IDEAS home Printed from https://ideas.repec.org/a/gam/jijerp/v20y2023i6p4979-d1094768.html
   My bibliography  Save this article

Clustering of Environmental Parameters and the Risk of Acute Ischaemic Stroke

Author

Listed:
  • Geraldine P. Y. Koo

    (Ministry of Health Holdings, Singapore 099253, Singapore)

  • Huili Zheng

    (National Registry of Diseases Officer, Health Promotion Board, Singapore 168937, Singapore)

  • Joel C. L. Aik

    (Environmental Epidemiology and Toxicology Division, Environmental Health Institute, National Environment Agency, Singapore 228231, Singapore
    Pre-Hospital & Emergency Research Center, Duke-NUS Medical School, Singapore 169857, Singapore)

  • Benjamin Y. Q. Tan

    (Division of Neurology, Department of Medicine, National University Hospital, Singapore 119074, Singapore
    Yong Loo Lin School of Medicine, National University of Singapore, Singapore 119228, Singapore)

  • Vijay K. Sharma

    (Division of Neurology, Department of Medicine, National University Hospital, Singapore 119074, Singapore
    Yong Loo Lin School of Medicine, National University of Singapore, Singapore 119228, Singapore)

  • Ching Hui Sia

    (Yong Loo Lin School of Medicine, National University of Singapore, Singapore 119228, Singapore
    Department of Cardiology, National University Heart Centre Singapore, Singapore 119074, Singapore)

  • Marcus E. H. Ong

    (Health Services & Systems Research, Duke-NUS Medical School, Singapore 169857, Singapore
    Department of Emergency Medicine, Singapore General Hospital, Singapore 169608, Singapore)

  • Andrew F. W. Ho

    (Pre-Hospital & Emergency Research Center, Duke-NUS Medical School, Singapore 169857, Singapore
    Department of Emergency Medicine, Singapore General Hospital, Singapore 169608, Singapore
    Centre of Population Health Research and Implementation, SingHealth Regional Health System, Singapore 168753, Singapore
    Saw Swee Hock School of Public Health, National University of Singapore, Singapore 117549, Singapore)

Abstract

Acute ischaemic stroke (AIS) risk on days with similar environmental profiles remains unknown. We investigated the association between clusters of days with similar environmental parameters and AIS incidence in Singapore. We grouped calendar days from 2010 to 2015 with similar rainfall, temperature, wind speed, and Pollutant Standards Index (PSI) using k-means clustering. Three distinct clusters were formed ‘Cluster 1’ containing high wind speed, ‘Cluster 2’ having high rainfall, and ‘Cluster 3’ having high temperatures and PSI. We aggregated the number of AIS episodes over the same period with the clusters and analysed their association using a conditional Poisson regression in a time-stratified case-crossover design. Comparing the three clusters, Cluster 3 had the highest AIS occurrence (IRR 1.09; 95% confidence interval (CI) 1.05–1.13), with no significant difference between Clusters 1 and 2. Subgroup analyses in Cluster 3 showed that AIS risk was amplified in the elderly (≥65 years old), non-smokers, and those without a history of ischaemic heart disease/atrial fibrillation/vascular heart disease/peripheral vascular disease. In conclusion, we found that AIS incidence may be higher on days with higher temperatures and PSI. These findings have important public health implications for AIS prevention and health services delivery during at-risk days, such as during the seasonal transboundary haze.

Suggested Citation

  • Geraldine P. Y. Koo & Huili Zheng & Joel C. L. Aik & Benjamin Y. Q. Tan & Vijay K. Sharma & Ching Hui Sia & Marcus E. H. Ong & Andrew F. W. Ho, 2023. "Clustering of Environmental Parameters and the Risk of Acute Ischaemic Stroke," IJERPH, MDPI, vol. 20(6), pages 1-10, March.
    • Handle: RePEc:gam:jijerp:v:20:y:2023:i:6:p:4979-:d:1094768
    as

    Download full text from publisher

    File URL: https://www.mdpi.com/1660-4601/20/6/4979/pdf
    Download Restriction: no
    File URL: https://www.mdpi.com/1660-4601/20/6/4979/
    Download Restriction: no
    ---><---

