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Individual voices, collective health: a person-centered cross-sectional study to identify psychological drivers of vaccination attitudes

Author

Listed:
  • Giansanto Mosconi

    (University of Pavia)

  • Serena Barello

    (University of Pavia
    IRCCS Mondino Foundation)

  • Paola Bertuccio

    (University of Pavia)

  • Marcello Fiorentino

    (University of Pavia)

  • Tomaso Vecchi

    (University of Pavia
    IRCCS Mondino Foundation)

  • Anna Odone

    (University of Pavia
    Fondazione IRCCS Policlinico San Matteo)

Abstract

Although existing research identifies different profiles of vaccine-hesitant individuals, most studies focus on isolated psychological constructs, neglecting their interplay in shaping vaccination attitudes. Using data from an online survey of a representative sample of Italian adults, we examined vaccination attitudes through a person-centered methodology. We selected personal values, attitudes, and beliefs for their potential relevance to vaccination attitudes and conducted an exploratory factor analysis to reveal the latent relationships among these variables. This approach allowed us to identify four underlying psychological drivers: Eco-humanism (altruistic/biospheric values and connectedness to nature), Skeptical Perspective (distrust in science, conspiracy mentality, and spirituality), Goal-Driven Positive Mindset (hope and optimism), and Self-Centered Attitude (hedonic/egoistic values). We then assessed how adherence to each driver related to vaccination attitudes, as measured by the VAX-I scale, using multiple linear and quantile regression models. Results showed that higher adherence to Eco-humanism resulted in more positive vaccination attitudes, particularly lower mistrust in vaccine benefits and reduced concerns about pharmaceutical companies’ profiteering. In contrast, a stronger alignment with the Skeptical Perspective was linked to more negative attitudes, including increased mistrust in vaccine benefits, heightened concerns about vaccine safety and pharmaceutical companies’ profiteering, and a greater preference for natural immunity. Likewise, higher adherence to Self-Centered Attitude was tied to an overall more negative stance, particularly marked by amplified worries about unforeseen long-term effects, heightened concerns about pharmaceutical companies’ profiteering, and an increased preference for natural immunity. Goal-Driven Positive Mindset, although not significantly associated with overall vaccination attitudes, was inversely related to mistrust in vaccine benefits. These findings suggest that vaccination attitudes are shaped by distinct psychological profiles, supporting the development of tailored, human-centered vaccine promotion strategies.

Suggested Citation

  • Giansanto Mosconi & Serena Barello & Paola Bertuccio & Marcello Fiorentino & Tomaso Vecchi & Anna Odone, 2025. "Individual voices, collective health: a person-centered cross-sectional study to identify psychological drivers of vaccination attitudes," Palgrave Communications, Palgrave Macmillan, vol. 12(1), pages 1-12, December.
    • Handle: RePEc:pal:palcom:v:12:y:2025:i:1:d:10.1057_s41599-025-04834-8
    DOI: 10.1057/s41599-025-04834-8
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    1. Alexander Neaman & Pamela Pensini & Sarah Zabel & Siegmar Otto & Dmitry S. Ermakov & Elvira A. Dovletyarova & Elliot Burnham & Mónica Castro & Claudia Navarro-Villarroel, 2022. "The Prosocial Driver of Ecological Behavior: The Need for an Integrated Approach to Prosocial and Environmental Education," Sustainability, MDPI, vol. 14(7), pages 1-19, April.
    2. Suzanne C. Makarem & Michael F. Smith & Susan M. Mudambi & James M. Hunt, 2014. "Why People Do Not Always Follow the Doctor's Orders: The Role of Hope and Perceived Control," Journal of Consumer Affairs, Wiley Blackwell, vol. 48(3), pages 457-485, October.
    3. Marc Debus & Jale Tosun, 2021. "Political ideology and vaccination willingness: implications for policy design," Policy Sciences, Springer;Society of Policy Sciences, vol. 54(3), pages 477-491, September.
    4. Ford, R.M. & Anderson, N.M. & Nitschke, C. & Bennett, L.T. & Williams, K.J.H., 2017. "Psychological values and cues as a basis for developing socially relevant criteria and indicators for forest management," Forest Policy and Economics, Elsevier, vol. 78(C), pages 141-150.
    5. John Zelenski & Sara Warber & Jake M. Robinson & Alan C. Logan & Susan L. Prescott, 2023. "Nature Connection: Providing a Pathway from Personal to Planetary Health," Challenges, MDPI, vol. 14(1), pages 1-23, March.
    6. Patrick Sturgis & Ian Brunton-Smith & Jonathan Jackson, 2021. "Trust in science, social consensus and vaccine confidence," Nature Human Behaviour, Nature, vol. 5(11), pages 1528-1534, November.
    7. Vincenzo Carrieri & Leonardo Madio & Francesco Principe, 2019. "Vaccine hesitancy and (fake) news: Quasi‐experimental evidence from Italy," Health Economics, John Wiley & Sons, Ltd., vol. 28(11), pages 1377-1382, November.
    8. Prislin, R. & Dyer, J.A. & Blakely, C.H. & Johnson, C.D., 1998. "Immunization status and sociodemographic characteristics: The mediating role of beliefs, attitudes, and perceived control," American Journal of Public Health, American Public Health Association, vol. 88(12), pages 1821-1826.
    9. Thijs Bouman & Linda Steg & Thomas Dietz, 2021. "Insights from early COVID-19 responses about promoting sustainable action," Nature Sustainability, Nature, vol. 4(3), pages 194-200, March.
    10. Vanessa Woods & Melinda Knuth, 2023. "The Biophilia Reactivity Hypothesis: biophilia as a temperament trait, or more precisely, a domain specific attraction to biodiversity," Journal of Bioeconomics, Springer, vol. 25(3), pages 271-293, December.
    11. Daphne Bussink-Voorend & Jeannine L. A. Hautvast & Lisa Vandeberg & Olga Visser & Marlies E. J. L. Hulscher, 2022. "A systematic literature review to clarify the concept of vaccine hesitancy," Nature Human Behaviour, Nature, vol. 6(12), pages 1634-1648, December.
    12. Sarah C Klain & Paige Olmsted & Kai M A Chan & Terre Satterfield, 2017. "Relational values resonate broadly and differently than intrinsic or instrumental values, or the New Ecological Paradigm," PLOS ONE, Public Library of Science, vol. 12(8), pages 1-21, August.
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