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Content
July 2017, Volume 547, Issue 7664
- 472-475 The lysosomal potassium channel TMEM175 adopts a novel tetrameric architecture
by Changkeun Lee & Jiangtao Guo & Weizhong Zeng & Sunghoon Kim & Ji She & Chunlei Cang & Dejian Ren & Youxing Jiang - 476-476 Erratum: Structure of the Cpf1 endonuclease R-loop complex after target DNA cleavage
by Stefano Stella & Pablo Alcón & Guillermo Montoya - 476-476 Correction: Corrigendum: Splicing factor 1 modulates dietary restriction and TORC1 pathway longevity in C. elegans
by Caroline Heintz & Thomas K. Doktor & Anne Lanjuin & Caroline C. Escoubas & Yue Zhang & Heather J. Weir & Sneha Dutta & Carlos Giovanni Silva-García & Gitte H. Bruun & Ianessa Morantte & Gerta Hoxhaj & Brendan D. Manning & Brage S. Andresen & William B. Mair - 476-476 Correction: Corrigendum: Molecular mechanism for the regulation of yeast separase by securin
by Shukun Luo & Liang Tong - 477-479 How to hack the genome
by Jeffrey M. Perkel - 481-482 Lab etiquette: The perils of pet peeves
by Amber Dance - 483-483 Look for the leaders
by Toddi A. Steelman & Jeffrey J. McDonnell - 486-486 Good news
by Jack McDevitt
July 2017, Volume 547, Issue 7663
- 259-259 The DeepMind debacle demands dialogue on data
by Hetan Shah - 265-266 Satellite snafu masked true sea-level rise for decades
by Jeff Tollefson - 266-267 Female astronomers of colour face daunting discrimination
by Rachael Lallensack - 267-268 European Commission urges logging ban in ancient Białowieża Forest
by Quirin Schiermeier - 268-268 US lawmakers seek $1.1-billion boost for the NIH
by Lauren Morello - 269-269 Climate scientists flock to France’s call
by Declan Butler - 270-270 Engineered cell therapy for cancer gets thumbs up from FDA advisers
by Heidi Ledford - 272-274 The strange topology that is reshaping physics
by Davide Castelvecchi - 275-277 Solve Antarctica’s sea-ice puzzle
by John Turner & Josefino Comiso - 278-279 Environment: A journey on plastic seas
by Richard Thompson - 279-279 Books in brief
by Barbara Kiser - 280-280 History: Tracking down a doomed Arctic expedition
by Daniel Cressey - 281-281 No cost crisis for space telescope
by Thomas H. Zurbuchen - 281-281 Restrict bush fires used in animal hunts
by Mwazvita T. B. Dalu & Tatenda Dalu & Ryan J. Wasserman - 281-281 Paris neurosurgeon's map outwitted Nazis
by Pierre Bourdillon & Marc Lévêque & Caroline Apra - 284-285 Stellar palaeontology
by Ilya Mandel & Alison Farmer - 285-286 Early signs of human presence in Australia
by Curtis W. Marean - 287-288 Chemistry and physics happily wed
by Gregory A. Fiete - 288-290 Nervous crosstalk to make antibodies
by Hai Qi - 290-291 X-rays used to watch spins in 3D
by Peter Fischer - 291-292 Keeping it real to kill glioblastoma
by Paul A. Northcott - 293-297 Ribosomes are optimized for autocatalytic production
by Shlomi Reuveni & Måns Ehrenberg & Johan Paulsson - 298-305 Topological quantum chemistry
by Barry Bradlyn & L. Elcoro & Jennifer Cano & M. G. Vergniory & Zhijun Wang & C. Felser & M. I. Aroyo & B. Andrei Bernevig - 306-310 Human occupation of northern Australia by 65,000 years ago
by Chris Clarkson & Zenobia Jacobs & Ben Marwick & Richard Fullagar & Lynley Wallis & Mike Smith & Richard G. Roberts & Elspeth Hayes & Kelsey Lowe & Xavier Carah & S. Anna Florin & Jessica McNeil & Delyth Cox & Lee J. Arnold & Quan Hua & Jillian Huntley & Helen E. A. Brand & Tiina Manne & Andrew Fairbairn & James Shulmeister & Lindsey Lyle & Makiah Salinas & Mara Page & Kate Connell & Gayoung Park & Kasih Norman & Tessa Murphy & Colin Pardoe - 311-317 The whole-genome landscape of medulloblastoma subtypes
by Paul A. Northcott & Ivo Buchhalter & A. Sorana Morrissy & Volker Hovestadt & Joachim Weischenfeldt & Tobias Ehrenberger & Susanne Gröbner & Maia Segura-Wang & Thomas Zichner & Vasilisa A. Rudneva & Hans-Jörg Warnatz & Nikos Sidiropoulos & Aaron H. Phillips & Steven Schumacher & Kortine Kleinheinz & Sebastian M. Waszak & Serap Erkek & David T. W. Jones & Barbara C. Worst & Marcel Kool & Marc Zapatka & Natalie Jäger & Lukas Chavez & Barbara Hutter & Matthias Bieg & Nagarajan Paramasivam & Michael Heinold & Zuguang Gu & Naveed Ishaque & Christina Jäger-Schmidt & Charles D. Imbusch & Alke Jugold & Daniel Hübschmann & Thomas Risch & Vyacheslav Amstislavskiy & Francisco German Rodriguez Gonzalez & Ursula D. Weber & Stephan Wolf & Giles W. Robinson & Xin Zhou & Gang Wu & David Finkelstein & Yanling Liu & Florence M. G. Cavalli & Betty Luu & Vijay Ramaswamy & Xiaochong Wu & Jan Koster & Marina Ryzhova & Yoon-Jae Cho & Scott L. Pomeroy & Christel Herold-Mende & Martin Schuhmann & Martin Ebinger & Linda M. Liau & Jaume Mora & Roger E. McLendon & Nada Jabado & Toshihiro Kumabe & Eric Chuah & Yussanne Ma & Richard A. Moore & Andrew J. Mungall & Karen L. Mungall & Nina Thiessen & Kane Tse & Tina Wong & Steven J. M. Jones & Olaf Witt & Till Milde & Andreas Von Deimling & David Capper & Andrey Korshunov & Marie-Laure Yaspo & Richard Kriwacki & Amar Gajjar & Jinghui Zhang & Rameen Beroukhim & Ernest Fraenkel & Jan O. Korbel & Benedikt Brors & Matthias Schlesner & Roland Eils & Marco A. Marra & Stefan M. Pfister & Michael D. Taylor & Peter Lichter - 318-323 TFH-derived dopamine accelerates productive synapses in germinal centres
