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Global sensitivity analysis of the harmonized Lemna model

Author

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  • Guisnet, Chloé
  • Reichenberger, Stefan
  • García, Elena Alonso
  • Voss, Frank

Abstract

Mechanistic effect modelling is becoming increasingly important for environmental risk assessment in the framework of pesticide authorization. For instance, the European Food Safety Authority (EFSA) has judged the model for the aquatic macrophyte test organism Lemna as “ready for use.” Nevertheless, national regulatory authorities are still hesitant to accept mechanistic effect modelling studies.

Suggested Citation

  • Guisnet, Chloé & Reichenberger, Stefan & García, Elena Alonso & Voss, Frank, 2025. "Global sensitivity analysis of the harmonized Lemna model," Ecological Modelling, Elsevier, vol. 501(C).
    • Handle: RePEc:eee:ecomod:v:501:y:2025:i:c:s0304380024004046
    DOI: 10.1016/j.ecolmodel.2024.111016
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    References listed on IDEAS

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    1. Jager, Tjalling & Goussen, Benoit & Gergs, André, 2023. "Using the standard DEB animal model for toxicokinetic-toxicodynamic analysis," Ecological Modelling, Elsevier, vol. 475(C).
    2. Schmitt, Walter & Bruns, Eric & Dollinger, Margit & Sowig, Peter, 2013. "Mechanistic TK/TD-model simulating the effect of growth inhibitors on Lemna populations," Ecological Modelling, Elsevier, vol. 255(C), pages 1-10.
    3. Ciric, C. & Ciffroy, P. & Charles, S., 2012. "Use of sensitivity analysis to identify influential and non-influential parameters within an aquatic ecosystem model," Ecological Modelling, Elsevier, vol. 246(C), pages 119-130.
    4. Shang, Xiaobing & Wang, Lipeng & Fang, Hai & Lu, Lingyun & Zhang, Zhi, 2024. "Active Learning of Ensemble Polynomial Chaos Expansion Method for Global Sensitivity Analysis," Reliability Engineering and System Safety, Elsevier, vol. 249(C).
    5. Andrea Saltelli, 2002. "Sensitivity Analysis for Importance Assessment," Risk Analysis, John Wiley & Sons, vol. 22(3), pages 579-590, June.
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