Reports H200903, EIM Business and Policy Research.
    11. Michele Meoli & Silvio Vismara, 2016. "University support and the creation of technology and non-technology academic spin-offs," Small Business Economics, Springer, vol. 47(2), pages 345-362, August.
    12. Coad, Alex & Rao, Rekha, 2008. "Innovation and firm growth in high-tech sectors: A quantile regression approach," Research Policy, Elsevier, vol. 37(4), pages 633-648, May.
    13. David Huffman & John M. Quigley, 2002. "The role of the university in attracting high tech entrepreneurship: A Silicon Valley tale," The Annals of Regional Science, Springer;Western Regional Science Association, vol. 36(3), pages 403-419.
    14. Toole, Andrew A. & Czarnitzki, Dirk, 2007. "Biomedical academic entrepreneurship through the SBIR program," Journal of Economic Behavior & Organization, Elsevier, vol. 63(4), pages 716-738, August.
    15. Tommy Clausen & Einar Rasmussen, 2013. "Parallel business models and the innovativeness of research-based spin-off ventures," The Journal of Technology Transfer, Springer, vol. 38(6), pages 836-849, December.
    16. Rothaermel, Frank T. & Thursby, Marie, 2005. "Incubator firm failure or graduation?: The role of university linkages," Research Policy, Elsevier, vol. 34(7), pages 1076-1090, September.
    17. Manlio Giudice & Maria Della Peruta & Vincenzo Maggioni, 2013. "Collective Knowledge and Organizational Routines within Academic Communities of Practice: an Empirical Research on Science–Entrepreneurs," Journal of the Knowledge Economy, Springer;Portland International Center for Management of Engineering and Technology (PICMET), vol. 4(3), pages 260-278, September.
    18. Yan Yan & Jiancheng Guan, 2019. "Entrepreneurial ecosystem, entrepreneurial rate and innovation: the moderating role of internet attention," International Entrepreneurship and Management Journal, Springer, vol. 15(2), pages 625-650, June.
    19. Zoltan J. Acs & Erik Stam & David B. Audretsch & Allan O’Connor, 2017. "The lineages of the entrepreneurial ecosystem approach," Small Business Economics, Springer, vol. 49(1), pages 1-10, June.
    20. Nicoletta Buratti & Giorgia Profumo & Luca Persico, 2021. "The impact of market orientation on university spin-off business performance," Journal of International Entrepreneurship, Springer, vol. 19(1), pages 104-129, March.
    21. John-Christopher Spender & Vincenzo Corvello & Michele Grimaldi & Pierluigi Rippa, 2017. "Startups and open innovation: a review of the literature," European Journal of Innovation Management, Emerald Group Publishing Limited, vol. 20(1), pages 4-30, January.
    22. Erik Stam, 2015. "Entrepreneurial Ecosystems and Regional Policy: A Sympathetic Critique," European Planning Studies, Taylor & Francis Journals, vol. 23(9), pages 1759-1769, September.
    23. Colombelli, Alessandra & Krafft, Jackie & Vivarelli, Marco, 2016. "To Be Born Is Not Enough: The Key Role of Innovative Startups," IZA Discussion Papers 9733, Institute of Labor Economics (IZA).
    24. Ben Spigel, 2017. "The Relational Organization of Entrepreneurial Ecosystems," Entrepreneurship Theory and Practice, , vol. 41(1), pages 49-72, January.
    25. Yanxia Li & Bo Zou & Feng Guo & Jinyu Guo, 2022. "Academic entrepreneurs’ effectuation logic, role innovation, and academic entrepreneurship performance: an empirical study," International Entrepreneurship and Management Journal, Springer, vol. 18(1), pages 49-72, March.
    26. Colombo, Massimo G. & Delmastro, Marco, 2002. "How effective are technology incubators?: Evidence from Italy," Research Policy, Elsevier, vol. 31(7), pages 1103-1122, September.