by Ilenia Papa & David Saliba & Maurilio Ponzoni & Sonia Bustamante & Pablo F. Canete & Paula Gonzalez-Figueroa & Hayley A. McNamara & Salvatore Valvo & Michele Grimbaldeston & Rebecca A. Sweet & Harpreet Vohra & Ian A. Cockburn & Michael Meyer-Hermann & Michael L. Dustin & Claudio Doglioni & Carola G. Vinuesa - 324-327 Experimental signatures of the mixed axial–gravitational anomaly in the Weyl semimetal NbP
by Johannes Gooth & Anna C. Niemann & Tobias Meng & Adolfo G. Grushin & Karl Landsteiner & Bernd Gotsmann & Fabian Menges & Marcus Schmidt & Chandra Shekhar & Vicky Süß & Ruben Hühne & Bernd Rellinghaus & Claudia Felser & Binghai Yan & Kornelius Nielsch - 328-331 Three-dimensional magnetization structures revealed with X-ray vector nanotomography
by Claire Donnelly & Manuel Guizar-Sicairos & Valerio Scagnoli & Sebastian Gliga & Mirko Holler & Jörg Raabe & Laura J. Heyderman - 332-335 Nitrogen reduction and functionalization by a multimetallic uranium nitride complex
by Marta Falcone & Lucile Chatelain & Rosario Scopelliti & Ivica Živković & Marinella Mazzanti - 336-339 Large-scale physical activity data reveal worldwide activity inequality
by Tim Althoff & Rok Sosič & Jennifer L. Hicks & Abby C. King & Scott L. Delp & Jure Leskovec - 340-344 Infant viewing of social scenes is under genetic control and is atypical in autism
by John N. Constantino & Stefanie Kennon-McGill & Claire Weichselbaum & Natasha Marrus & Alyzeh Haider & Anne L. Glowinski & Scott Gillespie & Cheryl Klaiman & Ami Klin & Warren Jones - 345-349 CRISPR–Cas encoding of a digital movie into the genomes of a population of living bacteria
by Seth L. Shipman & Jeff Nivala & Jeffrey D. Macklis & George M. Church - 350-354 Cholangiocytes act as facultative liver stem cells during impaired hepatocyte regeneration
by Alexander Raven & Wei-Yu Lu & Tak Yung Man & Sofia Ferreira-Gonzalez & Eoghan O’Duibhir & Benjamin J. Dwyer & John P. Thomson & Richard R. Meehan & Roman Bogorad & Victor Koteliansky & Yuri Kotelevtsev & Charles ffrench-Constant & Luke Boulter & Stuart J. Forbes - 355-359 Transcription elongation factors represent in vivo cancer dependencies in glioblastoma
by Tyler E. Miller & Brian B. Liau & Lisa C. Wallace & Andrew R. Morton & Qi Xie & Deobrat Dixit & Daniel C. Factor & Leo J. Y. Kim & James J. Morrow & Qiulian Wu & Stephen C. Mack & Christopher G. Hubert & Shawn M. Gillespie & William A. Flavahan & Thomas Hoffmann & Rohit Thummalapalli & Michael T. Hemann & Patrick J. Paddison & Craig M. Horbinski & Johannes Zuber & Peter C. Scacheri & Bradley E. Bernstein & Paul J. Tesar & Jeremy N. Rich - 360-363 Open and closed structures reveal allostery and pliability in the HIV-1 envelope spike
by Gabriel Ozorowski & Jesper Pallesen & Natalia de Val & Dmitry Lyumkis & Christopher A. Cottrell & Jonathan L. Torres & Jeffrey Copps & Robyn L. Stanfield & Albert Cupo & Pavel Pugach & John P. Moore & Ian A. Wilson & Andrew B. Ward - 364-368 K2P2.1 (TREK-1)–activator complexes reveal a cryptic selectivity filter binding site
by Marco Lolicato & Cristina Arrigoni & Takahiro Mori & Yoko Sekioka & Clifford Bryant & Kimberly A. Clark & Daniel L. Minor - 369-371 Enterprise: Game on
by Roberta Kwok - 371-371 Turning point: Soft-skills sculptor
by Virginia Gewin - 374-374 Catalogue of Items in the Chess Exhibition at the Humanities Museum, Pre-Enlightenment Wing
by Alex Shvartsman
July 2017, Volume 547, Issue 7662
- 9-10 Conflicting evidence for ferroelectricity
by Gabriele D’Avino & Manuel Souto & Matteo Masino & Jonas K. H. Fischer & Imma Ratera & Xavier Fontrodona & Gianluca Giovannetti & Matthieu J. Verstraete & Anna Painelli & Peter Lunkenheimer & Jaume Veciana & Alberto Girlando - 14-15 Tayi et al. reply
by Alok S. Tayi & Alexander K. Shveyd & Andrew C.-H. Sue & Jodi M. Szarko & Brian S. Rolczynski & Dennis Cao & T. Jackson Kennedy & Amy A. Sarjeant & Charlotte L. Stern & Walter F. Paxton & Wei Wu & Sanjeev K. Dey & Albert C. Fahrenbach & Jeffrey R. Guest & Hooman Mohseni & Lin X. Chen & Kang L. Wang & J. Fraser Stoddart & Samuel I. Stupp - 16-17 Overestimate of committed warming
