IDEAS home Printed from https://ideas.repec.org/a/plo/pgph00/0000301.html
   My bibliography  Save this article

Impact of intensified tuberculosis case finding at health facilities on case notifications in Cameroon: A controlled interrupted time series analysis

Author

Listed:
  • Zourriyah Adamou Mana
  • Chrysal Ngouateu Beaudou
  • Kamga Fotue Jean Hilaire
  • Joceline Konso
  • Carole Ndahbove
  • Yvonne Waindim
  • Maurice Ganava
  • Toussaint Malama
  • Christian Matip
  • Paul Meoto
  • Irene Adeline Goupeyou Wandji
  • Mercy Fundoh
  • Cyrille Mbuli
  • Vuchas Comfort
  • Pride Teyim
  • Sandra Alba
  • Jacob Creswell
  • Vincent Mbassa
  • Melissa Sander

Abstract

There is a large gap between the number of people who develop tuberculosis (TB) and those who are diagnosed, treated and notified, with only an estimated 71% of people with TB notified globally in 2019. Implementing better TB case finding strategies is necessary to close this gap. In Cameroon, 1,597 healthcare workers at 725 health facilities were trained and engaged to intensively screen and test people for TB, then follow-up to link people to appropriate care. Primary care centers were linked to TB testing through a locally-tailored specimen referral network. This intervention was implemented across 6 regions of the country, with a population of 16 million people, while the remaining 4 regions in the country, with 7.3 million people, served as a control area. Controlled interrupted time series analyses were used to compare routinely-collected programmatic TB case notification rates in the intervention versus control area for 12 quarters prior to (2016–2018) and for 8 quarters after the start of the intervention (2019–2020). In 2019–2020, a total of 167,508 people were tested for TB at intervention sites, including 52,980 people attending primary care facilities that did not previously provide organized TB services. The number of people tested for TB increased by 45% during the intervention as compared to prior to the intervention. The controlled interrupted time series analyses showed that after two years of the intervention, the all-forms TB case notification rate in the intervention population increased by 9% (ratio of case notification rate ratios = 1.09, 95% CI 1.06 to 1.12), as compared with the counterfactual estimated from pre-intervention trends. This increase was observed even during a negative national impact on case finding from the COVID-19 pandemic. These results support the use of this health-facility based intervention to improve access to TB testing and care in this setting.

Suggested Citation

  • Zourriyah Adamou Mana & Chrysal Ngouateu Beaudou & Kamga Fotue Jean Hilaire & Joceline Konso & Carole Ndahbove & Yvonne Waindim & Maurice Ganava & Toussaint Malama & Christian Matip & Paul Meoto & Ire, 2022. "Impact of intensified tuberculosis case finding at health facilities on case notifications in Cameroon: A controlled interrupted time series analysis," PLOS Global Public Health, Public Library of Science, vol. 2(7), pages 1-17, July.
    • Handle: RePEc:plo:pgph00:0000301
    DOI: 10.1371/journal.pgph.0000301
    as

    Download full text from publisher

    File URL: https://journals.plos.org/globalpublichealth/article?id=10.1371/journal.pgph.0000301
    Download Restriction: no
    File URL: https://journals.plos.org/globalpublichealth/article/file?id=10.1371/journal.pgph.0000301&type=printable
    Download Restriction: no
    File URL: https://libkey.io/10.1371/journal.pgph.0000301?utm_source=ideas
    LibKey link: if access is restricted and if your library uses this service, LibKey will redirect you to where you can use your library subscription to access this item
    ---><---

    References listed on IDEAS

    as
    1. Ariel Linden, 2015. "Conducting interrupted time-series analysis for single- and multiple-group comparisons," Stata Journal, StataCorp LLC, vol. 15(2), pages 480-500, June.
    Full references (including those not matched with items on IDEAS)

