IDEAS home Printed from https://ideas.repec.org/a/plo/pone00/0285165.html
   My bibliography  Save this article

Automatic classification of patients with myocardial infarction or myocarditis based only on clinical data: A quick response

Author

Listed:
  • Sheikh Shah Mohammad Motiur Rahman
  • Zhihao Chen
  • Alain Lalande
  • Thomas Decourselle
  • Alexandre Cochet
  • Thibaut Pommier
  • Yves Cottin
  • Michel Salomon
  • Raphaël Couturier

Abstract

Background: In acute cardiovascular disease management, the delay between the admission in a hospital emergency department and the assessment of the disease from a Delayed Enhancement cardiac MRI (DE-MRI) scan is one of the barriers for an immediate management of patients with suspected myocardial infarction or myocarditis. Objectives: This work targets patients who arrive at the hospital with chest pain and are suspected of having a myocardial infarction or a myocarditis. The main objective is to classify these patients based solely on clinical data in order to provide an early accurate diagnosis. Methods: Machine learning (ML) and ensemble approaches have been used to construct a framework to automatically classify the patients according to their clinical conditions. 10-fold cross-validation is used during the model’s training to avoid overfitting. Approaches such as Stratified, Over-sampling, Under-sampling, NearMiss, and SMOTE were tested in order to address the imbalance of the data (i.e. proportion of cases per pathology). The ground truth is provided by a DE-MRI exam (normal exam, myocarditis or myocardial infarction). Results: The stacked generalization technique with Over-sampling seems to be the best one providing more than 97% of accuracy corresponding to 11 wrong classifications among 537 cases. Generally speaking, ensemble classifiers such as Stacking provided the best prediction. The five most important features are troponin, age, tobacco, sex and FEVG calculated from echocardiography. Conclusion: Our study provides a reliable approach to classify the patients in emergency department between myocarditis, myocardial infarction or other patient condition from only clinical information, considering DE-MRI as ground-truth. Among the different machine learning and ensemble techniques tested, the stacked generalization technique is the best one providing an accuracy of 97.4%. This automatic classification could provide a quick answer before imaging exam such as cardiovascular MRI depending on the patient’s condition.

Suggested Citation

  • Sheikh Shah Mohammad Motiur Rahman & Zhihao Chen & Alain Lalande & Thomas Decourselle & Alexandre Cochet & Thibaut Pommier & Yves Cottin & Michel Salomon & Raphaël Couturier, 2023. "Automatic classification of patients with myocardial infarction or myocarditis based only on clinical data: A quick response," PLOS ONE, Public Library of Science, vol. 18(5), pages 1-18, May.
    • Handle: RePEc:plo:pone00:0285165
    DOI: 10.1371/journal.pone.0285165
    as

    Download full text from publisher

    File URL: https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0285165
    Download Restriction: no
    File URL: https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0285165&type=printable
    Download Restriction: no
    File URL: https://libkey.io/10.1371/journal.pone.0285165?utm_source=ideas
    LibKey link: if access is restricted and if your library uses this service, LibKey will redirect you to where you can use your library subscription to access this item
    ---><---

    References listed on IDEAS

    as
    1. Alain Lalande & Zhihao Chen & Thomas Decourselle & Abdul Qayyum & Thibaut Pommier & Luc Lorgis & Ezequiel de la Rosa & Alexandre Cochet & Yves Cottin & Dominique Ginhac & Michel Salomon & Raphaël Cout, 2020. "Emidec: A Database Usable for the Automatic Evaluation of Myocardial Infarction from Delayed-Enhancement Cardiac MRI," Data, MDPI, vol. 5(4), pages 1-8, September.
    2. Friedman, Jerome H., 2002. "Stochastic gradient boosting," Computational Statistics & Data Analysis, Elsevier, vol. 38(4), pages 367-378, February.
    Full references (including those not matched with items on IDEAS)

