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A computer model to analyse the cost-effectiveness of hormone replacement therapy - a revised version

Listed author(s):
  • Zethraeus, Niklas


    (Dept. of Economics, Stockholm School of Economics)

  • Lindgren, Peter

    (Dept. of Economics, Stockholm School of Economics)

  • Johnell, Olof

    (Department of Orthopaedics)

  • Jönsson, Bengt


    (Dept. of Economics, Stockholm School of Economics)

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    This report presents a computer model for evaluating the cost-effectiveness (CE) of Hormone Replacement Therapy (HRT). The model is an extension of a previous model and includes also the risk of spine and wrist fracture. New Swedish data on risk of coronary heart disease and related mortality are included. The report describes the model's structure and data requirements; it also investigates the impact on the CE results by using the new model and by adding the wrist and spine fractures to the model. We further investigate whether the results are sensitive to the inclusion of Swedish risk and mortality data for CHD instead of using data based on the Framingham study. The results show that the incremental cost-effectiveness ratios (ICERs) are insensitive to the chosen model, to the assumption that the risk of wrist and spine fracture follows that of hip fracture, and to replacing the Framingham data with Swedish CHD risk and mortality data.

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    Paper provided by Stockholm School of Economics in its series SSE/EFI Working Paper Series in Economics and Finance with number 368.

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    Length: 57 pages
    Date of creation: 20 Mar 2000
    Handle: RePEc:hhs:hastef:0368
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    1. David Meltzer, 1997. "Accounting for Future Costs in Medical Cost-Effectiveness Analysis," NBER Working Papers 5946, National Bureau of Economic Research, Inc.
    2. Meltzer, David, 1997. "Accounting for future costs in medical cost-effectiveness analysis," Journal of Health Economics, Elsevier, vol. 16(1), pages 33-64, February.
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