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Content
December 2026, Volume 17, Issue 1
- 1-21 Hundreds of cardiac MRI traits derived using 3D diffusion autoencoders share a common genetic architecture
by Sara Ometto & Soumick Chatterjee & Andrea Mario Vergani & Arianna Landini & Sodbo Sharapov & Edoardo Giacopuzzi & Alessia Visconti & Emanuele Bianchi & Federica Santonastaso & Emanuel M. Soda & Francesco Cisternino & Carlo Andrea Pivato & Francesca Ieva & Emanuele Di Angelantonio & Nicola Pirastu & Craig A. Glastonbury
- 1-21 Spatial transcriptomics reveals distinct cell type dynamics following opioid dependence in female mice with the common human μ-opioid receptor variant Oprm1 A118G
by Yihan Xie & Anna K. Leonard & Omar Guessoum & Kyle A. Windisch & Johnathan Schug & Hilana El-Mekkoussi & Adrienne Jo & D. Kacy Cullen & Klaus H. Kaestner & Julie A. Blendy
- 1-21 Sarcopenia promotes tumorigenesis by disrupting NOTCH-SDC2-regulated biogenesis of muscle-derived extracellular vesicles
by Kah Yong Goh & Wen Xing Lee & Qian Gou & Sze Mun Choy & Shi Chee Ong & Priya D. Gopal Krishnan & Huaxin Wang & Lewin Raymarc Roldan Turqueza & Qian Hui Tan & Kenon Chua & Shang Li & Jun Nishiyama & Nathan Harmston & Hong-Wen Tang
- 1-21 Combined targeted and epigenetic-based therapy enhances antitumor immunity by stabilizing GATA6-dependent MHCI expression in pancreatic ductal adenocarcinoma
by JuanFei Peng & JiaJin Yang & Georgia Antonopoulou & Rui Fang & Bikash Adhikari & Markus Vogt & Elmar Wolf & Chong Sun & Shangce Du & Laura Godfrey & Aayush Gupta & Marija Trajkovic-Arsic & Nicole Teichmann & Barbara T. Grünwald & Niklas Krebs & Katja Steiger & Carolin Mogler & Kristina Althoff & Xin Wang & Giovanni Giglio & Sven-Thorsten Liffers & Konstantinos Savvatakis & Rickmer Braren & Rita T. Lawlor & Aldo Scarpa & Diana Behrens & Karl S. Lang & Phyllis F. Cheung & Jens T. Siveke
- 1-21 Human CD24+ dental papilla cells are competent seed cells for dentin-pulp regeneration via BMP2/SIRT1 axis
by Cheng Liang & Zhi Liu & Jie Li & Cong Han & Yu Gao & Bohuai Zhou & Qiuyu Chen & Fei Bi & Chengcheng Liao & Weimin Wu & Tiantian Hu & Jingyi Zhang & Ding Bai & Yiping Chen & Zhonghan Li & Weidong Tian & Tian Chen
- 1-21 Blockage of autophagy causes severe skeletal muscle disruption in a mouse model for myofibrillar myopathy 6
by Kerstin Filippi & Kathrin Graf-Riesen & Maithreyan Kuppusamy & Andreas Unger & Kenichi Kimura & Martin Matijass & Henrique Baeta & Magdalena Podlacha & Daniel Haertter & Alexei P. Kudin & Martin Wiemann & Grzegorz Węgrzyn & Cornelia Kornblum & Jens Reimann & Wolfgang A. Linke & Pitter F. Huesgen & Wolfram S. Kunz & Bernd K. Fleischmann & Michael Hesse
- 1-21 Glycerol 3-phosphate acyltransferase exacerbates α-synuclein-induced toxicity by increasing lipid peroxidation
by Mengda Ren & Grace G. Y. Lim & Willcyn Tang & Kah-Leong Lim
- 1-21 5’tRNA-derived fragments modulate β-cell homeostasis and islet macrophage activation in type 2 diabetes
by Cristina Cosentino & Rémy Klein & Véronique Menoud & Claudiane Guay & Elena Aiello & Stefano Auddino & Gianfranco Di Giuseppe & Gea Ciccarelli & Alessandra Galli & Francesco Alabiso & Eleonora Mangano & Flora Brozzi & Karim Bouzakri & Stefania D’Adamo & Silvia Cetrullo & Giuseppe Quero & Andrea Mari & Sergio Alfieri & Andrea Giaccari & Teresa Mezza & Francesco Dotta & Guido Sebastiani & Romano Regazzi
- 1-21 Counting cells can accurately predict small-molecule bioactivity benchmarks
by Srijit Seal & William Dee & Adit Shah & Natacha Cerisier & Andrew Zhang & Esteban Miglietta & Katherine Titterton & Ángel Alexander Cabrera & Daniil Boiko & Alex Beatson & Gregory Slabaugh & Olivier Taboureau & Jordi Carreras Puigvert & Shantanu Singh & Ola Spjuth & Andreas Bender & Anne E. Carpenter
- 1-21 Functional requirement for Dicer helicase arginine methylation in 26 G siRNA biogenesis and oocyte meiotic program
by Nick Newkirk & Shin-Yu Chen & Tokiko Furuta & Kenneth A. Trimmer & Leilei Shi & Sabrina Stratton & Hongyuan Li & Xiaodong Cheng & Mark T. Bedford & Swathi Arur
- 1-21 A human-specific microRNA controls the timing of excitatory synaptogenesis
by Michael Soutschek & Alessandra Lo Bianco & Simon Galkin & Tatjana Wüst & Koen Wentinck & David Colameo & Tomas Germade & Fridolin Gross & Lukas von Ziegler & Johannes Bohacek & Betina Elfving & Pierre-Luc Germain & Jochen Winterer & Tatjana Kleele & Gerhard Schratt
- 1-21 Long-read sequencing of single cell-derived melanoma sublines reveals divergent and parallel genomic and epigenomic evolutionary trajectories
by Yuelin Liu & Anton Goretsky & Ayse G. Keskus & Salem Malikic & Tanveer Ahmad & E. Michael Gertz & Farid Rashidi Mehrabadi & Michael Kelly & Maria O. Hernandez & Charlie Seibert & Juan Manuel Caravaca & Kayla Kline & Yongmei Zhao & Ying Wu & Biraj Shrestha & Bao Tran & Arindam Ghosh & Xiwen Cui & Antonella Sassano & Laksh Malik & Breeana Baker & Cornelis Blauwendraat & Kimberley J. Billingsley & Sandra Burkett & Eva Perez-Guijarro & Glenn Merlino & Erin K. Molloy & S. Cenk Sahinalp & Chi-Ping Day & Mikhail Kolmogorov
- 1-21 Major urinary protein 1 modulates neuronal excitability in the medial prefrontal cortex in a male mouse model of affective empathy
by Kun Zhang & Dake Song & Yingying Zhang & Le Yang & Ban Feng & Ruixia Liu & Hengxin Gong & Longbiao Cui & Shanbo Ma & Yanwei Chen & Min Wang & Xinshang Wang & Yumei Wu & Ting Bai & Kun Xia & Minggao Zhao & Shuibing Liu
- 1-21 CAR-CD34 (+) hematopoietic stem/progenitor cells produced in vivo protect against thoracic aortic aneurysm and dissection
by Kaiwen Zhao & Yuzhen He & Renqi Yao & Shuangshuang Li & Lingxu Kong & Jinzhu Niu & Zan Zeng & Pengcheng Du & Hongqiao Zhu & Rong Zhao & Taiping Liang & Zaiping Jing & Jian Zhou
- 1-21 Endemism and regionalization patterns of squamate reptiles in Amazonia
by Marco Antônio Ribeiro-Júnior & Josué Anderson Rêgo Azevedo & Cristiano de Campos Nogueira & Silvana Amaral
- 1-21 Chemotherapy-induced senescence promotes stroma stiffness and antioxidant adaptation to promote chemoresistance in pancreatic ductal adenocarcinoma
by Xinxin Liu & Zhihua Huang & Bohan Yang & Yimeng Du & Yixin Sun & Enkui Zhang & Xiaofeng Kang & Chunyuan Xue & Kai Chen & Yongsu Ma & Xiaodong Tian & Xiaojie Xu & Yinmo Yang
- 1-21 Cancer cell-intrinsic inflammasome protein ASC links innate immunity with mitochondrial metabolism in driving pancreatic cancer
by Yu C. J. Chey & Bassam Kashgari & Louise McLeod & Georgette A. Radford & Linden J. Gearing & Ruby E. Dawson & Malvika Kharbanda & Joanne Lundy & Daniel Croagh & Charlotte Girard-Guyonvarc’h & Cem Gabay & Brooke A. Pereira & David Herrmann & Paul Timpson & John W. Finnie & Mohamed I. Saad & Dharmesh D. Bhuva & Bernardo S. Franklin & Florian I. Schmidt & Brendan J. Jenkins
- 1-21 Gut microbiome features associated with Bifidobacterium colonization predict personalized probiotic persistence patterns
by Sourav Goswami & Alisha Ansari & Chetan Sharaf & Paul W. O’Toole & Fergus Shanahan & Vineet Ahuja & Tarini Shankar Ghosh
- 1-21 Molecular mechanisms of transhydrogenase activity and allosteric regulation in eukaryotic type II PHGDH Ser33
by Sebastian Perrone & Javier O. Cifuente & Leonardo Mastrella & Alberto Marina & Beatriz Trastoy & Julia Becker-Kettern & Jean-François Conrotte & Adrià Alcaide-Jiménez & Francisco Corzana & Enrico Glaab & Marcelo E. Guerin & Carole L. Linster
- 1-21 Cyclophilin A stabilizes the capsid protein p72 to facilitate African swine fever virus replication
by Hui Kong & Liqin Yang & Zhenjiang Zhang & Ying Zhang & Linlin Liu & Wan Wang & Linfei Song & Yuanmao Zhu & Encheng Sun & Fang Li & Zhigao Bu & Xiangpeng Sheng & Dongming Zhao
- 1-21 HCMV infection disrupts barrier functions and promotes epithelial–mesenchymal transition in a cholangiocyte organoid model
by Zuodong Ye & Xinyan Hu & Syed Mushfiqur Rahaman & Yuelan Zheng & Xiaoman Zhang & Clara Sze Man Tang & Tsz Man Yau & Wang Ka Lee & Patrick Ho Yu Chung & Kenneth Kak Yuen Wong & Paul Kwong Hang Tam & Vincent Chi Hang Lui & Allen Ka Loon Cheung
- 1-21 DUSP26 protects against acute kidney injury by dephosphorylating p53 at serine 312