by Gavin A. Schmidt & Jeff Severinghaus & Ayako Abe-Ouchi & Richard B. Alley & Wallace Broecker & Ed Brook & David Etheridge & Kenji Kawamura & Ralph F. Keeling & Margaret Leinen & Kate Marvel & Thomas F. Stocker - 17-18 Snyder replies
by Carolyn W. Snyder - 139-139 Kill the myth of the miracle machine
by Daniel Sarewitz - 145-146 White House’s dwindling science office leaves major research programmes in limbo
by Sara Reardon - 146-147 Why planetary scientists want better fake space dirt
by Alexandra Witze - 147-147 Massive database of 182,000 leaves is helping predict plants' family trees
by Heidi Ledford - 148-148 Tricks to mute quantum noise aid hunt for gravitational waves
by Elizabeth Gibney - 149-149 Ancient-genome studies grapple with Africa’s past
by Ewen Callaway - 150-152 How poverty affects the brain
by Carina Storrs - 153-155 Stop Alzheimer’s before it starts
by Eric McDade & Randall J. Bateman - 156-158 Witness gravity’s quantum side in the lab
by Chiara Marletto & Vlatko Vedral - 159-159 Information technology: A digital genius at play
by Vint Cerf - 160-161 History: Science lessons from the Gulag
by Asif Siddiqi - 161-161 Books in brief
by Barbara Kiser - 162-162 Switch it off on eclipse day
by Steve Elgar - 162-162 Manage chemicals and waste globally
by Quanyin Tan & Jinhui Li - 162-162 Taxonomy: refine rather than stabilize
by Fenton P. D. Cotterill & Colin P. Groves & Peter J. Taylor - 162-162 Philanthropic risks can hit home runs
by Melissa L. Stevens - 162-162 CRISPR book review — Doudna responds
by Jennifer Doudna - 164-165 Sensing past the quantum limit
by Christopher G. Baker & Warwick P. Bowen - 165-167 Precision T-cell therapy targets tumours
by Cornelis J. M. Melief - 167-168 Arctic plants take up mercury vapour
by William Shotyk - 168-169 A liquid reservoir for silent chromatin
by Adam Klosin & Anthony A. Hyman - 170-171 Taming tangled tau
by David S. Eisenberg & Michael R. Sawaya - 171-172 Bile ducts regenerated
by Ludi Zhang & Lijian Hui - 173-178 Fine-mapping inflammatory bowel disease loci to single-variant resolution
by Hailiang Huang & Ming Fang & Luke Jostins & Maša Umićević Mirkov & Gabrielle Boucher & Carl A. Anderson & Vibeke Andersen & Isabelle Cleynen & Adrian Cortes & François Crins & Mauro D’Amato & Valérie Deffontaine & Julia Dmitrieva & Elisa Docampo & Mahmoud Elansary & Kyle Kai-How Farh & Andre Franke & Ann-Stephan Gori & Philippe Goyette & Jonas Halfvarson & Talin Haritunians & Jo Knight & Ian C. Lawrance & Charlie W. Lees & Edouard Louis & Rob Mariman & Theo Meuwissen & Myriam Mni & Yukihide Momozawa & Miles Parkes & Sarah L. Spain & Emilie Théâtre & Gosia Trynka & Jack Satsangi & Suzanne van Sommeren & Severine Vermeire & Ramnik J. Xavier & Rinse K. Weersma & Richard H. Duerr & Christopher G. Mathew & John D. Rioux & Dermot P. B. McGovern & Judy H. Cho & Michel Georges & Mark J. Daly & Jeffrey C. Barrett - 179-184 The extracellular matrix protein agrin promotes heart regeneration in mice
by Elad Bassat & Yara Eid Mutlak & Alex Genzelinakh & Ilya Y. Shadrin & Kfir Baruch Umansky & Oren Yifa & David Kain & Dana Rajchman & John Leach & Daria Riabov Bassat & Yael Udi & Rachel Sarig & Irit Sagi & James F. Martin & Nenad Bursac & Shenhav Cohen & Eldad Tzahor - 185-190 Cryo-EM structures of tau filaments from Alzheimer’s disease
by Anthony W. P. Fitzpatrick & Benjamin Falcon & Shaoda He & Alexey G. Murzin & Garib Murshudov & Holly J. Garringer & R. Anthony Crowther & Bernardino Ghetti & Michel Goedert & Sjors H. W. Scheres - 191-195 Quantum back-action-evading measurement of motion in a negative mass reference frame
by Christoffer B. Møller & Rodrigo A. Thomas & Georgios Vasilakis & Emil Zeuthen & Yeghishe Tsaturyan & Mikhail Balabas & Kasper Jensen & Albert Schliesser & Klemens Hammerer & Eugene S. Polzik - 196-200 Catalytic allylic oxidation of internal alkenes to a multifunctional chiral building block
by Liela Bayeh & Phong Q. Le & Uttam K. Tambar - 201-204 Tundra uptake of atmospheric elemental mercury drives Arctic mercury pollution
by Daniel Obrist & Yannick Agnan & Martin Jiskra & Christine L. Olson & Dominique P. Colegrove & Jacques Hueber & Christopher W. Moore & Jeroen E. Sonke & Detlev Helmig - 205-208 The pyrite-type high-pressure form of FeOOH
by Masayuki Nishi & Yasuhiro Kuwayama & Jun Tsuchiya & Taku Tsuchiya - 209-212 Pre-oral gut contributes to facial structures in non-teleost fishes
by Martin Minarik & Jan Stundl & Peter Fabian & David Jandzik & Brian D. Metscher & Martin Psenicka & David Gela & Adriana Osorio-Pérez & Lenin Arias-Rodriguez & Ivan Horácek & Robert Cerny - 213-216 Nutrient sensing modulates malaria parasite virulence
