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Effects of Mindfulness-Based Cognitive Therapy on Major Depressive Disorder with Multiple Episodes: A Systematic Review and Meta-Analysis

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  • Hui-Wen Tseng

    (School of Nursing, Fooyin University, Kaohsiung 831301, Taiwan
    College of Nursing, Kaohsiung Medical University, Kaohsiung 807378, Taiwan
    This author contributed equally to this work as the first author.)

  • Fan-Hao Chou

    (College of Nursing, Kaohsiung Medical University, Kaohsiung 807378, Taiwan)

  • Ching-Hsiu Chen

    (School of Nursing, Fooyin University, Kaohsiung 831301, Taiwan)

  • Yu-Ping Chang

    (School of Nursing, University at Buffalo, The State University of New York, Buffalo, NY 14260, USA)

Abstract

This study synthesizes the effect of mindfulness-based cognitive therapy (MBCT) on depression and suicidal ideation among patients with major depressive disorder (MDD). During treatment, patients with MDD may experience repeated episodes, negative counseling, and suicidal ideation, which can lead to further depression and ultimately affect quality of life. Recent studies have shown that MBCT can improve the level of depression and suicidal ideation in patients with MDD. A systematic review and meta-analysis of randomized controlled trials was conducted. The literature search for articles up to December 2021 was performed in the following electronic databases: Airiti Library, PsycINFO, CINAHL, Cochrane Library, PubMed/MEDLINE, ProQuest, and the Index of the Taiwan Periodical Literature System. Records were independently evaluated by two reviewers. Disagreements were resolved through consensus. The quality of study was evaluated using the Modified Jadad Scale score. A meta-analysis was performed using Review Manager Version 5.3.5 software with a random-effects model. Thirteen studies (1159 participants) investigating MBCT for patients with MDD were included. The MBCT sessions lasted 1.5–2.5 h and were delivered by therapists five times per week for 8 weeks. The meta-effects of MBCT among patients with MDD showed significant improvement in depression and suicidal ideation. Future research should evaluate the long-term effects of MBCT. MBCT is relatively convenient and effective for preventing and alleviating depression and suicidal ideation. Further research can provide detailed suggestions for effective MBCT implementation.

Suggested Citation

  • Hui-Wen Tseng & Fan-Hao Chou & Ching-Hsiu Chen & Yu-Ping Chang, 2023. "Effects of Mindfulness-Based Cognitive Therapy on Major Depressive Disorder with Multiple Episodes: A Systematic Review and Meta-Analysis," IJERPH, MDPI, vol. 20(2), pages 1-16, January.
    • Handle: RePEc:gam:jijerp:v:20:y:2023:i:2:p:1555-:d:1036102
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    References listed on IDEAS

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    1. Alessandro Liberati & Douglas G Altman & Jennifer Tetzlaff & Cynthia Mulrow & Peter C Gøtzsche & John P A Ioannidis & Mike Clarke & P J Devereaux & Jos Kleijnen & David Moher, 2009. "The PRISMA Statement for Reporting Systematic Reviews and Meta-Analyses of Studies That Evaluate Health Care Interventions: Explanation and Elaboration," PLOS Medicine, Public Library of Science, vol. 6(7), pages 1-28, July.
    2. Fragkos, Konstantinos C. & Tsagris, Michail & Frangos, Christos C., 2014. "Publication Bias in Meta-Analysis: Confidence Intervals for Rosenthal’s Fail-Safe Number," MPRA Paper 66451, University Library of Munich, Germany.
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