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A relational approach to knowledge spillovers in biotech. Network structures as drivers of inter-organizational citation patterns

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  • Ron Boschma

    ()

  • Pierre-Alexandre Balland

    ()

  • Dieter Kogler

    ()

Abstract

In this paper, we analyze the geography of knowledge spillovers in biotech by investigating the way in which knowledge ties are organized. Following a relational account on knowledge spillovers, we depict knowledge networks as complex evolving structures that build on pre-existing knowledge and previously formed ties. In economic geography, there is still little understanding of how structural network forces (like preferential attachment and closure) shape the structure and formation of knowledge spillover networks in space. Our study investigates the knowledge spillover networks of biotech firms by means of inter-organizational citation patterns based on USPTO biotech patents in the years 2008-2010. Using a Stochastic Actor-Oriented Model (SAOM), we explain the driving forces behind the decision of actors to cite patents produced by other actors. Doing so, we address directly the endogenous forces of knowledge dynamics.

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Bibliographic Info

Paper provided by Utrecht University, Section of Economic Geography in its series Papers in Evolutionary Economic Geography (PEEG) with number 1120.

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Length: 20 pages
Date of creation: Dec 2011
Date of revision: Dec 2011
Handle: RePEc:egu:wpaper:1120

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Related research

Keywords: knowledge spillovers; network structure; patent citations; biotech; proximity;