by Ying Fu & Yu Xiang & Yun Han & Juan Cai & Shaobin Duan & Anqun Chen & Zheng Dong
- 1-21 Spatial patterning of contractility by a self-organized mechanogen activity gradient underlies Drosophila gastrulation
by Gayatri Mundhe & Valentin Dunsing-Eichenauer & Jean-Marc Philippe & Élise Da Silva & Claudio Collinet & Thomas Lecuit
- 1-21 Systematic multi-omic deconvolution of the clinical heterogeneity of Down syndrome
by Micah G. Donovan & Srija Chillamcherla & Belinda A. Enriquez Estrada & Kayleigh R. Worek & Zenitha Sundararajan & Kyle W. Barstch & Kelly D. Sullivan & Matthew D. Galbraith & Angela L. Rachubinski & Joaquin M. Espinosa
- 1-21 Endothelial cannabinoid CB1 receptor deficiency reduces shear stress-induced arterial inflammation and lipid uptake
by Bingni Chen & Aishvaryaa Prabhu & Guo Li & Anna Kaltenbach & Yong Wang & George Shakir & Lucia Natarelli & Remco Megens & Yvonne Jansen & Srishti Ramanathan & Martina Geiger & Alexander Faussner & Michael Hristov & Daniel Richter & Xinyu Di & Mario van der Stelt & Vasiliki Triantafyllidou & Zhaolong Li & Nadja Sachs & Valentina Paloschi & Lars Maegdefessel & Susanna M. Hofmann & Martina Schifferer & Mikael Simons & Christian Weber & Donato Santovito & Stephan Herzig & Raquel Guillamat Prats & Sabine Steffens
- 1-21 A multi-fidelity tabular prior-data fitted network model for accurate prediction and uncertainty quantification
by Yan Shi & Cheng Liu & Aodi Yu & Zhenzhou Lu & Said Elias & Kai Cheng & Jiaqing Kou & Xin Chen & Yu Liu & Hong-Zhong Huang & Michael Beer
- 1-21 NASA’s ECOSTRESS satellite reveals widespread midday depression in ecosystem evapotranspiration
by Jingyi Bu & Jingfeng Xiao & Joshua B. Fisher & Yiqi Luo
- 1-21 β-cell FMO3-produced TMAO prevents NF-κB-mediated senescence and inflammation in ageing and diabetic conditions
by Baomin Wang & Yumei Yang & Yuen Man Ho & Huige Lin & Juntao Yuan & Kekao Long & Kenneth King Yip Cheng & Xiaomu Li
- 1-21 Remodeling synaptic connections via engineered neuron-astrocyte interactions
by Shin Heun Kim & Woojin Won & Gyu Hyun Kim & Yeon Hee Kook & Seungkyu Son & Songhee Choi & Dong Yeop Kang & Mingu Gordon Park & Young-Jin Choi & Seong Su Won & Juhee Shin & Yong Jeong & Kea Joo Lee & C. Justin Lee & Sangkyu Lee
- 1-21 The mosaic memory of large language models
by Igor Shilov & Matthieu Meeus & Yves-Alexandre de Montjoye
- 1-21 A ketogenic diet enhances aerobic exercise adaptation and promotes muscle mitochondrial remodeling in hyperglycemic male mice
by Pattarawan Pattamaprapanont & Roberto C. Nava & Rea Grover & Mia Formato & Eileen M. Cooney & Ana Paula Pinto & Ana B. Alves-Wagner & Anamica Das & Yuntian Guan & Meghana Annambhotla & Saanvi Acharya & Donato A. Rivas & Sarah J. Lessard
- 1-21 Low-intensity focused ultrasound-activated piezoelectric gel bandage for diabetic wound repair and neuropathic pain relief
by Xiao Li & Lizhou Lin & Mingrui Zhu & Xiaolong Li & Jifeng Yu & Dan Lu & Shaoyue Li & Yuting Shen & Bing Xiong & Chongke Zhao & Boyang Zhou & Haohao Yin & Huixiong Xu & Xin Guan
- 1-21 Mechanistic and antigenic boundaries of Henipavirus and Parahenipavirus glycoproteins
by Aaron J. May & Muralikrishna Lella & Jared Lindenberger & Alex Berkman & Ujjwal Kumar & Kejun Liu & Moumita Dutta & Maggie Barr & Rob Parks & Xiaozhi Lu & Madison Berry & Amanda Powell & Amelia G. Thompson & Sravya Sowdamini Nakka & Camila T. França & Xiao Huang & Arpita Mrigwani & Kijun Song & Victor Ilevbare & Salam Sammour & Chan Soo Park & Radha Devkota Adhikari & Priyanka Devkota & Katarzyna Janowska & Yanshun Liu & Garrett Scapellato & Taylor N. Spence & Katayoun Mansouri & Kevin Wiehe & Nancy J. Sullivan & Rosemarie Mason & Robert J. Edwards & Kevin O. Saunders & Barton F. Haynes & Priyamvada Acharya
- 1-21 TASP1-mediated cleavage of REV3L enhances the activity of DNA polymerase ζ in mammalian cells
by Jordane Goulas & Basile Guignier & Barbara Ben Yamin & Caroline Pouvelle & Andrey Yurchenko & Emmanuelle Despras & Luciana de Oliveira & Pierre Laplante & Dorian Bochaton & Damien Plassard & Wei Yang & François-Xavier Theillet & Xavier Veaute & Richard D. Wood & Sergey Nikolaev & Agnès M. Cordonnier & Patricia L. Kannouche
- 1-21 Spike-based alignment learning solves the weight transport problem
by Timo Gierlich & Andreas Baumbach & Akos F. Kungl & Kevin Max & Mihai A. Petrovici
- 1-21 Ultrasmall oral Saccharibacteria modulate gingival immunoactivation through type IV pili and TLR2-dependent endocytosis
by Deepak Chouhan & Alex S. Grossman & Kristopher A. Kerns & Kendall S. Stocke & Maya Kim & Pu-Ting Dong & Ajay Kumar & Lei Lei & Richard J. Lamont & Jeffrey S. McLean & Xuesong He & Batbileg Bor
- 1-21 A genus-wide interaction atlas across NS4B orthologues identifies a conserved role for UFMylation in orthoflavivirus replication
by Sreejith Rajasekharan & Viviana Andrea Barragan Torres & Yago Cortes Pinheiro Gomes & Lucas Wilken & Katharina Overhoff & Yen-Chia Lin & Shunmoogum A. Patten & Satoru Watanabe & Laurent Chatel-Chaix & Pietro Scaturro
- 1-21 Antioxidant lipid nanoparticles enhance mRNA stability for regeneration therapy and gene editing
by Benhao Li & Mengyao Zhao & Bowei Yang & Taihua Yang & Yongling Wang & Yaxin Hu & Miao Zhang & Jiahao Ge & Xianglong Tang & Ze Zhang & Hengqing Cui & Xiaoyuan Chen & Yi Yan Yang & Ling Peng & Qianqian Ni
- 1-21 Glucuronidation metabolomic fingerprinting to map host-microbe metabolism
by Nina R. Boyle & Josh J. Sekela & Mingxun Wang & Helena Mannochio-Russo & Jeong Joo Pyo & Min Soo Kim & Shuchang Tian & Imhoi Koo & Elliot S. Friedman & Ceylan Tanes & Mallappa Anitha & Yuan Tian & Ethan W. Morgan & Iain A. Murray & Joseph P. Zackular & Kyle Bittinger & James D. Lewis & Gary H. Perdew & Gary D. Wu & Babette S. Zemel & Pieter C. Dorrestein & Jordan E. Bisanz & Matthew R. Redinbo & Andrew D. Patterson
- 1-21 Three parsimonious spatiotemporal patterns in cerebellum reveal individual traits in function and behavior
by Shuo Lv & Jinlong Li & Ruoqi Yang & Xinyu Wu & Zhiming Wang & Wenjing Zhu & Tan Gao & Jia-Hong Gao & Guoyuan Yang
- 1-21 Deviation in development of dorsal association tracts during preadolescence links to concurrent and future cognitive performance and transdiagnostic psychopathology
by Danni Wang & Christopher J. Hammond & Betty Jo Salmeron & Xiang Xiao & Laura Murray & Hong Gu & Tianye Zhai & Annika Quam & Justine Hill & Hieu Nguyen & Hanbing Lu & Amy Janes & Thomas J. Ross & Yihong Yang
- 1-21 Programmable multiscale energy release in synergistic energetic composites with three dimensional printed architectures
by Yongjin Chen & Hui Ren & Haoyue Xin & Xinzhou Wu & Qingjie Jiao
- 1-21 A comparative transcriptomic analysis of mouse demyelination models and multiple sclerosis lesions
by Erin L. Aboelnour & Veronica R. Vanoverbeke & Elizabeth A. Maupin & Madelyn M. Hatfield & Katrina L. Adams
- 1-21 Early life exposure to N-nitrosamine drives genotoxicity, mutagenesis, and tumorigenesis in DNA repair-deficient mice
by Lindsay B. Volk & Monét Norales & Callie Karjane & Joshua J. Corrigan & Alper J. Alcaraz & Lee J. Pribyl & Nicolette A. Bugher & Megan Blawas & Isabella Dulski & Einthavy Arunachalam & Nina Gubina & Emily Michelsen & Kannammai Pichappan & Natalya Yakimchuk & Matilda Swanson & Duanduan Ma & Stuart S. Levine & Desiree L. Plata & Robert G. Croy & Leona D. Samson & John M. Essigmann & Carole L. Yauk & Sebastian E. Carrasco & Bevin P. Engelward
- 1-21 Disruption of the SAGA CORE triggers collateral degradation of KAT2A
by Paul Batty & Hannah Beneder & Caroline Schätz & Gabriel Onea & Maciej Zaczek & Ana P. Kutschat & Miriam Abele & Sophie Müller & Giulio Superti-Furga & Georg E. Winter & Davide Seruggia
- 1-21 Nuclear-specific reductive carboxylation of alpha-ketoglutarate fuels histone acetylation to induce chromatin accessibility and gene activation
by Abhisha Sawant Dessai & Nadya A. Elhalawany & Tao Dai & Justine J. Jacobi & Christian Prechtl & Alphonse N. Dimeck & Sierra R. Morton & Mark D. Long & Prashant K. Singh & Nagireddy Putluri & Mariana Lopes & Song Liu & Dominic J. Smiraglia & Katerina V. Gurova & Peder J. Lund & Leah A. Gates & Sung Yun Jung & Subhamoy Dasgupta
