IDEAS home Printed from https://ideas.repec.org/a/inm/orinte/v36y2006i6p591-607.html
   My bibliography  Save this article

Large-Scale Dispensing for Emergency Response to Bioterrorism and Infectious-Disease Outbreak

Author

Listed:
  • Eva K. Lee

    (Center for Operations Research in Medicine and HealthCare, School of Industrial and Systems Engineering, Georgia Institute of Technology, Atlanta, Georgia 30332-0205)

  • Siddhartha Maheshwary

    (Center for Operations Research in Medicine and HealthCare, School of Industrial and Systems Engineering, Georgia Institute of Technology, Atlanta, Georgia 30332-0205)

  • Jacquelyn Mason

    (Public Health Environmental Readiness Branch, Centers for Disease Control and Prevention, Division of Emergency and Environmental Health Services, Chamblee, Georgia 30341)

  • William Glisson

    (DeKalb County Board of Health, Office of Emergency Preparedness, DeKalb, Georgia 30030)

Abstract

We describe RealOpt © , a simulation and decision-support system for planning large-scale emergency dispensing clinics to respond to biological threats and infectious-disease outbreaks. The system allows public-health administrators to investigate clinic-design and staffing scenarios quickly. The system incorporates efficient optimization technology seamlessly interfaced with a simulation module.The simulation studies we present explore facility-layout and staffing scenarios for an actual anthrax-emergency drill, and we discuss post-event analysis. Using our staff allocation and assignments for the exercise, DeKalb County achieved the highest throughput among all counties that simultaneously conducted the same scale of anthrax drill at various locations. Its labor usage was at or below that of the other counties. The external evaluators commented that DeKalb produced the most efficient floor plan (with no path crossing), the most cost-effective dispensing (lowest labor and throughput value), and the smoothest operations (shortest average wait time, average queue length, and equalized utilization rate). The study proves that even without historical data, the use of our system enables emergency personnel to plan ahead and be able to estimate required labor resources accurately. The exercise also revealed many areas that need attention during the operations planning and design of dispensing centers.A real-time decision-support system is, therefore, viable through careful design of a stand-alone simulator, coupled with powerful and tailored optimization solvers. The system facilitates analysis of “what-if” scenarios, and serves as an invaluable tool for operational planning and dynamic, on-the-fly reconfigurations of large-scale emergency dispensing clinics. It also allows performing “virtual field exercises” on the decision-support system, offering insight into operations flow and bottlenecks when mass dispensing is required for a region with a large population. Working with emergency-response departments, we will perform additional tuning and development of the system to address different biological attacks and infectious-disease outbreaks, and to ensure its practicality and usability.

Suggested Citation

  • Eva K. Lee & Siddhartha Maheshwary & Jacquelyn Mason & William Glisson, 2006. "Large-Scale Dispensing for Emergency Response to Bioterrorism and Infectious-Disease Outbreak," Interfaces, INFORMS, vol. 36(6), pages 591-607, December.
  • Handle: RePEc:inm:orinte:v:36:y:2006:i:6:p:591-607
    DOI: 10.1287/inte.1060.0257
    as

    Download full text from publisher

    File URL: http://dx.doi.org/10.1287/inte.1060.0257
    Download Restriction: no

    File URL: https://libkey.io/10.1287/inte.1060.0257?utm_source=ideas
    LibKey link: if access is restricted and if your library uses this service, LibKey will redirect you to where you can use your library subscription to access this item
    ---><---

