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Determinants of COVID-19 vaccine acceptance and hesitancy among adolescents and youths aged 10-35 years in sub-Saharan African countries: A systematic review and meta-analysis

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  • Allan Mayaba Mwiinde
  • Patrick Kaonga
  • Choolwe Jacobs
  • Joseph Mumba Zulu
  • Isaac Fwemba

Abstract

The COVID-19 pandemic has overwhelmed health systems, especially in sub-Saharan African countries. Vaccination is one of the easily accessible interventions that can help reduce the burden on the health system. However, vaccination coverage remains low in sub-Saharan African countries. The determinants of vaccine acceptance and hesitancy among adolescents and youths remain unknown. Therefore, this study explored the pooled prevalence and determinants of COVID-19 vaccine acceptance and hesitancy among adolescents and youths in sub-Saharan African Countries. A systematic literature search of Scopus, PubMed Central, PubMed, Embase, African Journal Online, Research 4 Life, Embase, and Google Scholar was performed from 6th May to 31st December 2023, using developed keywords with a focus on sub-Saharan African countries. Twenty-three (N = 23) studies were finally selected for analysis. The pooled prevalence of vaccine acceptance among adolescents and youths was 38.7% (n = 23). The subgroup analysis of the pooled prevalence of acceptance among adolescents was 36.1% (n = 36.1) while youths were 42% (n = 10). At the region level, West Africa had 42.2% (n = 13), East Africa had 39.8% (n = 6), Central Africa had 33% (n = 1), and Southern Africa had 24.2% (n = 3). The determinants of vaccine acceptance were the desire for self-immunity (AOR = 1.97, 95%, CI, 1.083.47, I2 = 94.15%, p

Suggested Citation

  • Allan Mayaba Mwiinde & Patrick Kaonga & Choolwe Jacobs & Joseph Mumba Zulu & Isaac Fwemba, 2024. "Determinants of COVID-19 vaccine acceptance and hesitancy among adolescents and youths aged 10-35 years in sub-Saharan African countries: A systematic review and meta-analysis," PLOS ONE, Public Library of Science, vol. 19(10), pages 1-21, October.
    • Handle: RePEc:plo:pone00:0310827
    DOI: 10.1371/journal.pone.0310827
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    References listed on IDEAS

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    1. Jonathan A.C. Sterne & Roger M. Harbord, 2004. "Funnel plots in meta-analysis," Stata Journal, StataCorp LLC, vol. 4(2), pages 127-141, June.
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