IDEAS home Printed from https://ideas.repec.org/a/plo/pone00/0295325.html
   My bibliography  Save this article

Protocol for the development of a core outcome set for neonatal sepsis (NESCOS)

Author

Listed:
  • Petek Eylul Taneri
  • Jamie J Kirkham
  • Eleanor J Molloy
  • Linda Biesty
  • Richard A Polin
  • James L Wynn
  • Barbara J Stoll
  • Niranjan Kissoon
  • Kondwani Kawaza
  • Mandy Daly
  • Aoife Branagan
  • Lívia Nagy Bonnard
  • Eric Giannoni
  • Tobias Strunk
  • Magdalena Ohaja
  • Kenneth Mugabe
  • Denise Suguitani
  • Fiona Quirke
  • Declan Devane

Abstract

Neonatal sepsis is a serious public health problem; however, there is substantial heterogeneity in the outcomes measured and reported in research evaluating the effectiveness of the treatments. Therefore, we aim to develop a Core Outcome Set (COS) for studies evaluating the effectiveness of treatments for neonatal sepsis. Since a systematic review of key outcomes from randomised trials of therapeutic interventions in neonatal sepsis was published recently, we will complement this with a qualitative systematic review of the key outcomes of neonatal sepsis identified by parents, other family members, parent representatives, healthcare providers, policymakers, and researchers. We will interpret the outcomes of both studies using a previously established framework. Stakeholders across three different groups i.e., (1) researchers, (2) healthcare providers, and (3) patients’ parents/family members and parent representatives will rate the importance of the outcomes in an online Real-Time Delphi Survey. Afterwards, consensus meetings will be held to agree on the final COS through online discussions with key stakeholders. This COS is expected to minimize outcome heterogeneity in measurements and publications, improve comparability and synthesis, and decrease research waste.

Suggested Citation

  • Petek Eylul Taneri & Jamie J Kirkham & Eleanor J Molloy & Linda Biesty & Richard A Polin & James L Wynn & Barbara J Stoll & Niranjan Kissoon & Kondwani Kawaza & Mandy Daly & Aoife Branagan & Lívia Nag, 2023. "Protocol for the development of a core outcome set for neonatal sepsis (NESCOS)," PLOS ONE, Public Library of Science, vol. 18(12), pages 1-11, December.
    • Handle: RePEc:plo:pone00:0295325
    DOI: 10.1371/journal.pone.0295325
    as

    Download full text from publisher

    File URL: https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0295325
    Download Restriction: no
    File URL: https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0295325&type=printable
    Download Restriction: no
    File URL: https://libkey.io/10.1371/journal.pone.0295325?utm_source=ideas
    LibKey link: if access is restricted and if your library uses this service, LibKey will redirect you to where you can use your library subscription to access this item
    ---><---

    References listed on IDEAS

    as
    1. Manuel Serra & Nuno Antonio & Claudia Henriques & Carlos M. Afonso, 2021. "Promoting Sustainability through Regional Food and Wine Pairing," Sustainability, MDPI, vol. 13(24), pages 1-22, December.
    Full references (including those not matched with items on IDEAS)

    Most related items

    These are the items that most often cite the same works as this one and are cited by the same works as this one.
    1. Caterina Fucile Franceschini & Elisa Giampietri & Eugenio Pomarici, 2025. "What Defines the Perfect Wine Tourism Experience? Evidence from a Best–Worst Approach," Agriculture, MDPI, vol. 15(8), pages 1-21, April.
    2. Chris Roberts & Joel Reynolds & Mary Jo Dolasinski, 2022. "Meta-Analysis of Tourism Sustainability Research: 2019–2021," Sustainability, MDPI, vol. 14(6), pages 1-18, March.
    3. Bernardo Valente & Eduardo Medeiros, 2022. "The Impacts of EU Cohesion Policy on Sustainable Tourism: The Case of POSEUR in Algarve," Sustainability, MDPI, vol. 14(19), pages 1-15, October.
    4. Viorica Guțan & Larisa Șavga & Constanta Laura Zugravu & Diana Bucur & Gheorghe Adrian Zugravu, 2023. "Research on Consumer Perception Regarding Wine Products and Wine Tourism in the Republic of Moldova," Agriculture, MDPI, vol. 13(3), pages 1-16, March.
    5. Claire Lamoureux & Nindu Barbier & Tatiana Bouzdine-Chameeva, 2022. "Managing Wine Tourism and Biodiversity: The Art of Ambidexterity for Sustainability," Sustainability, MDPI, vol. 14(22), pages 1-18, November.

    More about this item

    Statistics

    Access and download statistics

    Corrections

    All material on this site has been provided by the respective publishers and authors. You can help correct errors and omissions. When requesting a correction, please mention this item's handle: RePEc:plo:pone00:0295325. See general information about how to correct material in RePEc.

    If you have authored this item and are not yet registered with RePEc, we encourage you to do it here. This allows to link your profile to this item. It also allows you to accept potential citations to this item that we are uncertain about.

    If CitEc recognized a bibliographic reference but did not link an item in RePEc to it, you can help with this form .

    If you know of missing items citing this one, you can help us creating those links by adding the relevant references in the same way as above, for each refering item. If you are a registered author of this item, you may also want to check the "citations" tab in your RePEc Author Service profile, as there may be some citations waiting for confirmation.

    For technical questions regarding this item, or to correct its authors, title, abstract, bibliographic or download information, contact: plosone (email available below). General contact details of provider: https://journals.plos.org/plosone/ .

    Please note that corrections may take a couple of weeks to filter through the various RePEc services.

    IDEAS is a RePEc service. RePEc uses bibliographic data supplied by the respective publishers.