IDEAS home Printed from https://ideas.repec.org/a/plo/pone00/0282789.html
   My bibliography  Save this article

In-hospital stress and patient outcomes: A systematic review and meta-analysis

Author

Listed:
  • Daniel M Ford
  • Luke Budworth
  • Rebecca Lawton
  • Elizabeth A Teale
  • Daryl B O’Connor

Abstract

Background: Hospital inpatients are exposed to high levels of stress during hospitalisation that may increase susceptibility to major adverse health events post-hospitalisation (known as post-hospital syndrome). However, the existing evidence base has not been reviewed and the magnitude of this relationship remains unknown. Therefore, the aim of the current systematic review and meta-analysis was to: 1) synthesise existing evidence and to determine the strength of the relationship between in-hospital stress and patient outcomes, and 2) determine if this relationship differs between (i) in-hospital vs post-hospital outcomes, and (ii) subjective vs objective outcome measures. Methods: A systematic search of MEDLINE, EMBASE, PsychINFO, CINAHL, and Web of Science from inception to February 2023 was conducted. Included studies reported a measure of perceived and appraised stress while in hospital, and at least one patient outcome. A random-effects model was generated to pool correlations (Pearson’s r), followed by sub-group and sensitivity analyses. The study protocol was preregistered on PROSPERO (CRD42021237017). Results: A total of 10 studies, comprising 16 effects and 1,832 patients, satisfied the eligibility criteria and were included. A small-to-medium association was found: as in-hospital stress increased, patient outcomes deteriorated (r = 0.19; 95% CI: 0.12–0.26; I2 = 63.6; p

Suggested Citation

  • Daniel M Ford & Luke Budworth & Rebecca Lawton & Elizabeth A Teale & Daryl B O’Connor, 2023. "In-hospital stress and patient outcomes: A systematic review and meta-analysis," PLOS ONE, Public Library of Science, vol. 18(3), pages 1-17, March.
    • Handle: RePEc:plo:pone00:0282789
    DOI: 10.1371/journal.pone.0282789
    as

    Download full text from publisher

    File URL: https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0282789
    Download Restriction: no
    File URL: https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0282789&type=printable
    Download Restriction: no
    File URL: https://libkey.io/10.1371/journal.pone.0282789?utm_source=ideas
    LibKey link: if access is restricted and if your library uses this service, LibKey will redirect you to where you can use your library subscription to access this item
    ---><---

    References listed on IDEAS

    as
    1. repec:plo:pone00:0091477 is not listed on IDEAS
    2. Sue Duval & Richard Tweedie, 2000. "Trim and Fill: A Simple Funnel-Plot–Based Method of Testing and Adjusting for Publication Bias in Meta-Analysis," Biometrics, The International Biometric Society, vol. 56(2), pages 455-463, June.
    3. David Moher & Alessandro Liberati & Jennifer Tetzlaff & Douglas G Altman & The PRISMA Group, 2009. "Preferred Reporting Items for Systematic Reviews and Meta-Analyses: The PRISMA Statement," PLOS Medicine, Public Library of Science, vol. 6(7), pages 1-6, July.
    4. James Heckman, 2013. "Sample selection bias as a specification error," Applied Econometrics, Russian Presidential Academy of National Economy and Public Administration (RANEPA), vol. 31(3), pages 129-137.
    5. Alejandra Recio‐Saucedo & Chiara Dall'Ora & Antonello Maruotti & Jane Ball & Jim Briggs & Paul Meredith & Oliver C Redfern & Caroline Kovacs & David Prytherch & Gary B Smith & Peter Griffiths, 2018. "What impact does nursing care left undone have on patient outcomes? Review of the literature," Journal of Clinical Nursing, John Wiley & Sons, vol. 27(11-12), pages 2248-2259, June.
    Full references (including those not matched with items on IDEAS)

