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Bayesian regression analysis of data with random effects covariates from nonlinear longitudinal measurements

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  • De la Cruz, Rolando
  • Meza, Cristian
  • Arribas-Gil, Ana
  • Carroll, Raymond J.

Abstract

Joint models for a wide class of response variables and longitudinal measurements consist on a mixed-effects model to fit longitudinal trajectories whose random effects enter as covariates in a generalized linear model for the primary response. They provide a useful way to assess association between these two kinds of data, which in clinical studies are often collected jointly on a series of individuals and may help understanding, for instance, the mechanisms of recovery of a certain disease or the efficacy of a given therapy. When a nonlinear mixed-effects model is used to fit the longitudinal trajectories, the existing estimation strategies based on likelihood approximations have been shown to exhibit some computational efficiency problems (De la Cruz et al., 2011). In this article we consider a Bayesian estimation procedure for the joint model with a nonlinear mixed-effects model for the longitudinal data and a generalized linear model for the primary response. The proposed prior structure allows for the implementation of an MCMC sampler. Moreover, we consider that the errors in the longitudinal model may be correlated. We apply our method to the analysis of hormone levels measured at the early stages of pregnancy that can be used to predict normal versus abnormal pregnancy outcomes. We also conduct a simulation study to assess the importance of modelling correlated errors and quantify the consequences of model misspecification.

Suggested Citation

  • De la Cruz, Rolando & Meza, Cristian & Arribas-Gil, Ana & Carroll, Raymond J., 2016. "Bayesian regression analysis of data with random effects covariates from nonlinear longitudinal measurements," Journal of Multivariate Analysis, Elsevier, vol. 143(C), pages 94-106.
  • Handle: RePEc:eee:jmvana:v:143:y:2016:i:c:p:94-106
    DOI: 10.1016/j.jmva.2015.08.020
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    References listed on IDEAS

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    1. Ghosh, Pulak & Tu, Wanzhu, 2009. "Assessing Sexual Attitudes and Behaviors of Young Women: A Joint Model with Nonlinear Time Effects, Time Varying Covariates, and Dropouts," Journal of the American Statistical Association, American Statistical Association, vol. 104(486), pages 474-485.
    2. Elizabeth R. Brown & Joseph G. Ibrahim, 2003. "Bayesian Approaches to Joint Cure-Rate and Longitudinal Models with Applications to Cancer Vaccine Trials," Biometrics, The International Biometric Society, vol. 59(3), pages 686-693, September.
    3. Joe, Harry, 2008. "Accuracy of Laplace approximation for discrete response mixed models," Computational Statistics & Data Analysis, Elsevier, vol. 52(12), pages 5066-5074, August.
    4. C. Y. Wang & Naisyin Wang & Suojin Wang, 2000. "Regression Analysis When Covariates Are Regression Parameters of a Random Effects Model for Observed Longitudinal Measurements," Biometrics, The International Biometric Society, vol. 56(2), pages 487-495, June.
    5. Erning Li & Daowen Zhang & Marie Davidian, 2004. "Conditional Estimation for Generalized Linear Models When Covariates Are Subject-Specific Parameters in a Mixed Model for Longitudinal Measurements," Biometrics, The International Biometric Society, vol. 60(1), pages 1-7, March.
    6. Rolando De la Cruz‐Mesía & Fernando A. Quintana & Peter Müller, 2007. "Semiparametric Bayesian classification with longitudinal markers," Journal of the Royal Statistical Society Series C, Royal Statistical Society, vol. 56(2), pages 119-137, March.
    7. Hobert, James P. & Geyer, Charles J., 1998. "Geometric Ergodicity of Gibbs and Block Gibbs Samplers for a Hierarchical Random Effects Model," Journal of Multivariate Analysis, Elsevier, vol. 67(2), pages 414-430, November.
    8. L. Wu & W. Liu & X. J. Hu, 2010. "Joint Inference on HIV Viral Dynamics and Immune Suppression in Presence of Measurement Errors," Biometrics, The International Biometric Society, vol. 66(2), pages 327-335, June.
    9. Guo X. & Carlin B.P., 2004. "Separate and Joint Modeling of Longitudinal and Event Time Data Using Standard Computer Packages," The American Statistician, American Statistical Association, vol. 58, pages 16-24, February.
    10. Gareth M. James, 2002. "Generalized linear models with functional predictors," Journal of the Royal Statistical Society Series B, Royal Statistical Society, vol. 64(3), pages 411-432, August.
    11. Elizabeth R. Brown & Joseph G. Ibrahim & Victor DeGruttola, 2005. "A Flexible B-Spline Model for Multiple Longitudinal Biomarkers and Survival," Biometrics, The International Biometric Society, vol. 61(1), pages 64-73, March.
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    1. Héctor Araya & Meryem Slaoui & Soledad Torres, 2022. "Bayesian inference for fractional Oscillating Brownian motion," Computational Statistics, Springer, vol. 37(2), pages 887-907, April.

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