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Content
August 2017, Volume 548, Issue 7665
- 97-102 In vivo FRET–FLIM reveals cell-type-specific protein interactions in Arabidopsis roots
by Yuchen Long & Yvonne Stahl & Stefanie Weidtkamp-Peters & Marten Postma & Wenkun Zhou & Joachim Goedhart & María-Isabel Sánchez-Pérez & Theodorus W. J. Gadella & Rüdiger Simon & Ben Scheres & Ikram Blilou - 103-107 Stimulation of functional neuronal regeneration from Müller glia in adult mice
by Nikolas L. Jorstad & Matthew S. Wilken & William N. Grimes & Stefanie G. Wohl & Leah S. VandenBosch & Takeshi Yoshimatsu & Rachel O. Wong & Fred Rieke & Thomas A. Reh - 108-111 Rapid elicitation of broadly neutralizing antibodies to HIV by immunization in cows
by Devin Sok & Khoa M. Le & Melissa Vadnais & Karen L. Saye-Francisco & Joseph G. Jardine & Jonathan L. Torres & Zachary T. Berndsen & Leopold Kong & Robyn Stanfield & Jennifer Ruiz & Alejandra Ramos & Chi-Hui Liang & Patricia L. Chen & Michael F. Criscitiello & Waithaka Mwangi & Ian A. Wilson & Andrew B. Ward & Vaughn V. Smider & Dennis R. Burton - 112-116 Fructose-1,6-bisphosphate and aldolase mediate glucose sensing by AMPK
by Chen-Song Zhang & Simon A. Hawley & Yue Zong & Mengqi Li & Zhichao Wang & Alexander Gray & Teng Ma & Jiwen Cui & Jin-Wei Feng & Mingjiang Zhu & Yu-Qing Wu & Terytty Yang Li & Zhiyun Ye & Shu-Yong Lin & Huiyong Yin & Hai-Long Piao & D. Grahame Hardie & Sheng-Cai Lin - 117-121 Complex cellular logic computation using ribocomputing devices
by Alexander A. Green & Jongmin Kim & Duo Ma & Pamela A. Silver & James J. Collins & Peng Yin - 122-122 Correction: Corrigendum: Modulating the therapeutic response of tumours to dietary serine and glycine starvation
by Oliver D. K. Maddocks & Dimitris Athineos & Eric C. Cheung & Pearl Lee & Tong Zhang & Niels J. F. van den Broek & Gillian M. Mackay & Christiaan F. Labuschagne & David Gay & Flore Kruiswijk & Julianna Blagih & David F. Vincent & Kirsteen J. Campbell & Fatih Ceteci & Owen J. Sansom & Karen Blyth & Karen H. Vousden - 122-122 Correction: Corrigendum: Crystal structure of the GLP-1 receptor bound to a peptide agonist
by Ali Jazayeri & Mathieu Rappas & Alastair J. H. Brown & James Kean & James C. Errey & Nathan J. Robertson & Cédric Fiez-Vandal & Stephen P. Andrews & Miles Congreve & Andrea Bortolato & Jonathan S. Mason & Asma H. Baig & Iryna Teobald & Andrew S. Doré & Malcolm Weir & Robert M. Cooke & Fiona H. Marshall - 123-124 Cybersecurity for the travelling scientist
by Brian Owens - 125-127 Training: A winning detour
by Chris Woolston - 127-127 Turning point: Data miner
by Virginia Gewin - 130-130 A life in the day of
by William Meikle
July 2017, Volume 547, Issue 7664
- 19-20 Can we predict protein from mRNA levels?
by Nikolaus Fortelny & Christopher M. Overall & Paul Pavlidis & Gabriela V. Cohen Freue - 23-23 Wilhelm et al. reply
by Mathias Wilhelm & Hannes Hahne & Mikhail Savitski & Harald Marx & Simone Lemeer & Marcus Bantscheff & Bernhard Kuster - 381-381 Don't run biomedical science as a business
by Michele Pagano - 387-388 Iceland drilling project aims to unearth how islands form
by Alexandra Witze - 388-389 US defence agencies grapple with gene drives
by Ewen Callaway - 389-389 Brain’s stem cells slow ageing in mice
by Sara Reardon - 390-391 Budding UK innovation agency gains cash — and clout
by Elizabeth Gibney - 391-392 Giant radio telescope scaled back to contain costs
by Sarah Wild - 394-396 China’s quest to become a space science superpower
by Jane Qiu - 397-399 Metrology is key to reproducing results
by Martyn Sené & Ian Gilmore & Jan-Theodoor Janssen - 400-401 Climate change: Al Gore gets inconvenient again
by Michael E. Mann - 401-402 In retrospect: Das Kapital
by Gareth Stedman Jones - 403-403 Open data: support from Swiss funder
by Matthias Egger & Angelika Kalt - 403-403 Open data: enforce materials sharing
by Joanne Kamens - 403-403 History's take on the atomic forge
by Michael Isaacson - 403-403 Factor in species' conservation value
by Axel Hochkirch - 403-403 Alternative telescope site is a good back-up
by Sergio Bonaque-González - 406-407 How fish feel the flow
by John O. Dabiri - 407-408 A new spin on nanoscale computing
by Frank Hoppensteadt - 408-410 Synapses get together for vision
by Tobias Rose & Mark Hübener - 410-411 Molecular structure assignment simplified
by Severin K. Thompson & Thomas R. Hoye - 411-412 Towards polio eradication
by Jaime Sepúlveda - 413-418 In vivo CRISPR screening identifies Ptpn2 as a cancer immunotherapy target