    Most related items

    These are the items that most often cite the same works as this one and are cited by the same works as this one.
    1. Mansoor, Umer & Jamal, Arshad & Su, Junbiao & Sze, N.N. & Chen, Anthony, 2023. "Investigating the risk factors of motorcycle crash injury severity in Pakistan: Insights and policy recommendations," Transport Policy, Elsevier, vol. 139(C), pages 21-38.
    2. Bissan Ghaddar & Ignacio Gómez-Casares & Julio González-Díaz & Brais González-Rodríguez & Beatriz Pateiro-López & Sofía Rodríguez-Ballesteros, 2023. "Learning for Spatial Branching: An Algorithm Selection Approach," INFORMS Journal on Computing, INFORMS, vol. 35(5), pages 1024-1043, September.
    3. Akash Malhotra, 2018. "A hybrid econometric-machine learning approach for relative importance analysis: Prioritizing food policy," Papers 1806.04517, arXiv.org, revised Aug 2020.
    4. Nahushananda Chakravarthy H G & Karthik M Seenappa & Sujay Raghavendra Naganna & Dayananda Pruthviraja, 2023. "Machine Learning Models for the Prediction of the Compressive Strength of Self-Compacting Concrete Incorporating Incinerated Bio-Medical Waste Ash," Sustainability, MDPI, vol. 15(18), pages 1-22, September.
    5. Tim Voigt & Martin Kohlhase & Oliver Nelles, 2021. "Incremental DoE and Modeling Methodology with Gaussian Process Regression: An Industrially Applicable Approach to Incorporate Expert Knowledge," Mathematics, MDPI, vol. 9(19), pages 1-26, October.
    6. Wen, Shaoting & Buyukada, Musa & Evrendilek, Fatih & Liu, Jingyong, 2020. "Uncertainty and sensitivity analyses of co-combustion/pyrolysis of textile dyeing sludge and incense sticks: Regression and machine-learning models," Renewable Energy, Elsevier, vol. 151(C), pages 463-474.
    7. Zhu, Haibin & Bai, Lu & He, Lidan & Liu, Zhi, 2023. "Forecasting realized volatility with machine learning: Panel data perspective," Journal of Empirical Finance, Elsevier, vol. 73(C), pages 251-271.
    8. Spiliotis, Evangelos & Makridakis, Spyros & Kaltsounis, Anastasios & Assimakopoulos, Vassilios, 2021. "Product sales probabilistic forecasting: An empirical evaluation using the M5 competition data," International Journal of Production Economics, Elsevier, vol. 240(C).
    9. Zhang, Ning & Li, Zhiying & Zou, Xun & Quiring, Steven M., 2019. "Comparison of three short-term load forecast models in Southern California," Energy, Elsevier, vol. 189(C).
    10. Smyl, Slawek & Hua, N. Grace, 2019. "Machine learning methods for GEFCom2017 probabilistic load forecasting," International Journal of Forecasting, Elsevier, vol. 35(4), pages 1424-1431.
    11. Barzin,Samira & Avner,Paolo & Maruyama Rentschler,Jun Erik & O’Clery,Neave, 2022. "Where Are All the Jobs ? A Machine Learning Approach for High Resolution Urban Employment Prediction inDeveloping Countries," Policy Research Working Paper Series 9979, The World Bank.
    12. Eike Emrich & Christian Pierdzioch, 2016. "Volunteering, Match Quality, and Internet Use," Schmollers Jahrbuch : Journal of Applied Social Science Studies / Zeitschrift für Wirtschafts- und Sozialwissenschaften, Duncker & Humblot, Berlin, vol. 136(2), pages 199-226.
    13. Kusiak, Andrew & Zheng, Haiyang & Song, Zhe, 2009. "On-line monitoring of power curves," Renewable Energy, Elsevier, vol. 34(6), pages 1487-1493.
    14. Zhu, Siying & Zhu, Feng, 2019. "Cycling comfort evaluation with instrumented probe bicycle," Transportation Research Part A: Policy and Practice, Elsevier, vol. 129(C), pages 217-231.
    15. Catherine Ikae & Jacques Savoy, 2022. "Gender identification on Twitter," Journal of the Association for Information Science & Technology, Association for Information Science & Technology, vol. 73(1), pages 58-69, January.
    16. Cao, Jason & Tao, Tao, 2025. "Can an identified environmental correlate of car ownership serve as a practical planning tool?," Transportation Research Part A: Policy and Practice, Elsevier, vol. 191(C).
    17. Barkan, Oren & Benchimol, Jonathan & Caspi, Itamar & Cohen, Eliya & Hammer, Allon & Koenigstein, Noam, 2023. "Forecasting CPI inflation components with Hierarchical Recurrent Neural Networks," International Journal of Forecasting, Elsevier, vol. 39(3), pages 1145-1162.
    18. Martijn Kagie & Michiel Van Wezel, 2007. "Hedonic price models and indices based on boosting applied to the Dutch housing market," Intelligent Systems in Accounting, Finance and Management, John Wiley & Sons, Ltd., vol. 15(3‐4), pages 85-106, July.
    19. Matthias Bogaert & Michel Ballings & Dirk Van den Poel, 2018. "Evaluating the importance of different communication types in romantic tie prediction on social media," Annals of Operations Research, Springer, vol. 263(1), pages 501-527, April.
    20. Dursun Delen & Hamed M. Zolbanin & Durand Crosby & David Wright, 2021. "To imprison or not to imprison: an analytics model for drug courts," Annals of Operations Research, Springer, vol. 303(1), pages 101-124, August.

    More about this item

    Statistics

    Access and download statistics

    Corrections

    All material on this site has been provided by the respective publishers and authors. You can help correct errors and omissions. When requesting a correction, please mention this item's handle: RePEc:plo:pone00:0285165. See general information about how to correct material in RePEc.

    If you have authored this item and are not yet registered with RePEc, we encourage you to do it here. This allows to link your profile to this item. It also allows you to accept potential citations to this item that we are uncertain about.

    If CitEc recognized a bibliographic reference but did not link an item in RePEc to it, you can help with this form .

    If you know of missing items citing this one, you can help us creating those links by adding the relevant references in the same way as above, for each refering item. If you are a registered author of this item, you may also want to check the "citations" tab in your RePEc Author Service profile, as there may be some citations waiting for confirmation.

    For technical questions regarding this item, or to correct its authors, title, abstract, bibliographic or download information, contact: plosone (email available below). General contact details of provider: https://journals.plos.org/plosone/ .

    Please note that corrections may take a couple of weeks to filter through the various RePEc services.

    IDEAS is a RePEc service. RePEc uses bibliographic data supplied by the respective publishers.