- 1-21 Regional heterogeneity in phenotypic and genetic associations between bone and brain in humans
by Lei Zhao & Yilan Tang & Wenhui Zhao & Shijiani Li & Jie Chen & Tian Ge & Yiheng Tu
- 1-21 Binary mineral nanoparticles enable intravascular delivery of metal ions to tumors for metalloimmunotherapy
by Bao Loc Nguyen & Ngoc Duy Le & Thi Oanh Oanh Nguyen & Daehyeon Ahn & Basavaraj Rudragouda Patil & Beomsu Kim & Cao Dai Phung & Duc-Vinh Pham & Jung Min Lee & Jiwoo Hong & Jae-Hoon Chang & Sae Kwang Ku & Jeonghwan Kim & Jong Oh Kim
- 1-21 Dyscoordination of thalamic reticular spindles is associated with social memory deficits in mice and humans with autism spectrum disorder
by Dongqi Cui & Xiaodan Wang & Ruosong Ai & Feng Gao & Huan Sun & Ying Zhang & Yixuan Lyu & Zhijie Zhang & Wen Li & Yuhang Qin & Yuxi Guo & Yinxia Liu & Ningxia Zhao & Juan Wang & Shen Li & Ying Wu & Siyuan Zhang & Changhe Wang & Feidi Wang & Yan Li
- 1-21 Microbial single-cell transcriptomics links gut microbiota functional states to metabolic changes in male mice
by Ziye Xu & Xin Long & Mengdi Song & Sanbao Zhang & Xiaoyue Li & Feifei Lv & Tianyu Zhang & Ting Cao & Yongcheng Wang
- 1-21 Patient-derived model capturing hypoxia and extracellular matrix remodelling of immunologically cold high-grade serous tumours
by Simona Plesselova & Hailey Axemaker & Kristin Calar & Oduduabasi Isaiah & Jared Wollman & Somshuvra Bhattacharya & Etienne Z. Gnimpieba & Darci M. Fink & Congzhou Wang & Hiruni Sumanasiri & Kristina W. Thiel & Maria Bell & Pilar de la Puente
- 1-21 Functional variants at 1p36.23 confer risk of schizophrenia through modulating RERE
by Yixing Liu & Junyang Wang & Hong Yang & Yifan Li & Changgai Mu & Xinglun Dang & Xinran Chen & Danyang Li & Mingna Li & Jiewei Liu & Shiwu Li & Jinfeng Yang & Xi Chen & Chen Zhang & Jin Feng & Xiong-Jian Luo
- 1-21 Therapeutic targeting of AREL1 in hepatic stellate cells attenuates MASH-related liver fibrosis
by Yang-Wen-Qing Zhang & Xiaoyu Pan & Minghe Zhang & Junyu Zhang & Hui Ren & Xinyu Zong & Xiaomian Li & Kequan Xu & Peng Xia & Tiangen Wu & Weijie Ma & Xi Chen & Chengming Qu & Wenzhi He & Yufeng Yuan
- 1-21 Chlorella-derived extracellular vesicle-based nanogels suppress cGAS-STING for treatment of radiation-induced lung injury
by Huiqun Hu & Feng Lu & Wenting Zhang & Zengwen Zhang & Jiarong Cui & Xiaoyue Lei & Jingyan Xia & Feng Xu
- 1-21 Robust intensification of projected regional precipitation extremes over Africa
by Akintomide A. Akinsanola & Thierry N. Taguela & Vishal Bobde
- 1-21 α/Sulfonyl-γ-AApeptide foldamers mitigate Alzheimer’s disease pathology by stabilizing transient helical domains in Aβ
by Heng Liu & Firoz Akhter & Asma Akhter & Xue Zhao & Xudong Wang & Haiqiang Yang & Jianyu Chen & Xinyu Xia & Laurent Calcul & Yi He & Chuanhai Cao & Libin Ye & Donghui Zhu & Jianfeng Cai
- 1-21 Multi-lineage hepatic organoids reveal toxic exosome mediated indirect hepatotoxicity
by Lei Sun & Yuying Zhang & Yudi Niu & He Yang & Lyu Zhou & Xiaodong Jia & Yihan Chen & Zhiqiang Liu & Tiantian Wang & Kaini Liang & Dongdong Fan & Sida Ling & Zhen Zeng & Yanan Du
- 1-21 Single cell spatial transcriptomics track the evolutionary hierarchy and microenvironment remodeling during breast carcinoma invasion
by Di Wang & Qichen Dai & Jingwen Guo & Dan Li & Changyuan Guo & Peiqing Ma & Feng Wen & Xiangyu Tong & Changhao Gong & Han Cheng & Meng Li & Ranjiaxi Wang & Jianlin Liu & Yingying Feng & Fengpu Fan & Xiaoqian Shi & Qian Zhang & Xingmei Shu & Yu Sun & Xunan Shen & Ziqing Deng & Jiaqi Liu & Fei Ma & Yipeng Wang & Lin Feng
- 1-21 ACSS2-KAT5 complex-driven histone crotonylation orchestrates a pro-inflammatory program to promote the transition from MASLD to MASH
by Xiao Wen & Keyan Wu & Mengyao Wang & Zihan Ma & Tao Wang & Jing Zhang & Bei Wang & Siyuan Chen & Jingyi Wang & Siyue Chen & Fan Yang & Chuwei Liu & Xianyang Chen & Lu Deng & Yafan Cheng & Qing Robert Miao & Baofa Sun & Xiongzhong Ruan & Kai Li & Yajun Duan & Wenquan Hu
- 1-21 Blockade of NKp46⁻ CCR6⁻ ILC3 autophagy protects against necrotizing enterocolitis by restoring energy metabolism balance in mice
by Junyu He & Meiqi Chen & Laiqin Peng & Qiqiong Wang & Yizhuang Lu & Yimin Chen & Xinyao Li & Yanling Mou & Jianjun Wang & Yuxiong Guo & Kai Wu & Yumei He
- 1-21 GRAF1-dependent endocytotic processes and the Golgi apparatus contribute to previously unrecognized intermediate stages of early ciliogenesis
by Kerstin N. Schmidt & Korbinian Buerger & Olga Maier & Anita Zügner & Larissa Osten & Patrick Hofstetter & Helga Othmen & Yulia Zaytseva & Anita Hecht & Clarissa Read & Reinhard Rachel & Ralph Witzgall
- 1-21 Self-assembling scaffolds epigenetically reactivate and electroactively guide neuronal regeneration to restore central neural circuits
by Shiqiang Tong & Shuai Ye & Fenfen Ma & Xiaoying Xie & Yinzhe Sun & Chuchu Ma & Tiantian Shi & Zheng Cheng & Chang Li & Weili Han & Laozhi Xie & Songlei Zhou & Jianing Gong & Chen Huang & Yukun Huang & Gan Jiang & Xiaolin Liu & Bing Li & Feng Zeng & Jingru Gong & Zhihua Wang & Xiaoling Gao & Qiyong Mei & Wei-Guang Li & Jun Chen
- 1-21 JAK inhibitors alleviate EGFR-inhibitor-induced diarrhea by protecting intestinal stem cells from adaptive-immune-exacerbated injury
by Yuan Cheng & Chenyue Xu & Dazhao Lv & Meng Tian & Haoyu Wang & Bingxue Yang & Leying Chen & Qing You & Shiyi Zhang
- 1-21 SBRT embedded in low-dose RT plus αPD-1 (immuno-EclipseRT, iERT) elicits CD8+ T cell immunity against bulky tumors via an IFN-I/NK/DC axis
by Ren Luo & Min Yu & Kai Kang & Yufeng Zhang & Shanghai Liu & Zhuoran Yao & Zichong Peng & Xuanwei Zhang & Shuangsi Liao & Zhou Su & Linglu Yi & Hui Wang & Wenhao Zhao & Yue Zheng & Guo Lin & Ruizhan Tong & Feifei Na & Youling Gong & Meijuan Huang & Bingwen Zou & Long Bai & Renming Zhong & Di Yan & Gabriele Niedermann & Jianxin Xue & You Lu
- 1-21 Two structurally mobile regions control the conformation and function of metamorphic meiotic HORMAD proteins
by Consuelo Barroso & Josh P. Prince & Punam Rattu & Mariana Sacerdoti & Daimona Koundé & Nuria Ferrandiz & Pablo Lopez-Jimenez & Syma Khalid & Enrique Martinez-Perez
- 1-21 Janus nanomotors for topical treatment of radiation-induced dermatitis
by Wen Zhang & Wei Liu & Xiaoyu Zhao & Yuanfang Chen & Changfen Bi & Shuqin Li & Bingwen Zou & Luntao Liu & Saijun Fan
- 1-21 CXCR4 induces memory formation over exhaustion in CAR-T cells to achieve durable leukemia targeting
by Ari Itoh-Nakadai & Minggao Liang & Michiho Shindo & Chen Bibi & Mariko Tomizawa-Murasawa & Saera Fujiki & Akiko Kaneko & Emi Kanamaru & Mari Hashimoto & Hiroshi Kajita & Yoshinari Ando & Miki Kojima & Jonathan Moody & Makoto Iwasaki & Shinsuke Takagi & Ryo Nakagawa & Saumya Agrawal & Hanae Amitani-Iijima & Kaori Sato & Yuriko Sorimachi & Nahoko Suzuki & Takehiro Fukami & Kazuharu Hanada & Satoshi Morita & Kazushige Katsura & Takehisa Matsumoto & Maiko Kobayashi & Masahiko Kato & Yasuyuki Negishi & Mikako Shirouzu & Yuho Najima & Keiyo Takubo & Chung Chau Hon & Naoyuki Uchida & Shuichi Taniguchi & Yukihide Momozawa & Piero Carninci & Leonard D. Shultz & Yoriko Saito & Michiel de Hoon & Jay W. Shin & Fumihiko Ishikawa
- 1-21 Macrophage ALDH2 drives immunotherapy resistance by silencing CXCL9 through metabolic-epigenetic crosstalk
by Huiying Fang & Jiazheng Sun & Qian Xiao & He Ren & Yuru Chen & Jiazhou Liu & Daqiang Song & Tiantian Chen & Linling Wu & Pin Wang & Jian Yue & Xiaoyu Wang & Qilin Yang & Yuxian Wei & Huimin Du & Weiyan Peng & Zhu Qiu & Li Zhang & Jingyuan Wan & Tong Liu & Guosheng Ren & Hongzhong Li
- 1-21 Chamber-specific chromatin architecture guides functional interpretation of disease-associated Cis-regulatory elements in human cardiomyocytes
by S. Haydar & R. Bednarz & P. Laurette & I. Sobitov & N. Díaz i Pedrosa & P. Videm & T. Lueneburg & S. Kuß & H. Lahm & M. Dreßen & M. Krane & C. Schmidt & B. A. Grüning & N. Voigt & K. Streckfuss-Bömeke & R. Gilsbach
- 1-21 Biomimetic model of corticostriatal micro-assemblies discovers a neural code
by Anand Pathak & Scott L. Brincat & Haris Organtzidis & Helmut H. Strey & Sageanne Senneff & Evan G. Antzoulatos & Lilianne R. Mujica-Parodi & Earl K. Miller & Richard Granger
