Stem Cell Donor Matching for Patients of Mixed Race
Much attention has been given to the plight of minorities and persons of mixed race in need of a bone marrow transplant. This has led to increased efforts to recruit minority and mixed-race donors. There is strong evidence that members of racial minorities are less likely to find a match than those of European descent. Because the relevant sample sizes are small, direct estimation of the distribution of immunity types for mixed-race populations have not been available. We show how to estimate the distribution of HLA types for persons of mixed race indirectly, using simple principles of probability and the combinatorics of diploid reproduction. We show that recruitment of mixed race donors is cost-effective, but not for the expected reasons. While recruitment of mixed-race donors increases the welfare of patients with the same racial background, the benefits to the targeted recipients do not exceed the costs. However, when account is taken of the likelihood that a mixed-race registrant will be the only available match for a patient classified as being of a single race, the recruitment of mixed race donors turns out to be highly cost-effective.
If you experience problems downloading a file, check if you have the proper application to view it first. In case of further problems read the IDEAS help page. Note that these files are not on the IDEAS site. Please be patient as the files may be large.
As the access to this document is restricted, you may want to look for a different version under "Related research" (further below) or search for a different version of it.
Volume (Year): 12 (2012)
Issue (Month): 1 (July)
|Contact details of provider:|| Web page: https://www.degruyter.com|
|Order Information:||Web: https://www.degruyter.com/view/j/bejeap|
References listed on IDEAS
Please report citation or reference errors to , or , if you are the registered author of the cited work, log in to your RePEc Author Service profile, click on "citations" and make appropriate adjustments.:
- Viscusi, W Kip & Aldy, Joseph E, 2003.
"The Value of a Statistical Life: A Critical Review of Market Estimates throughout the World,"
Journal of Risk and Uncertainty,
Springer, vol. 27(1), pages 5-76, August.
- W. Kip Viscusi & Joseph E. Aldy, 2003. "The Value of a Statistical Life: A Critical Review of Market Estimates throughout the World," NBER Working Papers 9487, National Bureau of Economic Research, Inc.
- Johannesson, Magnus & Johansson, Per-Olov & Lofgren, Karl-Gustaf, 1997. "On the Value of Changes in Life Expectancy: Blips versus Parametric Changes," Journal of Risk and Uncertainty, Springer, vol. 15(3), pages 221-239, December.
- Johannesson, Magnus & Johansson, Per-Olov & Löfgren, Karl-Gustaf, 1997. "On the Value of Changes in Life Expectancy: Blips versus Parametric Changes," SSE/EFI Working Paper Series in Economics and Finance 152, Stockholm School of Economics.
- Theodore C. Bergstrom & Rodney J. Garratt & Damien Sheehan-Connor, 2009. "One Chance in a Million: Altruism and the Bone Marrow Registry," American Economic Review, American Economic Association, vol. 99(4), pages 1309-1334, September.
- Theodore C. Bergstrom & Rod Garratt & Damien Sheehan-Connor, 2007. "One Chance in a Million: Altruism and the Bone Marrow Registry," CESifo Working Paper Series 2090, CESifo Group Munich.
- Bergstrom, Ted C & Garratt, Rod & Sheehan-Connor, Damien, 2008. "One Chance in a Million: Altruism and the Bone Marrow Registry," University of California at Santa Barbara, Economics Working Paper Series qt2xt1p3gf, Department of Economics, UC Santa Barbara.
- Jones-Lee, M W & Hammerton, M & Philips, P R, 1985. "The Value of Safety: Results of a National Sample Survey," Economic Journal, Royal Economic Society, vol. 95(377), pages 49-72, March.
- repec:reg:rpubli:282 is not listed on IDEAS
- Glenn C. Blomquist, 2004. "Self-Protection and Averting Behavior, Values of Statistical Lives, and Benefit Cost Analysis of Environmental Policy," Review of Economics of the Household, Springer, vol. 2(1), pages 89-110, 03.
- Glenn C. Blomquist, 2003. "Self Protection and Averting Behavior, Values of Statistical Lives, and Benefit Cost Analysis of Environmental Policy," NCEE Working Paper Series 200302, National Center for Environmental Economics, U.S. Environmental Protection Agency, revised Mar 2003.
- Thomas J. Kniesner & W. Kip Viscusi & Christopher Woock & James P. Ziliak, 2012. "The Value of a Statistical Life: Evidence from Panel Data," The Review of Economics and Statistics, MIT Press, vol. 94(1), pages 74-87, February.
- Thomas J. Kniesner & W. Kip Viscusi & Christopher Woock & James P. Ziliak, 2010. "The Value of a Statistical Life: Evidence from Panel Data," Center for Policy Research Working Papers 122, Center for Policy Research, Maxwell School, Syracuse University.
- DEHEZ, Pierre & DREZE, Jacques H., "undated". "State-dependent utility, the demand for insurance and the value of safety," CORE Discussion Papers RP 560, Université catholique de Louvain, Center for Operations Research and Econometrics (CORE).
- Zhenchao Qian, 2004. "Options: Racial/Ethnic Identification of Children of Intermarried Couples," Social Science Quarterly, Southwestern Social Science Association, vol. 85(3), pages 746-766. Full references (including those not matched with items on IDEAS)