IDEAS home Printed from https://ideas.repec.org/a/nat/nathum/v6y2022i12d10.1038_s41562-022-01431-6.html
   My bibliography  Save this article

A systematic literature review to clarify the concept of vaccine hesitancy

Author

Listed:
  • Daphne Bussink-Voorend

    (Radboud Institute for Health Sciences, Primary and Community Care)

  • Jeannine L. A. Hautvast

    (Radboud Institute for Health Sciences, Primary and Community Care)

  • Lisa Vandeberg

    (Radboud University)

  • Olga Visser

    (Radboud Institute for Health Sciences, Primary and Community Care)

  • Marlies E. J. L. Hulscher

    (Radboud Institute for Health Sciences, IQ Healthcare)

Abstract

Vaccine hesitancy (VH) is considered a top-10 global health threat. The concept of VH has been described and applied inconsistently. This systematic review aims to clarify VH by analysing how it is operationalized. We searched PubMed, Embase and PsycINFO databases on 14 January 2022. We selected 422 studies containing operationalizations of VH for inclusion. One limitation is that studies of lower quality were not excluded. Our qualitative analysis reveals that VH is conceptualized as involving (1) cognitions or affect, (2) behaviour and (3) decision making. A wide variety of methods have been used to measure VH. Our findings indicate the varied and confusing use of the term VH, leading to an impracticable concept. We propose that VH should be defined as a state of indecisiveness regarding a vaccination decision.

Suggested Citation

  • Daphne Bussink-Voorend & Jeannine L. A. Hautvast & Lisa Vandeberg & Olga Visser & Marlies E. J. L. Hulscher, 2022. "A systematic literature review to clarify the concept of vaccine hesitancy," Nature Human Behaviour, Nature, vol. 6(12), pages 1634-1648, December.
    • Handle: RePEc:nat:nathum:v:6:y:2022:i:12:d:10.1038_s41562-022-01431-6
    DOI: 10.1038/s41562-022-01431-6
    as

    Download full text from publisher

    File URL: https://www.nature.com/articles/s41562-022-01431-6
    File Function: Abstract
    Download Restriction: Access to the full text of the articles in this series is restricted.
    File URL: https://libkey.io/10.1038/s41562-022-01431-6?utm_source=ideas
    LibKey link: if access is restricted and if your library uses this service, LibKey will redirect you to where you can use your library subscription to access this item
    ---><---

    As the access to this document is restricted, you may want to search for a different version of it.

    References listed on IDEAS

    as
    1. Agnessa Kozak & Albert Nienhaus, 2021. "COVID-19 Vaccination: Status and Willingness to Be Vaccinated among Employees in Health and Welfare Care in Germany," IJERPH, MDPI, vol. 18(13), pages 1-14, June.
    2. Jumana Alibrahim & Abdelmoneim Awad, 2021. "COVID-19 Vaccine Hesitancy among the Public in Kuwait: A Cross-Sectional Survey," IJERPH, MDPI, vol. 18(16), pages 1-21, August.
    3. Katarzyna T. Bolsewicz & Maryke S. Steffens & Bianca Bullivant & Catherine King & Frank Beard, 2021. "“To Protect Myself, My Friends, Family, Workmates and Patients …and to Play My Part”: COVID-19 Vaccination Perceptions among Health and Aged Care Workers in New South Wales, Australia," IJERPH, MDPI, vol. 18(17), pages 1-13, August.
    4. Rossen, Isabel & Hurlstone, Mark J. & Dunlop, Patrick D. & Lawrence, Carmen, 2019. "Accepters, fence sitters, or rejecters: Moral profiles of vaccination attitudes," Social Science & Medicine, Elsevier, vol. 224(C), pages 23-27.
    5. Jamie Murphy & Frédérique Vallières & Richard P. Bentall & Mark Shevlin & Orla McBride & Todd K. Hartman & Ryan McKay & Kate Bennett & Liam Mason & Jilly Gibson-Miller & Liat Levita & Anton P. Martine, 2021. "Psychological characteristics associated with COVID-19 vaccine hesitancy and resistance in Ireland and the United Kingdom," Nature Communications, Nature, vol. 12(1), pages 1-15, December.
    6. Hyun Kyung Park & Ji Hye Ham & Deok Hyun Jang & Jin Yong Lee & Won Mo Jang, 2021. "Political Ideologies, Government Trust, and COVID-19 Vaccine Hesitancy in South Korea: A Cross-Sectional Survey," IJERPH, MDPI, vol. 18(20), pages 1-9, October.
    7. Mostafa Saidur Rahim Khan & Somtip Watanapongvanich & Yoshihiko Kadoya, 2021. "COVID-19 Vaccine Hesitancy among the Younger Generation in Japan," IJERPH, MDPI, vol. 18(21), pages 1-17, November.
    8. Avnika B. Amin & Robert A. Bednarczyk & Cara E. Ray & Kala J. Melchiori & Jesse Graham & Jeffrey R. Huntsinger & Saad B. Omer, 2017. "Association of moral values with vaccine hesitancy," Nature Human Behaviour, Nature, vol. 1(12), pages 873-880, December.
    9. Hornsey, Matthew J. & Lobera, Josep & Díaz-Catalán, Celia, 2020. "Vaccine hesitancy is strongly associated with distrust of conventional medicine, and only weakly associated with trust in alternative medicine," Social Science & Medicine, Elsevier, vol. 255(C).
    10. Milošević Đorđević, J. & Mari, S. & Vdović, M. & Milošević, A., 2021. "Links between conspiracy beliefs, vaccine knowledge, and trust: Anti-vaccine behavior of Serbian adults," Social Science & Medicine, Elsevier, vol. 277(C).
    11. Majdi M Sabahelzain & Eve Dubé & Mohamed Moukhyer & Heidi J Larson & Bart van den Borne & Hans Bosma, 2020. "Psychometric properties of the adapted measles vaccine hesitancy scale in Sudan," PLOS ONE, Public Library of Science, vol. 15(8), pages 1-12, August.
    12. Deml, Michael J. & Buhl, Andrea & Notter, Julia & Kliem, Paulina & Huber, Benedikt M. & Pfeiffer, Constanze & Burton-Jeangros, Claudine & Tarr, Philip E., 2020. "‘Problem patients and physicians’ failures': What it means for doctors to counsel vaccine hesitant patients in Switzerland," Social Science & Medicine, Elsevier, vol. 255(C).
    13. Martinelli, Mauro & Veltri, Giuseppe Alessandro, 2021. "Do cognitive styles affect vaccine hesitancy? A dual-process cognitive framework for vaccine hesitancy and the role of risk perceptions," Social Science & Medicine, Elsevier, vol. 289(C).
    14. Carmina Castellano-Tejedor & María Torres-Serrano & Andrés Cencerrado, 2021. "Unveiling Associations of COVID-19 Vaccine Acceptance, Hesitancy, and Resistance: A Cross-Sectional Community-Based Adult Survey," IJERPH, MDPI, vol. 18(23), pages 1-16, November.
    15. Matthew J Page & Joanne E McKenzie & Patrick M Bossuyt & Isabelle Boutron & Tammy C Hoffmann & Cynthia D Mulrow & Larissa Shamseer & Jennifer M Tetzlaff & Elie A Akl & Sue E Brennan & Roger Chou & Jul, 2021. "The PRISMA 2020 statement: An updated guideline for reporting systematic reviews," PLOS Medicine, Public Library of Science, vol. 18(3), pages 1-15, March.
    Full references (including those not matched with items on IDEAS)