- 1-21 Therapy induced senescence promotes immunogenicity in acute myeloid Leukemia through reduced EZH2 activity
by Diego Gilioli & Simona Fusco & Teresa Tavella & Tatiana Volpari & Antonella Santoro & Martin Schönlein & Kety Giannetti & Edoardo Carsana & Nicolò Gualandi & Roberta Noberini & Chiara Brombin & Salvatore Russo & Sara Feola & Yvonne Giannoula & Rui M. M. Branca & Janne Lehtiö & Tiina M. Sikanen & Markus Haapala & Laura Passerini & Angela Andrisani & Giacomo Farina & Alessia Zangari & Anastasia Conti & Lucrezia della Volpe & Matteo Barcella & Stefano Beretta & Federico Mario Aletti & Matteo Giovanni Carrabba & Silvia Gregori & Chiara Bonini & Ivan Merelli & Fabio Ciceri & Vincenzo Cerullo & Tiziana Bonaldi & Luca Vago & Clemens A. Schmitt & Raffaella Di Micco
- 1-21 Functional annotation of insulin-responsive genes in human adipocytes reveals PLCXD1 as a lipid storage regulator
by Scott Frendo-Cumbo & Danae Zareifi & Joëlle Bigay & Ana Rita Dias Araújo & Alina Lapp & Mattias Hansen & Teresa P. Reindl & Beatrice Engelmann & Felix Klingelhuber & Lina Cordeddu & Merve Elmastas & Jutta Jalkanen & Gianluca Renzi & Océane Buvry & Delphine Debayle & Hanin Allos & Marta López Yus & Sophie Weinbrenner & Katharina Schormair & Oveis Jamialahmadi & Alastair G. Kerr & Stefano Romeo & Ulrike Rolle-Kampczyk & Martin von Bergen & Lucas Massier & Natalie Krahmer & Romain Gautier & Bruno Antonny & Mikael Rydén & Niklas Mejhert
- 1-21 In vitro multi-organ invasion model for exploring cardiac resistance to cancer metastasis
by Amid Shakeri & Dhana Abdo & Matthew Ho Cheong Lei & Sargol Okhovatian & Garrett F. Beeghly & Anna Maria Popovic & Richard Jiang & Chuan Liu & Karl T. Wagner & Daniel Vosoughi & Jennifer Kieda & Jason E. Fish & Milica Radisic
- 1-21 Tmem110 regulates the conformation of TRPML1 to maintain endolysosomal homeostasis and prevent mitochondrial DNA leakage and pathological self-DNA processing
by Zunyong Feng & Yuanbo Pan & Jing Zhou & Liuxi Chu & Qiang Li & Xuanbo Zhang & Ping Wu & Zhiliang Xu & Yanjiao Huang & Jianhua Zou & Xiaokun Li & Xiaoyuan Chen & Zhouguang Wang
- 1-21 Triple targeting of STING, TGF-β, and PD-L1 boosts CXCL16–CXCR6 signaling for potent antitumor response
by Ming Yi & Tianye Li & Yinhui Gu & Mengke Niu & Dixuan Xue & Shengtao Hu & Yuze Wu & Bin Zhao & Di Zhang & Yingkang Ma & Minjun Zhang & Jing Zhang & Yongxiang Yan & Pengfei Zhou & Xiaojun Zhang & Zhuxian Zhou & Qian Chu & Kongming Wu & Zhijun Dai
- 1-21 Rational design of carbazole-based STING inhibitors for treating cGAS-STING pathway-driven inflammatory disorders
by Hui Li & Wei Zheng & Wenjing Bian & Mei Li & Zhidan Fan & Ziwen Feng & Xiaoyan Liu & Shiduo Zhang & Haohao Lu & Yinquan Huang & Jiaqing Jia & Yifan Zhang & Linlin Li & Chunchen Che & Haiguo Yu & Yibei Xiao & Qidong You & Xiaoli Xu
- 1-21 PD-1 blockade plus tyrosine kinase inhibitor remodels the tumor microenvironment in advanced renal cell carcinoma
by Liangyou Gu & Qi Zhang & Qiyang Liang & Cheng Peng & Yaohui Wang & Chenfeng Wang & Zhuoran Li & Yezhen Tan & Yanming Zhou & Qing Bi & Xiubin Li & Jin Luo & Qingbo Huang & Yan Huang & Xu Zhang & Xin Ma & Weimin Ci & Baojun Wang
- 1-21 C2orf74 orchestrates germ-Leydig crosstalk to inhibit white adipose tissue browning in male mice
by Li Zhao & Jialuo Han & Xinxin Wang & Qin Li & Qinghua Shi & Fangbiao Tao & Pilong Li & Chengxin Zhang & Qiang Liu & Juan Zhang
- 1-21 A generic reference defined by consensus peaks for single-cell ATAC-seq data analysis
by Qiuchen Meng & Xinze Wu & Wenchang Chen & Yubo Zhao & Chen Li & Zheng Wei & Xiaocheng Zeng & Jiaqi Li & Xi Xi & Sijie Chen & Catherine Zhang & Shengquan Chen & Jiaqi Li & Xiaowo Wang & Rui Jiang & Lei Wei & Xuegong Zhang
- 1-21 Native chromatome profiling reveals hundreds of metabolic enzymes in the nucleus across tissues
by S. Kourtis & A. Gañez Zapater & CR Elbæk & A. Schmidt & R. Ghose & A. Coll Manzano & L. Espinar Calvo & M. Guirola & N. Pardo-Lorente & M. Garcia-Cao & M. Pfeiffer & S. Haynes & F. Fontaine & A. Müller & S. Sdelci
- 1-21 A multimodal approach for visualizing and identifying electrophysiological cell types in vivo
by Eric Kenji Lee & Asım E. Gül & Greggory Heller & Anna Lakunina & Han Yu & Andrew Shelton & Shawn Olsen & Nicholas A. Steinmetz & Cole Hurwitz & Santiago Jaramillo & Pawel F. Przytycki & Chandramouli Chandrasekaran
- 1-21 DIS3 mutations enhance AID-driven translocations during B-cell activation, promoting transformation to multiple myeloma
by Tomasz M. Kuliński & Olga Gewartowska & Mélanie Mahé & Karolina Kasztelan & Nina Durys & Anna Stroynowska-Czerwińska & Marta Jedynak-Slyvka & Ewelina P. Owczarek & Debadeep Chaudhury & Marcin Nowotny & Aleksandra Pękowska & Bertrand Séraphin & Andrzej Dziembowski
- 1-21 Neutrophil-derived S100A8/A9 impairs megakaryocyte maturation in immune thrombocytopenia
by Jiaqian Qi & Meng Zhou & Jie Yin & Xiaofei Song & Yan Zhang & Haohao Han & Xueqian Li & Ziyan Zhang & Yaqiong Tang & Fei Yang & Depei Wu & Zhenyu Li & Yue Han
- 1-21 Characterization of membrane structures regulating primary ciliogenesis by quantitative isotropic ultrastructure imaging
by Quanlong Lu & Huijie Zhao & Ziam Khan & Adam Harned & Erina Kamiya & Valentin Magidson & Abhi Senthilkumar & Avaneesh Kilnagar & Phuong Thi Bich Doan & Sumeth Perera & Kedar Narayan & Christopher J. Westlake
- 1-21 Loss-of-function variants in the CAPN1 activator CD99L2 cause X-linked spastic ataxia
by Benita Menden & Rana D. Incebacak Eltemur & German Demidov & Marc Sturm & Joohyun Park & Chrisovalantou Huridou & Florian Fath & Astrid Nümann & Alexander Baumann & Illja J. Diets & Claudia Dufke & Martin Regensburger & Maria Rönnefarth & Vera Wilke & Nienke van Os & Stefan Vielhaber & Tim W. Rattay & Zacharias Kohl & Susana Peralta & Priscila Pereira Sena & Melanie Kellner & Nadine Weissert & Andreas Traschütz & Lena Zeltner & Kai Boelmans & Natalie Deininger & Leon Schütz & Caspar Gross & Ana Beatriz Hinojosa Amaya & Katrin Raupach & Holger Hengel & Florian Harmuth & Jakob Admard & Ingrid Bader & Sarah Baumann & Friedemann Bender & Andrea Bevot & Almut Bischoff & Felix Boschann & Rebecca Buchert & Daniel Buchzik & Nicolas Casadei & Claudia B. Catarino & Isabell Cordts & Kirsten Cremer & Marion Doebler-Neumann & Nadja Ehmke & Miriam Elbracht & Ruth J. Falb & Thomas Feindt & Zofia Fleszar & Lea Gerstner & Dieter Gläser & Ute Grasshoff & Sarah Grosch & Kathrin Grundmann & Alexander Gutschalk & Manja Haaga & Stefanie Hayer & Ute Hehr & Yorck Hellenbroich & Wolfram Henn & Barbara Herr & Rebecca Herzog & Veronka Horber & Jonas Deppe & Nadja Kaiser & Christiane Kehrer & Martin Kehrer & Jan Kern & Christoph Keßler & Katharina Khuller & Hannah Klinkhammer & Urania Kotzaeridou & Peter Krawitz & Martina Kreiss & Hanna Küpper & Alice Kuster & Lucia Laugwitz & Anne Lesemann & Nadine Lichey & Tobias Linden & Boris Macek & Janine Magg & Elisabeth Mangold & Eva Manka & Iris Marquardt & Karl Mehnert & David Mengel & Susanne Morlot & Barbara Oehl-Jaschkowitz & Martje G. Pauly & Melanie Philipp & Florentine Radelfahr & Maren Rautenberg & Angelika Riess & Carsten Saft & Beate Schlotter-Weigel & Axel Schmidt & Eva M. C. Schwaibold & Veronika Spahlinger & Stephanie Spranger & Katharina Marie Steiner & Claudia Stendel & Andreas Thieme & Andreas Tzschach & Ana Velic & Sarah Wiethoff & Carlo Wilke & Stephan Züchner & Simone Zittel & Ralf A. Husain & Marcus Deschauer & Felix Distelmaier & Andreas Dufke & Holm Graessner & Bernhard Hemmer & Heike Jacobi & Thomas Klockgether & Thomas Klopstock & Xenia Kobeleva & Georg-Christoph Korenke & Alma Kuechler & Gregor Kuhlenbäumer & Ingo Kurth & Huu Phuc Nguyen & Gilbert Wunderlich & Kirsten E. Zeuner & Stephan Klebe & Michaela Auer-Grumbach & Michaela Butryn & Jürgen Winkler & Dagmar Timmann & Matthis Synofzik & Bart van de Warrenburg & Rebecca Schüle & Ludger Schöls & Stephan Ossowski & Olaf Riess & Jonasz J. Weber & Tobias B. Haack
- 1-21 Dynamic transcriptomic remodeling in grafted human neural progenitor cells uncovers mechanisms for vision preservation in a rat model of retinitis pigmentosa