by Robert T. Manguso & Hans W. Pope & Margaret D. Zimmer & Flavian D. Brown & Kathleen B. Yates & Brian C. Miller & Natalie B. Collins & Kevin Bi & Martin W. LaFleur & Vikram R. Juneja & Sarah A. Weiss & Jennifer Lo & David E. Fisher & Diana Miao & Eliezer Van Allen & David E. Root & Arlene H. Sharpe & John G. Doench & W. Nicholas Haining - 419-424 Maternal H3K27me3 controls DNA methylation-independent imprinting
by Azusa Inoue & Lan Jiang & Falong Lu & Tsukasa Suzuki & Yi Zhang - 425-427 Significant and variable linear polarization during the prompt optical flash of GRB 160625B
by E. Troja & V. M. Lipunov & C. G. Mundell & N. R. Butler & A. M. Watson & S. Kobayashi & S. B. Cenko & F. E. Marshall & R. Ricci & A. Fruchter & M. H. Wieringa & E. S. Gorbovskoy & V. Kornilov & A. Kutyrev & W. H. Lee & V. Toy & N. V. Tyurina & N. M. Budnev & D. A. H. Buckley & J. González & O. Gress & A. Horesh & M. I. Panasyuk & J. X. Prochaska & E. Ramirez-Ruiz & R. Rebolo Lopez & M. G. Richer & C. Román-Zúñiga & M. Serra-Ricart & V. Yurkov & N. Gehrels - 428-431 Neuromorphic computing with nanoscale spintronic oscillators
by Jacob Torrejon & Mathieu Riou & Flavio Abreu Araujo & Sumito Tsunegi & Guru Khalsa & Damien Querlioz & Paolo Bortolotti & Vincent Cros & Kay Yakushiji & Akio Fukushima & Hitoshi Kubota & Shinji Yuasa & Mark D. Stiles & Julie Grollier - 432-435 Spontaneous breaking of rotational symmetry in copper oxide superconductors
by J. Wu & A. T. Bollinger & X. He & I. Božović - 436-440 Synergy of synthesis, computation and NMR reveals correct baulamycin structures
by Jingjing Wu & Paula Lorenzo & Siying Zhong & Muhammad Ali & Craig P. Butts & Eddie L. Myers & Varinder K. Aggarwal - 441-444 Global forest loss disproportionately erodes biodiversity in intact landscapes
by Matthew G. Betts & Christopher Wolf & William J. Ripple & Ben Phalan & Kimberley A. Millers & Adam Duarte & Stuart H. M. Butchart & Taal Levi - 445-448 A novel mechanism for mechanosensory-based rheotaxis in larval zebrafish
by Pablo Oteiza & Iris Odstrcil & George Lauder & Ruben Portugues & Florian Engert - 449-452 Synaptic organization of visual space in primary visual cortex
by M. Florencia Iacaruso & Ioana T. Gasler & Sonja B. Hofer - 453-457 Dependency of a therapy-resistant state of cancer cells on a lipid peroxidase pathway
by Vasanthi S. Viswanathan & Matthew J. Ryan & Harshil D. Dhruv & Shubhroz Gill & Ossia M. Eichhoff & Brinton Seashore-Ludlow & Samuel D. Kaffenberger & John K. Eaton & Kenichi Shimada & Andrew J. Aguirre & Srinivas R. Viswanathan & Shrikanta Chattopadhyay & Pablo Tamayo & Wan Seok Yang & Matthew G. Rees & Sixun Chen & Zarko V. Boskovic & Sarah Javaid & Cherrie Huang & Xiaoyun Wu & Yuen-Yi Tseng & Elisabeth M. Roider & Dong Gao & James M. Cleary & Brian M. Wolpin & Jill P. Mesirov & Daniel A. Haber & Jeffrey A. Engelman & Jesse S. Boehm & Joanne D. Kotz & Cindy S. Hon & Yu Chen & William C. Hahn & Mitchell P. Levesque & John G. Doench & Michael E. Berens & Alykhan F. Shamji & Paul A. Clemons & Brent R. Stockwell & Stuart L. Schreiber - 458-462 Cysteine protease cathepsin B mediates radiation-induced bystander effects
by Yu Peng & Man Zhang & Lingjun Zheng & Qian Liang & Hanzeng Li & Jeng-Ting Chen & Hongyan Guo & Sawako Yoshina & Yu-Zen Chen & Xiang Zhao & Xiaoqi Wu & Bin Liu & Shohei Mitani & Jau-Song Yu & Ding Xue - 463-467 Unique roles for histone H3K9me states in RNAi and heritable silencing of transcription
by Gloria Jih & Nahid Iglesias & Mark A. Currie & Natarajan V. Bhanu & Joao A. Paulo & Steven P. Gygi & Benjamin A. Garcia & Danesh Moazed - 468-471 Crystal structures of agonist-bound human cannabinoid receptor CB1
by Tian Hua & Kiran Vemuri & Spyros P. Nikas & Robert B. Laprairie & Yiran Wu & Lu Qu & Mengchen Pu & Anisha Korde & Shan Jiang & Jo-Hao Ho & Gye Won Han & Kang Ding & Xuanxuan Li & Haiguang Liu & Michael A. Hanson & Suwen Zhao & Laura M. Bohn & Alexandros Makriyannis & Raymond C. Stevens & Zhi-Jie Liu - 472-475 The lysosomal potassium channel TMEM175 adopts a novel tetrameric architecture
by Changkeun Lee & Jiangtao Guo & Weizhong Zeng & Sunghoon Kim & Ji She & Chunlei Cang & Dejian Ren & Youxing Jiang - 476-476 Erratum: Structure of the Cpf1 endonuclease R-loop complex after target DNA cleavage
by Stefano Stella & Pablo Alcón & Guillermo Montoya - 476-476 Correction: Corrigendum: Splicing factor 1 modulates dietary restriction and TORC1 pathway longevity in C. elegans
