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Number Of R&D Alliances And Innovation Output — Nonlinear Relationship Evidence From The Pharmaceutical Industry

Author

Listed:
  • SHICHUN XU

    (School of Management, University of Michigan-Flint, Flint, MI 48502, USA)

  • ERIN CAVUSGIL

    (School of Management, University of Michigan-Flint, Flint, MI 48502, USA)

  • SEYDA DELIGONUL

    (Department of Management, St. John Fisher College, Rochester, NY 14618, USA)

Abstract

What is the precise nature of the relationship between a firm’s research and development alliance portfolio size and its innovation output? The existing literature is inconclusive between a positive linear relationship and a nonlinear variant. To address the issue, this study explores the relationship between alliance portfolio size and innovation output in the context of the pharmaceutical industry. Contrary to previous investigations, our results suggest increasing returns at a diminishing rate at a low to moderate alliance portfolio level while exhibiting increasingly higher returns at a moderate to high level of portfolio size. An advantage of the present investigation is that we draw from a larger data set of alliance agreements compared to earlier investigations. Additionally, the results provide improved reliability compared to previous studies where violations of some underlying assumptions have been overlooked. The paper concludes with a discussion of findings and suggestions for future research.

Suggested Citation

  • Shichun Xu & Erin Cavusgil & Seyda Deligonul, 2016. "Number Of R&D Alliances And Innovation Output — Nonlinear Relationship Evidence From The Pharmaceutical Industry," International Journal of Innovation Management (ijim), World Scientific Publishing Co. Pte. Ltd., vol. 20(06), pages 1-22, August.
    • Handle: RePEc:wsi:ijimxx:v:20:y:2016:i:06:n:s1363919616500602
    DOI: 10.1142/S1363919616500602
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    1. Lai, Wen-Hsiang & Chang, Pao-Long, 2010. "Corporate motivation and performance in R&D alliances," Journal of Business Research, Elsevier, vol. 63(5), pages 490-496, May.
    2. Bruce Kogut & Udo Zander, 1992. "Knowledge of the Firm, Combinative Capabilities, and the Replication of Technology," Organization Science, INFORMS, vol. 3(3), pages 383-397, August.
    3. Weijan Shan & Gordon Walker & Bruce Kogut, 1994. "Interfirm cooperation and startup innovation in the biotechnology industry," Strategic Management Journal, Wiley Blackwell, vol. 15(5), pages 387-394, June.
    4. Murray, Janet Y. & Kotabe, Masaaki, 2005. "Performance implications of strategic fit between alliance attributes and alliance forms," Journal of Business Research, Elsevier, vol. 58(11), pages 1525-1533, November.
    5. Valentina Lazzarotti & Raffaella Manzini, 2009. "Different Modes Of Open Innovation: A Theoretical Framework And An Empirical Study," International Journal of Innovation Management (ijim), World Scientific Publishing Co. Pte. Ltd., vol. 13(04), pages 615-636.
    6. Werner H. Hoffmann, 2007. "Strategies for managing a portfolio of alliances," Strategic Management Journal, Wiley Blackwell, vol. 28(8), pages 827-856, August.
    7. Alfredo J. Mauri & G. Steven Mcmillan, 1999. "The Influence Of Technology On Strategic Alliances: An Application Of The Utterback And Abernathy Model Of Product And Process Innovation," International Journal of Innovation Management (ijim), World Scientific Publishing Co. Pte. Ltd., vol. 3(04), pages 367-378.
    8. Gunno Park & Jina Kang, 2009. "The Effects of Teacher Firms: Characteristics and Student Firms: Absorptive Capacity on Firm Performance in Technology Alliances," TEMEP Discussion Papers 200909, Seoul National University; Technology Management, Economics, and Policy Program (TEMEP), revised Aug 2009.
    9. Calantone, Roger J. & di Benedetto, C. Anthony & Bhoovaraghavan, Sriraman, 1994. "Examining the relationship between degree of innovation and new product success," Journal of Business Research, Elsevier, vol. 30(2), pages 143-148, June.
    10. Nielsen, Bo Bernhard, 2005. "The role of knowledge embeddedness in the creation of synergies in strategic alliances," Journal of Business Research, Elsevier, vol. 58(9), pages 1194-1204, September.
    11. Prashant Kale & Harbir Singh, 2007. "Building firm capabilities through learning: the role of the alliance learning process in alliance capability and firm‐level alliance success," Strategic Management Journal, Wiley Blackwell, vol. 28(10), pages 981-1000, October.