by Saba Shahin & Shaughn Bell & Bin Lu & Somanshu Banerjee & Vivek Swarup & Hui Xu & Jason Chetsawang & Stephany Ramirez & Jorge S. Alfaro & Alexander Laperle & Soshana Svendsen & Clive N. Svendsen & Shaomei Wang
- 1-21 Chaperone-mediated autophagy is required for regulatory T cell function
by Ranee Harrison & Floralba Gjergjova & Sandra Pelka & Adrian Macho-Gonzalez & Bhakti Chavda & Kristen Lindenau & Aiara Gazteluiturri Garcia & Rabia R. Khawaja & Jennifer T. Aguilan & Simone Sidoli & Susmita Kaushik & Yair Botbol & Ana Maria Cuervo & Fernando Macian
- 1-21 Endothelial FUNDC1 regulates metabolic reprogramming and the obesity-diabetes transition through the SIRT3/GATA2/endothelin-1 axis
by Jian Li & Dayong Li & Fujie Zhao & Yadong Wang & Hongmin Yao & Yin Wu & Junqing An & Zhixue Liu & Ye Ding & Ming-Hui Zou
- 1-21 RHOT1/2-driven mitochondrial membrane vesicles confer tumor-homing selectivity and enable in situ cancer vaccination
by Wanrong Meng & Bo Li & Chang Cao & Jialu He & Bingzhi Li & Yuhang Xie & Jiajing Gong & Wenxuan Wang & Rong He & Xuelei Ma & Guiquan Zhu & Longjiang Li
- 1-21 Pyruvate metabolism enzyme Dlat induces mitochondria protein hyperacetylation to limit fatty acid oxidation in the HFpEF heart
by Ying Wang & Dong Guo & Jin’ao Zhu & Xue Yang & Chan Wu & Jing Geng & Qi Liang & Nan Sun & Xiaona Niu & Yue Liu & Yanjie Guo & Pan Chang & Yan Li & Lang Hu
- 1-21 Microglial CD31 suppresses Aβ clearance and promotes Alzheimer pathology in 5×FAD mice
by Qiuzhi Zhou & Fei Sun & Yao Zhang & Xiaojian Cao & Mengzhu Li & Haitao Yu & Tao Jiang & Shihong Li & Weixia Wang & Jiazhao Xie & Ting He & Yanchao Liu & Dan Ke & Xiao-Chuan Wang & Peng Xu & Enjie Liu & Hong Chen & Jian-Zhi Wang
- 1-21 Systems acclimation to osmotic stress in zygnematophyte cells
by Jaccoline M. S. Zegers & Lukas Pfeifer & Tatyana Darienko & Kerstin Schmitt & Craig A. Dorsch & Cäcilia F. Kunz & Gerhard H. Braus & Birgit Classen & Oliver Valerius & Jan de Vries
- 1-21 Phytic acid (InsP6) activates HDAC3 epigenetic axis to maintain intestinal barrier function
by Sujan Chatterjee & Zachary Sin & Nguyen Tran & Loretta Vierra & Anuj Shukla & Tam Tran & George Koshkaryan & Kevin Ritter & Xue Bessie Su & Saharat Jolak Ragsac & Seungman Park & Qian Liu & Richard Van & Katherine Huang & Kayci Huff-Hardy & Richard Rood & Anas Gremida & Martin Gregory & Chien-Huan Chen & Mira V. Han & Parakkal Deepak & Adolfo Saiardi & Henning J. Jessen & Prasun Guha
- 1-21 FGF7 promotes load-bearing tendon regeneration and suppresses fibrosis
by Ruifu Lin & Junchao Luo & Hong Zhang & Chunmei Fan & Yue Hu & Ruojin Yan & Zetao Wang & Yang Fei & Chenqi Tang & Tianxi Huang & Tianshun Fang & Weiliang Shen & Sunbin Ling & Hongwei Ouyang & Xiao Chen & Zi Yin
- 1-21 Interplay between T3SS effectors, ExoY activation, and cGMP signaling in Pseudomonas aeruginosa infection
by Vincent Deruelle & Gabrielle Dupuis & Dorothée Raoux-Barbot & Elysa Lim & Roberto Ponce-López & Magda Teixeira Nunes & Daniel Ladant & Louis Renault & Undine Mechold
- 1-21 Restoring early postnatal synaptic dysregulation rescues motor neuron degeneration in a mouse model of Spinal and Bulbar Muscular Atrophy
by Tomoki Hirunagi & Kentaro Sahashi & Madoka Iida & Kazunari Onodera & Satoshi Yokoi & Yosuke Ogura & Genki Tohnai & Kenji Sakakibara & Kentaro Maeda & C. Frank Bennett & Yohei Okada & Masahisa Katsuno
- 1-21 Anti-PD-1 plus anti-CTLA-4 blockade overcomes immune exclusion in NSCLC brain metastases by enhancing CD8+ T cell responses and promoting tertiary lymphoid structure formation
by Kazutaka Hosoya & Hiroaki Ozasa & Takahiro Tsuji & Masahiro Oi & Yusuke Shima & Keiichiro Suminaga & Kentaro Hashimoto & Hiroshi Yoshida & Tomoko Funazo & Hitomi Ajimizu & Takashi Nomizo & Hironori Yoshida & Hiroyuki Katsuragawa & Kentaro Tsuji & Noritaka Sano & Shigeki Takada & Yohei Mineharu & Shigeto Nishikawa & Toshi Menju & Akihiko Yoshizawa & Yoshiki Arakawa & Hiroaki Wake & Toyohiro Hirai
- 1-21 Adipocyte small extracellular vesicle-derived microRNA-30a-3p exacerbates hepatic steatosis in high fat diet-fed male mice
by Tian Zhang & Longkun Hu & Diao Chen & Yongxin Chen & Fei Zhou & Ruohan Lou & Yuxia Zhou & Yuanyuan Wang & Mingjun Shi & Ke-Gang Linghu & Ligen Lin & Bing Guo
- 1-21 Polyadenylation of insulin mRNA by Tent5a regulates pancreatic beta cells
by Pamuditha N. Silva & Johanna E. Mayrhofer & Pavlo Potalitsyn & Geraldine O. Trüllinger & Svenja Godbersen & Nic Amstutz & Sebastian M. Siegner & Ben Kodiyan & Alexandra C. Title & Burcak Yesildag & Jacob E. Corn & Marc W. Schmid & Markus Stoffel
- 1-21 FKBP8 connects the Hsp70-Hsp90 chaperone machinery to the folding of membrane proteins
by Man-Xi Ge & Ming-Zhi Wu & Jia Ji & Zhao-Peng Li & Zhongjian Bai & Jieyan He & Josefa Chuh & Yixiao Zhang & Jing Li & Zai-Rong Zhang
- 1-21 Assembly of two functionally-distinct protein import complexes in the outer membrane of plant chloroplasts
by Sreedhar Nellaepalli & Domagoj Baretić & Astrid F. Brandner & Sybille Kubis-Waller & Duorong Xu & Ziad Soufi & Shuyang Cheng & Sireesha Kodru & Jun Fang & Úrsula Flores-Pérez & Vaishnavi Ravikumar & Pablo Pulido & Marjorie Fournier & Ivan Ahel & Syma Khalid & R. Paul Jarvis
- 1-21 Regionalized regulation of actomyosin organization influences cardiomyocyte cell shape changes during chamber curvature formation
by Dena M. Leerberg & Gabriel B. Avillion & Rashmi Priya & Didier Y. R. Stainier & Deborah Yelon
- 1-21 The BRCA1-A complex restricts replication fork reversal-dependent DNA repair in ATM deficient cells
by Arindam Datta & Jessica Jackson & Yaroslav I. Morozov & Jinghan Qiu & Alessandro Vindigni & Roger A. Greenberg
- 1-21 The SnRK1–RAP2.4h–PIP2 module contributes to the trade-off between growth and hypoxia tolerance in plants
by Ke Liao & Lin-Na Wang & Xin-Yu Lu & Hui-Min Zhang & Zhong-Rong Yan & Tian-Yi Zhang & Yi Li & Ling-Jing Xu & Qiao-Ling Zhong & Qin-Fang Chen & Ying Zhou & Ruo-Han Xie & Shi Xiao
- 1-21 BRD4 directs myofiber identity and metabolic adaptation through CHD4 cooperation
by Zheng Zhou & Lin Liu & Zhisheng Xu & Danxia Zhou & Anqi Liu & Jiachen Yuan & Gonghao Shen & Qiqi Guo & Yujing Yin & Yan Mao & Wanping Sun & Liwei Xiao & Cheng Lv & Abdukahar Kiram & Likun Yang & Yuhuan Jia & Lu Ke & Lei Fang & Weiqin Li & Tingting Fu & Zhenji Gan
- 1-21 DDX6 undergoes phase separation to modulate metabolic plasticity and chemoresistance
by Hongjie Bi & Wei Li & Lili Ren & Honghai Zhang & Lei Dong & Anthony Chan & Xueer Wang & Lu Yang & Xiaoxu Zhang & Meilin Xue & Hanjun Qin & Xiwei Wu & Johanna Ten Hoeve-Scott & Bin Zhang & Ling Li & Mark Wunderlich & James C. Mulloy & Steven T. Rosen & Jianjun Chen & Xiaobo Li & Chun-Wei Chen & Rui Su
- 1-21 Regulation of physical activity and energy expenditure through Phf6 in the medial preoptic area
by Jingjie Wang & Bing Liu & Xiaohua Wu & Jingjing Sun & Yaxin Wang & Liang He & Linhua Gan & Xiangfeng Du & Jingyu Ruan & Lingzhi Pi & Qing-Feng Wu & Ju Huang
- 1-21 Recurrent intra-tumour heterogeneity is a hallmark of metastatic prostate cancer
by Sirui Weng & Lachlan Cain & James Comben & Yangyi Zhang & Timothy Semple & Sara Alaei & David Yoannidis & Luciano Martelotto & Catherine Mitchell & Anupama Pasam & Richard J. Young & Benjamin Blyth & Joy Hendley & Yuzhou Feng & Heather Thorne & Roslyn Wallace & Joanna Chan & Julia Como & Lisa Devereux & Himisha Beltran & Daniel Wetterskog & Scott Williams & Anthony T. Papenfuss & Belinda Parker & Paul Neeson & Gerhardt Attard & David Quigley & David L. Goode & Richard B. Pearson & Luc Furic & Anna S. Trigos & Shahneen Sandhu
- 1-21 Haemodynamic control of zonated liver function via instructive vascular Wnt signalling
by Ki Hong Lee & Moritz Jakab & Alexey Uvarovskii & Dimitris Papageorgiou & Donato Inverso & Jingjing Shi & Maria Riedel & Stephanie Gehrs & Shubhada Kulkarni & Stefanie Bobe & Adnan Ali & Suchira Gallage & Sophia Siegmund & Johannes Gahn & Leon Blankenhorn & Michael Buettner & Gernot Poschet & Karsten Richter & Oksana Voloshanenko & Roxana Ola & Thomas Korff & Friedemann Kiefer & Mathias Heikenwalder & Michael Boutros & Christof Niehrs & Carolin Mogler & Jeroen Krijgsveld & Simon Anders & Hellmut G. Augustin
- 1-21 Local, but not circulating, complement C3 shapes immune checkpoint blockade efficacy by controlling myeloid cell infiltration