by Caroline Heintz & Thomas K. Doktor & Anne Lanjuin & Caroline C. Escoubas & Yue Zhang & Heather J. Weir & Sneha Dutta & Carlos Giovanni Silva-García & Gitte H. Bruun & Ianessa Morantte & Gerta Hoxhaj & Brendan D. Manning & Brage S. Andresen & William B. Mair - 476-476 Correction: Corrigendum: Molecular mechanism for the regulation of yeast separase by securin
by Shukun Luo & Liang Tong - 477-479 How to hack the genome
by Jeffrey M. Perkel - 481-482 Lab etiquette: The perils of pet peeves
by Amber Dance - 483-483 Look for the leaders
by Toddi A. Steelman & Jeffrey J. McDonnell - 486-486 Good news
by Jack McDevitt
July 2017, Volume 547, Issue 7663
- 259-259 The DeepMind debacle demands dialogue on data
by Hetan Shah - 265-266 Satellite snafu masked true sea-level rise for decades
by Jeff Tollefson - 266-267 Female astronomers of colour face daunting discrimination
by Rachael Lallensack - 267-268 European Commission urges logging ban in ancient Białowieża Forest
by Quirin Schiermeier - 268-268 US lawmakers seek $1.1-billion boost for the NIH
by Lauren Morello - 269-269 Climate scientists flock to France’s call
by Declan Butler - 270-270 Engineered cell therapy for cancer gets thumbs up from FDA advisers
by Heidi Ledford - 272-274 The strange topology that is reshaping physics
by Davide Castelvecchi - 275-277 Solve Antarctica’s sea-ice puzzle
by John Turner & Josefino Comiso - 278-279 Environment: A journey on plastic seas
by Richard Thompson - 279-279 Books in brief
by Barbara Kiser - 280-280 History: Tracking down a doomed Arctic expedition
by Daniel Cressey - 281-281 No cost crisis for space telescope
by Thomas H. Zurbuchen - 281-281 Restrict bush fires used in animal hunts
by Mwazvita T. B. Dalu & Tatenda Dalu & Ryan J. Wasserman - 281-281 Paris neurosurgeon's map outwitted Nazis
by Pierre Bourdillon & Marc Lévêque & Caroline Apra - 284-285 Stellar palaeontology
by Ilya Mandel & Alison Farmer - 285-286 Early signs of human presence in Australia
by Curtis W. Marean - 287-288 Chemistry and physics happily wed
by Gregory A. Fiete - 288-290 Nervous crosstalk to make antibodies
by Hai Qi - 290-291 X-rays used to watch spins in 3D
by Peter Fischer - 291-292 Keeping it real to kill glioblastoma
by Paul A. Northcott - 293-297 Ribosomes are optimized for autocatalytic production
by Shlomi Reuveni & Måns Ehrenberg & Johan Paulsson - 298-305 Topological quantum chemistry
by Barry Bradlyn & L. Elcoro & Jennifer Cano & M. G. Vergniory & Zhijun Wang & C. Felser & M. I. Aroyo & B. Andrei Bernevig - 306-310 Human occupation of northern Australia by 65,000 years ago
by Chris Clarkson & Zenobia Jacobs & Ben Marwick & Richard Fullagar & Lynley Wallis & Mike Smith & Richard G. Roberts & Elspeth Hayes & Kelsey Lowe & Xavier Carah & S. Anna Florin & Jessica McNeil & Delyth Cox & Lee J. Arnold & Quan Hua & Jillian Huntley & Helen E. A. Brand & Tiina Manne & Andrew Fairbairn & James Shulmeister & Lindsey Lyle & Makiah Salinas & Mara Page & Kate Connell & Gayoung Park & Kasih Norman & Tessa Murphy & Colin Pardoe - 311-317 The whole-genome landscape of medulloblastoma subtypes
by Paul A. Northcott & Ivo Buchhalter & A. Sorana Morrissy & Volker Hovestadt & Joachim Weischenfeldt & Tobias Ehrenberger & Susanne Gröbner & Maia Segura-Wang & Thomas Zichner & Vasilisa A. Rudneva & Hans-Jörg Warnatz & Nikos Sidiropoulos & Aaron H. Phillips & Steven Schumacher & Kortine Kleinheinz & Sebastian M. Waszak & Serap Erkek & David T. W. Jones & Barbara C. Worst & Marcel Kool & Marc Zapatka & Natalie Jäger & Lukas Chavez & Barbara Hutter & Matthias Bieg & Nagarajan Paramasivam & Michael Heinold & Zuguang Gu & Naveed Ishaque & Christina Jäger-Schmidt & Charles D. Imbusch & Alke Jugold & Daniel Hübschmann & Thomas Risch & Vyacheslav Amstislavskiy & Francisco German Rodriguez Gonzalez & Ursula D. Weber & Stephan Wolf & Giles W. Robinson & Xin Zhou & Gang Wu & David Finkelstein & Yanling Liu & Florence M. G. Cavalli & Betty Luu & Vijay Ramaswamy & Xiaochong Wu & Jan Koster & Marina Ryzhova & Yoon-Jae Cho & Scott L. Pomeroy & Christel Herold-Mende & Martin Schuhmann & Martin Ebinger & Linda M. Liau & Jaume Mora & Roger E. McLendon & Nada Jabado & Toshihiro Kumabe & Eric Chuah & Yussanne Ma & Richard A. Moore & Andrew J. Mungall & Karen L. Mungall & Nina Thiessen & Kane Tse & Tina Wong & Steven J. M. Jones & Olaf Witt & Till Milde & Andreas Von Deimling & David Capper & Andrey Korshunov & Marie-Laure Yaspo & Richard Kriwacki & Amar Gajjar & Jinghui Zhang & Rameen Beroukhim & Ernest Fraenkel & Jan O. Korbel & Benedikt Brors & Matthias Schlesner & Roland Eils & Marco A. Marra & Stefan M. Pfister & Michael D. Taylor & Peter Lichter - 318-323 TFH-derived dopamine accelerates productive synapses in germinal centres
