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Partial Identification of Causal Effects for Endogenous Continuous Treatments

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  • Abhinandan Dalal
  • Eric J. Tchetgen Tchetgen

Abstract

No unmeasured confounding is a common assumption when reasoning about counterfactual outcomes, but such an assumption may not be plausible in observational studies. Sensitivity analysis is often employed to assess the robustness of causal conclusions to unmeasured confounding, but existing methods are predominantly designed for binary treatments. In this paper, we provide natural extensions of two extensively used sensitivity frameworks -- the Rosenbaum and Marginal sensitivity models -- to the setting of continuous exposures. Our generalization replaces scalar sensitivity parameters with sensitivity functions that vary with exposure level, enabling richer modeling and sharper identification bounds. We develop a unified pseudo-outcome regression formulation for bounding the counterfactual dose-response curve under both models, and propose corresponding nonparametric estimators which have second order bias. These estimators accommodate modern machine learning methods for obtaining nuisance parameter estimators, which are shown to achieve $L^2$- consistency, minimax rates of convergence under suitable conditions. Our resulting estimators of bounds for the counterfactual dose-response curve are shown to be consistent and asymptotic normal allowing for a user-specified bound on the degree of uncontrolled exposure endogeneity. We also offer a geometric interpretation that relates the Rosenbaum and Marginal sensitivity model and guides their practical usage in global versus targeted sensitivity analysis. The methods are validated through simulations and a real-data application on the effect of second-hand smoke exposure on blood lead levels in children.

Suggested Citation

  • Abhinandan Dalal & Eric J. Tchetgen Tchetgen, 2025. "Partial Identification of Causal Effects for Endogenous Continuous Treatments," Papers 2508.13946, arXiv.org.
  • Handle: RePEc:arx:papers:2508.13946
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    References listed on IDEAS

