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Multi-Scale Multivariate Models for Small Area Health Survey Data: A Chilean Example

Author

Listed:
  • Andrew Lawson

    (Department of Public Health Sciences, Medical University of South Carolina, Charleston, SC 29466, USA)

  • Anna Schritz

    (Luxembourg Institute of Health, 1A-B, rue Thomas Edison, Strassen, L-1445 Luxembourg City, Luxembourg)

  • Luis Villarroel

    (Public Health Department, School of Medicine, Pontificia Universidad Católica de Chile, Diagonal Paraguay 362, Santiago 8330077, Chile)

  • Gloria A. Aguayo

    (Luxembourg Institute of Health, 1A-B, rue Thomas Edison, Strassen, L-1445 Luxembourg City, Luxembourg)

Abstract

Background: We propose a general approach to the analysis of multivariate health outcome data where geo-coding at different spatial scales is available. We propose multiscale joint models which address the links between individual outcomes and also allow for correlation between areas. The models are highly novel in that they exploit survey data to provide multiscale estimates of the prevalences in small areas for a range of disease outcomes. Results The models incorporate both disease specific, and common disease spatially structured components. The multiple scales envisaged is where individual survey data is used to model regional prevalences or risks at an aggregate scale. This approach involves the use of survey weights as predictors within our Bayesian multivariate models. Missingness has to be addressed within these models and we use predictive inference which exploits the correlation between diseases to provide estimates of missing prevalances. The Case study we examine is from the National Health Survey of Chile where geocoding to Province level is available. In that survey, diabetes, Hypertension, obesity and elevated low-density cholesterol (LDL) are available but differential missingness requires that aggregation of estimates and also the assumption of smoothed sampling weights at the aggregate level. Conclusions: The methodology proposed is highly novel and flexibly handles multiple disease outcomes at individual and aggregated levels (i.e., multiscale joint models). The missingness mechanism adopted provides realistic estimates for inclusion in the aggregate model at Provincia level. The spatial structure of four diseases within Provincias has marked spatial differentiation, with diabetes and hypertension strongly clustered in central Provincias and obesity and LDL more clustered in the southern areas.

Suggested Citation

  • Andrew Lawson & Anna Schritz & Luis Villarroel & Gloria A. Aguayo, 2020. "Multi-Scale Multivariate Models for Small Area Health Survey Data: A Chilean Example," IJERPH, MDPI, vol. 17(5), pages 1-20, March.
  • Handle: RePEc:gam:jijerp:v:17:y:2020:i:5:p:1682-:d:328550
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    References listed on IDEAS

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    1. Julian Besag & Jeremy York & Annie Mollié, 1991. "Bayesian image restoration, with two applications in spatial statistics," Annals of the Institute of Statistical Mathematics, Springer;The Institute of Statistical Mathematics, vol. 43(1), pages 1-20, March.
    2. Raghunathan, Trivellore E. & Xie, Dawei & Schenker, Nathaniel & Parsons, Van L. & Davis, William W. & Dodd, Kevin W. & Feuer, Eric J., 2007. "Combining Information From Two Surveys to Estimate County-Level Prevalence Rates of Cancer Risk Factors and Screening," Journal of the American Statistical Association, American Statistical Association, vol. 102, pages 474-486, June.
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