by Ilenia Papa & David Saliba & Maurilio Ponzoni & Sonia Bustamante & Pablo F. Canete & Paula Gonzalez-Figueroa & Hayley A. McNamara & Salvatore Valvo & Michele Grimbaldeston & Rebecca A. Sweet & Harpreet Vohra & Ian A. Cockburn & Michael Meyer-Hermann & Michael L. Dustin & Claudio Doglioni & Carola G. Vinuesa - 324-327 Experimental signatures of the mixed axial–gravitational anomaly in the Weyl semimetal NbP
by Johannes Gooth & Anna C. Niemann & Tobias Meng & Adolfo G. Grushin & Karl Landsteiner & Bernd Gotsmann & Fabian Menges & Marcus Schmidt & Chandra Shekhar & Vicky Süß & Ruben Hühne & Bernd Rellinghaus & Claudia Felser & Binghai Yan & Kornelius Nielsch - 328-331 Three-dimensional magnetization structures revealed with X-ray vector nanotomography
by Claire Donnelly & Manuel Guizar-Sicairos & Valerio Scagnoli & Sebastian Gliga & Mirko Holler & Jörg Raabe & Laura J. Heyderman - 332-335 Nitrogen reduction and functionalization by a multimetallic uranium nitride complex
by Marta Falcone & Lucile Chatelain & Rosario Scopelliti & Ivica Živković & Marinella Mazzanti - 336-339 Large-scale physical activity data reveal worldwide activity inequality
by Tim Althoff & Rok Sosič & Jennifer L. Hicks & Abby C. King & Scott L. Delp & Jure Leskovec - 340-344 Infant viewing of social scenes is under genetic control and is atypical in autism
by John N. Constantino & Stefanie Kennon-McGill & Claire Weichselbaum & Natasha Marrus & Alyzeh Haider & Anne L. Glowinski & Scott Gillespie & Cheryl Klaiman & Ami Klin & Warren Jones - 345-349 CRISPR–Cas encoding of a digital movie into the genomes of a population of living bacteria
by Seth L. Shipman & Jeff Nivala & Jeffrey D. Macklis & George M. Church - 350-354 Cholangiocytes act as facultative liver stem cells during impaired hepatocyte regeneration
by Alexander Raven & Wei-Yu Lu & Tak Yung Man & Sofia Ferreira-Gonzalez & Eoghan O’Duibhir & Benjamin J. Dwyer & John P. Thomson & Richard R. Meehan & Roman Bogorad & Victor Koteliansky & Yuri Kotelevtsev & Charles ffrench-Constant & Luke Boulter & Stuart J. Forbes - 355-359 Transcription elongation factors represent in vivo cancer dependencies in glioblastoma
by Tyler E. Miller & Brian B. Liau & Lisa C. Wallace & Andrew R. Morton & Qi Xie & Deobrat Dixit & Daniel C. Factor & Leo J. Y. Kim & James J. Morrow & Qiulian Wu & Stephen C. Mack & Christopher G. Hubert & Shawn M. Gillespie & William A. Flavahan & Thomas Hoffmann & Rohit Thummalapalli & Michael T. Hemann & Patrick J. Paddison & Craig M. Horbinski & Johannes Zuber & Peter C. Scacheri & Bradley E. Bernstein & Paul J. Tesar & Jeremy N. Rich - 360-363 Open and closed structures reveal allostery and pliability in the HIV-1 envelope spike
by Gabriel Ozorowski & Jesper Pallesen & Natalia de Val & Dmitry Lyumkis & Christopher A. Cottrell & Jonathan L. Torres & Jeffrey Copps & Robyn L. Stanfield & Albert Cupo & Pavel Pugach & John P. Moore & Ian A. Wilson & Andrew B. Ward - 364-368 K2P2.1 (TREK-1)–activator complexes reveal a cryptic selectivity filter binding site
by Marco Lolicato & Cristina Arrigoni & Takahiro Mori & Yoko Sekioka & Clifford Bryant & Kimberly A. Clark & Daniel L. Minor - 369-371 Enterprise: Game on
by Roberta Kwok - 371-371 Turning point: Soft-skills sculptor
by Virginia Gewin - 374-374 Catalogue of Items in the Chess Exhibition at the Humanities Museum, Pre-Enlightenment Wing
by Alex Shvartsman
July 2017, Volume 547, Issue 7662
- 9-10 Conflicting evidence for ferroelectricity
by Gabriele D’Avino & Manuel Souto & Matteo Masino & Jonas K. H. Fischer & Imma Ratera & Xavier Fontrodona & Gianluca Giovannetti & Matthieu J. Verstraete & Anna Painelli & Peter Lunkenheimer & Jaume Veciana & Alberto Girlando - 14-15 Tayi et al. reply
by Alok S. Tayi & Alexander K. Shveyd & Andrew C.-H. Sue & Jodi M. Szarko & Brian S. Rolczynski & Dennis Cao & T. Jackson Kennedy & Amy A. Sarjeant & Charlotte L. Stern & Walter F. Paxton & Wei Wu & Sanjeev K. Dey & Albert C. Fahrenbach & Jeffrey R. Guest & Hooman Mohseni & Lin X. Chen & Kang L. Wang & J. Fraser Stoddart & Samuel I. Stupp - 16-17 Overestimate of committed warming
by Gavin A. Schmidt & Jeff Severinghaus & Ayako Abe-Ouchi & Richard B. Alley & Wallace Broecker & Ed Brook & David Etheridge & Kenji Kawamura & Ralph F. Keeling & Margaret Leinen & Kate Marvel & Thomas F. Stocker - 17-18 Snyder replies
by Carolyn W. Snyder - 139-139 Kill the myth of the miracle machine