by Liliana Mancio-Silva & Ksenija Slavic & Margarida T. Grilo Ruivo & Ana Rita Grosso & Katarzyna K. Modrzynska & Iset Medina Vera & Joana Sales-Dias & Ana Rita Gomes & Cameron Ross MacPherson & Pierre Crozet & Mattia Adamo & Elena Baena-Gonzalez & Rita Tewari & Manuel Llinás & Oliver Billker & Maria M. Mota - 217-221 An immunogenic personal neoantigen vaccine for patients with melanoma
by Patrick A. Ott & Zhuting Hu & Derin B. Keskin & Sachet A. Shukla & Jing Sun & David J. Bozym & Wandi Zhang & Adrienne Luoma & Anita Giobbie-Hurder & Lauren Peter & Christina Chen & Oriol Olive & Todd A. Carter & Shuqiang Li & David J. Lieb & Thomas Eisenhaure & Evisa Gjini & Jonathan Stevens & William J. Lane & Indu Javeri & Kaliappanadar Nellaiappan & Andres M. Salazar & Heather Daley & Michael Seaman & Elizabeth I. Buchbinder & Charles H. Yoon & Maegan Harden & Niall Lennon & Stacey Gabriel & Scott J. Rodig & Dan H. Barouch & Jon C. Aster & Gad Getz & Kai Wucherpfennig & Donna Neuberg & Jerome Ritz & Eric S. Lander & Edward F. Fritsch & Nir Hacohen & Catherine J. Wu - 222-226 Personalized RNA mutanome vaccines mobilize poly-specific therapeutic immunity against cancer
by Ugur Sahin & Evelyna Derhovanessian & Matthias Miller & Björn-Philipp Kloke & Petra Simon & Martin Löwer & Valesca Bukur & Arbel D. Tadmor & Ulrich Luxemburger & Barbara Schrörs & Tana Omokoko & Mathias Vormehr & Christian Albrecht & Anna Paruzynski & Andreas N. Kuhn & Janina Buck & Sandra Heesch & Katharina H. Schreeb & Felicitas Müller & Inga Ortseifer & Isabel Vogler & Eva Godehardt & Sebastian Attig & Richard Rae & Andrea Breitkreuz & Claudia Tolliver & Martin Suchan & Goran Martic & Alexander Hohberger & Patrick Sorn & Jan Diekmann & Janko Ciesla & Olga Waksmann & Alexandra-Kemmer Brück & Meike Witt & Martina Zillgen & Andree Rothermel & Barbara Kasemann & David Langer & Stefanie Bolte & Mustafa Diken & Sebastian Kreiter & Romina Nemecek & Christoffer Gebhardt & Stephan Grabbe & Christoph Höller & Jochen Utikal & Christoph Huber & Carmen Loquai & Özlem Türeci - 227-231 Dystrophin–glycoprotein complex sequesters Yap to inhibit cardiomyocyte proliferation
by Yuka Morikawa & Todd Heallen & John Leach & Yang Xiao & James F. Martin - 232-235 Allelic reprogramming of 3D chromatin architecture during early mammalian development
by Zhenhai Du & Hui Zheng & Bo Huang & Rui Ma & Jingyi Wu & Xianglin Zhang & Jing He & Yunlong Xiang & Qiujun Wang & Yuanyuan Li & Jing Ma & Xu Zhang & Ke Zhang & Yang Wang & Michael Q. Zhang & Juntao Gao & Jesse R. Dixon & Xiaowo Wang & Jianyang Zeng & Wei Xie - 236-240 Liquid droplet formation by HP1α suggests a role for phase separation in heterochromatin
by Adam G. Larson & Daniel Elnatan & Madeline M. Keenen & Michael J. Trnka & Jonathan B. Johnston & Alma L. Burlingame & David A. Agard & Sy Redding & Geeta J. Narlikar - 241-245 Phase separation drives heterochromatin domain formation
by Amy R. Strom & Alexander V. Emelyanov & Mustafa Mir & Dmitry V. Fyodorov & Xavier Darzacq & Gary H. Karpen - 246-246 Retraction Note: Oncogenic activity of Cdc6 through repression of the INK4/ARF locus
by Susana Gonzalez & Peter Klatt & Sonia Delgado & Esther Conde & Fernando Lopez-Rios & Montserrat Sanchez-Cespedes & Juan Mendez & Francisco Antequera & Manuel Serrano - 246-246 Correction: Corrigendum: Mineral supply for sustainable development requires resource governance
by Saleem H. Ali & Damien Giurco & Nicholas Arndt & Edmund Nickless & Graham Brown & Alecos Demetriades & Ray Durrheim & Maria Amélia Enriquez & Judith Kinnaird & Anna Littleboy & Lawrence D. Meinert & Roland Oberhänsli & Janet Salem & Richard Schodde & Gabi Schneider & Olivier Vidal & Natalia Yakovleva - 247-249 Housing: A home on a budget
by Chris Woolston - 249-249 Turning point: Tenacious chemist
by Virginia Gewin - 252-252 Legs-11
by Hugh Cartwright
July 2017, Volume 547, Issue 7661
- 1-3 Upholding a role for EMT in breast cancer metastasis
by Xin Ye & Thomas Brabletz & Yibin Kang & Gregory D. Longmore & M. Angela Nieto & Ben Z. Stanger & Jing Yang & Robert A. Weinberg - 5-6 Fischer et al. reply
by Kari R. Fischer & Nasser K. Altorki & Vivek Mittal & Dingcheng Gao - 7-7 Our obsession with eminence warps research
by Simine Vazire - 7-8 Upholding a role for EMT in pancreatic cancer metastasis
by Nicole M. Aiello & Thomas Brabletz & Yibin Kang & M. Angela Nieto & Robert A. Weinberg & Ben Z. Stanger - 13-14 Google spin-off deploys wearable electronics for huge health study
by Amy Maxmen - 14-15 Ebola outbreak in Africa ends — but gaps in public health leave region vulnerable
by Erika Check Hayden - 15-15 Has Harry Potter mania cursed Indonesia's owls?