    Most related items

    These are the items that most often cite the same works as this one and are cited by the same works as this one.
    1. Daniele Zago & Maria Eugênia Andrighetto Canozzi & Júlio Otávio Jardim Barcellos, 2020. "Pregnant beef cow’s nutrition and its effects on postnatal weight and carcass quality of their progeny," PLOS ONE, Public Library of Science, vol. 15(8), pages 1-20, August.
    2. Viktoria Maria Baumeister & Leonie Petra Kuen & Maike Bruckes & Gerhard Schewe, 2021. "The Relationship of Work-Related ICT Use With Well-being, Incorporating the Role of Resources and Demands: A Meta-Analysis," SAGE Open, , vol. 11(4), pages 21582440211, November.
    3. Hyun Kim & Navneet Kaur Baidwan & David Kriebel & Manuel Cifuentes & Sherry Baron, 2018. "Asthma among World Trade Center First Responders: A Qualitative Synthesis and Bias Assessment," IJERPH, MDPI, vol. 15(6), pages 1-14, May.
    4. Ritchwood, Tiarney D. & Ford, Haley & DeCoster, Jamie & Sutton, Marnie & Lochman, John E., 2015. "Risky sexual behavior and substance use among adolescents: A meta-analysis," Children and Youth Services Review, Elsevier, vol. 52(C), pages 74-88.
    5. Christopher Winchester & Kelsey E. Medeiros, 2023. "In Bounds but Out of the Box: A Meta-Analysis Clarifying the Effect of Ethicality on Creativity," Journal of Business Ethics, Springer, vol. 183(3), pages 713-743, March.
    6. Lianjie Liu & Zhuo Shao & Hang Yu & Wei Zhang & Hao Wang & Zubing Mei, 2020. "Is the platelet to lymphocyte ratio a promising biomarker to distinguish acute appendicitis? Evidence from a systematic review with meta-analysis," PLOS ONE, Public Library of Science, vol. 15(5), pages 1-15, May.
    7. Victor Orozco-Olvera & Fuyuan Shen & Lucie Cluver, 2019. "The effectiveness of using entertainment education narratives to promote safer sexual behaviors of youth: A meta-analysis, 1985-2017," PLOS ONE, Public Library of Science, vol. 14(2), pages 1-14, February.
    8. Sara Farag & Catherine Tsang & Philip N Murphy, 2023. "Polyphenol supplementation and executive functioning in overweight and obese adults at risk of cognitive impairment: A systematic review and meta-analysis," PLOS ONE, Public Library of Science, vol. 18(5), pages 1-22, May.
    9. Mohammad Najm Dadam & Le Thanh Hien & Engy M Makram & Lam Vinh Sieu & Ahmad Morad & Nada Khalil & Linh Tran & Abdelrahman M Makram & Nguyen Tien Huy, 2024. "Role of cell-free DNA levels in the diagnosis and prognosis of sepsis and bacteremia: A systematic review and meta-analysis," PLOS ONE, Public Library of Science, vol. 19(8), pages 1-16, August.
    10. Fabrizio Sgolastra & Ambra Petrucci & Marco Severino & Roberto Gatto & Annalisa Monaco, 2013. "Relationship between Periodontitis and Pre-Eclampsia: A Meta-Analysis," PLOS ONE, Public Library of Science, vol. 8(8), pages 1-11, August.
    11. Ioana A Cristea & Robin N Kok & Pim Cuijpers, 2016. "The Effectiveness of Cognitive Bias Modification Interventions for Substance Addictions: A Meta-Analysis," PLOS ONE, Public Library of Science, vol. 11(9), pages 1-19, September.
    12. Je-Young Lee & Minkyung Baek, 2023. "Effects of Gamification on Students’ English Language Proficiency: A Meta-Analysis on Research in South Korea," Sustainability, MDPI, vol. 15(14), pages 1-19, July.
    13. S Bally & J Cottin & M C Gagnieu & J C Lega & C Verstuyft & S Rheims & G Lesca & M Cucherat & Guillaume Grenet, 2022. "Publication bias in pharmacogenetics of adverse reaction to antiseizure drugs: An umbrella review and a meta-epidemiological study," PLOS ONE, Public Library of Science, vol. 17(12), pages 1-14, December.