    12. Clercq, Dirk De & Menguc, Bulent & Auh, Seigyoung, 2009. "Unpacking the relationship between an innovation strategy and firm performance: The role of task conflict and political activity," Journal of Business Research, Elsevier, vol. 62(11), pages 1046-1053, November.
    13. Gunno Park & Jina Kang, 2009. "The Effects Of Teacher Firms' Characteristics And Student Firms' Absorptive Capacity On Firm Performance In Technology Alliances," International Journal of Innovation Management (ijim), World Scientific Publishing Co. Pte. Ltd., vol. 13(03), pages 393-409.
    14. Susan E. Feinberg & Anil K. Gupta, 2004. "Knowledge spillovers and the assignment of R&D responsibilities to foreign subsidiaries," Strategic Management Journal, Wiley Blackwell, vol. 25(8‐9), pages 823-845, August.
    15. Rachelle C. Sampson, 2005. "Experience effects and collaborative returns in R&D alliances," Strategic Management Journal, Wiley Blackwell, vol. 26(11), pages 1009-1031, November.
    16. Deeds, David L. & Hill, Charles W. L., 1996. "Strategic alliances and the rate of new product development: An empirical study of entrepreneurial biotechnology firms," Journal of Business Venturing, Elsevier, vol. 11(1), pages 41-55, January.
    17. Tim Minshall, 1999. "A Resource-Based View Of Alliances: The Case Of The Handheld Computer Industry," International Journal of Innovation Management (ijim), World Scientific Publishing Co. Pte. Ltd., vol. 3(02), pages 159-183.
    18. Joanne E. Oxley & Rachelle C. Sampson, 2004. "The scope and governance of international R&D alliances," Strategic Management Journal, Wiley Blackwell, vol. 25(8‐9), pages 723-749, August.
    19. Rebecca Henderson & Iain Cockburn, 1994. "Measuring Competence? Exploring Firm Effects in Pharmaceutical Research," Strategic Management Journal, Wiley Blackwell, vol. 15(S1), pages 63-84, December.
    20. Norman, Patricia M., 2004. "Knowledge acquisition, knowledge loss, and satisfaction in high technology alliances," Journal of Business Research, Elsevier, vol. 57(6), pages 610-619, June.
    21. Forrester, Rosalind H., 2000. "Capturing Learning and Applying Knowledge: An Investigation of the Use of Innovation Teams in Japanese and American Automotive Firms," Journal of Business Research, Elsevier, vol. 47(1), pages 35-45, January.
    22. Bruno Cassiman & Reinhilde Veugelers, 2006. "In Search of Complementarity in Innovation Strategy: Internal R& D and External Knowledge Acquisition," Management Science, INFORMS, vol. 52(1), pages 68-82, January.
    23. Walter, Jorge & Lechner, Christoph & Kellermanns, Franz W., 2007. "Knowledge transfer between and within alliance partners: Private versus collective benefits of social capital," Journal of Business Research, Elsevier, vol. 60(7), pages 698-710, July.
    24. Simpson, Penny M. & Siguaw, Judy A. & Enz, Cathy A., 2006. "Innovation orientation outcomes: The good and the bad," Journal of Business Research, Elsevier, vol. 59(10-11), pages 1133-1141, October.
    25. Ron Boschma, 2005. "Proximity and Innovation: A Critical Assessment," Regional Studies, Taylor & Francis Journals, vol. 39(1), pages 61-74.
    26. Frank T. Rothaermel & David L. Deeds, 2004. "Exploration and exploitation alliances in biotechnology: a system of new product development," Strategic Management Journal, Wiley Blackwell, vol. 25(3), pages 201-221, March.
    27. Tania Bucic & Liem Viet Ngo, 2013. "Achieving Alliance Innovation Via Alliance Learning: An Empirical Study," International Journal of Innovation Management (ijim), World Scientific Publishing Co. Pte. Ltd., vol. 17(04), pages 1-17.
    28. Peter Smith & Lisa Callagher & Xinlei Huang, 2014. "Alliance Scope And Firm Performance In The Biotechnology Industry," International Journal of Innovation Management (ijim), World Scientific Publishing Co. Pte. Ltd., vol. 18(03), pages 1-16.
    29. Emden, Zeynep & Yaprak, Attila & Cavusgil, S. Tamer, 2005. "Learning from experience in international alliances: antecedents and firm performance implications," Journal of Business Research, Elsevier, vol. 58(7), pages 883-892, July.
    30. DiMasi, Joseph A. & Hansen, Ronald W. & Grabowski, Henry G., 2003. "The price of innovation: new estimates of drug development costs," Journal of Health Economics, Elsevier, vol. 22(2), pages 151-185, March.
    31. Lee Fleming, 2001. "Recombinant Uncertainty in Technological Search," Management Science, INFORMS, vol. 47(1), pages 117-132, January.
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