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Operational issues and network effects in vaccine markets

Author

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  • Adida, Elodie
  • Dey, Debabrata
  • Mamani, Hamed

Abstract

One of the most important concerns for managing public health is the prevention of infectious diseases. Although vaccines provide the most effective means for preventing infectious diseases, there are two main reasons why it is often difficult to reach a socially optimal level of vaccine coverage: (i) the emergence of operational issues (such as yield uncertainty) on the supply side, and (ii) the existence of negative network effects on the consumption side. In particular, uncertainties about production yield and vaccine imperfections often make manufacturing some vaccines a risky process and may lead the manufacturer to produce below the socially optimal level. At the same time, negative network effects provide incentives to potential consumers to free ride off the immunity of the vaccinated population. In this research, we consider how a central policy-maker can induce a socially optimal vaccine coverage through the use of incentives to both consumers and the vaccine manufacturer. We consider a monopoly market for an imperfect vaccine; we show that a fixed two-part subsidy is unable to coordinate the market, but derive a two-part menu of subsidies that leads to a socially efficient level of coverage.

Suggested Citation

  • Adida, Elodie & Dey, Debabrata & Mamani, Hamed, 2013. "Operational issues and network effects in vaccine markets," European Journal of Operational Research, Elsevier, vol. 231(2), pages 414-427.
  • Handle: RePEc:eee:ejores:v:231:y:2013:i:2:p:414-427
    DOI: 10.1016/j.ejor.2013.05.034
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    References listed on IDEAS

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    Cited by:

    1. Tinglong Dai & Soo-Haeng Cho & Fuqiang Zhang, 2016. "Contracting for On-Time Delivery in the U.S. Influenza Vaccine Supply Chain," Manufacturing & Service Operations Management, INFORMS, vol. 18(3), pages 332-346, July.
    2. Feiyu Guo & Erbao Cao, 2020. "Does Reference Dependence Impact Intervention Mechanisms in Vaccine Markets?," Sustainability, MDPI, vol. 12(16), pages 1-28, August.
    3. Lin, Qi & Zhao, Qiuhong & Lev, Benjamin, 2022. "Influenza vaccine supply chain coordination under uncertain supply and demand," European Journal of Operational Research, Elsevier, vol. 297(3), pages 930-948.
    4. Osman Y. Özaltın & Oleg A. Prokopyev & Andrew J. Schaefer, 2018. "Optimal Design of the Seasonal Influenza Vaccine with Manufacturing Autonomy," INFORMS Journal on Computing, INFORMS, vol. 30(2), pages 371-387, May.
    5. Goodkin-Gold, Matthew & Kremer, Michael & Snyder, Christopher M. & Williams, Heidi, 2022. "Optimal vaccine subsidies for endemic diseases," International Journal of Industrial Organization, Elsevier, vol. 84(C).
    6. Guo, Feiyu & Cao, Erbao, 2021. "Can reference points explain vaccine hesitancy? A new perspective on their formation and updating," Omega, Elsevier, vol. 99(C).
    7. Westerink-Duijzer, L.E. & Schlicher, L.P.J. & Musegaas, M., 2019. "Fair allocations for cooperation problems in vaccination," Econometric Institute Research Papers EI2019-06, Erasmus University Rotterdam, Erasmus School of Economics (ESE), Econometric Institute.
    8. Xie, Lei & Hou, Pengwen & Han, Hongshuai, 2021. "Implications of government subsidy on the vaccine product R&D when the buyer is risk averse," Transportation Research Part E: Logistics and Transportation Review, Elsevier, vol. 146(C).
    9. Duijzer, Lotty Evertje & van Jaarsveld, Willem & Dekker, Rommert, 2018. "The benefits of combining early aspecific vaccination with later specific vaccination," European Journal of Operational Research, Elsevier, vol. 271(2), pages 606-619.
    10. Lunday, Brian J. & Robbins, Matthew J., 2019. "Collaboratively-developed vaccine pricing and stable profit sharing mechanisms," Omega, Elsevier, vol. 84(C), pages 102-113.
    11. Alexandar Angelus & Özalp Özer, 2022. "On the large‐scale production of a new vaccine," Production and Operations Management, Production and Operations Management Society, vol. 31(7), pages 3043-3060, July.
    12. Saed Alizamir & Foad Iravani & Hamed Mamani, 2019. "An Analysis of Price vs. Revenue Protection: Government Subsidies in the Agriculture Industry," Management Science, INFORMS, vol. 65(1), pages 32-49, January.
    13. Hammami, Ramzi & Salman, Sinan & Khouja, Moutaz & Nouira, Imen & Alaswad, Suzan, 2023. "Government strategies to secure the supply of medical products in pandemic times," European Journal of Operational Research, Elsevier, vol. 306(3), pages 1364-1387.
    14. Duijzer, Lotty Evertje & van Jaarsveld, Willem & Dekker, Rommert, 2018. "Literature review: The vaccine supply chain," European Journal of Operational Research, Elsevier, vol. 268(1), pages 174-192.
    15. Lotty E. Westerink‐Duijzer & Loe P. J. Schlicher & Marieke Musegaas, 2020. "Core Allocations for Cooperation Problems in Vaccination," Production and Operations Management, Production and Operations Management Society, vol. 29(7), pages 1720-1737, July.
    16. Ece Zeliha Demirci & Nesim Kohen Erkip, 2020. "Designing intervention scheme for vaccine market: a bilevel programming approach," Flexible Services and Manufacturing Journal, Springer, vol. 32(2), pages 453-485, June.
    17. Wang, Fan & Xu, Danni & Zhuo, Xiaopo & Zhang, Chao & Liu, Yaoqi, 2022. "Improving consumer welfare in vaccine market: Pricing, government subsidies and consumer awareness," Transportation Research Part E: Logistics and Transportation Review, Elsevier, vol. 167(C).
    18. Stephen E. Chick & Sameer Hasija & Javad Nasiry, 2017. "Information Elicitation and Influenza Vaccine Production," Operations Research, INFORMS, vol. 65(1), pages 75-96, February.
    19. Hu, Hui & Xu, Jiajun & Liu, Mengqi & Lim, Ming K., 2023. "Vaccine supply chain management: An intelligent system utilizing blockchain, IoT and machine learning," Journal of Business Research, Elsevier, vol. 156(C).
    20. Robbins, Matthew J. & Lunday, Brian J., 2016. "A bilevel formulation of the pediatric vaccine pricing problem," European Journal of Operational Research, Elsevier, vol. 248(2), pages 634-645.
    21. Hongmei Sun & Fuminori Toyasaki & Ioanna Falagara Sigala, 2023. "Incentivizing at‐risk production capacity building for COVID‐19 vaccines," Production and Operations Management, Production and Operations Management Society, vol. 32(5), pages 1550-1566, May.
    22. Stephen E. Chick & Sameer Hasija & Javad Nasiry, 2017. "Information Elicitation and Influenza Vaccine Production," Operations Research, INFORMS, vol. 65(1), pages 75-96, February.
    23. Choudhury, Nishat Alam & Ramkumar, M. & Schoenherr, Tobias & Singh, Shalabh, 2023. "The role of operations and supply chain management during epidemics and pandemics: Potential and future research opportunities," Transportation Research Part E: Logistics and Transportation Review, Elsevier, vol. 175(C).

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