by Inga Vesper - 16-16 Qatar blockade hits helium supply
by Declan Butler - 17-17 Europe’s next big science-funding programme urged to double its budget
by Alison Abbott - 20-22 The trickiest family tree in biology
by Ewen Callaway - 27-29 Immunology, one cell at a time
by Amir Giladi & Ido Amit - 30-31 Cybersecurity: The cold war online
by Steven Aftergood - 31-31 Books in brief
by Barbara Kiser - 32-32 Japan disregards whaling review again
by Phillip J. Clapham - 32-32 Stop ruining Turkey's geological heritage
by A. M. Celal Şengör & Nalan Lom - 32-32 Defend real science in the Balkans
by Jelena Kalinić - 32-32 AI zooms in on highly influential citations
by Oren Etzioni - 32-32 Flagging gender bias doesn't always work
by Greta Faccio - 34-35 Continuous chromatin changes
by Robert A. Beagrie & Ana Pombo - 35-36 Ice-sheet history revealed by fossils
by Jennifer Hertzberg - 36-38 The patterns of T-cell target recognition
by Sai T. Reddy - 38-39 3D integration advances computing
by Sherief Reda - 40-41 Less is more in the hunt for driver mutations
by Sushant Kumar & Mark Gerstein - 41-42 Stellar siblings grow closer with age
by Aaron M. Geller - 43-48 West Antarctic Ice Sheet retreat driven by Holocene warm water incursions
by Claus-Dieter Hillenbrand & James A. Smith & David A. Hodell & Mervyn Greaves & Christopher R. Poole & Sev Kender & Mark Williams & Thorbjørn Joest Andersen & Patrycja E. Jernas & Henry Elderfield & Johann P. Klages & Stephen J. Roberts & Karsten Gohl & Robert D. Larter & Gerhard Kuhn - 49-54 Climate change drives expansion of Antarctic ice-free habitat
by Jasmine R. Lee & Ben Raymond & Thomas J. Bracegirdle & Iadine Chadès & Richard A. Fuller & Justine D. Shaw & Aleks Terauds - 55-60 Recurrent and functional regulatory mutations in breast cancer
by Esther Rheinbay & Prasanna Parasuraman & Jonna Grimsby & Grace Tiao & Jesse M. Engreitz & Jaegil Kim & Michael S. Lawrence & Amaro Taylor-Weiner & Sergio Rodriguez-Cuevas & Mara Rosenberg & Julian Hess & Chip Stewart & Yosef E. Maruvka & Petar Stojanov & Maria L. Cortes & Sara Seepo & Carrie Cibulskis & Adam Tracy & Trevor J. Pugh & Jesse Lee & Zongli Zheng & Leif W. Ellisen & A. John Iafrate & Jesse S. Boehm & Stacey B. Gabriel & Matthew Meyerson & Todd R. Golub & Jose Baselga & Alfredo Hidalgo-Miranda & Toshi Shioda & Andre Bernards & Eric S. Lander & Gad Getz - 61-67 Cell-cycle dynamics of chromosomal organization at single-cell resolution
by Takashi Nagano & Yaniv Lubling & Csilla Várnai & Carmel Dudley & Wing Leung & Yael Baran & Netta Mendelson Cohen & Steven Wingett & Peter Fraser & Amos Tanay - 68-73 Single-molecule analysis of ligand efficacy in β2AR–G-protein activation
by G. Glenn Gregorio & Matthieu Masureel & Daniel Hilger & Daniel S. Terry & Manuel Juette & Hong Zhao & Zhou Zhou & Jose Manuel Perez-Aguilar & Maria Hauge & Signe Mathiasen & Jonathan A. Javitch & Harel Weinstein & Brian K. Kobilka & Scott C. Blanchard - 74-78 Three-dimensional integration of nanotechnologies for computing and data storage on a single chip
by Max M. Shulaker & Gage Hills & Rebecca S. Park & Roger T. Howe & Krishna Saraswat & H.-S. Philip Wong & Subhasish Mitra - 79-83 Selective sp3 C–H alkylation via polarity-match-based cross-coupling
by Chip Le & Yufan Liang & Ryan W. Evans & Ximing Li & David W. C. MacMillan - 84-88 Episodic kinematics in continental rifts modulated by changes in mantle melt fraction
by Simon Lamb & James D. P. Moore & Euan Smith & Tim Stern - 89-93 Quantifiable predictive features define epitope-specific T cell receptor repertoires
by Pradyot Dash & Andrew J. Fiore-Gartland & Tomer Hertz & George C. Wang & Shalini Sharma & Aisha Souquette & Jeremy Chase Crawford & E. Bridie Clemens & Thi H. O. Nguyen & Katherine Kedzierska & Nicole L. La Gruta & Philip Bradley & Paul G. Thomas - 94-98 Identifying specificity groups in the T cell receptor repertoire
