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Inference with few treated units

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  • Luis Alvarez
  • Bruno Ferman
  • Kaspar Wuthrich

Abstract

In many causal inference applications, only one or a few units (or clusters of units) are treated. An important challenge in such settings is that standard inference methods that rely on asymptotic theory may be unreliable, even when the total number of units is large. This survey reviews and categorizes inference methods that are designed to accommodate few treated units, considering both cross-sectional and panel data methods. We discuss trade-offs and connections between different approaches. In doing so, we propose slight modifications to improve the finite-sample validity of some methods, and we also provide theoretical justifications for existing heuristic approaches that have been proposed in the literature.

Suggested Citation

  • Luis Alvarez & Bruno Ferman & Kaspar Wuthrich, 2025. "Inference with few treated units," Papers 2504.19841, arXiv.org.
  • Handle: RePEc:arx:papers:2504.19841
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    References listed on IDEAS

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    1. Azeem M. Shaikh & Panos Toulis, 2021. "Randomization Tests in Observational Studies With Staggered Adoption of Treatment," Journal of the American Statistical Association, Taylor & Francis Journals, vol. 116(536), pages 1835-1848, October.
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    3. Marinho Bertanha & Eunyi Chung, 2023. "Permutation Tests at Nonparametric Rates," Journal of the American Statistical Association, Taylor & Francis Journals, vol. 118(544), pages 2833-2846, October.
    4. Bruno Ferman, 2021. "On the Properties of the Synthetic Control Estimator with Many Periods and Many Controls," Journal of the American Statistical Association, Taylor & Francis Journals, vol. 116(536), pages 1764-1772, October.
    5. Kirill Borusyak & Peter Hull, 2023. "Nonrandom Exposure to Exogenous Shocks," Econometrica, Econometric Society, vol. 91(6), pages 2155-2185, November.
    6. Athey, Susan & Imbens, Guido W., 2022. "Design-based analysis in Difference-In-Differences settings with staggered adoption," Journal of Econometrics, Elsevier, vol. 226(1), pages 62-79.
    7. Cai Yong & Canay Ivan A. & Kim Deborah & Shaikh Azeem M., 2023. "On the Implementation of Approximate Randomization Tests in Linear Models with a Small Number of Clusters," Journal of Econometric Methods, De Gruyter, vol. 12(1), pages 85-103, January.
    8. Chen, Xiaohong, 2007. "Large Sample Sieve Estimation of Semi-Nonparametric Models," Handbook of Econometrics, in: J.J. Heckman & E.E. Leamer (ed.), Handbook of Econometrics, edition 1, volume 6, chapter 76, Elsevier.
    9. Burt S. Barnow & Matias D. Cattaneo & Rocío Titiunik & Gonzalo Vazquez‐Bare, 2017. "Comparing Inference Approaches for RD Designs: A Reexamination of the Effect of Head Start on Child Mortality," Journal of Policy Analysis and Management, John Wiley & Sons, Ltd., vol. 36(3), pages 643-681, June.
    10. Luis Alvarez & Bruno Ferman, 2023. "Extensions for Inference in Difference-in-Differences with Few Treated Clusters," Papers 2302.03131, arXiv.org.
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