IDEAS home Printed from https://ideas.repec.org/a/eee/csdana/v54y2010i1p173-184.html

Approximate conditional inference in mixed-effects models with binary data

Author

Listed:
  • Lee, Woojoo
  • Shi, Jian Qing
  • Lee, Youngjo

Abstract

The conditional likelihood approach is a sensible choice for a hierarchical logistic regression model or other generalized regression models with binary data. However, its heavy computational burden limits its use, especially for the related mixed-effects model. A modified profile likelihood is used as an accurate approximation to conditional likelihood, and then the use of two methods for inferences for the hierarchical generalized regression models with mixed effects is proposed. One is based on a hierarchical likelihood and Laplace approximation method, and the other is based on a Markov chain Monte Carlo EM algorithm. The methods are applied to a meta-analysis model for trend estimation and the model for multi-arm trials. A simulation study is conducted to illustrate the performance of the proposed methods.

Suggested Citation

  • Lee, Woojoo & Shi, Jian Qing & Lee, Youngjo, 2010. "Approximate conditional inference in mixed-effects models with binary data," Computational Statistics & Data Analysis, Elsevier, vol. 54(1), pages 173-184, January.
    • Handle: RePEc:eee:csdana:v:54:y:2010:i:1:p:173-184
    as

    Download full text from publisher

    File URL: http://www.sciencedirect.com/science/article/pii/S0167-9473(09)00270-9
    Download Restriction: Full text for ScienceDirect subscribers only.
    ---><---

    As the access to this document is restricted, you may want to

    for a different version of it.

    References listed on IDEAS

    as
    1. Jian Qing Shi & John Copas, 2002. "Publication bias and meta‐analysis for 2×2 tables: an average Markov chain Monte Carlo EM algorithm," Journal of the Royal Statistical Society Series B, Royal Statistical Society, vol. 64(2), pages 221-236, May.
    2. J. G. Liao, 1999. "A Hierarchical Bayesian Model for Combining Multiple 2 × 2 Tables Using Conditional Likelihoods," Biometrics, The International Biometric Society, vol. 55(1), pages 268-272, March.
    3. N. Sartori, 2003. "Modified profile likelihoods in models with stratum nuisance parameters," Biometrika, Biometrika Trust, vol. 90(3), pages 533-549, September.
    4. Noh, Maengseok & Lee, Youngjo, 2007. "REML estimation for binary data in GLMMs," Journal of Multivariate Analysis, Elsevier, vol. 98(5), pages 896-915, May.
    5. Shih, Joanna H. & Lu, Shou-En, 2009. "Semiparametric estimation of a nested random effects model for the analysis of multi-level clustered failure time data," Computational Statistics & Data Analysis, Elsevier, vol. 53(11), pages 3864-3871, September.
    6. Ruggero Bellio & Nicola Sartori, 2003. "Extending conditional likelihood in models for stratified binary data," Statistical Methods & Applications, Springer;Società Italiana di Statistica, vol. 12(2), pages 121-132, December.
    Full references (including those not matched with items on IDEAS)