by Jacob Glanville & Huang Huang & Allison Nau & Olivia Hatton & Lisa E. Wagar & Florian Rubelt & Xuhuai Ji & Arnold Han & Sheri M. Krams & Christina Pettus & Nikhil Haas & Cecilia S. Lindestam Arlehamn & Alessandro Sette & Scott D. Boyd & Thomas J. Scriba & Olivia M. Martinez & Mark M. Davis - 99-103 Chemotherapy drugs induce pyroptosis through caspase-3 cleavage of a gasdermin
by Yupeng Wang & Wenqing Gao & Xuyan Shi & Jingjin Ding & Wang Liu & Huabin He & Kun Wang & Feng Shao - 104-108 Tracing the origins of relapse in acute myeloid leukaemia to stem cells
by Liran I. Shlush & Amanda Mitchell & Lawrence Heisler & Sagi Abelson & Stanley W. K. Ng & Aaron Trotman-Grant & Jessie J. F. Medeiros & Abilasha Rao-Bhatia & Ivana Jaciw-Zurakowsky & Rene Marke & Jessica L. McLeod & Monica Doedens & Gary Bader & Veronique Voisin & ChangJiang Xu & John D. McPherson & Thomas J. Hudson & Jean C. Y. Wang & Mark D. Minden & John E. Dick - 109-113 mTORC1-dependent AMD1 regulation sustains polyamine metabolism in prostate cancer
by Amaia Zabala-Letona & Amaia Arruabarrena-Aristorena & Natalia Martín-Martín & Sonia Fernandez-Ruiz & James D. Sutherland & Michelle Clasquin & Julen Tomas-Cortazar & Jose Jimenez & Ines Torres & Phong Quang & Pilar Ximenez-Embun & Ruzica Bago & Aitziber Ugalde-Olano & Ana Loizaga-Iriarte & Isabel Lacasa-Viscasillas & Miguel Unda & Verónica Torrano & Diana Cabrera & Sebastiaan M. van Liempd & Ylenia Cendon & Elena Castro & Stuart Murray & Ajinkya Revandkar & Andrea Alimonti & Yinan Zhang & Amelia Barnett & Gina Lein & David Pirman & Ana R. Cortazar & Leire Arreal & Ludmila Prudkin & Ianire Astobiza & Lorea Valcarcel-Jimenez & Patricia Zuñiga-García & Itziar Fernandez-Dominguez & Marco Piva & Alfredo Caro-Maldonado & Pilar Sánchez-Mosquera & Mireia Castillo-Martín & Violeta Serra & Naiara Beraza & Antonio Gentilella & George Thomas & Mikel Azkargorta & Felix Elortza & Rosa Farràs & David Olmos & Alejo Efeyan & Juan Anguita & Javier Muñoz & Juan M. Falcón-Pérez & Rosa Barrio & Teresa Macarulla & Jose M. Mato & Maria L. Martinez-Chantar & Carlos Cordon-Cardo & Ana M. Aransay & Kevin Marks & José Baselga & Josep Tabernero & Paolo Nuciforo & Brendan D. Manning & Katya Marjon & Arkaitz Carracedo - 114-117 RNase III nucleases from diverse kingdoms serve as antiviral effectors
by Lauren C. Aguado & Sonja Schmid & Jared May & Leah R. Sabin & Maryline Panis & Daniel Blanco-Melo & Jaehee V. Shim & David Sachs & Sara Cherry & Anne E. Simon & Jean-Pierre Levraud & Benjamin R. tenOever - 118-122 Electron cryo-microscopy structure of the mechanotransduction channel NOMPC
by Peng Jin & David Bulkley & Yanmeng Guo & Wei Zhang & Zhenhao Guo & Walter Huynh & Shenping Wu & Shan Meltzer & Tong Cheng & Lily Yeh Jan & Yuh-Nung Jan & Yifan Cheng - 123-124 Addendum: Immune clearance of highly pathogenic SIV infection
by Scott G. Hansen & Michael Piatak & Abigail B. Ventura & Colette M. Hughes & Roxanne M. Gilbride & Julia C. Ford & Kelli Oswald & Rebecca Shoemaker & Yuan Li & Matthew S. Lewis & Awbrey N. Gilliam & Guangwu Xu & Nathan Whizin & Benjamin J. Burwitz & Shannon L. Planer & John M. Turner & Alfred W. Legasse & Michael K. Axthelm & Jay A. Nelson & Klaus Früh & Jonah B. Sacha & Jacob D. Estes & Brandon F. Keele & Paul T. Edlefsen & Jeffrey D. Lifson & Louis J. Picker - 125-126 Single-cell sequencing made simple
by Jeffrey M. Perkel - 127-129 Glycobiology: Sweet success
by Esther Landhuis - 129-129 Turning point: Single-cell mapper
by Virginia Gewin - 132-132 The ghost in the machine
by Anna Novitzky
June 2017, Volume 546, Issue 7660
- 6-7 Contesting the evidence for limited human lifespan
by Nicholas J. L. Brown & Casper J. Albers & Stuart J. Ritchie - 7-7 Dong et al. reply
by Xiao Dong & Brandon Milholland & Jan Vijg - 8-9 Many possible maximum lifespan trajectories
by Bryan G. Hughes & Siegfried Hekimi - 9-10 Dong et al. reply
by Xiao Dong & Brandon Milholland & Jan Vijg - 11-12 Is there evidence for a limit to human lifespan?