    References listed on IDEAS

    as
    1. Yaohua Tian & Hui Liu & Zuolin Zhao & Xiao Xiang & Man Li & Juan Juan & Jing Song & Yaying Cao & Xiaowen Wang & Libo Chen & Chen Wei & Yonghua Hu & Pei Gao, 2018. "Association between ambient air pollution and daily hospital admissions for ischemic stroke: A nationwide time-series analysis," PLOS Medicine, Public Library of Science, vol. 15(10), pages 1-16, October.
    2. Antonis Analitis & Francesca De’ Donato & Matteo Scortichini & Timo Lanki & Xavier Basagana & Ferran Ballester & Christopher Astrom & Anna Paldy & Mathilde Pascal & Antonio Gasparrini & Paola Micheloz, 2018. "Synergistic Effects of Ambient Temperature and Air Pollution on Health in Europe: Results from the PHASE Project," IJERPH, MDPI, vol. 15(9), pages 1-11, August.
    3. Xia Wang & Yongjun Cao & Daqing Hong & Danni Zheng & Sarah Richtering & Else Charlotte Sandset & Tzen Hugh Leong & Hisatomi Arima & Shariful Islam & Abdul Salam & Craig Anderson & Thompson Robinson & , 2016. "Ambient Temperature and Stroke Occurrence: A Systematic Review and Meta-Analysis," IJERPH, MDPI, vol. 13(7), pages 1-12, July.
    4. Hui Lian & Yanping Ruan & Ruijuan Liang & Xiaole Liu & Zhongjie Fan, 2015. "Short-Term Effect of Ambient Temperature and the Risk of Stroke: A Systematic Review and Meta-Analysis," IJERPH, MDPI, vol. 12(8), pages 1-21, July.
    5. Narayan Sastry, 2002. "Forest fires, air pollution, and mortality in Southeast Asia," Demography, Springer;Population Association of America (PAA), vol. 39(1), pages 1-23, February.
    6. Miriam E. Marlier & Ruth S. DeFries & Apostolos Voulgarakis & Patrick L. Kinney & James T. Randerson & Drew T. Shindell & Yang Chen & Greg Faluvegi, 2013. "El Niño and health risks from landscape fire emissions in southeast Asia," Nature Climate Change, Nature, vol. 3(2), pages 131-136, February.
    Full references (including those not matched with items on IDEAS)