    Most related items

    These are the items that most often cite the same works as this one and are cited by the same works as this one.
    1. Cavit Pakel & Neil Shephard & Kevin Sheppard & Robert F. Engle, 2021. "Fitting Vast Dimensional Time-Varying Covariance Models," Journal of Business & Economic Statistics, Taylor & Francis Journals, vol. 39(3), pages 652-668, July.
    2. Cavit Pakel & Neil Shephard & Kevin Sheppard, 2009. "Nuisance parameters, composite likelihoods and a panel of GARCH models," OFRC Working Papers Series 2009fe03, Oxford Financial Research Centre.
    3. repec:spo:wpmain:info:hdl:2441/eu4vqp9ompqllr09ij4j0h0h1 is not listed on IDEAS
    4. Dhaene, Geert & Jochmans, Koen, 2016. "Likelihood Inference In An Autoregression With Fixed Effects," Econometric Theory, Cambridge University Press, vol. 32(5), pages 1178-1215, October.
    5. Pakel, Cavit, 2019. "Bias reduction in nonlinear and dynamic panels in the presence of cross-section dependence," Journal of Econometrics, Elsevier, vol. 213(2), pages 459-492.
    6. Johannes S. Kunz & Kevin E. Staub & Rainer Winkelmann, 2021. "Predicting individual effects in fixed effects panel probit models," Journal of the Royal Statistical Society Series A, Royal Statistical Society, vol. 184(3), pages 1109-1145, July.
    7. Xuan Leng & Jiaming Mao & Yutao Sun, 2023. "Debiased Inference for Dynamic Nonlinear Panels with Multi-dimensional Heterogeneities," Papers 2305.03134, arXiv.org, revised Jan 2026.
    8. Han, Jeongseop & Lee, Youngjo, 2024. "Enhanced Laplace approximation," Journal of Multivariate Analysis, Elsevier, vol. 202(C).
    9. Geert Dhaene & Koen Jochmans, 2015. "Profile-score adjustments for incidental-parameter problems," Sciences Po publications info:hdl:2441/323dml6suu9, Sciences Po.
    10. Jochmans, Koen & Weidner, Martin, 2024. "Inference On A Distribution From Noisy Draws," Econometric Theory, Cambridge University Press, vol. 40(1), pages 60-97, February.
    11. J. G. Liao & Duanping Liao & Arthur Berg, 2016. "Calibrated Bayes Factors in Assessing Genetic Association Models," The American Statistician, Taylor & Francis Journals, vol. 70(3), pages 250-256, July.
    12. Yanbo Tang & Nancy Reid, 2020. "Modified likelihood root in high dimensions," Journal of the Royal Statistical Society Series B, Royal Statistical Society, vol. 82(5), pages 1349-1369, December.
    13. Yu, Dalei & Yau, Kelvin K.W., 2012. "Conditional Akaike information criterion for generalized linear mixed models," Computational Statistics & Data Analysis, Elsevier, vol. 56(3), pages 629-644.
    14. Joe, Harry, 2008. "Accuracy of Laplace approximation for discrete response mixed models," Computational Statistics & Data Analysis, Elsevier, vol. 52(12), pages 5066-5074, August.
    15. Schumann, Martin & Severini, Thomas A. & Tripathi, Gautam, 2023. "The role of score and information bias in panel data likelihoods," Journal of Econometrics, Elsevier, vol. 235(2), pages 1215-1238.
    16. Asma Saleh, 2024. "Reduced bias estimation of the log odds ratio," Statistical Papers, Springer, vol. 65(8), pages 5293-5331, October.
    17. Koen Jochmans, 2018. "Semiparametric Analysis of Network Formation," Journal of Business & Economic Statistics, Taylor & Francis Journals, vol. 36(4), pages 705-713, October.
    18. Sumanta Adhya & Tathagata Banerjee & Gaurangadeb Chattopadhyay, 2012. "Inference on finite population categorical response: nonparametric regression-based predictive approach," AStA Advances in Statistical Analysis, Springer;German Statistical Society, vol. 96(1), pages 69-98, January.
    19. Martellosio, Federico & Hillier, Grant, 2020. "Adjusted QMLE for the spatial autoregressive parameter," Journal of Econometrics, Elsevier, vol. 219(2), pages 488-506.
    20. Meza, Cristian & Jaffrézic, Florence & Foulley, Jean-Louis, 2009. "Estimation in the probit normal model for binary outcomes using the SAEM algorithm," Computational Statistics & Data Analysis, Elsevier, vol. 53(4), pages 1350-1360, February.
    21. Sik-Yum Lee & Xin-Yuan Song, 2007. "A Unified Maximum Likelihood Approach for Analyzing Structural Equation Models With Missing Nonstandard Data," Sociological Methods & Research, , vol. 35(3), pages 352-381, February.

    More about this item

    Statistics

    Access and download statistics

    Corrections

    All material on this site has been provided by the respective publishers and authors. You can help correct errors and omissions. When requesting a correction, please mention this item's handle: RePEc:eee:csdana:v:54:y:2010:i:1:p:173-184. See general information about how to correct material in RePEc.

    If you have authored this item and are not yet registered with RePEc, we encourage you to do it here. This allows to link your profile to this item. It also allows you to accept potential citations to this item that we are uncertain about.

    If CitEc recognized a bibliographic reference but did not link an item in RePEc to it, you can help with this form .

    If you know of missing items citing this one, you can help us creating those links by adding the relevant references in the same way as above, for each refering item. If you are a registered author of this item, you may also want to check the "citations" tab in your RePEc Author Service profile, as there may be some citations waiting for confirmation.

    For technical questions regarding this item, or to correct its authors, title, abstract, bibliographic or download information, contact: Catherine Liu (email available below). General contact details of provider: http://www.elsevier.com/locate/csda .

    Please note that corrections may take a couple of weeks to filter through the various RePEc services.

    IDEAS is a RePEc service. RePEc uses bibliographic data supplied by the respective publishers.