by Daniel Sarewitz - 145-146 White House’s dwindling science office leaves major research programmes in limbo
by Sara Reardon - 146-147 Why planetary scientists want better fake space dirt
by Alexandra Witze - 147-147 Massive database of 182,000 leaves is helping predict plants' family trees
by Heidi Ledford - 148-148 Tricks to mute quantum noise aid hunt for gravitational waves
by Elizabeth Gibney - 149-149 Ancient-genome studies grapple with Africa’s past
by Ewen Callaway - 150-152 How poverty affects the brain
by Carina Storrs - 153-155 Stop Alzheimer’s before it starts
by Eric McDade & Randall J. Bateman - 156-158 Witness gravity’s quantum side in the lab
by Chiara Marletto & Vlatko Vedral - 159-159 Information technology: A digital genius at play
by Vint Cerf - 160-161 History: Science lessons from the Gulag
by Asif Siddiqi - 161-161 Books in brief
by Barbara Kiser - 162-162 Switch it off on eclipse day
by Steve Elgar - 162-162 Manage chemicals and waste globally
by Quanyin Tan & Jinhui Li - 162-162 Taxonomy: refine rather than stabilize
by Fenton P. D. Cotterill & Colin P. Groves & Peter J. Taylor - 162-162 Philanthropic risks can hit home runs
by Melissa L. Stevens - 162-162 CRISPR book review — Doudna responds
by Jennifer Doudna - 164-165 Sensing past the quantum limit
by Christopher G. Baker & Warwick P. Bowen - 165-167 Precision T-cell therapy targets tumours
by Cornelis J. M. Melief - 167-168 Arctic plants take up mercury vapour
by William Shotyk - 168-169 A liquid reservoir for silent chromatin
by Adam Klosin & Anthony A. Hyman - 170-171 Taming tangled tau
by David S. Eisenberg & Michael R. Sawaya - 171-172 Bile ducts regenerated
by Ludi Zhang & Lijian Hui - 173-178 Fine-mapping inflammatory bowel disease loci to single-variant resolution
by Hailiang Huang & Ming Fang & Luke Jostins & Maša Umićević Mirkov & Gabrielle Boucher & Carl A. Anderson & Vibeke Andersen & Isabelle Cleynen & Adrian Cortes & François Crins & Mauro D’Amato & Valérie Deffontaine & Julia Dmitrieva & Elisa Docampo & Mahmoud Elansary & Kyle Kai-How Farh & Andre Franke & Ann-Stephan Gori & Philippe Goyette & Jonas Halfvarson & Talin Haritunians & Jo Knight & Ian C. Lawrance & Charlie W. Lees & Edouard Louis & Rob Mariman & Theo Meuwissen & Myriam Mni & Yukihide Momozawa & Miles Parkes & Sarah L. Spain & Emilie Théâtre & Gosia Trynka & Jack Satsangi & Suzanne van Sommeren & Severine Vermeire & Ramnik J. Xavier & Rinse K. Weersma & Richard H. Duerr & Christopher G. Mathew & John D. Rioux & Dermot P. B. McGovern & Judy H. Cho & Michel Georges & Mark J. Daly & Jeffrey C. Barrett - 179-184 The extracellular matrix protein agrin promotes heart regeneration in mice
by Elad Bassat & Yara Eid Mutlak & Alex Genzelinakh & Ilya Y. Shadrin & Kfir Baruch Umansky & Oren Yifa & David Kain & Dana Rajchman & John Leach & Daria Riabov Bassat & Yael Udi & Rachel Sarig & Irit Sagi & James F. Martin & Nenad Bursac & Shenhav Cohen & Eldad Tzahor - 185-190 Cryo-EM structures of tau filaments from Alzheimer’s disease
by Anthony W. P. Fitzpatrick & Benjamin Falcon & Shaoda He & Alexey G. Murzin & Garib Murshudov & Holly J. Garringer & R. Anthony Crowther & Bernardino Ghetti & Michel Goedert & Sjors H. W. Scheres - 191-195 Quantum back-action-evading measurement of motion in a negative mass reference frame
by Christoffer B. Møller & Rodrigo A. Thomas & Georgios Vasilakis & Emil Zeuthen & Yeghishe Tsaturyan & Mikhail Balabas & Kasper Jensen & Albert Schliesser & Klemens Hammerer & Eugene S. Polzik - 196-200 Catalytic allylic oxidation of internal alkenes to a multifunctional chiral building block
by Liela Bayeh & Phong Q. Le & Uttam K. Tambar - 201-204 Tundra uptake of atmospheric elemental mercury drives Arctic mercury pollution
by Daniel Obrist & Yannick Agnan & Martin Jiskra & Christine L. Olson & Dominique P. Colegrove & Jacques Hueber & Christopher W. Moore & Jeroen E. Sonke & Detlev Helmig - 205-208 The pyrite-type high-pressure form of FeOOH
by Masayuki Nishi & Yasuhiro Kuwayama & Jun Tsuchiya & Taku Tsuchiya - 209-212 Pre-oral gut contributes to facial structures in non-teleost fishes
by Martin Minarik & Jan Stundl & Peter Fabian & David Jandzik & Brian D. Metscher & Martin Psenicka & David Gela & Adriana Osorio-Pérez & Lenin Arias-Rodriguez & Ivan Horácek & Robert Cerny - 213-216 Nutrient sensing modulates malaria parasite virulence