    27. van Burg, E. & Gilsing, V.A. & Reymen, I.M.M.J. & Romme, A.G.L., 2008. "Creating university spin-offs : A science-based design perspective," Other publications TiSEM ed13609d-fde4-43dc-ba8a-d, Tilburg University, School of Economics and Management.
    28. Riccardo Fini & Kun Fu & Marius Tuft Mathisen & Einar Rasmussen & Mike Wright, 2017. "Institutional determinants of university spin-off quantity and quality: a longitudinal, multilevel, cross-country study," Small Business Economics, Springer, vol. 48(2), pages 361-391, February.
    29. Angelo Cavallo & Antonio Ghezzi & Raffaello Balocco, 2019. "Entrepreneurial ecosystem research: present debates and future directions," International Entrepreneurship and Management Journal, Springer, vol. 15(4), pages 1291-1321, December.
    30. Maribel Guerrero & Francisco Liñán & F. Rafael Cáceres-Carrasco, 2021. "The influence of ecosystems on the entrepreneurship process: a comparison across developed and developing economies," Small Business Economics, Springer, vol. 57(4), pages 1733-1759, December.
    31. Paul Swamidass, 2013. "University startups as a commercialization alternative: lessons from three contrasting case studies," The Journal of Technology Transfer, Springer, vol. 38(6), pages 788-808, December.
    32. O'Shea, Rory P. & Allen, Thomas J. & Chevalier, Arnaud & Roche, Frank, 2005. "Entrepreneurial orientation, technology transfer and spinoff performance of U.S. universities," Research Policy, Elsevier, vol. 34(7), pages 994-1009, September.
    33. Ensley, Michael D. & Hmieleski, Keith M., 2005. "A comparative study of new venture top management team composition, dynamics and performance between university-based and independent start-ups," Research Policy, Elsevier, vol. 34(7), pages 1091-1105, September.
    34. Junfu Zhang, 2009. "The performance of university spin-offs: an exploratory analysis using venture capital data," The Journal of Technology Transfer, Springer, vol. 34(3), pages 255-285, June.
    35. Audretsch, David & Colombelli, Alessandra & Grilli, Luca & Minola, Tommaso & Rasmussen, Einar, 2020. "Innovative start-ups and policy initiatives," Research Policy, Elsevier, vol. 49(10).
    36. Barbara Del Bosco & Alice Mazzucchelli & Roberto Chierici & Angelo Di Gregorio, 2021. "Innovative startup creation: the effect of local factors and demographic characteristics of entrepreneurs," International Entrepreneurship and Management Journal, Springer, vol. 17(1), pages 145-164, March.
    37. Carlos Díaz-Santamaría & Jacques Bulchand-Gidumal, 2021. "Econometric Estimation of the Factors That Influence Startup Success," Sustainability, MDPI, vol. 13(4), pages 1-14, February.
    38. Konstantinos Pitsakis & Vangelis Souitaris & Nicos Nicolaou, 2015. "The Peripheral Halo Effect: Do Academic Spinoffs Influence Universities' Research Income?," Journal of Management Studies, Wiley Blackwell, vol. 52(3), pages 321-353, May.
    39. Marius Tuft Mathisen & Einar Rasmussen, 2019. "The development, growth, and performance of university spin-offs: a critical review," The Journal of Technology Transfer, Springer, vol. 44(6), pages 1891-1938, December.
    40. Robert A. Lowe & Arvids A. Ziedonis, 2006. "Overoptimism and the Performance of Entrepreneurial Firms," Management Science, INFORMS, vol. 52(2), pages 173-186, February.
    41. Elisa Salvador, 2011. "How effective are research spin-off firms in Italy?," Revue d'économie industrielle, De Boeck Université, vol. 0(1), pages 99-122.
    42. Grimaldi, Rosa & Kenney, Martin & Siegel, Donald S. & Wright, Mike, 2011. "30 years after Bayh-Dole: Reassessing academic entrepreneurship," Research Policy, Elsevier, vol. 40(8), pages 1045-1057, October.