    Most related items

    These are the items that most often cite the same works as this one and are cited by the same works as this one.
    1. Acar-Burkay, Sinem & Cristian, Daniela-Carmen, 2022. "Cognitive underpinnings of COVID-19 vaccine hesitancy," Social Science & Medicine, Elsevier, vol. 301(C).
    2. Callaghan, Timothy & Motta, Matthew & Sylvester, Steven & Lunz Trujillo, Kristin & Blackburn, Christine Crudo, 2019. "Parent psychology and the decision to delay childhood vaccination," Social Science & Medicine, Elsevier, vol. 238(C), pages 1-1.
    3. Amanda Hudson & William J. Montelpare, 2021. "Predictors of Vaccine Hesitancy: Implications for COVID-19 Public Health Messaging," IJERPH, MDPI, vol. 18(15), pages 1-14, July.
    4. Schmidtke, Kelly Ann & Kudrna, Laura & Noufaily, Angela & Stallard, Nigel & Skrybant, Magdalena & Russell, Samantha & Clarke, Aileen, 2022. "Evaluating the relationship between moral values and vaccine hesitancy in Great Britain during the COVID-19 pandemic: A cross-sectional survey," Social Science & Medicine, Elsevier, vol. 308(C).
    5. Huang, Qian & Gilkey, Melissa B. & Thompson, Peyton & Grabert, Brigid K. & Dailey, Susan Alton & Brewer, Noel T., 2022. "Explaining higher Covid-19 vaccination among some US primary care professionals," Social Science & Medicine, Elsevier, vol. 301(C).
    6. Gary D. Sherman & Beth Vallen & Stacey R. Finkelstein & Paul M. Connell & Wendy Attaya Boland & Kristen Feemster, 2021. "When taking action means accepting responsibility: Omission bias predicts parents' reluctance to vaccinate due to greater anticipated culpability for negative side effects," Journal of Consumer Affairs, Wiley Blackwell, vol. 55(4), pages 1660-1681, December.
    7. Trisha Harjani & Hongwei He & Melody Manchi Chao, 2024. "The Moral Foundations of Vaccine Passports," Journal of Business Ethics, Springer, vol. 190(1), pages 93-121, February.
    8. Kobayashi, Yoshiharu & Howell, Christopher & Heinrich, Tobias & Motta, Matthew, 2022. "Investigating how historical legacies of militarized violence can motivate COVID-19 vaccine hesitancy: Evidence from global dyadic survey," Social Science & Medicine, Elsevier, vol. 311(C).
    9. Giulietti, Corrado & Vlassopoulos, Michael & Zenou, Yves, 2021. "When Reality Bites: Local Deaths and Vaccine Take-Up," GLO Discussion Paper Series 999, Global Labor Organization (GLO).
    10. Boglárka Anna Éliás & Attila Jámbor, 2021. "Food Security and COVID-19: A Systematic Review of the First-Year Experience," Sustainability, MDPI, vol. 13(9), pages 1-18, May.
    11. Cala, Anggie & Maturana-Córdoba, Aymer & Soto-Verjel, Joseph, 2023. "Exploring the pretreatments' influence on pressure reverse osmosis: PRISMA review," Renewable and Sustainable Energy Reviews, Elsevier, vol. 188(C).
    12. Ming Shan & Yu-Shan Li & Bon-Gang Hwang & Jia-En Chua, 2021. "Productivity Metrics and Its Implementations in Construction Projects: A Case Study of Singapore," Sustainability, MDPI, vol. 13(21), pages 1-19, November.
    13. Susca, T. & Zanghirella, F. & Colasuonno, L. & Del Fatto, V., 2022. "Effect of green wall installation on urban heat island and building energy use: A climate-informed systematic literature review," Renewable and Sustainable Energy Reviews, Elsevier, vol. 159(C).
    14. Alexander P. L. Martindale & Benjamin Ng & Victoria Ngai & Aditya U. Kale & Lavinia Ferrante di Ruffano & Robert M. Golub & Gary S. Collins & David Moher & Melissa D. McCradden & Lauren Oakden-Rayner , 2024. "Concordance of randomised controlled trials for artificial intelligence interventions with the CONSORT-AI reporting guidelines," Nature Communications, Nature, vol. 15(1), pages 1-11, December.