by Liliana Mancio-Silva & Ksenija Slavic & Margarida T. Grilo Ruivo & Ana Rita Grosso & Katarzyna K. Modrzynska & Iset Medina Vera & Joana Sales-Dias & Ana Rita Gomes & Cameron Ross MacPherson & Pierre Crozet & Mattia Adamo & Elena Baena-Gonzalez & Rita Tewari & Manuel Llinás & Oliver Billker & Maria M. Mota - 217-221 An immunogenic personal neoantigen vaccine for patients with melanoma
by Patrick A. Ott & Zhuting Hu & Derin B. Keskin & Sachet A. Shukla & Jing Sun & David J. Bozym & Wandi Zhang & Adrienne Luoma & Anita Giobbie-Hurder & Lauren Peter & Christina Chen & Oriol Olive & Todd A. Carter & Shuqiang Li & David J. Lieb & Thomas Eisenhaure & Evisa Gjini & Jonathan Stevens & William J. Lane & Indu Javeri & Kaliappanadar Nellaiappan & Andres M. Salazar & Heather Daley & Michael Seaman & Elizabeth I. Buchbinder & Charles H. Yoon & Maegan Harden & Niall Lennon & Stacey Gabriel & Scott J. Rodig & Dan H. Barouch & Jon C. Aster & Gad Getz & Kai Wucherpfennig & Donna Neuberg & Jerome Ritz & Eric S. Lander & Edward F. Fritsch & Nir Hacohen & Catherine J. Wu - 222-226 Personalized RNA mutanome vaccines mobilize poly-specific therapeutic immunity against cancer
by Ugur Sahin & Evelyna Derhovanessian & Matthias Miller & Björn-Philipp Kloke & Petra Simon & Martin Löwer & Valesca Bukur & Arbel D. Tadmor & Ulrich Luxemburger & Barbara Schrörs & Tana Omokoko & Mathias Vormehr & Christian Albrecht & Anna Paruzynski & Andreas N. Kuhn & Janina Buck & Sandra Heesch & Katharina H. Schreeb & Felicitas Müller & Inga Ortseifer & Isabel Vogler & Eva Godehardt & Sebastian Attig & Richard Rae & Andrea Breitkreuz & Claudia Tolliver & Martin Suchan & Goran Martic & Alexander Hohberger & Patrick Sorn & Jan Diekmann & Janko Ciesla & Olga Waksmann & Alexandra-Kemmer Brück & Meike Witt & Martina Zillgen & Andree Rothermel & Barbara Kasemann & David Langer & Stefanie Bolte & Mustafa Diken & Sebastian Kreiter & Romina Nemecek & Christoffer Gebhardt & Stephan Grabbe & Christoph Höller & Jochen Utikal & Christoph Huber & Carmen Loquai & Özlem Türeci - 227-231 Dystrophin–glycoprotein complex sequesters Yap to inhibit cardiomyocyte proliferation
by Yuka Morikawa & Todd Heallen & John Leach & Yang Xiao & James F. Martin - 232-235 Allelic reprogramming of 3D chromatin architecture during early mammalian development
by Zhenhai Du & Hui Zheng & Bo Huang & Rui Ma & Jingyi Wu & Xianglin Zhang & Jing He & Yunlong Xiang & Qiujun Wang & Yuanyuan Li & Jing Ma & Xu Zhang & Ke Zhang & Yang Wang & Michael Q. Zhang & Juntao Gao & Jesse R. Dixon & Xiaowo Wang & Jianyang Zeng & Wei Xie - 236-240 Liquid droplet formation by HP1α suggests a role for phase separation in heterochromatin
by Adam G. Larson & Daniel Elnatan & Madeline M. Keenen & Michael J. Trnka & Jonathan B. Johnston & Alma L. Burlingame & David A. Agard & Sy Redding & Geeta J. Narlikar - 241-245 Phase separation drives heterochromatin domain formation
by Amy R. Strom & Alexander V. Emelyanov & Mustafa Mir & Dmitry V. Fyodorov & Xavier Darzacq & Gary H. Karpen - 246-246 Retraction Note: Oncogenic activity of Cdc6 through repression of the INK4/ARF locus
by Susana Gonzalez & Peter Klatt & Sonia Delgado & Esther Conde & Fernando Lopez-Rios & Montserrat Sanchez-Cespedes & Juan Mendez & Francisco Antequera & Manuel Serrano - 246-246 Correction: Corrigendum: Mineral supply for sustainable development requires resource governance
by Saleem H. Ali & Damien Giurco & Nicholas Arndt & Edmund Nickless & Graham Brown & Alecos Demetriades & Ray Durrheim & Maria Amélia Enriquez & Judith Kinnaird & Anna Littleboy & Lawrence D. Meinert & Roland Oberhänsli & Janet Salem & Richard Schodde & Gabi Schneider & Olivier Vidal & Natalia Yakovleva - 247-249 Housing: A home on a budget
by Chris Woolston - 249-249 Turning point: Tenacious chemist
by Virginia Gewin - 252-252 Legs-11
by Hugh Cartwright
July 2017, Volume 547, Issue 7661
- 1-3 Upholding a role for EMT in breast cancer metastasis
by Xin Ye & Thomas Brabletz & Yibin Kang & Gregory D. Longmore & M. Angela Nieto & Ben Z. Stanger & Jing Yang & Robert A. Weinberg - 5-6 Fischer et al. reply
by Kari R. Fischer & Nasser K. Altorki & Vivek Mittal & Dingcheng Gao - 7-7 Our obsession with eminence warps research
by Simine Vazire - 7-8 Upholding a role for EMT in pancreatic cancer metastasis
by Nicole M. Aiello & Thomas Brabletz & Yibin Kang & M. Angela Nieto & Robert A. Weinberg & Ben Z. Stanger - 13-14 Google spin-off deploys wearable electronics for huge health study
by Amy Maxmen - 14-15 Ebola outbreak in Africa ends — but gaps in public health leave region vulnerable
by Erika Check Hayden - 15-15 Has Harry Potter mania cursed Indonesia's owls?