    43. Wennberg, Karl & Wiklund, Johan & Wright, Mike, 2011. "The effectiveness of university knowledge spillovers: Performance differences between university spinoffs and corporate spinoffs," Research Policy, Elsevier, vol. 40(8), pages 1128-1143, October.
    44. Granstrand, Ove & Holgersson, Marcus, 2020. "Innovation ecosystems: A conceptual review and a new definition," Technovation, Elsevier, vol. 90.
    45. Henry Etzkowitz, 2002. "Incubation of incubators: innovation as a triple helix of university-industry-government networks," Science and Public Policy, Oxford University Press, vol. 29(2), pages 115-128, April.
    46. Rappert, Brian & Webster, Andrew & Charles, David, 1999. "Making sense of diversity and reluctance: academic-industrial relations and intellectual property," Research Policy, Elsevier, vol. 28(8), pages 873-890, November.
    47. Frank T. Rothaermel & Shanti D. Agung & Lin Jiang, 2007. "University entrepreneurship: a taxonomy of the literature," Industrial and Corporate Change, Oxford University Press and the Associazione ICC, vol. 16(4), pages 691-791, August.
    48. Rasmussen, Einar & Mosey, Simon & Wright, Mike, 2014. "The influence of university departments on the evolution of entrepreneurial competencies in spin-off ventures," Research Policy, Elsevier, vol. 43(1), pages 92-106.
    49. Oh, Deog-Seong & Phillips, Fred & Park, Sehee & Lee, Eunghyun, 2016. "Innovation ecosystems: A critical examination," Technovation, Elsevier, vol. 54(C), pages 1-6.
    50. Nora Hesse & Rolf Sternberg, 2017. "Alternative growth patterns of university spin-offs: why so many remain small?," International Entrepreneurship and Management Journal, Springer, vol. 13(3), pages 953-984, September.
    51. Johan Wiklund & Holger Patzelt & Dean Shepherd, 2009. "Building an integrative model of small business growth," Small Business Economics, Springer, vol. 32(4), pages 351-374, April.
    52. Charles W. Wessner, 2005. "Entrepreneurship and the Innovation Ecosystem Policy Lessons from the United States," International Studies in Entrepreneurship, in: Local Heroes in the Global Village, chapter 0, pages 67-89, Springer.
    53. Nanette S. Levinson, 2010. "Innovation in cross-national alliance ecosystems," International Journal of Entrepreneurship and Innovation Management, Inderscience Enterprises Ltd, vol. 11(3), pages 258-263.
    54. Witte, Patrick & Slack, Brian & Keesman, Maarten & Jugie, Jeanne-Hélène & Wiegmans, Bart, 2018. "Facilitating start-ups in port-city innovation ecosystems: A case study of Montreal and Rotterdam," Journal of Transport Geography, Elsevier, vol. 71(C), pages 224-234.
    55. Lockett, Andy & Siegel, Donald & Wright, Mike & Ensley, Michael D., 2005. "The creation of spin-off firms at public research institutions: Managerial and policy implications," Research Policy, Elsevier, vol. 34(7), pages 981-993, September.
    56. Franco Malerba & Maureen McKelvey, 2020. "Knowledge-intensive innovative entrepreneurship integrating Schumpeter, evolutionary economics, and innovation systems," Small Business Economics, Springer, vol. 54(2), pages 503-522, February.
    57. Fahimeh Khatami & Veronica Scuotto & Norris Krueger & Valter Cantino, 2022. "The influence of the entrepreneurial ecosystem model on sustainable innovation from a macro-level lens," International Entrepreneurship and Management Journal, Springer, vol. 18(4), pages 1419-1451, December.
    58. Wennekers, Sander & Thurik, Roy, 1999. "Linking Entrepreneurship and Economic Growth," Small Business Economics, Springer, vol. 13(1), pages 27-55, August.
    59. Gary J. Castrogiovanni, 2018. "Guest editor’s introduction: so what is entrepreneurship research?," International Entrepreneurship and Management Journal, Springer, vol. 14(3), pages 509-511, September.
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