    15. Gizéh Rangel-de Lázaro & Josep M. Duart, 2023. "You Can Handle, You Can Teach It: Systematic Review on the Use of Extended Reality and Artificial Intelligence Technologies for Online Higher Education," Sustainability, MDPI, vol. 15(4), pages 1-23, February.
    16. Deniz Dutz & Ingrid Huitfeldt & Santiago Lacouture & Magne Mogstad & Alexander Torgovitsky & Winnie van Dijk, 2021. "Selection in Surveys," NBER Working Papers 29549, National Bureau of Economic Research, Inc.
      • Deniz Dutz & Ingrid Huitfeldt & Santiago Lacouture & Magne Mogstad & Alexander Torgovitsky & Winnie van Dijk, 2021. "Selection in Surveys," Discussion Papers 971, Statistics Norway, Research Department.
    17. Ellen Busink & Dana Kendzia & Fatih Kircelli & Sophie Boeger & Jovana Petrovic & Helen Smethurst & Stephen Mitchell & Christian Apel, 2023. "A systematic review of the cost-effectiveness of renal replacement therapies, and consequences for decision-making in the end-stage renal disease treatment pathway," The European Journal of Health Economics, Springer;Deutsche Gesellschaft für Gesundheitsökonomie (DGGÖ), vol. 24(3), pages 377-392, April.
    18. Aleksandar S. Mojašević & Dejan Vučetić & Jelena Vučković & Stefan Stefanović, 2022. "Behavioral Approach to the COVID-19 Vaccination Policy: An Empirical Study in Serbia," Sustainability, MDPI, vol. 14(17), pages 1-19, August.
    19. Wang, Nan & Wang, Julian & Feng, Yanxiao, 2022. "Systematic review: Acute thermal effects of artificial light in the daytime," Renewable and Sustainable Energy Reviews, Elsevier, vol. 165(C).
    20. Tania Mateos-Blanco & Encarnación Sánchez‐Lissen & Inés Gil‐Jaurena & Clara Romero‐Pérez, 2022. "Child‐Led Participation: A Scoping Review of Empirical Studies," Social Inclusion, Cogitatio Press, vol. 10(2), pages 32-42.

    More about this item

    Statistics

    Access and download statistics

    Corrections

    All material on this site has been provided by the respective publishers and authors. You can help correct errors and omissions. When requesting a correction, please mention this item's handle: RePEc:nat:nathum:v:6:y:2022:i:12:d:10.1038_s41562-022-01431-6. See general information about how to correct material in RePEc.

    If you have authored this item and are not yet registered with RePEc, we encourage you to do it here. This allows to link your profile to this item. It also allows you to accept potential citations to this item that we are uncertain about.

    If CitEc recognized a bibliographic reference but did not link an item in RePEc to it, you can help with this form .

    If you know of missing items citing this one, you can help us creating those links by adding the relevant references in the same way as above, for each refering item. If you are a registered author of this item, you may also want to check the "citations" tab in your RePEc Author Service profile, as there may be some citations waiting for confirmation.

    For technical questions regarding this item, or to correct its authors, title, abstract, bibliographic or download information, contact: Sonal Shukla or Springer Nature Abstracting and Indexing (email available below). General contact details of provider: http://www.nature.com .

    Please note that corrections may take a couple of weeks to filter through the various RePEc services.

    IDEAS is a RePEc service. RePEc uses bibliographic data supplied by the respective publishers.