    References listed on IDEAS

    as
    1. Yves Dallery & Yannick Frein, 1993. "On Decomposition Methods for Tandem Queueing Networks with Blocking," Operations Research, INFORMS, vol. 41(2), pages 386-399, April.
    2. Stanley B. Gershwin, 1987. "An Efficient Decomposition Method for the Approximate Evaluation of Tandem Queues with Finite Storage Space and Blocking," Operations Research, INFORMS, vol. 35(2), pages 291-305, April.
    3. Nathaniel Hupert & Alvin I. Mushlin & Mark A. Callahan, 2002. "Modeling the Public Health Response to Bioterrorism: Using Discrete Event Simulation to Design Antibiotic Distribution Centers," Medical Decision Making, , vol. 22(1_suppl), pages 17-25, September.
    4. Eglese, R. W., 1990. "Simulated annealing: A tool for operational research," European Journal of Operational Research, Elsevier, vol. 46(3), pages 271-281, June.
    5. Heavey, C. & Papadopoulos, H. T. & Browne, J., 1993. "The throughput rate of multistation unreliable production lines," European Journal of Operational Research, Elsevier, vol. 68(1), pages 69-89, July.
    6. Raymond Gani & Steve Leach, 2001. "Transmission potential of smallpox in contemporary populations," Nature, Nature, vol. 414(6865), pages 748-751, December.
    7. Eva Lee & Siddhartha Maheshwary & Jacquelyn Mason & William Glisson, 2006. "Decision support system for mass dispensing of medications for infectious disease outbreaks and bioterrorist attacks," Annals of Operations Research, Springer, vol. 148(1), pages 25-53, November.
    Full references (including those not matched with items on IDEAS)

    Citations

    Citations are extracted by the CitEc Project, subscribe to its RSS feed for this item.
    as


    Cited by:

    1. Zhang, Yi & Xu, Jiuping & Nekovee, Maziar & Li, Zongmin, 2022. "The impact of official rumor-refutation information on the dynamics of rumor spread," Physica A: Statistical Mechanics and its Applications, Elsevier, vol. 607(C).
    2. Gregory S. Zaric & Dena M. Bravata & Jon-Erik Cleophas Holty & Kathryn M. McDonald & Douglas K. Owens & Margaret L. Brandeau, 2008. "Modeling the Logistics of Response to Anthrax Bioterrorism," Medical Decision Making, , vol. 28(3), pages 332-350, May.
    3. Caunhye, Aakil M. & Li, Mingzhe & Nie, Xiaofeng, 2015. "A location-allocation model for casualty response planning during catastrophic radiological incidents," Socio-Economic Planning Sciences, Elsevier, vol. 50(C), pages 32-44.
    4. Fetter, Gary & Rakes, Terry, 2012. "Incorporating recycling into post-disaster debris disposal," Socio-Economic Planning Sciences, Elsevier, vol. 46(1), pages 14-22.
    5. David Simchi-Levi & Nikolaos Trichakis & Peter Yun Zhang, 2019. "Designing Response Supply Chain Against Bioattacks," Operations Research, INFORMS, vol. 67(5), pages 1246-1268, September.
    6. Desheng Dash Wu & Jia Liu & David L. Olson, 2015. "Simulation Decision System on the Preparation of Emergency Resources Using System Dynamics," Systems Research and Behavioral Science, Wiley Blackwell, vol. 32(6), pages 603-615, November.