by Yuki Miyai & Yukihiro Shiraki & Ryota Ando & Daisuke Sugiyama & Yoshitaka Sato & Katsuhiro Kato & Naoya Asai & Fuyang Cao & Nobuyoshi Nagao & Kana Tanabe & Masahiro Nakatochi & Tetsunari Hase & Toyofumi Fengshi Chen-Yoshikawa & Tomoko Kobayashi & Shintaro Iwama & Nobutoshi Esaki & Shinji Mii & Hiroshi Arima & Hiroshi Kimura & Masahide Takahashi & Yuichi Ando & Atsushi Enomoto
- 1-21 Mapping functional non-coding variation in individual human genomes through haplotyping, multiomics, and deep learning
by Mikhail D. Magnitov & Robin H. van der Weide & Aster F. Witvliet & Miguel Hernández-Quiles & Moreno Martinović & Hans Teunissen & Luca Braccioli & Michiel Vermeulen & Elzo de Wit
- 1-21 Reversible control of post-Golgi transport by brefeldin A reveals recycling endosome maturation during glycosylphosphatidylinositol-anchored protein transport
by Arata Takiguchi & Ho Tung Shek & Shogo Sasaki & Tatsuya Tago & Taisei Uehara & Yumi Goto & Kiminori Toyooka & Kazuo Kurokawa & Takuro Tojima & Akihiko Nakano & Makoto Maeda & Takunori Satoh & Akiko K. Satoh
- 1-21 Hippocampo-neocortical interaction as compressive retrieval-augmented generation
by Eleanor Spens & Neil Burgess
- 1-21 Cerebellar activity is triggered by reach endpoint during learning of a complex locomotor task
by Andry Andrianarivelo & Heike Stein & Jeremy Gabillet & Clarisse Batifol & Abdelali Jalil & N. Alex Cayco Gajic & Michael Graupner
- 1-21 SLC1A5 prevents aortic aneurysm and dissection by glutaminolytic-epigenetic orchestration of vascular smooth muscle cell homeostasis
by Pinglian Yang & Zhechang Gao & Weile Ye & Chunhong Zhou & Zhihua Zheng & Meiming Su & Yu He & Zhuoming Li & Jaroslav Pelisek & Ke He & Suowen Xu & Jiaojiao Wang & Zhiping Liu
- 1-21 Fluorofenidone ameliorates pressure overload-induced heart failure by stabilizing SERCA2a in male mice
by Quan Liu & Huayang Li & Jiantao Chen & Qiushi Ren & Tongxin Chu & Li Luo & Zeyu Li & Suiqing Huang & Liqun Shang & Adilai Maihemuti & Zhuoming Zhou & Zhilin Miao & Kaizheng Liu & Jinyu Pan & Kangni Feng & Mengya Liang & Zhongkai Wu
- 1-21 PCSK5 promotes angiogenesis and cardiac repair after myocardial infarction
by Jieyu Guo & Siyu Ma & Jinghua Ma & Ming Liu & Fei Ge & Xinhong Wang & Jiayi Lin & Nan Jiang & Xiaoke Lin & Zhipeng Lian & Zheng Zuo & Liliang Li & Genmao Cao & Yongbo Li & Xiangxiang Wei & Xianlong NG & Xiuling Zhi & Elena Osto & Yuxiang Dai & Jun Li & Lixin Wang & Hong Jiang & Dan Meng
- 1-21 Intrinsic mechanisms and microenvironmental cues fine-tune plasticity of esophageal progenitors
by Louison Descampe & Benjamin Dassy & Fadi Charara & Ligia Craciun & Laurine Verset & Sheleya Pirard & Quentin Verheye & Morgane Leprovost & Marie Isabelle Garcia & Alizée Vercauteren Drubbel & Benjamin Beck
- 1-21 Two distinct SWI/SNF complexes direct chromatin-linked transcriptional programs in Toxoplasma
by Dominic Schwarz & Benicio Tapia & Sebastian Lourido
- 1-21 Spinal nociceptive denervation impedes subsequent chronic autonomic remodeling after myocardial infarction in male swine
by Valerie Y. H. van Weperen & Jonathan D. Hoang & Neil R. Jani & Shail Avasthi & Christopher A. Chan & Kuan Cao & Zulfiqar A. Lokhandwala & Maryam Emamimeybodi & Karim Atmani & Marmar Vaseghi
- 1-21 Heterogeneous endocrine cell composition defines human islet functional phenotypes
by Carmella Evans-Molina & Yasminye D. Pettway & Diane C. Saunders & Seth A. Sharp & Thomas SR. Bate & Han Sun & Heather Durai & Shaojun Mei & Anastasia Coldren & Corey Davis & Conrad V. Reihsmann & Alexander L. Hopkirk & Jay Taylor & Amber Bradley & Radhika Aramandla & Greg Poffenberger & Adel Eskaros & Regina Jenkins & Danni Shi & Ke Xu & Hakmook Kang & Varsha Rajesh & Swaraj Thaman & Fan Feng & Jean-Philippe Cartailler & Alvin C. Powers & Kristin Abraham & Anna L. Gloyn & Joyce C. Niland & Marcela Brissova
- 1-21 Microbiota-derived IPA protects against colitis by regulating intestinal HMGCS2-mediated ketogenesis to facilitate mucosal healing
by Yanan Zhang & Shuyu Tu & Xian Shao & Jinxin Meng & Zhuobiao Zhang & Wei Wei & Xuping Jing & Zhewen Qin & Jianan Wu & Weilv Xu & Bofei Dong & Jinsong Gao & Aijuan Qu & Shuxian Chen & Li Zhang & Peng Gong & Bo Shan & Hui Shi & Shu Jeffrey Zhu
- 1-21 Activation of hypothalamic-pontine-spinal pathway promotes locomotor initiation and functional recovery after spinal cord injury in mice
by Chengyue Ji & Yunfan Zhang & Zeyu Lin & Ziqi Zhao & Zhuolei Jiao & Zhiyuan Zheng & Xiaoxue Shi & Xiaofei Wang & Ziyu Li & Shuisheng Yu & Yun Qu & Yaxuan Wei & Tan Rui & Bowen Zheng & Taorong Xie & Hanyu Shi & Qifang Wang & Xiao Yu & Xiaohong Xu & Juxiang Chen & Jin Fan & Weihua Cai & Yi Li
- 1-21 Dysregulation of macrophage lipid metabolism underlies intracellular bacterial neuroinvasion
by Zhou Sha & Kun Yang & Shoupeng Fu & Xiaoyong Tong & Hui Yang & Huiling Fang & Qianqian He & Ning Li & Xinyu Shu & Qi Liu & Beibei Fu & Jin Liu & Qian Li & Hao Zeng & Xiaokai Zhang & Rui Yao & Xushuo Zhang & Wenjin Guo & Xuhu Mao & Mian Long & Xiaoyuan Lin & Quanming Zou & Haibo Wu
- 1-21 Targeting a super-enhancer induced aldehyde dehydrogenase metabolic loop mitigates CDK4/6 inhibitor resistance in estrogen receptor-positive cancers
by Xiaochuan Chen & Shini Liu & Dandong Luo & Dezheng Lin & Jun Liu & Huanmiao Zhan & Shuqin Chen & Peng Deng & Zhaoliang Yu
- 1-21 A week in the life of the human brain reveals stable states punctuated by chaotic-like transitions
by Maxwell B. Wang & Max G’Sell & James F. Castellano & R. Mark Richardson & Avniel Singh Ghuman
- 1-21 Loss of the USP22 deubiquitylase confers resistance to chemotherapy in small cell lung cancer
by Scott Best & Daniel S. Hippe & Eli Grunblatt & Jackson Fatherree & Pritha Chanana & Feinan Wu & Richard Ivey & Jacob J. Kennedy & David Sokolov & Ali Ibrahim & Haodong Xu & Raymond J. Monnat Jr & Lucas B. Sullivan & Patrick Paddison & Amanda G. Paulovich & David MacPherson
- 1-21 Evolutionary diversity of cell-type-specific expression and stress response in Brassicaceae roots
by Guannan Wang & Kook Hui Ryu & Andrea Dinneny & Jiyoung Lee & Dong-Ha Oh & Prashanth Ramachandran & Marina Oliva & Ryan Lister & José R. Dinneny & John Schiefelbein & Maheshi Dassanayake
- 1-21 DPEP2 suppresses hyperinflammation via metabolic reprogramming of macrophages in sepsis
by Wenchen Luo & Wei Xu & Qimeng Yin & Jieqiong Song & Jie Wang & Yian Guan & Jian Huang & Jian Yu & Kefeng Zou & Danfeng Jin & Chao Xu & Min Qiu & Zhixin Qiu & Jing Zhong
- 1-21 A SET domain-containing protein and HCF-1 maintain transgenerational epigenetic memory
by Chenming Zeng & Giulia Furlan & Miguel Vasconcelos Almeida & Juan C. Rueda-Silva & Jonathan Price & Helena Santos-Rosa & Jingxiu Xu & Yan Kuang & Enric Cata Socias & Jonas Mars & Pedro Rebelo-Guiomar & Meng Huang & Shouhong Guang & Falk Butter & Eric A. Miska
- 1-21 Unveiling the emission mechanism in analog-doped carbazole-based organic afterglow materials
by Zesen Lin & Peng Lan & Zheng Yin & Xiaochun Fan & Jie Kong & Xianhe Zhang & Wei Zhang & Rengo Yoshioka & Xun Tang & Zhu Wu & Youichi Tsuchiya & Ryota Kabe & Meng Zhou & Chihaya Adachi & Bin Liu
- 1-21 Mapping histologic and functional maturation of human endocrine pancreas across early postnatal periods
by Diane C. Saunders & Fan Feng & Alexander L. Hopkirk & Kristie I. Aamodt & Nathaniel Hart & Fong Cheng Pan & Conrad V. Reihsmann & Nike Izmaylov & Shaojun Mei & Brandon A. Sherrod & Corey Davis & Nongyao Nonpanya & Yasminye D. Pettway & Keval P. Patel & Kai S. Lee & Jeff Duryea & Rachana Haliyur & Radhika Aramandla & Heather Durai & Greg Poffenberger & Alexandra Martin & Amanda L. Posgai & Irina Kusmartseva & Maria L. Beery & Mingder Yang & Ke Xu & Hakmook Kang & Dale L. Greiner & Leonard D. Shultz & Jean-Philippe Cartailler & Rita Bottino & Mark A. Atkinson & Christopher V. E. Wright & Alvin C. Powers & Marcela Brissova
- 1-21 Persistent representation of a prior schema in the orbitofrontal cortex facilitates learning of a conflicting schema
by Ido Maor & James Atwell & Ilana Ascher & Yuan Zhao & Yuji K. Takahashi & Evan Hart & Francisco Pereira & Geoffrey Schoenbaum
