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Physical measures of physical functioning as prognostic factors in predicting outcomes for neck and thoracic pain: Protocol for a systematic review

Author

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  • Rabea Begum
  • Alison Rushton
  • Alaa El Chamaa
  • David Walton
  • Paul Parikh

Abstract

Background: Spinal pain is prevalent and burdensome worldwide. A large proportion of patients with neck and thoracic pain experience chronic symptoms, which can significantly impact their physical functioning. Therefore, it is important to understand factors predicting outcome to inform effective examination and treatment. Knowledge of physical measures of physical functioning as prognostic factors can enhance patient-centered care and aid decision-making. The evidence regarding physical outcome measures as prognostic factors for neck and thoracic pain is unclear. The objective of this study is to summarize the evidence for physical outcome measures of physical functioning as prognostic factors in predicting outcomes in people with neck and thoracic pain. Methods and analysis: This systematic review follows Cochrane guidelines and aligns with the Preferred Reporting Items for Systematic Review and Meta-Analysis Protocols (PRISMA-P). Included studies will be prospective longitudinal cohort studies in which physical measures of physical functioning are explored as prognostic factors for adults with neck and thoracic pain. A comprehensive search will be performed in key databases (MEDLINE, EMBASE, CINAHL, Scopus, and Web of Science) and the grey literature, with hand searches of key journals, and the reference lists of included studies. Two reviewers will independently perform study selection, data extraction, risk of bias assessment (QUIPS, Quality in Prognostic Studies tool), and quality assessment (Grading of Recommendations Assessment, Development, and Evaluation). Implications: This systematic review will identify physical measures of physical functioning prognostic factors for neck and thoracic pain populations. Findings will inform researchers about gaps in existing evidence, and clinicians about factors to aid their clinical decisions and to enhance the overall quality of care for individuals with neck and thoracic pain.

Suggested Citation

  • Rabea Begum & Alison Rushton & Alaa El Chamaa & David Walton & Paul Parikh, 2025. "Physical measures of physical functioning as prognostic factors in predicting outcomes for neck and thoracic pain: Protocol for a systematic review," PLOS ONE, Public Library of Science, vol. 20(1), pages 1-16, January.
    • Handle: RePEc:plo:pone00:0316827
    DOI: 10.1371/journal.pone.0316827
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    References listed on IDEAS

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    1. Rameeza Rashed & Katie Kowalski & David Walton & Afieh Niazigharemakhe & Alison Rushton, 2023. "Physical measures of physical functioning as prognostic factors to predict outcomes in low back pain: Protocol for a systematic review," PLOS ONE, Public Library of Science, vol. 18(12), pages 1-11, December.
    2. David Moher & Alessandro Liberati & Jennifer Tetzlaff & Douglas G Altman & The PRISMA Group, 2009. "Preferred Reporting Items for Systematic Reviews and Meta-Analyses: The PRISMA Statement," PLOS Medicine, Public Library of Science, vol. 6(7), pages 1-6, July.
    3. Karel G M Moons & Joris A H de Groot & Walter Bouwmeester & Yvonne Vergouwe & Susan Mallett & Douglas G Altman & Johannes B Reitsma & Gary S Collins, 2014. "Critical Appraisal and Data Extraction for Systematic Reviews of Prediction Modelling Studies: The CHARMS Checklist," PLOS Medicine, Public Library of Science, vol. 11(10), pages 1-12, October.
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