by Inga Vesper - 16-16 Qatar blockade hits helium supply
by Declan Butler - 17-17 Europe’s next big science-funding programme urged to double its budget
by Alison Abbott - 20-22 The trickiest family tree in biology
by Ewen Callaway - 27-29 Immunology, one cell at a time
by Amir Giladi & Ido Amit - 30-31 Cybersecurity: The cold war online
by Steven Aftergood - 31-31 Books in brief
by Barbara Kiser - 32-32 Japan disregards whaling review again
by Phillip J. Clapham - 32-32 Stop ruining Turkey's geological heritage
by A. M. Celal Şengör & Nalan Lom - 32-32 Defend real science in the Balkans
by Jelena Kalinić - 32-32 AI zooms in on highly influential citations
by Oren Etzioni - 32-32 Flagging gender bias doesn't always work
by Greta Faccio - 34-35 Continuous chromatin changes
by Robert A. Beagrie & Ana Pombo - 35-36 Ice-sheet history revealed by fossils
by Jennifer Hertzberg - 36-38 The patterns of T-cell target recognition
by Sai T. Reddy - 38-39 3D integration advances computing
by Sherief Reda - 40-41 Less is more in the hunt for driver mutations
by Sushant Kumar & Mark Gerstein - 41-42 Stellar siblings grow closer with age
by Aaron M. Geller - 43-48 West Antarctic Ice Sheet retreat driven by Holocene warm water incursions
by Claus-Dieter Hillenbrand & James A. Smith & David A. Hodell & Mervyn Greaves & Christopher R. Poole & Sev Kender & Mark Williams & Thorbjørn Joest Andersen & Patrycja E. Jernas & Henry Elderfield & Johann P. Klages & Stephen J. Roberts & Karsten Gohl & Robert D. Larter & Gerhard Kuhn - 49-54 Climate change drives expansion of Antarctic ice-free habitat
by Jasmine R. Lee & Ben Raymond & Thomas J. Bracegirdle & Iadine Chadès & Richard A. Fuller & Justine D. Shaw & Aleks Terauds - 55-60 Recurrent and functional regulatory mutations in breast cancer
by Esther Rheinbay & Prasanna Parasuraman & Jonna Grimsby & Grace Tiao & Jesse M. Engreitz & Jaegil Kim & Michael S. Lawrence & Amaro Taylor-Weiner & Sergio Rodriguez-Cuevas & Mara Rosenberg & Julian Hess & Chip Stewart & Yosef E. Maruvka & Petar Stojanov & Maria L. Cortes & Sara Seepo & Carrie Cibulskis & Adam Tracy & Trevor J. Pugh & Jesse Lee & Zongli Zheng & Leif W. Ellisen & A. John Iafrate & Jesse S. Boehm & Stacey B. Gabriel & Matthew Meyerson & Todd R. Golub & Jose Baselga & Alfredo Hidalgo-Miranda & Toshi Shioda & Andre Bernards & Eric S. Lander & Gad Getz - 61-67 Cell-cycle dynamics of chromosomal organization at single-cell resolution
by Takashi Nagano & Yaniv Lubling & Csilla Várnai & Carmel Dudley & Wing Leung & Yael Baran & Netta Mendelson Cohen & Steven Wingett & Peter Fraser & Amos Tanay - 68-73 Single-molecule analysis of ligand efficacy in β2AR–G-protein activation
by G. Glenn Gregorio & Matthieu Masureel & Daniel Hilger & Daniel S. Terry & Manuel Juette & Hong Zhao & Zhou Zhou & Jose Manuel Perez-Aguilar & Maria Hauge & Signe Mathiasen & Jonathan A. Javitch & Harel Weinstein & Brian K. Kobilka & Scott C. Blanchard - 74-78 Three-dimensional integration of nanotechnologies for computing and data storage on a single chip
by Max M. Shulaker & Gage Hills & Rebecca S. Park & Roger T. Howe & Krishna Saraswat & H.-S. Philip Wong & Subhasish Mitra - 79-83 Selective sp3 C–H alkylation via polarity-match-based cross-coupling
by Chip Le & Yufan Liang & Ryan W. Evans & Ximing Li & David W. C. MacMillan - 84-88 Episodic kinematics in continental rifts modulated by changes in mantle melt fraction
by Simon Lamb & James D. P. Moore & Euan Smith & Tim Stern - 89-93 Quantifiable predictive features define epitope-specific T cell receptor repertoires
by Pradyot Dash & Andrew J. Fiore-Gartland & Tomer Hertz & George C. Wang & Shalini Sharma & Aisha Souquette & Jeremy Chase Crawford & E. Bridie Clemens & Thi H. O. Nguyen & Katherine Kedzierska & Nicole L. La Gruta & Philip Bradley & Paul G. Thomas - 94-98 Identifying specificity groups in the T cell receptor repertoire
by Jacob Glanville & Huang Huang & Allison Nau & Olivia Hatton & Lisa E. Wagar & Florian Rubelt & Xuhuai Ji & Arnold Han & Sheri M. Krams & Christina Pettus & Nikhil Haas & Cecilia S. Lindestam Arlehamn & Alessandro Sette & Scott D. Boyd & Thomas J. Scriba & Olivia M. Martinez & Mark M. Davis - 99-103 Chemotherapy drugs induce pyroptosis through caspase-3 cleavage of a gasdermin