    Most related items

    These are the items that most often cite the same works as this one and are cited by the same works as this one.
    1. Geraldine P. Y. Koo & Huili Zheng & Pin Pin Pek & Fintan Hughes & Shir Lynn Lim & Jun Wei Yeo & Marcus E. H. Ong & Andrew F. W. Ho, 2022. "Clustering of Environmental Parameters and the Risk of Acute Myocardial Infarction," IJERPH, MDPI, vol. 19(14), pages 1-12, July.
    2. Constantina Kopitsa & Ioannis G. Tsoulos & Vasileios Charilogis & Athanassios Stavrakoudis, 2024. "Predicting the Duration of Forest Fires Using Machine Learning Methods," Future Internet, MDPI, vol. 16(11), pages 1-19, October.
    3. Annie Young Song, 2023. "Beyond intergovernmental cooperation: domestic politics of transboundary air pollution in Korea and Singapore," International Environmental Agreements: Politics, Law and Economics, Springer, vol. 23(4), pages 397-413, December.
    4. Pierre Masselot & Fateh Chebana & Taha B. M. J. Ouarda & Diane Bélanger & Pierre Gosselin, 2022. "Data-Enhancement Strategies in Weather-Related Health Studies," IJERPH, MDPI, vol. 19(2), pages 1-13, January.
    5. Seema Jayachandran, 2009. "Air Quality and Early-Life Mortality: Evidence from Indonesia’s Wildfires," Journal of Human Resources, University of Wisconsin Press, vol. 44(4).
    6. Agnieszka Jakubowska & Marcin Rabe, 2022. "Air Pollution and Limitations in Health: Identification of Inequalities in the Burdens of the Economies of the “Old” and “New” EU," Energies, MDPI, vol. 15(17), pages 1-16, August.
    7. Jayanthi Rajarethinam & Joel Aik & Jing Tian, 2020. "The Influence of South East Asia Forest Fires on Ambient Particulate Matter Concentrations in Singapore: An Ecological Study Using Random Forest and Vector Autoregressive Models," IJERPH, MDPI, vol. 17(24), pages 1-14, December.
    8. Lawrence A. Palinkas & Jessenia De Leon & Kexin Yu & Erika Salinas & Cecilia Fernandez & Jill Johnston & Md Mostafijur Rahman & Sam J. Silva & Michael Hurlburt & Rob S. McConnell & Erika Garcia, 2023. "Adaptation Resources and Responses to Wildfire Smoke and Other Forms of Air Pollution in Low-Income Urban Settings: A Mixed-Methods Study," IJERPH, MDPI, vol. 20(7), pages 1-16, April.
    9. Datar, Ashlesha & Liu, Jenny & Linnemayr, Sebastian & Stecher, Chad, 2013. "The impact of natural disasters on child health and investments in rural India," Social Science & Medicine, Elsevier, vol. 76(C), pages 83-91.
    10. Seema Jayachandran, 2005. "Air Quality and Infant Mortality During Indonesia's Massive Wildfires in 1997," UCLA Economics Online Papers 358, UCLA Department of Economics.
    11. William Groot & Robert Field & Michael Brady & Orbita Roswintiarti & Maznorizan Mohamad, 2007. "Development of the Indonesian and Malaysian Fire Danger Rating Systems," Mitigation and Adaptation Strategies for Global Change, Springer, vol. 12(1), pages 165-180, January.
    12. Kim, Younoh & Knowles, Scott & Manley, James & Radoias, Vlad, 2017. "Long-run health consequences of air pollution: Evidence from Indonesia's forest fires of 1997," Economics & Human Biology, Elsevier, vol. 26(C), pages 186-198.
    13. Pierre Masselot & Fateh Chebana & Éric Lavigne & Céline Campagna & Pierre Gosselin & Taha B.M.J. Ouarda, 2019. "Toward an Improved Air Pollution Warning System in Quebec," IJERPH, MDPI, vol. 16(12), pages 1-14, June.
    14. Tommaso Sonno & Davide Zufacchi, 2022. "Epidemics and rapacity of multinational companies," CEP Discussion Papers dp1833, Centre for Economic Performance, LSE.
    15. Bladimir Carrillo & Danyelle K. Branco & Juan C. Trujillo & João E. Lima, 2019. "The Externalities of a Deforestation Control Policy in Infant Health: Evidence from Brazil," Economic Development and Cultural Change, University of Chicago Press, vol. 67(2), pages 369-400.
    16. Tingru Yang & Wenling Liu, 2019. "Health Effects of Energy Intensive Sectors and the Potential Health Co-Benefits of a Low Carbon Industrial Transition in China," IJERPH, MDPI, vol. 16(17), pages 1-18, August.
    17. Zesheng Chen & Bin Wang & Yanlin Hu & Lan Dai & Yangming Liu & Jing Wang & Xueqin Cao & Yiming Wu & Ting Zhou & Xiuqing Cui & Tingming Shi, 2022. "Short-Term Effects of Low-Level Ambient Air NO 2 on the Risk of Incident Stroke in Enshi City, China," IJERPH, MDPI, vol. 19(11), pages 1-13, May.
    18. Bo Sun & Bo Wang, 2021. "Spatial Spillover Effects of Air Pollution on the Health Expenditure of Rural Residents: Based on Spatial Durbin Model," IJERPH, MDPI, vol. 18(13), pages 1-11, July.
    19. Rashesh Shrestha, 2019. "Early Life Exposure to Air Pollution, Cognitive Development, and Labor Market Outcome," Asian Economic Papers, MIT Press, vol. 18(2), pages 77-95, Summer.
    20. Hassani Youssouf & Catherine Liousse & Laurent Roblou & Eric-Michel Assamoi & Raimo O. Salonen & Cara Maesano & Soutrik Banerjee & Isabella Annesi-Maesano, 2014. "Non-Accidental Health Impacts of Wildfire Smoke," IJERPH, MDPI, vol. 11(11), pages 1-33, November.

    Corrections

    All material on this site has been provided by the respective publishers and authors. You can help correct errors and omissions. When requesting a correction, please mention this item's handle: RePEc:gam:jijerp:v:20:y:2023:i:6:p:4979-:d:1094768. See general information about how to correct material in RePEc.

    If you have authored this item and are not yet registered with RePEc, we encourage you to do it here. This allows to link your profile to this item. It also allows you to accept potential citations to this item that we are uncertain about.

    If CitEc recognized a bibliographic reference but did not link an item in RePEc to it, you can help with this form .

    If you know of missing items citing this one, you can help us creating those links by adding the relevant references in the same way as above, for each refering item. If you are a registered author of this item, you may also want to check the "citations" tab in your RePEc Author Service profile, as there may be some citations waiting for confirmation.

    For technical questions regarding this item, or to correct its authors, title, abstract, bibliographic or download information, contact: MDPI Indexing Manager (email available below). General contact details of provider: https://www.mdpi.com .

    Please note that corrections may take a couple of weeks to filter through the various RePEc services.

    IDEAS is a RePEc service. RePEc uses bibliographic data supplied by the respective publishers.