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The Optimal Control of Infectious Diseases via Prevention and Treatment

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  • Rowthorn, R.
  • Toxvaerd, F.M.O

Abstract

This paper characterizes the optimal control of a recurrent infectious disease through the use of treatment and preventive non-pharmaceutical interventions such as social distancing and curfews. We find that under centralized decision making, treatment induces positive destabilizing feedback effects, while prevention induces negative stabilizing feedback effects. While optimal treatment pushes prevalence towards the extremes, optimal prevention pushes it towards interior solutions. As a result, the dynamic system may admit multiple steady states and the optimal policy may be history dependent. We find that steady state prevalence levels in decentralized equilibrium must be equal to or higher than the socially optimal levels. The differences between the equilibrium outcome and the social optimum derive from the existence of a pure externality effect and a separate smallness effect due to individuals being small. Last, we derive two separate corrective subsidy schemes that decentralize the socially optimal outcome, namely subsidies to prevention and treatment and a tax on the infected.

Suggested Citation

  • Rowthorn, R. & Toxvaerd, F.M.O, 2020. "The Optimal Control of Infectious Diseases via Prevention and Treatment," Cambridge Working Papers in Economics 2027, Faculty of Economics, University of Cambridge.
  • Handle: RePEc:cam:camdae:2027
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    1. Klein, Eili & Laxminarayan, Ramanan & Smith, David L. & Gilligan, Christopher A., 2007. "Economic incentives and mathematical models of disease," Environment and Development Economics, Cambridge University Press, vol. 12(5), pages 707-732, October.
    2. Aadland David & Finnoff David C. & Huang Kevin X.D., 2013. "Syphilis Cycles," The B.E. Journal of Economic Analysis & Policy, De Gruyter, vol. 14(1), pages 297-348, June.
    3. Rubio, Santiago J. & Escriche, Luisa, 2001. "Strategic pigouvian taxation, stock externalities and polluting non-renewable resources," Journal of Public Economics, Elsevier, vol. 79(2), pages 297-313, February.
    4. Karl-Göran Mäler & Anastasios Xepapadeas & Aart de Zeeuw, 2003. "The Economics of Shallow Lakes," Environmental & Resource Economics, Springer;European Association of Environmental and Resource Economists, vol. 26(4), pages 603-624, December.
    5. Michael Kremer, Christopher M. Snyder & Christopher M. Snyder, 2013. "When Is Prevention More Profitable than Cure? The Impact of Time-Varying Consumer Heterogeneity - Working Paper 334," Working Papers 334, Center for Global Development.
    6. Rowthorn, Robert & Toxvaerd, Flavio, 2012. "The Optimal Control of Infectious Diseases via Prevention and Treatment," CEPR Discussion Papers 8925, C.E.P.R. Discussion Papers.
    7. Caputo,Michael R., 2005. "Foundations of Dynamic Economic Analysis," Cambridge Books, Cambridge University Press, number 9780521842723, January.
    8. Goenka, Aditya & Liu, Lin & Nguyen, Manh-Hung, 2014. "Infectious diseases and economic growth," Journal of Mathematical Economics, Elsevier, vol. 50(C), pages 34-53.
    9. Doris A. Behrens & Jonathan P. Caulkins & Gernot Tragler & Gustav Feichtinger, 2000. "Optimal Control of Drug Epidemics: Prevent and Treat---But Not at the Same Time?," Management Science, INFORMS, vol. 46(3), pages 333-347, March.
    10. Wagener, F. O. O., 2003. "Skiba points and heteroclinic bifurcations, with applications to the shallow lake system," Journal of Economic Dynamics and Control, Elsevier, vol. 27(9), pages 1533-1561, July.
    11. Herrmann, Markus & Gaudet, Gérard, 2009. "The economic dynamics of antibiotic efficacy under open access," Journal of Environmental Economics and Management, Elsevier, vol. 57(3), pages 334-350, May.
    12. Philipson, Tomas, 2000. "Economic epidemiology and infectious diseases," Handbook of Health Economics, in: A. J. Culyer & J. P. Newhouse (ed.), Handbook of Health Economics, edition 1, volume 1, chapter 33, pages 1761-1799, Elsevier.
    13. Farzin, Y. H., 1996. "Optimal pricing of environmental and natural resource use with stock externalities," Journal of Public Economics, Elsevier, vol. 62(1-2), pages 31-57, October.
    14. Goldman Steven Marc & Lightwood James, 2002. "Cost Optimization in the SIS Model of Infectious Disease with Treatment," The B.E. Journal of Economic Analysis & Policy, De Gruyter, vol. 2(1), pages 1-24, April.
    15. Michael Kremer & Christopher Snyder, 2013. "When is Prevention More Profitable than Cure?," CID Working Papers 252, Center for International Development at Harvard University.
    16. Goyal, Sanjeev & Vigier, Adrien, 2015. "Interaction, protection and epidemics," Journal of Public Economics, Elsevier, vol. 125(C), pages 64-69.