by Yupeng Wang & Wenqing Gao & Xuyan Shi & Jingjin Ding & Wang Liu & Huabin He & Kun Wang & Feng Shao - 104-108 Tracing the origins of relapse in acute myeloid leukaemia to stem cells
by Liran I. Shlush & Amanda Mitchell & Lawrence Heisler & Sagi Abelson & Stanley W. K. Ng & Aaron Trotman-Grant & Jessie J. F. Medeiros & Abilasha Rao-Bhatia & Ivana Jaciw-Zurakowsky & Rene Marke & Jessica L. McLeod & Monica Doedens & Gary Bader & Veronique Voisin & ChangJiang Xu & John D. McPherson & Thomas J. Hudson & Jean C. Y. Wang & Mark D. Minden & John E. Dick - 109-113 mTORC1-dependent AMD1 regulation sustains polyamine metabolism in prostate cancer
by Amaia Zabala-Letona & Amaia Arruabarrena-Aristorena & Natalia Martín-Martín & Sonia Fernandez-Ruiz & James D. Sutherland & Michelle Clasquin & Julen Tomas-Cortazar & Jose Jimenez & Ines Torres & Phong Quang & Pilar Ximenez-Embun & Ruzica Bago & Aitziber Ugalde-Olano & Ana Loizaga-Iriarte & Isabel Lacasa-Viscasillas & Miguel Unda & Verónica Torrano & Diana Cabrera & Sebastiaan M. van Liempd & Ylenia Cendon & Elena Castro & Stuart Murray & Ajinkya Revandkar & Andrea Alimonti & Yinan Zhang & Amelia Barnett & Gina Lein & David Pirman & Ana R. Cortazar & Leire Arreal & Ludmila Prudkin & Ianire Astobiza & Lorea Valcarcel-Jimenez & Patricia Zuñiga-García & Itziar Fernandez-Dominguez & Marco Piva & Alfredo Caro-Maldonado & Pilar Sánchez-Mosquera & Mireia Castillo-Martín & Violeta Serra & Naiara Beraza & Antonio Gentilella & George Thomas & Mikel Azkargorta & Felix Elortza & Rosa Farràs & David Olmos & Alejo Efeyan & Juan Anguita & Javier Muñoz & Juan M. Falcón-Pérez & Rosa Barrio & Teresa Macarulla & Jose M. Mato & Maria L. Martinez-Chantar & Carlos Cordon-Cardo & Ana M. Aransay & Kevin Marks & José Baselga & Josep Tabernero & Paolo Nuciforo & Brendan D. Manning & Katya Marjon & Arkaitz Carracedo - 114-117 RNase III nucleases from diverse kingdoms serve as antiviral effectors
by Lauren C. Aguado & Sonja Schmid & Jared May & Leah R. Sabin & Maryline Panis & Daniel Blanco-Melo & Jaehee V. Shim & David Sachs & Sara Cherry & Anne E. Simon & Jean-Pierre Levraud & Benjamin R. tenOever - 118-122 Electron cryo-microscopy structure of the mechanotransduction channel NOMPC
by Peng Jin & David Bulkley & Yanmeng Guo & Wei Zhang & Zhenhao Guo & Walter Huynh & Shenping Wu & Shan Meltzer & Tong Cheng & Lily Yeh Jan & Yuh-Nung Jan & Yifan Cheng - 123-124 Addendum: Immune clearance of highly pathogenic SIV infection
by Scott G. Hansen & Michael Piatak & Abigail B. Ventura & Colette M. Hughes & Roxanne M. Gilbride & Julia C. Ford & Kelli Oswald & Rebecca Shoemaker & Yuan Li & Matthew S. Lewis & Awbrey N. Gilliam & Guangwu Xu & Nathan Whizin & Benjamin J. Burwitz & Shannon L. Planer & John M. Turner & Alfred W. Legasse & Michael K. Axthelm & Jay A. Nelson & Klaus Früh & Jonah B. Sacha & Jacob D. Estes & Brandon F. Keele & Paul T. Edlefsen & Jeffrey D. Lifson & Louis J. Picker - 125-126 Single-cell sequencing made simple
by Jeffrey M. Perkel - 127-129 Glycobiology: Sweet success
by Esther Landhuis - 129-129 Turning point: Single-cell mapper
by Virginia Gewin - 132-132 The ghost in the machine
by Anna Novitzky
June 2017, Volume 546, Issue 7660
- 6-7 Contesting the evidence for limited human lifespan
by Nicholas J. L. Brown & Casper J. Albers & Stuart J. Ritchie - 7-7 Dong et al. reply
by Xiao Dong & Brandon Milholland & Jan Vijg - 8-9 Many possible maximum lifespan trajectories
by Bryan G. Hughes & Siegfried Hekimi - 9-10 Dong et al. reply
by Xiao Dong & Brandon Milholland & Jan Vijg - 11-12 Is there evidence for a limit to human lifespan?
by Maarten P. Rozing & Thomas B. L. Kirkwood & Rudi G. J. Westendorp - 12-12 Dong et al. reply
by Xiao Dong & Brandon Milholland & Jan Vijg - 13-14 Questionable evidence for a limit to human lifespan
by Adam Lenart & James W. Vaupel - 14-15 Dong et al. reply
by Xiao Dong & Brandon Milholland & Jan Vijg - 16-17 Maximum human lifespan may increase to 125 years
by Joop de Beer & Anastasios Bardoutsos & Fanny Janssen - 21-21 Dong et al. reply
by Xiao Dong & Brandon Milholland & Jan Vijg - 577-577 Let science be a springboard for politics
by James Martin - 583-584 Success of gravity-wave satellite paves way for three-craft mission
by Davide Castelvecchi - 584-585 Scientists in limbo as US Supreme Court allows modified travel ban
by Sara Reardon - 585-586 Overlooked water loss in plants could throw off climate models
by Heidi Ledford