    14. Alvisa Palese & Jessica Longhini & Matteo Danielis, 2021. "To what extent Unfinished Nursing Care tools coincide with the discrete elements of The Fundamentals of Care Framework? A comparative analysis based on a systematic review," Journal of Clinical Nursing, John Wiley & Sons, vol. 30(1-2), pages 239-265, January.
    15. Martin Polak & Norbert Tanzer & Per Carlbring, 2022. "PROTOCOL: Effects of virtual reality exposure therapy versus in vivo exposure in treating social anxiety disorder in adults: A systematic review and meta‐analysis," Campbell Systematic Reviews, John Wiley & Sons, vol. 18(3), September.
    16. Muthanna Samara & Bruna Da Silva Nascimento & Aiman El-Asam & Sara Hammuda & Nabil Khattab, 2021. "How Can Bullying Victimisation Lead to Lower Academic Achievement? A Systematic Review and Meta-Analysis of the Mediating Role of Cognitive-Motivational Factors," IJERPH, MDPI, vol. 18(5), pages 1-21, February.
    17. Wan Shakira Rodzlan Hasani & Nor Asiah Muhamad & Nur Hasnah Maamor & Tengku Muhammad Hanis & Chen Xin Wee & Muhammad Radzi Abu Hassan & Zulkarnain Abdul Karim & Kamarul Imran Musa, 2023. "Premature mortality and years of potential life lost from cardiovascular diseases: Protocol of a systematic review and meta-analysis," PLOS ONE, Public Library of Science, vol. 18(5), pages 1-11, May.
    18. Xian-Tao Zeng & Wei Luo & Wei Huang & Quan Wang & Yi Guo & Wei-Dong Leng, 2013. "Tooth Loss and Head and Neck Cancer: A Meta-Analysis of Observational Studies," PLOS ONE, Public Library of Science, vol. 8(11), pages 1-8, November.
    19. Zhao-Feng Chen & Lufei Young & Chong Ho Yu & S. Pamela K. Shiao, 2018. "A Meta-Prediction of Methylenetetrahydrofolate-Reductase Polymorphisms and Air Pollution Increased the Risk of Ischemic Heart Diseases Worldwide," IJERPH, MDPI, vol. 15(7), pages 1-16, July.
    20. Chun-Yu Chang & Po-Chen Lin & Yung-Jiun Chien & Chien-Sheng Chen & Meng-Yu Wu, 2020. "Analysis of Chest-Compression Depth and Full Recoil in Two Infant Chest-Compression Techniques Performed by a Single Rescuer: Systematic Review and Meta-Analysis," IJERPH, MDPI, vol. 17(11), pages 1-17, June.

    More about this item

    Statistics

    Access and download statistics

    Corrections

    All material on this site has been provided by the respective publishers and authors. You can help correct errors and omissions. When requesting a correction, please mention this item's handle: RePEc:plo:pone00:0282789. See general information about how to correct material in RePEc.

    If you have authored this item and are not yet registered with RePEc, we encourage you to do it here. This allows to link your profile to this item. It also allows you to accept potential citations to this item that we are uncertain about.

    If CitEc recognized a bibliographic reference but did not link an item in RePEc to it, you can help with this form .

    If you know of missing items citing this one, you can help us creating those links by adding the relevant references in the same way as above, for each refering item. If you are a registered author of this item, you may also want to check the "citations" tab in your RePEc Author Service profile, as there may be some citations waiting for confirmation.

    For technical questions regarding this item, or to correct its authors, title, abstract, bibliographic or download information, contact: plosone (email available below). General contact details of provider: https://journals.plos.org/plosone/ .

    Please note that corrections may take a couple of weeks to filter through the various RePEc services.

    IDEAS is a RePEc service. RePEc uses bibliographic data supplied by the respective publishers.