    7. Carlo Drago & Matteo Ruggeri, 2019. "Setting research priorities in the field of emergency management: which piece of information are you willing to pay more?," Quality & Quantity: International Journal of Methodology, Springer, vol. 53(4), pages 2103-2115, July.
    8. Zhao, Laijun & Wang, Qin & Cheng, Jingjing & Zhang, Ding & Ma, Ting & Chen, Yucheng & Wang, Jiajia, 2012. "The impact of authorities’ media and rumor dissemination on the evolution of emergency," Physica A: Statistical Mechanics and its Applications, Elsevier, vol. 391(15), pages 3978-3987.
    9. İ. Esra Büyüktahtakın & Robert G. Haight, 2018. "A review of operations research models in invasive species management: state of the art, challenges, and future directions," Annals of Operations Research, Springer, vol. 271(2), pages 357-403, December.
    10. Aakil M. Caunhye & Xiaofeng Nie, 2018. "A Stochastic Programming Model for Casualty Response Planning During Catastrophic Health Events," Transportation Science, INFORMS, vol. 52(2), pages 437-453, March.
    11. Eva K. Lee & Chien-Hung Chen & Ferdinand Pietz & Bernard Benecke, 2009. "Modeling and Optimizing the Public-Health Infrastructure for Emergency Response," Interfaces, INFORMS, vol. 39(5), pages 476-490, October.
    12. Duijzer, Lotty Evertje & van Jaarsveld, Willem & Dekker, Rommert, 2018. "Literature review: The vaccine supply chain," European Journal of Operational Research, Elsevier, vol. 268(1), pages 174-192.
    13. Eva K. Lee & Ferdinand Pietz & Bernard Benecke & Jacquelyn Mason & Greg Burel, 2013. "Advancing Public Health and Medical Preparedness with Operations Research," Interfaces, INFORMS, vol. 43(1), pages 79-98, February.
    14. Dean, Matthew D. & Nair, Suresh K., 2014. "Mass-casualty triage: Distribution of victims to multiple hospitals using the SAVE model," European Journal of Operational Research, Elsevier, vol. 238(1), pages 363-373.
    15. Eva K. Lee & Chien-Hung Chen & Niquelle Brown & Joseph Handy & Alex Desiderio & Ruth Lopez & Brian Davis, 2012. "Designing Guest Flow and Operations Logistics for the Dolphin Tales," Interfaces, INFORMS, vol. 42(5), pages 492-506, October.
    16. Huo, Liang’an & Ma, Chenyang, 2017. "The interaction evolution model of mass incidents with delay in a social network," Physica A: Statistical Mechanics and its Applications, Elsevier, vol. 484(C), pages 440-452.
    17. Yiping Jiang & Yufei Yuan, 2019. "Emergency Logistics in a Large-Scale Disaster Context: Achievements and Challenges," IJERPH, MDPI, vol. 16(5), pages 1-23, March.
    18. Eva K. Lee & Hany Y. Atallah & Michael D. Wright & Eleanor T. Post & Calvin Thomas & Daniel T. Wu & Leon L. Haley, 2015. "Transforming Hospital Emergency Department Workflow and Patient Care," Interfaces, INFORMS, vol. 45(1), pages 58-82, February.
    19. Feng, Keli & Bizimana, Emmanuel & Agu, Deedee D. & Issac, Tana T., 2012. "Optimization and Simulation Modeling of Disaster Relief Supply Chain: A Literature Review," MPRA Paper 58204, University Library of Munich, Germany.