by Maarten P. Rozing & Thomas B. L. Kirkwood & Rudi G. J. Westendorp - 12-12 Dong et al. reply
by Xiao Dong & Brandon Milholland & Jan Vijg - 13-14 Questionable evidence for a limit to human lifespan
by Adam Lenart & James W. Vaupel - 14-15 Dong et al. reply
by Xiao Dong & Brandon Milholland & Jan Vijg - 16-17 Maximum human lifespan may increase to 125 years
by Joop de Beer & Anastasios Bardoutsos & Fanny Janssen - 21-21 Dong et al. reply
by Xiao Dong & Brandon Milholland & Jan Vijg - 577-577 Let science be a springboard for politics
by James Martin - 583-584 Success of gravity-wave satellite paves way for three-craft mission
by Davide Castelvecchi - 584-585 Scientists in limbo as US Supreme Court allows modified travel ban
by Sara Reardon - 585-586 Overlooked water loss in plants could throw off climate models
by Heidi Ledford - 586-587 Air guns used in offshore oil exploration can kill tiny marine life
by Jeff Tollefson - 587-588 Modified viruses deliver death to antibiotic-resistant bacteria
by Sara Reardon - 590-592 How quantum trickery can scramble cause and effect
by Philip Ball - 593-595 Three years to safeguard our climate
by Christiana Figueres & Hans Joachim Schellnhuber & Gail Whiteman & Johan Rockström & Anthony Hobley & Stefan Rahmstorf - 596-597 Astrobiology: Hunting aliens
by Ramin Skibba - 597-597 Books in brief
by Barbara Kiser - 598-598 Medicine: Heroes of global health
by Amy Maxmen - 599-599 Growing threat of urban waste dumps
by Huabo Duan & Jinhui Li & Gang Liu - 599-599 Taxonomy: naming algae, fungi, plants
by Vicki A. Funk & Patrick Herendeen & Sandra Knapp - 599-599 'Flammable ice' — extract with caution
by Haoran Dong & Guangming Zeng - 599-600 Taxonomy: use the red list as a registry
by Klaas-Douwe B. Dijkstra - 600-600 Taxonomy: swallow the costly medicine
by John Buckeridge - 600-600 Taxonomy: the IUBS responds
by Hiroyuki Takeda - 600-600 Taxonomy: retain scientific autonomy
by Markus Lambertz - 600-600 Bibliometrics: An obituary for the impact factor
by Richard J. Roberts - 600-600 Taxonomy: avoid extra bureaucracy
by Peter M. Hollingsworth - 602-603 A larger quantum alphabet
by Roberto Osellame - 603-604 Predictions of virus spillover across species
by James O. Lloyd-Smith - 604-606 A light-fuelled wave machine
by Yanlei Yu - 606-608 Gut sensor halts viral attack
by Pedro H. V. Saavedra & Mohamed Lamkanfi - 608-609 The fingerprints of reaction mechanisms
by Claire Vallance - 609-610 Lymphatic detours for cancer
by Ayuko Hoshino & David Lyden - 611-616 Homeostatic circuits selectively gate food cue responses in insular cortex
by Yoav Livneh & Rohan N. Ramesh & Christian R. Burgess & Kirsten M. Levandowski & Joseph C. Madara & Henning Fenselau & Glenn J. Goldey & Veronica E. Diaz & Nick Jikomes & Jon M. Resch & Bradford B. Lowell & Mark L. Andermann - 617-621 Structure of a pre-catalytic spliceosome
by Clemens Plaschka & Pei-Chun Lin & Kiyoshi Nagai - 622-626 On-chip generation of high-dimensional entangled quantum states and their coherent control
by Michael Kues & Christian Reimer & Piotr Roztocki & Luis Romero Cortés & Stefania Sciara & Benjamin Wetzel & Yanbing Zhang & Alfonso Cino & Sai T. Chu & Brent E. Little & David J. Moss & Lucia Caspani & José Azaña & Roberto Morandotti - 627-631 Observation of three-component fermions in the topological semimetal molybdenum phosphide
by B. Q. Lv & Z.-L. Feng & Q.-N. Xu & X. Gao & J.-Z. Ma & L.-Y. Kong & P. Richard & Y.-B. Huang & V. N. Strocov & C. Fang & H.-M. Weng & Y.-G. Shi & T. Qian & H. Ding - 632-636 Making waves in a photoactive polymer film
by Anne Helene Gelebart & Dirk Jan Mulder & Michael Varga & Andrew Konya & Ghislaine Vantomme & E. W. Meijer & Robin L. B. Selinger & Dirk J. Broer - 637-641 Surface tension prevails over solute effect in organic-influenced cloud droplet activation
by Jurgita Ovadnevaite & Andreas Zuend & Ari Laaksonen & Kevin J. Sanchez & Greg Roberts & Darius Ceburnis & Stefano Decesari & Matteo Rinaldi & Natasha Hodas & Maria Cristina Facchini & John H. Seinfeld & Colin O’ Dowd - 642-645 Hidden morphological diversity among early tetrapods
by Jason D. Pardo & Matt Szostakiwskyj & Per E. Ahlberg & Jason S. Anderson - 646-650 Host and viral traits predict zoonotic spillover from mammals
by Kevin J. Olival & Parviez R. Hosseini & Carlos Zambrana-Torrelio & Noam Ross & Tiffany L. Bogich & Peter Daszak - 651-655 Trans-kingdom mimicry underlies ribosome customization by a poxvirus kinase
by Sujata Jha & Madeline G. Rollins & Gabriele Fuchs & Dean J. Procter & Elizabeth A. Hall & Kira Cozzolino & Peter Sarnow & Jeffrey N. Savas & Derek Walsh - 656-661 T cells from patients with Parkinson’s disease recognize α-synuclein peptides