    Most related items

    These are the items that most often cite the same works as this one and are cited by the same works as this one.
    1. KAMKOUM, Arnaud Cedric, 2023. "The Federal Reserve’s Response to the Global Financial Crisis and its Effects: An Interrupted Time-Series Analysis of the Impact of its Quantitative Easing Programs," Thesis Commons d7pvg, Center for Open Science.
    2. Drew M. Anderson & David B. Monaghan & Jed Richardson, 2024. "Can the Promise of Free Education Improve College Attainment? Lessons from the Milwaukee Area Technical College Promise," Research in Higher Education, Springer;Association for Institutional Research, vol. 65(8), pages 1747-1770, December.
    3. Samba Diop & Simplice A. Asongu, 2022. "The impact of Covid-19 and Russia-Ukraine war on food prices in fragile countries: misfortunes never come singly," Working Papers 22/055, European Xtramile Centre of African Studies (EXCAS).
    4. Díaz, Juan-José & Sánchez, Alan & Diez-Canseco, Francisco & Jaime Miranda, J. & Popkin, Barry M., 2023. "Employment and wage effects of sugar-sweetened beverage taxes and front-of-package warning label regulations on the food and beverage industry: Evidence from Peru," Food Policy, Elsevier, vol. 115(C).
    5. Meenan, Richard T. & Frank, Lawrence D. & Saelens, Brian E. & Young, Deborah R. & Kuntz, Jennifer L. & Dickerson, John F. & Wali, Behram & Keast, Erin M. & Fortmann, Stephen P., 2022. "Effects of an urban light rail line on health care utilization and cost: A pre-post assessment," Transport Policy, Elsevier, vol. 123(C), pages 112-120.
    6. Elvina Merkaj & Raffaella Santolini, 2021. "National Policies In Response To The Covid-19 Pandemic: The Case Of Friuli-Venezia-Giulia And Umbria," Working Papers 456, Universita' Politecnica delle Marche (I), Dipartimento di Scienze Economiche e Sociali.
    7. Alexander Karaivanov & Dongwoo Kim & Shih En Lu & Hitoshi Shigeoka, 2022. "COVID-19 vaccination mandates and vaccine uptake," Nature Human Behaviour, Nature, vol. 6(12), pages 1615-1624, December.
    8. Sutherland, Alex & Ariel, Barak & Farrar, William & De Anda, Randy, 2017. "Post-experimental follow-ups—Fade-out versus persistence effects: The Rialto police body-worn camera experiment four years on," Journal of Criminal Justice, Elsevier, vol. 53(C), pages 110-116.
    9. Christopher Ksoll & Kristine Bos & Sarah Hughes & Anthony Harris & Arif Mamun, "undated". "Evaluation Design Report for the Benin Power Compact's Electricity Generation Project and Electricity Distribution Project," Mathematica Policy Research Reports 9f8974513ee745aaac3b5c62e, Mathematica Policy Research.
    10. Fiorentini, Gianluca & Bruni, Matteo Lippi & Mammi, Irene, 2022. "The same old medicine but cheaper: The impact of patent expiry on physicians’ prescribing behaviour," Journal of Economic Behavior & Organization, Elsevier, vol. 204(C), pages 37-68.
    11. Zhang, Dingxuan & Sun, Yuying & Duan, Hongbo & Hong, Yongmiao & Wang, Shouyang, 2023. "Speculation or currency? Multi-scale analysis of cryptocurrencies—The case of Bitcoin," International Review of Financial Analysis, Elsevier, vol. 88(C).
    12. Erica Raimondi & Loris Vergolini, 2017. "‘Everyone in School’: The Effects of Compulsory Schooling Age on Drop-out and Completion Rates," FBK-IRVAPP Working Papers 2017-05, Research Institute for the Evaluation of Public Policies (IRVAPP), Bruno Kessler Foundation.
    13. Arnaud Cedric Kamkoum, 2023. "The Federal Reserve's Response to the Global Financial Crisis and Its Long-Term Impact: An Interrupted Time-Series Natural Experimental Analysis," Papers 2305.12318, arXiv.org.
    14. Paraje, Guillermo & Colchero, Arantxa & Wlasiuk, Juan Marcos & Sota, Antonio Martner & Popkin, Barry M., 2021. "The effects of the Chilean food policy package on aggregate employment and real wages," Food Policy, Elsevier, vol. 100(C).
    15. repec:plo:pmed00:1003227 is not listed on IDEAS
    16. Lin Xie & Jiahua Liao & Haiting Chen & Xuefei Yan & Xinyan Hu, 2021. "Is Futurization the Culprit for the Violent Fluctuation in China’s Apple Spot Price?," Agriculture, MDPI, vol. 11(4), pages 1-14, April.
    17. Wang, Daniel & Vasconcelos, Natália Pires de & Poirier, Mathieu JP & Chieffi, Ana & Mônaco, Cauê & Sritharan, Lathika & Van Katwyk, Susan Rogers & Hoffman, Steven J, 2020. "Health technology assessment and judicial deference to priority-setting decisions in healthcare: Quasi-experimental analysis of right-to-health litigation in Brazil," Social Science & Medicine, Elsevier, vol. 265(C).
    18. Henrik Andersson & Kristoffer Jutvik, 2023. "Do asylum‐seekers respond to policy changes? Evidence from the Swedish–Syrian case," Scandinavian Journal of Economics, Wiley Blackwell, vol. 125(1), pages 3-31, January.
    19. Han, Sungil & Riddell, Jordan R., 2024. "A new college campus and crime: Focusing on crime opportunity and gentrification in downtown Orlando, Florida," Journal of Criminal Justice, Elsevier, vol. 95(C).
    20. Nancy M. Wells & Nilda Graciela Cosco & Derek Hales & Muntazar Monsur & Robin C. Moore, 2023. "Gardening in Childcare Centers: A Randomized Controlled Trial Examining the Effects of a Garden Intervention on Physical Activity among Children Aged 3–5 Years in North Carolina," IJERPH, MDPI, vol. 20(11), pages 1-16, May.
    21. Cassandra R. Chambers & Wayne E. Baker, 2020. "Robust Systems of Cooperation in the Presence of Rankings: How Displaying Prosocial Contributions Can Offset the Disruptive Effects of Performance Rankings," Organization Science, INFORMS, vol. 31(2), pages 287-307, March.

    More about this item

    Statistics

    Access and download statistics

    Corrections

    All material on this site has been provided by the respective publishers and authors. You can help correct errors and omissions. When requesting a correction, please mention this item's handle: RePEc:plo:pgph00:0000301. See general information about how to correct material in RePEc.

    If you have authored this item and are not yet registered with RePEc, we encourage you to do it here. This allows to link your profile to this item. It also allows you to accept potential citations to this item that we are uncertain about.

    If CitEc recognized a bibliographic reference but did not link an item in RePEc to it, you can help with this form .

    If you know of missing items citing this one, you can help us creating those links by adding the relevant references in the same way as above, for each refering item. If you are a registered author of this item, you may also want to check the "citations" tab in your RePEc Author Service profile, as there may be some citations waiting for confirmation.

    For technical questions regarding this item, or to correct its authors, title, abstract, bibliographic or download information, contact: globalpubhealth (email available below). General contact details of provider: https://journals.plos.org/globalpublichealth .

    Please note that corrections may take a couple of weeks to filter through the various RePEc services.

    IDEAS is a RePEc service. RePEc uses bibliographic data supplied by the respective publishers.