    Most related items

    These are the items that most often cite the same works as this one and are cited by the same works as this one.
    1. Eva Lee & Siddhartha Maheshwary & Jacquelyn Mason & William Glisson, 2006. "Decision support system for mass dispensing of medications for infectious disease outbreaks and bioterrorist attacks," Annals of Operations Research, Springer, vol. 148(1), pages 25-53, November.
    2. Ubaid Illahi & Mohammad Shafi Mir, 2021. "Maintaining efficient logistics and supply chain management operations during and after coronavirus (COVID-19) pandemic: learning from the past experiences," Environment, Development and Sustainability: A Multidisciplinary Approach to the Theory and Practice of Sustainable Development, Springer, vol. 23(8), pages 11157-11178, August.
    3. Konstantinos S. Boulas & Georgios D. Dounias & Chrissoleon T. Papadopoulos, 2023. "A hybrid evolutionary algorithm approach for estimating the throughput of short reliable approximately balanced production lines," Journal of Intelligent Manufacturing, Springer, vol. 34(2), pages 823-852, February.
    4. Papadopoulos, H. T. & Heavey, C., 1996. "Queueing theory in manufacturing systems analysis and design: A classification of models for production and transfer lines," European Journal of Operational Research, Elsevier, vol. 92(1), pages 1-27, July.
    5. Papadopoulos, H. T. & Vidalis, M. I., 2001. "Minimizing WIP inventory in reliable production lines," International Journal of Production Economics, Elsevier, vol. 70(2), pages 185-197, March.
    6. Saied Samiedaluie & Vedat Verter, 2019. "The impact of specialization of hospitals on patient access to care; a queuing analysis with an application to a neurological hospital," Health Care Management Science, Springer, vol. 22(4), pages 709-726, December.
    7. Elisa Gebennini & Andrea Grassi & Cesare Fantuzzi & Stanley Gershwin & Irvin Schick, 2013. "Discrete time model for two-machine one-buffer transfer lines with restart policy," Annals of Operations Research, Springer, vol. 209(1), pages 41-65, October.
    8. Michael Manitz, 2015. "Analysis of assembly/disassembly queueing networks with blocking after service and general service times," Annals of Operations Research, Springer, vol. 226(1), pages 417-441, March.
    9. Osorio, Carolina & Bierlaire, Michel, 2012. "A tractable analytical model for large-scale congested protein synthesis networks," European Journal of Operational Research, Elsevier, vol. 219(3), pages 588-597.
    10. Elisa Gebennini & Andrea Grassi & Cesare Fantuzzi, 2015. "The two-machine one-buffer continuous time model with restart policy," Annals of Operations Research, Springer, vol. 231(1), pages 33-64, August.
    11. Jean-Sébastien Tancrez, 2020. "A decomposition method for assembly/disassembly systems with blocking and general distributions," Flexible Services and Manufacturing Journal, Springer, vol. 32(2), pages 272-296, June.
    12. Maria da Conceição Cunha, 1999. "On Solving Aquifer Management Problems with Simulated Annealing Algorithms," Water Resources Management: An International Journal, Published for the European Water Resources Association (EWRA), Springer;European Water Resources Association (EWRA), vol. 13(3), pages 153-170, June.
    13. Ali Asgary & Svetozar Zarko Valtchev & Michael Chen & Mahdi M. Najafabadi & Jianhong Wu, 2020. "Artificial Intelligence Model of Drive-Through Vaccination Simulation," IJERPH, MDPI, vol. 18(1), pages 1-10, December.
    14. Meyr, H., 2000. "Simultaneous lotsizing and scheduling by combining local search with dual reoptimization," European Journal of Operational Research, Elsevier, vol. 120(2), pages 311-326, January.
    15. David Simchi-Levi & Nikolaos Trichakis & Peter Yun Zhang, 2019. "Designing Response Supply Chain Against Bioattacks," Operations Research, INFORMS, vol. 67(5), pages 1246-1268, September.
    16. Ganesan, Viswanath Kumar & Sivakumar, Appa Iyer, 2006. "Scheduling in static jobshops for minimizing mean flowtime subject to minimum total deviation of job completion times," International Journal of Production Economics, Elsevier, vol. 103(2), pages 633-647, October.
    17. Alain Patchong & Thierry Lemoine & Gilles Kern, 2003. "Improving Car Body Production at PSA Peugeot Citroën," Interfaces, INFORMS, vol. 33(1), pages 36-49, February.
    18. P. Daniel Wright & Matthew J. Liberatore & Robert L. Nydick, 2006. "A Survey of Operations Research Models and Applications in Homeland Security," Interfaces, INFORMS, vol. 36(6), pages 514-529, December.
    19. H. A. J. Crauwels & C. N. Potts & L. N. Van Wassenhove, 1998. "Local Search Heuristics for the Single Machine Total Weighted Tardiness Scheduling Problem," INFORMS Journal on Computing, INFORMS, vol. 10(3), pages 341-350, August.
    20. M Kumral & P A Dowd, 2005. "A simulated annealing approach to mine production scheduling," Journal of the Operational Research Society, Palgrave Macmillan;The OR Society, vol. 56(8), pages 922-930, August.

    Corrections

    All material on this site has been provided by the respective publishers and authors. You can help correct errors and omissions. When requesting a correction, please mention this item's handle: RePEc:inm:orinte:v:36:y:2006:i:6:p:591-607. See general information about how to correct material in RePEc.

    If you have authored this item and are not yet registered with RePEc, we encourage you to do it here. This allows to link your profile to this item. It also allows you to accept potential citations to this item that we are uncertain about.

    If CitEc recognized a bibliographic reference but did not link an item in RePEc to it, you can help with this form .

    If you know of missing items citing this one, you can help us creating those links by adding the relevant references in the same way as above, for each refering item. If you are a registered author of this item, you may also want to check the "citations" tab in your RePEc Author Service profile, as there may be some citations waiting for confirmation.

    For technical questions regarding this item, or to correct its authors, title, abstract, bibliographic or download information, contact: Chris Asher (email available below). General contact details of provider: https://edirc.repec.org/data/inforea.html .

    Please note that corrections may take a couple of weeks to filter through the various RePEc services.

    IDEAS is a RePEc service. RePEc uses bibliographic data supplied by the respective publishers.