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Stem Cell Donor Matching for Patients of Mixed Race

Author

Listed:
  • Bergstrom Ted C.

    (University of California, Santa Barbara)

  • Garratt Rod

    (University of California, Santa Barbara)

  • Sheehan-Connor Damien

    (Wesleyan University)

Abstract

Much attention has been given to the plight of minorities and persons of mixed race in need of a bone marrow transplant. This has led to increased efforts to recruit minority and mixed-race donors. There is strong evidence that members of racial minorities are less likely to find a match than those of European descent. Because the relevant sample sizes are small, direct estimation of the distribution of immunity types for mixed-race populations have not been available. We show how to estimate the distribution of HLA types for persons of mixed race indirectly, using simple principles of probability and the combinatorics of diploid reproduction. We show that recruitment of mixed race donors is cost-effective, but not for the expected reasons. While recruitment of mixed-race donors increases the welfare of patients with the same racial background, the benefits to the targeted recipients do not exceed the costs. However, when account is taken of the likelihood that a mixed-race registrant will be the only available match for a patient classified as being of a single race, the recruitment of mixed race donors turns out to be highly cost-effective.

Suggested Citation

  • Bergstrom Ted C. & Garratt Rod & Sheehan-Connor Damien, 2012. "Stem Cell Donor Matching for Patients of Mixed Race," The B.E. Journal of Economic Analysis & Policy, De Gruyter, vol. 12(1), pages 1-27, July.
    • Handle: RePEc:bpj:bejeap:v:12:y:2012:i:1:n:30
    DOI: 10.1515/1935-1682.3275
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    References listed on IDEAS

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    1. Viscusi, W Kip & Aldy, Joseph E, 2003. "The Value of a Statistical Life: A Critical Review of Market Estimates throughout the World," Journal of Risk and Uncertainty, Springer, vol. 27(1), pages 5-76, August.
    2. Johannesson, Magnus & Johansson, Per-Olov & Lofgren, Karl-Gustaf, 1997. "On the Value of Changes in Life Expectancy: Blips versus Parametric Changes," Journal of Risk and Uncertainty, Springer, vol. 15(3), pages 221-239, December.
    3. Theodore C. Bergstrom & Rodney J. Garratt & Damien Sheehan-Connor, 2009. "One Chance in a Million: Altruism and the Bone Marrow Registry," American Economic Review, American Economic Association, vol. 99(4), pages 1309-1334, September.
    4. Jones-Lee, M W & Hammerton, M & Philips, P R, 1985. "The Value of Safety: Results of a National Sample Survey," Economic Journal, Royal Economic Society, vol. 95(377), pages 49-72, March.
    5. repec:reg:rpubli:282 is not listed on IDEAS
    6. Glenn C. Blomquist, 2004. "Self-Protection and Averting Behavior, Values of Statistical Lives, and Benefit Cost Analysis of Environmental Policy," Review of Economics of the Household, Springer, vol. 2(1), pages 89-110, March.
    7. Thomas J. Kniesner & W. Kip Viscusi & Christopher Woock & James P. Ziliak, 2012. "The Value of a Statistical Life: Evidence from Panel Data," The Review of Economics and Statistics, MIT Press, vol. 94(1), pages 74-87, February.
    8. DEHEZ, Pierre & DREZE, Jacques H., 1984. "State-dependent utility, the demand for insurance and the value of safety," LIDAM Reprints CORE 560, Université catholique de Louvain, Center for Operations Research and Econometrics (CORE).
    9. Zhenchao Qian, 2004. "Options: Racial/Ethnic Identification of Children of Intermarried Couples," Social Science Quarterly, Southwestern Social Science Association, vol. 85(3), pages 746-766, September.
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    Cited by:

    1. Judd B. Kessler & Alvin E. Roth, 2012. "Organ Allocation Policy and the Decision to Donate," American Economic Review, American Economic Association, vol. 102(5), pages 2018-2047, August.
    2. McTaggart, Ken & Killeen, Donna, 2018. "Modeling the optimal ethnic composition of an adult stem cell registryAuthor-Name: Blake, John T," European Journal of Operational Research, Elsevier, vol. 264(3), pages 884-893.
    3. Damien Sheehan-Connor & Theodore Bergstrom & Rodney Garratt, 2015. "Saving lives with stem cell transplants," Journal of Risk and Uncertainty, Springer, vol. 51(1), pages 23-51, August.
    4. Lacetera, Nicola & Macis, Mario & Stith, Sarah S., 2014. "Removing financial barriers to organ and bone marrow donation: The effect of leave and tax legislation in the U.S," Journal of Health Economics, Elsevier, vol. 33(C), pages 43-56.
    5. Eyting, Markus & Hosemann, Arne & Johannesson, Magnus, 2016. "Can monetary incentives increase organ donations?," Economics Letters, Elsevier, vol. 142(C), pages 56-58.
    6. Judd B. Kessler & Alvin E. Roth, 2014. "Don't Take 'No' For An Answer: An Experiment With Actual Organ Donor Registrations," NBER Working Papers 20378, National Bureau of Economic Research, Inc.

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    More about this item

    JEL classification:

    • H41 - Public Economics - - Publicly Provided Goods - - - Public Goods
    • H51 - Public Economics - - National Government Expenditures and Related Policies - - - Government Expenditures and Health

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