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    1. R. Rockafellar & Stan Uryasev & Michael Zabarankin, 2006. "Generalized deviations in risk analysis," Finance and Stochastics, Springer, vol. 10(1), pages 51-74, January.
    2. Oliver Hines & Oliver Dukes & Karla Diaz-Ordaz & Stijn Vansteelandt, 2022. "Demystifying Statistical Learning Based on Efficient Influence Functions," The American Statistician, Taylor & Francis Journals, vol. 76(3), pages 292-304, July.
    3. Victor Chernozhukov & Denis Chetverikov & Mert Demirer & Esther Duflo & Christian Hansen & Whitney Newey & James Robins, 2018. "Double/debiased machine learning for treatment and structural parameters," Econometrics Journal, Royal Economic Society, vol. 21(1), pages 1-68, February.
    4. Heckman, James J. & UrzĂșa, Sergio, 2010. "Comparing IV with structural models: What simple IV can and cannot identify," Journal of Econometrics, Elsevier, vol. 156(1), pages 27-37, May.
    5. Tan, Zhiqiang, 2006. "A Distributional Approach for Causal Inference Using Propensity Scores," Journal of the American Statistical Association, American Statistical Association, vol. 101, pages 1619-1637, December.
    6. Belloni, Alexandre & Chernozhukov, Victor & Chetverikov, Denis & Kato, Kengo, 2015. "Some new asymptotic theory for least squares series: Pointwise and uniform results," Journal of Econometrics, Elsevier, vol. 186(2), pages 345-366.
    7. Colin B. Fogarty & Kwonsang Lee & Rachel R. Kelz & Luke J. Keele, 2021. "Biased Encouragements and Heterogeneous Effects in an Instrumental Variable Study of Emergency General Surgical Outcomes," Journal of the American Statistical Association, Taylor & Francis Journals, vol. 116(536), pages 1625-1636, October.
    8. Hua Yun Chen, 2007. "A Semiparametric Odds Ratio Model for Measuring Association," Biometrics, The International Biometric Society, vol. 63(2), pages 413-421, June.
    9. Cai, Zongwu, 2001. "Weighted Nadaraya-Watson regression estimation," Statistics & Probability Letters, Elsevier, vol. 51(3), pages 307-318, February.
    10. Huang, Jianhua Z., 2003. "Asymptotics for polynomial spline regression under weak conditions," Statistics & Probability Letters, Elsevier, vol. 65(3), pages 207-216, November.
    11. Jacob Dorn & Kevin Guo, 2023. "Sharp Sensitivity Analysis for Inverse Propensity Weighting via Quantile Balancing," Journal of the American Statistical Association, Taylor & Francis Journals, vol. 118(544), pages 2645-2657, October.
    12. Abhinandan Dalal & Patrick Blobaum & Shiva Kasiviswanathan & Aaditya Ramdas, 2024. "Anytime-Valid Inference for Double/Debiased Machine Learning of Causal Parameters," Papers 2408.09598, arXiv.org, revised Sep 2024.
    13. Farooq, Muhammad & Steinwart, Ingo, 2017. "An SVM-like approach for expectile regression," Computational Statistics & Data Analysis, Elsevier, vol. 109(C), pages 159-181.
    14. Cattaneo, Matias D. & Farrell, Max H., 2013. "Optimal convergence rates, Bahadur representation, and asymptotic normality of partitioning estimators," Journal of Econometrics, Elsevier, vol. 174(2), pages 127-143.
    15. Eric J. Tchetgen Tchetgen & James M. Robins & Andrea Rotnitzky, 2010. "On doubly robust estimation in a semiparametric odds ratio model," Biometrika, Biometrika Trust, vol. 97(1), pages 171-180.
    16. Rosenbaum, Paul R., 2010. "Design Sensitivity and Efficiency in Observational Studies," Journal of the American Statistical Association, American Statistical Association, vol. 105(490), pages 692-702.
    17. Jacob Dorn & Kevin Guo, 2021. "Sharp Sensitivity Analysis for Inverse Propensity Weighting via Quantile Balancing," Papers 2102.04543, arXiv.org, revised Aug 2023.
    18. Leamer, Edward E, 1985. "Sensitivity Analyses Would Help," American Economic Review, American Economic Association, vol. 75(3), pages 308-313, June.
    19. Jeffrey Zhang & Dylan S Small & Siyu Heng, 2024. "Sensitivity analysis for matched observational studies with continuous exposures and binary outcomes," Biometrika, Biometrika Trust, vol. 111(4), pages 1349-1368.
    20. Whitney K. Newey & James L. Powell, 2003. "Instrumental Variable Estimation of Nonparametric Models," Econometrica, Econometric Society, vol. 71(5), pages 1565-1578, September.
    21. Imbens,Guido W. & Rubin,Donald B., 2015. "Causal Inference for Statistics, Social, and Biomedical Sciences," Cambridge Books, Cambridge University Press, number 9780521885881, January.
    22. Wang Miao & Zhi Geng & Eric J Tchetgen Tchetgen, 2018. "Identifying causal effects with proxy variables of an unmeasured confounder," Biometrika, Biometrika Trust, vol. 105(4), pages 987-993.
    23. Melody Huang & Samuel D Pimentel, 2025. "Variance-based sensitivity analysis for weighting estimators results in more informative bounds," Biometrika, Biometrika Trust, vol. 112(1), pages 235-240.
    24. Vira Semenova & Victor Chernozhukov, 2021. "Debiased machine learning of conditional average treatment effects and other causal functions," The Econometrics Journal, Royal Economic Society, vol. 24(2), pages 264-289.
    25. Edward H. Kennedy & Zongming Ma & Matthew D. McHugh & Dylan S. Small, 2017. "Non-parametric methods for doubly robust estimation of continuous treatment effects," Journal of the Royal Statistical Society Series B, Royal Statistical Society, vol. 79(4), pages 1229-1245, September.
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