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A Frailty-Model-Based Approach to Estimating the Age-Dependent Penetrance Function of Candidate Genes Using Population-Based Case-Control Study Designs: An Application to Data on the BRCA1 Gene

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  • Lu Chen
  • Li Hsu
  • Kathleen Malone

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  • Lu Chen & Li Hsu & Kathleen Malone, 2009. "A Frailty-Model-Based Approach to Estimating the Age-Dependent Penetrance Function of Candidate Genes Using Population-Based Case-Control Study Designs: An Application to Data on the BRCA1 Gene," Biometrics, The International Biometric Society, vol. 65(4), pages 1105-1114, December.
  • Handle: RePEc:bla:biomet:v:65:y:2009:i:4:p:1105-1114
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    File URL: http://hdl.handle.net/10.1111/j.1541-0420.2008.01184.x
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    References listed on IDEAS

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    1. N. E. Breslow & N. Chatterjee, 1999. "Design and analysis of two‐phase studies with binary outcome applied to Wilms tumour prognosis," Journal of the Royal Statistical Society Series C, Royal Statistical Society, vol. 48(4), pages 457-468.
    2. Li Hsu & Lu Chen & Malka Gorfine & Kathleen Malone, 2004. "Semiparametric Estimation of Marginal Hazard Function from Case–Control Family Studies," Biometrics, The International Biometric Society, vol. 60(4), pages 936-944, December.
    3. Nilanjan Chatterjee & Zeynep Kalaylioglu & Joanna H. Shih & Mitchell H. Gail, 2006. "Case–Control and Case-Only Designs with Genotype and Family History Data: Estimating Relative Risk, Residual Familial Aggregation, and Cumulative Risk," Biometrics, The International Biometric Society, vol. 62(1), pages 36-48, March.
    4. Nilanjan Chatterjee & Sholom Wacholder, 2001. "A Marginal Likelihood Approach for Estimating Penetrance from Kin‐Cohort Designs," Biometrics, The International Biometric Society, vol. 57(1), pages 245-252, March.
    5. D. Zeng & D. Y. Lin, 2007. "Maximum likelihood estimation in semiparametric regression models with censored data," Journal of the Royal Statistical Society Series B, Royal Statistical Society, vol. 69(4), pages 507-564, September.
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    Cited by:

    1. Basile, Luigi Jesus & Carbonara, Nunzia & Pellegrino, Roberta & Panniello, Umberto, 2023. "Business intelligence in the healthcare industry: The utilization of a data-driven approach to support clinical decision making," Technovation, Elsevier, vol. 120(C).

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