by David Sulzer & Roy N. Alcalay & Francesca Garretti & Lucien Cote & Ellen Kanter & Julian Agin-Liebes & Christopher Liong & Curtis McMurtrey & William H. Hildebrand & Xiaobo Mao & Valina L. Dawson & Ted M. Dawson & Carla Oseroff & John Pham & John Sidney & Myles B. Dillon & Chelsea Carpenter & Daniela Weiskopf & Elizabeth Phillips & Simon Mallal & Bjoern Peters & April Frazier & Cecilia S. Lindestam Arlehamn & Alessandro Sette - 662-666 Human fetal dendritic cells promote prenatal T-cell immune suppression through arginase-2
by Naomi McGovern & Amanda Shin & Gillian Low & Donovan Low & Kaibo Duan & Leong Jing Yao & Rasha Msallam & Ivy Low & Nurhidaya Binte Shadan & Hermi R Sumatoh & Erin Soon & Josephine Lum & Esther Mok & Sandra Hubert & Peter See & Edwin Huang Kunxiang & Yie Hou Lee & Baptiste Janela & Mahesh Choolani & Citra Nurfarah Zaini Mattar & Yiping Fan & Tony Kiat Hon Lim & Dedrick Kok Hong Chan & Ker-Kan Tan & John Kit Chung Tam & Christopher Schuster & Adelheid Elbe-Bürger & Xiao-nong Wang & Venetia Bigley & Matthew Collin & Muzlifah Haniffa & Andreas Schlitzer & Michael Poidinger & Salvatore Albani & Anis Larbi & Evan W Newell & Jerry Kok Yen Chan & Florent Ginhoux - 667-670 Nlrp9b inflammasome restricts rotavirus infection in intestinal epithelial cells
by Shu Zhu & Siyuan Ding & Penghua Wang & Zheng Wei & Wen Pan & Noah W. Palm & Yi Yang & Hua Yu & Hua-Bing Li & Geng Wang & Xuqiu Lei & Marcel R. de Zoete & Jun Zhao & Yunjiang Zheng & Haiwei Chen & Yujiao Zhao & Kellie A. Jurado & Ningguo Feng & Liang Shan & Yuval Kluger & Jun Lu & Clara Abraham & Erol Fikrig & Harry B. Greenberg & Richard A. Flavell - 671-675 ERF mutations reveal a balance of ETS factors controlling prostate oncogenesis
by Rohit Bose & Wouter R. Karthaus & Joshua Armenia & Wassim Abida & Phillip J. Iaquinta & Zeda Zhang & John Wongvipat & Elizabeth V. Wasmuth & Neel Shah & Patrick S. Sullivan & Michael G. Doran & Ping Wang & Anna Patruno & Yilin Zhao & Deyou Zheng & Nikolaus Schultz & Charles L. Sawyers - 676-680 Whole-body imaging of lymphovascular niches identifies pre-metastatic roles of midkine
by David Olmeda & Daniela Cerezo-Wallis & Erica Riveiro-Falkenbach & Paula C. Pennacchi & Marta Contreras-Alcalde & Nuria Ibarz & Metehan Cifdaloz & Xavier Catena & Tonantzin G. Calvo & Estela Cañón & Direna Alonso-Curbelo & Javier Suarez & Lisa Osterloh & Osvaldo Graña & Francisca Mulero & Diego Megías & Marta Cañamero & Jorge L. Martínez-Torrecuadrada & Chandrani Mondal & Julie Di Martino & David Lora & Inés Martinez-Corral & J. Javier Bravo-Cordero & Javier Muñoz & Susana Puig & Pablo Ortiz-Romero & José L. Rodriguez-Peralto & Sagrario Ortega & María S. Soengas - 681-685 Crystal structure of the potassium-importing KdpFABC membrane complex
by Ching-Shin Huang & Bjørn Panyella Pedersen & David L. Stokes - 686-686 Correction: Corrigendum: Common genetic variation drives molecular heterogeneity in human iPSCs
by Helena Kilpinen & Angela Goncalves & Andreas Leha & Vackar Afzal & Kaur Alasoo & Sofie Ashford & Sendu Bala & Dalila Bensaddek & Francesco Paolo Casale & Oliver J. Culley & Petr Danecek & Adam Faulconbridge & Peter W. Harrison & Annie Kathuria & Davis McCarthy & Shane A. McCarthy & Ruta Meleckyte & Yasin Memari & Nathalie Moens & Filipa Soares & Alice Mann & Ian Streeter & Chukwuma A. Agu & Alex Alderton & Rachel Nelson & Sarah Harper & Minal Patel & Alistair White & Sharad R. Patel & Laura Clarke & Reena Halai & Christopher M. Kirton & Anja Kolb-Kokocinski & Philip Beales & Ewan Birney & Davide Danovi & Angus I. Lamond & Willem H. Ouwehand & Ludovic Vallier & Fiona M. Watt & Richard Durbin & Oliver Stegle & Daniel J. Gaffney - 686-686 Correction: Corrigendum: CD32a is a marker of a CD4 T-cell HIV reservoir harbouring replication-competent proviruses
by Benjamin Descours & Gaël Petitjean & José-Luis López-Zaragoza & Timothée Bruel & Raoul Raffel & Christina Psomas & Jacques Reynes & Christine Lacabaratz & Yves Levy & Olivier Schwartz & Jean Daniel Lelievre & Monsef Benkirane - 686-686 Correction: Corrigendum: Dermatologist-level classification of skin cancer with deep neural networks
by Andre Esteva & Brett Kuprel & Roberto A. Novoa & Justin Ko & Susan M. Swetter & Helen M. Blau & Sebastian Thrun - 687-689 The architecture of structured DNA
by XiaoZhi Lim - 691-692 Networking: High fliers
by Amber Dance - 693-693 Turning point: Tumour tactician
by Virginia Gewin - 693-693 Gender bias: Citation lag in astronomy
by Virginia Gewin - 696-696 Jurassic Jaws Jones
by Hal Y. Zhang
June 2017, Volume 546, Issue 7659
- 1-3 Effects of a ketamine metabolite on synaptic NMDAR function
by Kanzo Suzuki & Elena Nosyreva & Kevin W. Hunt & Ege T. Kavalali & Lisa M. Monteggia