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References

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  1. Zucker, Lynne G & Darby, Michael R & Brewer, Marilynn B, 1998. "Intellectual Human Capital and the Birth of U.S. Biotechnology Enterprises," American Economic Review, American Economic Association, vol. 88(1), pages 290-306, March.
  2. Stefano Breschi & Francesco Lissoni, 2001. "Knowledge spillovers and local innovation systems: a critical survey," LIUC Papers in Economics 84, Cattaneo University (LIUC).
  3. Jarno Hoekman & Koen Frenken & Frank Oort, 2009. "The geography of collaborative knowledge production in Europe," The Annals of Regional Science, Springer, vol. 43(3), pages 721-738, September.
  4. Ejermo, Olof & Karlsson, Charlie, 2005. "Interregional Inventor Networks as Studied by Patent Co-inventorships," CIRCLE Electronic Working Papers 2005/11, Lund University, CIRCLE - Center for Innovation, Research and Competences in the Learning Economy.
  5. Stefano Breschi & Francesco Lissoni, 2003. "Mobility and Social Networks: Localised Knowledge Spillovers Revisited," KITeS Working Papers 142, KITeS, Centre for Knowledge, Internationalization and Technology Studies, Universita' Bocconi, Milano, Italy, revised Mar 2003.
  6. Gomes-Casseres, Benjamin & Hagedoorn, John & Jaffe, Adam B., 2006. "Do alliances promote knowledge flows?," Journal of Financial Economics, Elsevier, vol. 80(1), pages 5-33, April.
  7. Mario A. Maggioni & Mario Nosvelli & T. Erika Uberti, 2006. "Space Vs. Networks in the Geography of Innovation: A European Analysis," Working Papers 2006.153, Fondazione Eni Enrico Mattei.
  8. M. Ozman, 2009. "Inter-firm networks and innovation: a survey of literature," Economics of Innovation and New Technology, Taylor & Francis Journals, vol. 18(1), pages 39-67.
  9. Luigi Orsenigo & Fabio Pammolli & Massimo Riccaboni & Andrea Bonaccorsi & Giuseppe Turchetti, 1997. "The Evolution of Knowledge and the Dynamics of an Industry Network," Journal of Management and Governance, Springer, vol. 1(2), pages 147-175, June.
  10. Lynne G. Zucker & Michael R. Darby & Jeff S. Armstrong, 2003. "Commercializing knowledge: university science, knowledge capture and firm performance in biotechnology," Proceedings, Federal Reserve Bank of Dallas, issue Sep, pages 149-170.
  11. Pierre-Alexandre Balland & Mathijs De Vaan & Ron Boschma, 2013. "The dynamics of interfirm networks along the industry life cycle: The case of the global video game industry, 1987--2007," Journal of Economic Geography, Oxford University Press, vol. 13(5), pages 741-765, September.
  12. Hall, B. & Jaffe, A. & Trajtenberg, M., 2001. "The NBER Patent Citations Data File: Lessons, Insights and Methodological Tools," Papers 2001-29, Tel Aviv.
  13. Johannes Glückler, 2007. "Economic geography and the evolution of networks," Journal of Economic Geography, Oxford University Press, vol. 7(5), pages 619-634, September.
  14. John Cantwell & Grazia D. Santangelo, 2002. "special issue: The new geography of corporate research in Information and Communications Technology (ICT)," Journal of Evolutionary Economics, Springer, vol. 12(1), pages 163-197.
  15. Hans T. W. Frankort & John Hagedoorn & Wilko Letterie, 2012. "R&D partnership portfolios and the inflow of technological knowledge," Industrial and Corporate Change, Oxford University Press, vol. 21(2), pages 507-537, April.
  16. Elisa Giuliani, 2007. "The selective nature of knowledge networks in clusters: evidence from the wine industry," Journal of Economic Geography, Oxford University Press, vol. 7(2), pages 139-168, March.
  17. Stefano Breschi & Francesco Lissoni, 2006. "Mobility of inventors and the geography of knowledge spillovers. New evidence on US data," KITeS Working Papers 184, KITeS, Centre for Knowledge, Internationalization and Technology Studies, Universita' Bocconi, Milano, Italy, revised Oct 2006.
  18. Stefano Breschi & Francesco Lissoni, 2009. "Mobility of skilled workers and co-invention networks: an anatomy of localized knowledge flows," Journal of Economic Geography, Oxford University Press, vol. 9(4), pages 439-468, July.
  19. Kortum, Samuel & Lerner, Josh, 1999. "What is behind the recent surge in patenting?1," Research Policy, Elsevier, vol. 28(1), pages 1-22, January.
  20. Paul Almeida & Bruce Kogut, 1999. "Localization of Knowledge and the Mobility of Engineers in Regional Networks," Management Science, INFORMS, vol. 45(7), pages 905-917, July.
  21. Roderik Ponds & Frank van Oort & Koen Frenken, 2007. "The geographical and institutional proximity of research collaboration," Papers in Regional Science, Wiley Blackwell, vol. 86(3), pages 423-443, 08.
  22. Niosi, Jorge & Bas, Tomas G, 2001. " The Competencies of Regions--Canada's Clusters in Biotechnology," Small Business Economics, Springer, vol. 17(1-2), pages 31-42, Aug.-Sept.
  23. Pierre-Alexandre Balland, 2009. "Proximity and the Evolution of Collaboration Networks: Evidence from R&D Projects within the GNSS Industry," Papers in Evolutionary Economic Geography (PEEG) 0914, Utrecht University, Section of Economic Geography, revised Oct 2009.
  24. Elisa Giuliani, 2010. "Network dynamics in regional clusters: The perspective of an emerging economy," Papers in Evolutionary Economic Geography (PEEG) 1014, Utrecht University, Section of Economic Geography, revised Oct 2010.
  25. Johannes Gluckler, 2007. "Economic Geography and the Evolution of Networks," Papers in Evolutionary Economic Geography (PEEG) 0704, Utrecht University, Section of Economic Geography, revised Apr 2007.
  26. Ron Boschma, 2005. "Proximity and Innovation: A Critical Assessment," Regional Studies, Taylor & Francis Journals, vol. 39(1), pages 61-74.
  27. Balconi, Margherita & Breschi, Stefano & Lissoni, Francesco, 2004. "Networks of inventors and the role of academia: an exploration of Italian patent data," Research Policy, Elsevier, vol. 33(1), pages 127-145, January.
  28. Ron Boschma & Koen Frenken, 2009. "The Spatial Evolution of Innovation Networks: A Proximity Perspective," Papers in Evolutionary Economic Geography (PEEG) 0905, Utrecht University, Section of Economic Geography, revised Jun 2009.
  29. Sorenson, Olav & Rivkin, Jan W. & Fleming, Lee, 2006. "Complexity, networks and knowledge flow," Research Policy, Elsevier, vol. 35(7), pages 994-1017, September.
  30. Acs, Zoltan J. & Anselin, Luc & Varga, Attila, 2002. "Patents and innovation counts as measures of regional production of new knowledge," Research Policy, Elsevier, vol. 31(7), pages 1069-1085, September.
  31. Juan Alcácer & Wilbur Chung, 2007. "Location Strategies and Knowledge Spillovers," Management Science, INFORMS, vol. 53(5), pages 760-776, May.
  32. Anne Ter Wal & Ron Boschma, 2009. "Applying social network analysis in economic geography: framing some key analytic issues," The Annals of Regional Science, Springer, vol. 43(3), pages 739-756, September.
  33. Michelle Gittelman & Bruce Kogut, 2003. "Does Good Science Lead to Valuable Knowledge? Biotechnology Firms and the Evolutionary Logic of Citation Patterns," Management Science, INFORMS, vol. 49(4), pages 366-382, April.
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Cited by:
  1. Tom Broekel & Pierre-Alexandre Balland & Martijn Burger & Frank van Oort, 2013. "Modeling Knowledge Networks in Economic Geography: A Discussion of Four Empirical Strategies," Papers in Evolutionary Economic Geography (PEEG) 1325, Utrecht University, Section of Economic Geography, revised Dec 2013.

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