    17. Michael Kremer & Christopher M. Snyder, 2013. "When Is Prevention More Profitable than Cure? The Impact of Time-Varying Consumer Heterogeneity," NBER Working Papers 18862, National Bureau of Economic Research, Inc.
    18. Mark Gersovitz & Jeffrey S. Hammer, 2004. "The Economical Control of Infectious Diseases," Economic Journal, Royal Economic Society, vol. 114(492), pages 1-27, January.
    19. Flavio Toxvaerd, 2019. "Rational Disinhibition And Externalities In Prevention," International Economic Review, Department of Economics, University of Pennsylvania and Osaka University Institute of Social and Economic Research Association, vol. 60(4), pages 1737-1755, November.
    20. Toxvaerd, F. & Rowthorn, R., 2020. "On the Management of Population Immunity," Cambridge Working Papers in Economics 2080, Faculty of Economics, University of Cambridge.
    21. Anderson, Soren T. & Laxminarayan, Ramanan & Salant, Stephen W., 2012. "Diversify or focus? Spending to combat infectious diseases when budgets are tight," Journal of Health Economics, Elsevier, vol. 31(4), pages 658-675.
    22. Toxvaerd, Flavio, 2010. "Infection, Acquired Immunity and Externalities in Treatment," CEPR Discussion Papers 8111, C.E.P.R. Discussion Papers.
    23. Stéphane Mechoulan, 2007. "Market structure and communicable diseases," Canadian Journal of Economics, Canadian Economics Association, vol. 40(2), pages 468-492, May.
    24. Timothy C Reluga, 2010. "Game Theory of Social Distancing in Response to an Epidemic," PLOS Computational Biology, Public Library of Science, vol. 6(5), pages 1-9, May.
    25. Arrow, Kenneth J. & Kurz, Mordecai, 1969. "Optimal public investment policy and controllability with fixed private savings ratio," Journal of Economic Theory, Elsevier, vol. 1(2), pages 141-177, August.
    26. Laxminarayan, Ramanan & Brown, Gardner M., 2001. "Economics of Antibiotic Resistance: A Theory of Optimal Use," Journal of Environmental Economics and Management, Elsevier, vol. 42(2), pages 183-206, September.
    27. Geoffard, Pierre-Yves & Philipson, Tomas, 1996. "Rational Epidemics and Their Public Control," International Economic Review, Department of Economics, University of Pennsylvania and Osaka University Institute of Social and Economic Research Association, vol. 37(3), pages 603-624, August.
    28. Michael Kremer, 1996. "Integrating Behavioral Choice into Epidemiological Models of AIDS," The Quarterly Journal of Economics, President and Fellows of Harvard College, vol. 111(2), pages 549-573.
    29. Mark Gersovitz & Jeffrey S. Hammer, 2003. "Infectious Diseases, Public Policy, and the Marriage of Economics and Epidemiology," The World Bank Research Observer, World Bank, vol. 18(2), pages 129-157.
    30. Toxvaerd, F.M.O, 2020. "Equilibrium Social Distancing," Cambridge Working Papers in Economics 2021, Faculty of Economics, University of Cambridge.
    31. Fenichel, Eli P., 2013. "Economic considerations for social distancing and behavioral based policies during an epidemic," Journal of Health Economics, Elsevier, vol. 32(2), pages 440-451.
    32. Robert Halvorsen & David F. Layton (ed.), 2006. "Explorations in Environmental and Natural Resource Economics," Books, Edward Elgar Publishing, number 3697.
    33. Carol Y. Lin, 2008. "Modeling Infectious Diseases in Humans and Animals by KEELING, M. J. and ROHANI, P," Biometrics, The International Biometric Society, vol. 64(3), pages 993-993, September.
    34. Toxvaerd, Flavio, 2010. "Recurrent Infection and Externalities in Prevention," CEPR Discussion Papers 8112, C.E.P.R. Discussion Papers.
    35. W.A. Brock & D. Starrett, 2003. "Managing Systems with Non-convex Positive Feedback," Environmental & Resource Economics, Springer;European Association of Environmental and Resource Economists, vol. 26(4), pages 575-602, December.
    36. Michael Kremer, 1996. "Integrating Behavioral Choice into Epidemiological Models of the AIDS Epidemic," NBER Working Papers 5428, National Bureau of Economic Research, Inc.
    37. Brito, Dagobert L. & Sheshinski, Eytan & Intriligator, Michael D., 1991. "Externalities and compulsary vaccinations," Journal of Public Economics, Elsevier, vol. 45(1), pages 69-90, June.
    38. Tahvonen Olli & Kuuluvainen Jari, 1993. "Economic Growth, Pollution, and Renewable Resources," Journal of Environmental Economics and Management, Elsevier, vol. 24(2), pages 101-118, March.
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    More about this item

    Keywords

    Economic epidemiology; treatment; prevention; optimal and equilibrium policy mix; hysteresis; non-convex systems;
    All these keywords.

    JEL classification:

    • C73 - Mathematical and Quantitative Methods - - Game Theory and Bargaining Theory - - - Stochastic and Dynamic Games; Evolutionary Games
    • H20 - Public Economics - - Taxation, Subsidies, and Revenue - - - General
    • I18 - Health, Education, and Welfare - - Health - - - Government Policy; Regulation; Public Health

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