- 1-21 TMEM120A maintains adipose tissue lipid homeostasis through ER CoA channeling
by Yoon Keun Cho & Junhyuck Lee & Yujin L. Jeong & Minki Shim & Xuan Linh Mai & Chang Seomoon & Cheol Woon Jung & Yoon Ha Choi & Sik Namgoong & Young-Suk Jung & Sung Won Kwon & Juyong Lee & Je Kyung Seong & Sunghyouk Park & Emilio P. Mottillo & James G. Granneman & Dong-Kyu Lee & Jong Kyoung Kim & Yun-Hee Lee
- 1-21 A circuit linking dentate gyrus and retrosplenial granular cortex regulates fracture healing in male mice
by Wei Zhang & Wei Zhang & Yue Guo & Danni Chen & Xiaowen Jiang & Jingjing Zhang & Erman Chen & Yinfeng Yuan & Wanyi Wu & Yiming Qian & Xiaohua Yu & Yongjie Wang & Weixu Li
- 1-21 Complementary roles of cell-type-specific plasticity in shaping neocortical dynamics for learning action timing
by Shouvik Majumder & Koichi Hirokawa & Zidan Yang & Anant Jain & Ronald Paletzki & Charles R. Gerfen & Lorenzo Fontolan & Sandro Romani & Ryohei Yasuda & Hidehiko K. Inagaki
- 1-21 Time-dependent deployment of medial prefrontal cortical representations in male mice
by Junior Samuel Lopez-Yepez & Anna Barta & Juliane Martin & Maria Moltesen & Tsz-Fung Woo & Oliver Hulme & Ebru Demir & Duda Kvitsiani
- 1-21 Multi-modal AI for opportunistic screening, staging and progression risk stratification of steatotic liver disease
by Yuan Gao & Chunli Li & Wanxing Chang & Bai Du & Xianghua Ye & Yee Hui Yeo & Yingda Xia & Heng Guo & Xiaoming Zhang & Wei Liu & Ruobing Bai & Beibei Li & Yang Hong & Jiawen Yao & Le Lu & Kai Cao & Ke Yan & Jun Chen & Jie Li & Yang Hou & Ling Zhang & Yu Shi
- 1-21 Adaptation to cystine limitation stress confers a targetable lipid metabolism vulnerability in pancreatic ductal adenocarcinoma
by Yunzhan Li & Zekun Li & Qin Li & Dongxiao Sun & Bo Ni & Mingjun Tan & Ashley E. Shay & Min Wang & Chenyang Meng & Guangcong Shen & Boyang Fu & Yueying Shan & Shiqi Zhang & Rifah Rownak Tanshee & Tianxing Zhou & Yongjie Xie & Kun-Ming Chen & Bin Qiao & Yunkun Dang & Scot R. Kimball & Guanshi Zhang & Girish H. Rajacharya & Pankaj K. Singh & Xiuchao Wang & Jihui Hao & Shengyu Yang
- 1-21 Polar chromosomes are rescued from missegregation by spindle elongation-driven microtubule pivoting
by Isabella Koprivec & Valentina Štimac & Mario Đura & Kruno Vukušić & Petra Mikec & Iva M. Tolić
- 1-21 Self-adaptive nanozymes with enhanced multi-enzyme activities for sequential multimodal therapy of drug-resistant bacteria-infected wounds
by Xiaoyong Zhang & Hang Yu & Kai Zhu & Yao Xiao & Yuxuan Gong & Dandan Che & Wanyi Chen & Guoxing You & Xiyun Yan & Quan Wang & Kelong Fan & Hong Zhou & Gan Chen
- 1-21 FGFR signaling establishes spatial gradients of secretory cell identities along the airway proximal-distal axis
by Alexandros Sountoulidis & Jonas Theelke & Andreas Liontos & Alexandra B. Firsova & Orane Eliot & Janine Koepke & Pamela Millar-Büchner & Louise Mannerås-Holm & Åsa Björklund & Athanasios Fysikopoulos & Antonia Kelm & Eleni Bouloukou & Konstantin Gaengel & Fredrik Bäckhed & Christer Betsholtz & Werner Seeger & Saverio Bellusci & Christos Samakovlis
- 1-21 Cross-species comparison of amniote single-cell transcriptomes reveals evolutionary conservation and divergence in the chicken immune system
by Fei Wang & Jilong Ren & Yaqi Zhou & Wuqiang Huo & Huichao Liu & Mumu Qin & Yi Jing & Zhongtao Yin & Tao Shi & Huiquan Shan & Guanghui Tan & Haoping Wang & Xi Guo & Junpu Mei & Zhen Yue & Zhuocheng Hou & Huaijun Zhou & Jiuzhou Song & Søren Egedal Degn & Lin Lin & Yonglun Luo & Feilong Meng & Xiaodong Fang & Haihan Zhang & Xi He & Lingzhao Fang & Yu Jiang
- 1-21 Prodrug nanoplatform for triggering ferroptosis to eliminate senescent cells in age-associated pathologies
by Chengkang Jin & Xiaoling Xu & Ning Yao & Hairui Zhang & Changjiang Chen & Lingyao Zeng & Zhiyun Liu & Lanjie Lei & Shumao Cui & Chengping Wen & Liyun Shi
- 1-21 Oncogenic Ras drives EED degradation and PRC2 dysfunction to promote aggressive squamous cell carcinoma
by Meng-Yen Li & Aubrey Houser & Pradeep Cheema & Xiang Yu Zheng & Paula Restrepo & Pooja Flora & Yudong Zhou & Gil Segal-Dalal & Eldad Silberstein & Xiaotao Zhang & Markus Schober & Deyou Zheng & Idan Cohen & Andrew L. Ji & Elena Ezhkova
- 1-21 Towards robust foundation models for digital pathology
by Jonah Kömen & Edwin D. de Jong & Julius Hense & Hannah Marienwald & Jonas Dippel & Philip Naumann & Eric Marcus & Lukas Ruff & Maximilian Alber & Jonas Teuwen & Frederick Klauschen & Klaus-Robert Müller
- 1-21 Rapid endothelialization of printed vascular grafts by perivascular niche-circulating endothelial progenitors crosstalk
by Zhe-qian Zhang & Ping-Ping Yuan & Cong Yao & Yu-xin Lu & Yi-dong Hu & Zhen-nan Qiu & Wen-yu Zhan & Xin-chi Zhang & Yu-jiao Wang & Xiao-peng Wu & Ya-jing Zhao & Peng-yu Wang & Ning Leng & Cun Zhang & Jian-kang He & Wei Wu
- 1-21 Mechanical rejuvenation of senescent stem cells and aged bone via chromatin remodeling
by Xiaojing Liu & Yuanxin Ye & Zhonghan Li & Li Liao & Qiang Wei
- 1-21 Acute rapamycin treatment reveals distinct mechanisms of dysfunction in a maternal inflammation mouse model
by JE Le Belle & M. C. Condro & C. Cepeda & KD Oikonomou & K. Tessema & L. Dudley & J. Schoenfield & R. Kawaguchi & D. Geschwind & AJ Silva & Z. Zhang & K. Shokat & NG Harris & HI Kornblum
- 1-21 Leveraging genomic and transcriptomic data of diverse ancestry to uncover mechanisms of psychiatric risk in the adult and developing brain
by Aarti Jajoo & Vijetha Balakundi & Chris Chatzinakos & Athina Aruldass & Cindy Wen & Ilse G. C. Kolmans & Artemis Iatrou & Joel E. Kleinman & Kerry J. Ressler & Tim Bigdeli & Michael J. Gandal & Nikolaos P. Daskalakis
- 1-21 A small nucleolar RNA dictates the structure and function of translating ribosomes in Leishmania
by K. Shanmugha Rajan & Saurav Aryal & Sharanya Murugeshan & Yinzhou Zhu & Anat Bashan & Mika Olami & Hava Madmoni & Yuko Nobe & Tirza Doniger & Smadar Cohen-Chalamish & Eric Prina & Pascale Pescher & Tom Beneke & Masato Taoka & Christopher L. Holley & Ron Unger & Gerald F. Späth & Ada Yonath & Shulamit Michaeli
- 1-21 Spatiotemporal dynamics of the human cortical functional hierarchy across the lifespan
by Qiongling Li & Xinyuan Liang & Debin Zeng & Tengda Zhao & Xuhong Liao & Gaolang Gong & Qian Wang & Chenxuan Pang & Qian Yu & Xiaoxi Dong & Yirong He & Yanchao Bi & Pindong Chen & Rui Chen & Yuan Chen & Taolin Chen & Jingliang Cheng & Yuqi Cheng & Zaixu Cui & Zhengjia Dai & Yao Deng & Yuyin Ding & Qi Dong & Dingna Duan & Jia-Hong Gao & Qiyong Gong & Ying Han & Zaizhu Han & Chu-Chung Huang & Ruiwang Huang & Ran Huo & Lingjiang Li & Ching-Po Lin & Qixiang Lin & Bangshan Liu & Chao Liu & Ningyu Liu & Ying Liu & Yong Liu & Jing Lu & Leilei Ma & Weiwei Men & Shaozheng Qin & Wen Qin & Jiang Qiu & Shijun Qiu & Tianmei Si & Shuping Tan & Yanqing Tang & Sha Tao & Dawei Wang & Fei Wang & Jiali Wang & Pan Wang & Xiaoqin Wang & Yanpei Wang & Dongtao Wei & Yankun Wu & Peng Xie & Xiufeng Xu & Yuehua Xu & Zhilei Xu & Liyuan Yang & Chunshui Yu & Huishu Yuan & Zilong Zeng & Haibo Zhang & Xi Zhang & Gai Zhao & Yanting Zheng & Suyu Zhong & Mingrui Xia & Shuyu Li & Yong He
- 1-21 Distinct and compensatory roles of STAG1 and STAG2 in post-mitotic genome refolding
by Manzhu Wang & Yabing Zhang & Fengnian Shan & Chongren Pei & Fuhai Liu & Sijian Xia & Lirong Shu & Bicheng Li & Dannan Jing & Yongjia Weng & Han Zhao & Yinzhi Lin & Yali Yu & Baiyue Wang & Haoyue Zhang
- 1-21 PregMedNet: Multifaceted maternal medication impacts on neonatal complications
by Yeasul Kim & Ivana Marić & Chloe M. Kashiwagi & Lichy Han & Philip Chung & Jonathan D. Reiss & Lindsay D. Butcher & Kaitlin J. Caoili & Eloïse Berson & Lei Xue & Camilo Espinosa & Tomin James & Sayane Shome & Feng Xie & Marc Ghanem & David Seong & Alan L. Chang & S. Momsen Reincke & Samson Mataraso & Chi-Hung Shu & Davide De Francesco & Martin Becker & Wasan M. Kumar & Ronald J. Wong & Brice Gaudilliere & Martin S. Angst & Gary M. Shaw & Brian T. Bateman & David K. Stevenson & Lawrence S. Prince & Nima Aghaeepour
- 1-21 MELK inhibition disrupts actin cytoskeleton and broadly restricts human coronavirus infections
by Kuai Yu & Qiaorui Yao & Dong Wang & Qingtao Hu & Dandan Li & Fang Li & Fenghua Chen & Jingyi Su & Ting Huang & Qing Zhang & Zishuo Lin & Wei Ran & Yiliang Wang & Yuzheng Zhou & Shuai Wen & Yuting Lin & Yaming Jiu & Jingxian Zhao & Jincun Zhao
- 1-21 Peptide-functionalized membrane camouflage for endogenous H2S-induced photothermal immunotherapy of orthotopic colorectal cancer
by Kai Cheng & Fang Zhang & Jia-Hua Zou & Xiao-Ling Lei & Xiao-Ting Xie & Yan-Bin Guo & Guo-Ping Wang & Bo Liu & Yuan-Di Zhao & Jiang Xia & Jin-Xuan Fan
- 1-21 Targeting phenol-soluble modulin α3-driven M1 macrophage polarization and necroptosis mitigates MRSA infection in mice
by Bo Ma & Zhi Li & Hua Xu & Yuting Chen & Yingchao Fang & Jianwei Xie
- 1-21 Loss of Echs1 in neural stem and progenitor cells impairs neurogenesis via ER stress activation and lipid metabolic reprogramming
by Chun-Hui Duan & Pei-Pei Liu & Xin Sun & Wen-Hui Ma & Jia-Ying Pang & Zi-Han Zhang & Xiao Li & Lin-Fei Jiao & Hong-Zhen Du & Zhao-Qian Teng & Hou-Zao Chen & Chang-Mei Liu
- 1-21 Targeting macrophage ferritin heavy chain mitigates ferroptosis and lung injury in experimental acute respiratory distress syndrome
by William Z. Zhang & Kihwan Kim & Divya Bhatia & Lynne Faherty & Will Simmons & Eleni Kallinos & Sebastian E. Carrasco & Katherine L. Hoffman & Sean Houghton & Chia-Lang Hsu & Leora Haber & Cem Meydan & Christopher E. Mason & Ananda S. Mirchandani & Sarah R. Walmsley & Parag Goyal & Kuei-Pin Chung & Karla V. Ballman & David Redmond & Joseph D. Mancias & Augustine M. K. Choi & Edward J. Schenck & Maria Plataki & Suzanne M. Cloonan
- 1-21 Double-stranded RNA and ROS scavenging nanoplatform for modulating skin inflammation
by Lian Cui & Hengli Lu & Jiangluyi Cai & Ying Li & Zeyu Chen & Yiwei Zhang & Bingjie Li & Yuanyuan Wang & Nan Yang & Lingling Yao & Rui Ma & Xin Wang & Yingyuan Yu & Dawei Huang & Peiyao Zhu & Hao Mei & Qianyu Chen & Yu Zhuang & Yunlu Gao & Ning Yu & Lingjuan Zhang & Chunyuan Guo & Huijing Xiang & Yuling Shi
- 1-21 Phosphorylation of SF3B1 by CDK11 orchestrates spliceosome activation via SNIP1-dependent RES complex recruitment
by Pavla Gajdušková & Igor Ruiz de Los Mozos & Milan Hluchý & Antonina Myšková & Kateřina Zábrady & Peter Maník & Neda Dragišić & Kateřina Hanáková & David Potěšil & Sara Bologna & Jiří Nováček & Caroline C. Friedel & Konstantinos Tripsianes & Zbyněk Zdráhal & Dalibor Blazek
- 1-21 Mapping rare protein-coding variants on multi-organ imaging traits
by Yijun Fan & Jie Chen & Zirui Fan & Julio Chirinos & Jason L. Stein & Patrick F. Sullivan & Rujin Wang & Ajay Nadig & David Y. Zhang & Shuai Huang & Zhiwen Jiang & Peter Yi Guan & Xinjie Qian & Ting Li & Haoyue Li & Zehui Sun & Marylyn D. Ritchie & Joan M. O’Brien & Walter Witschey & Daniel J. Rader & Tengfei Li & Hongtu Zhu & Bingxin Zhao
- 1-21 A massively parallel CRISPR-based screening platform for modifiers of neuronal depolarization
by Steven C. Boggess & Vaidehi Gandhi & Ming-Chi Tsai & Emily Marzette & Noam Teyssier & Joanna Yu-Ying Chou & Xiaoyu Hu & Amber Cramer & Lin Yadanar & Kunal Shroff & Claire G. Jeong & Celine Eidenschenk & Jesse E. Hanson & Ruilin Tian & Martin Kampmann
- 1-21 ASO therapy rescues NOTCH2NLC GGC repeat expansion-induced genomic damage, 3D chromatin structural abnormalities, and senescence
by Mengjie Li & Mibo Tang & Xiaoyan Hao & Zhengwei Hu & Dongrui Ma & Shuangjie Li & Chunyan Zuo & Zhiyun Wang & Yuanyuan Liang & Yanmei Feng & Chenwei Hao & Chen Wang & Huanyu Li & Yalan Yang & Yuemeng Sun & Shasha Qi & Chengyuan Mao & Yuming Xu & Qun Wang & De Yang & Ruwei Yang & Ziyao Zhou & Peilin Ji & Song Tan & Zaiqiang Zhang & Hao Chen & Albert R. La Spada & Changhe Shi
- 1-21 α-Synuclein aggregates induce mitochondrial damage and trigger innate immunity to drive neuron–microglia communication
by Ranabir Chakraborty & Stephanie Maya & Veronica Testa & Jara Montero-Muñoz & Takashi Nonaka & Masato Hasegawa & Antonella Consiglio & Chiara Zurzolo
- 1-21 Fidelity in co-diversified symbiosis
by Inès Pons & Marleny García-Lozano & Christiane Emmerich & Aftab Mahmood Ayas & Christine Henzler & Hagay Enav & Ruth E. Ley & Hassan Salem
- 1-21 HIF sustain a transcriptional regulatory circuit of EPAS1 expression in renal clear cell carcinoma
by Stephanie Naas & René Krüger & Steffen Grampp & Victoria Lauer & Andre Kraus & Julia Naas & Fabian Müller & Franziska Gsottberger & Mario Schiffer & Bernd Wullich & Arndt Hartmann & Marc P. Stemmler & Johannes Schödel
- 1-21 Robustly enhancing crop genomic prediction accuracy through ensemble learning and iterative optimization
by Zhou Yao & Liguang Wang & Li Zhu & Xinle Li & Qiqi Wu & Fan Wu & Guoshuai Wang & Wenyu Yang & Yingjie Xiao & Jianxiao Liu
- 1-21 Conserved and divergent gene regulatory networks for crop drought resistance
by Xianzhi Deng & Liangsheng Shi & Yu Wang & Han Qiao & Xin Wang & Jiateng Ma & Yufan Zhang & Yuanyuan Zha & Xiaolong Hu
- 1-21 MeCP2 gene dosage-dependent neurodevelopmentally restricted defects arise by aberrant activation of cell fate-determining bivalent genes
by Mirko Luoni & Michal Kubacki & Serena Gea Giannelli & Francesca Morosi & Claudia Di Berardino & Angelo Iannielli & Alessandro Sessa & Gaia Colasante & Emanuele Di Patrizio Soldateschi & Chiara Lanzuolo & Vania Broccoli
- 1-21 Molecular anatomy of PLK1 master docking motifs
by Long Ren & Arianna Esposito-Verza & Raphael Gasper & Marion E. Pesenti & Petra Janning & Franziska Müller & Carolin Koerner & Petra Geue & Sabine Wohlgemuth & Ingrid R. Vetter & Andrea Musacchio
- 1-21 Stenotrophomonas promotes gastrointestinal tumor progression via STING degradation in tumour cells and mitigated immune response
by Huolun Feng & Kunling Chen & Zhihui Xi & Baijin Xia & Xi Chen & Yiqin Huang & Zuda Huang & Jieqing Guo & Dandan Zhu & Fa Ling & Jianlong Zhou & Yuhan Zhang & Yucheng Zhang & Yongfeng Liu & Wenxing Zhang & Jiatong Lin & Zejian Lyu & Qunsheng Huang & Junjiang Wang & Tieying Hou & Jiabin Zheng & Fan Xing & Yong Li
- 1-21 Predicting individual differences of fear and cognitive learning and extinction
by C. A. Gomes & D. R. Bach & A. Razi & G. Batsikadze & S. Elsenbruch & H. Engler & T. M. Ernst & M. C. Fellner & C. Fraenz & E. Genç & A. Klass & F. Labrenz & S. Lissek & C. J. Merz & D. Metzen & A. Nostadt & R. J. Pawlik & J. E. Schneider & M. Tegenthoff & A. Thieme & O. T. Wolf & O. Güntürkün & H. H. Quick & R. Kumsta & D. Timmann & T. Spisak & N. Axmacher
- 1-21 Complex I protein NDUFB9 is a metabolic vulnerability in triple negative breast cancer brain metastases
by Mingxi Lin & Zhexu Wen & Cheng Zeng & Yizi Jin & Teng Zhou & Yuxin Yan & Shenglin Huang & Xin Hu & Xiaoxiang Guan & Xichun Hu & Jian Zhang
- 1-21 CD38⁺ endothelial remodeling marks spatially patterned vasculopathy in rapidly advancing periodontitis and peri-implantitis
by Quinn T. Easter & Khoa L. A. Huynh & Camila Schmidt Stolf & Jialiu Xie & Bruno F. Matuck & Akira Hasuike & Zabdiel Alvarado-Martinez & William S. Kim & Zhaoxu Chen & Apoena Aguiar Ribeiro & Nivedita Pareek & Andrea M. Azcarate-Peril & Di Wu & Renato Casarin & Kang I. Ko & Jinze Liu & Kevin M. Byrd
- 1-21 Endosome maturation is orchestrated by inside-out proton signaling through a Na+/H+ exchanger and pH-dependent Rab GTPase cycling
by YouJin Lee & Qing Ouyang & Li Ma & Morgan Fleishman & Hasib Aamir Riaz & Michael Schmidt & Jeffrey L. Dupree & Anupam Mondal & Priyesh Mohanty & Jeetain Mittal & Oliver Beckstein & David G. Lambright & Eric M. Morrow
- 1-21 Bacterial targeting of the neutrophil inhibitory receptor LILRB3 to evade antibody immunity
by Matevž Rumpret & Alexander L. Lewis Marffy & Ying Zhang & Esther van Woudenbergh & Sjors P. A. van der Lans & Xin Xu & Zuyi Fu & Yuxi Zhao & Erin A. Catton & Guillaume Paré & Felix McGregor & Owen B. Spiller & Maria J. Fernandes & Carla J. C. de Haas & Jos A. G. van Strijp & Nina M. van Sorge & Brian V. Geisbrecht & Alex J. McCarthy
- 1-21 Tonotopic specialization of MYO7A isoforms in auditory hair cells
by Sihan Li & Jinho Park & Tobey M. Phan & Giusy A. Caprara & Natchanon Sittipongpittaya & Gloria M. Sheynkman & Anthony W. Peng & Edward H. Egelman & Jonathan E. Bird & Jung-Bum Shin
- 1-21 Autophagic extracellular vesicles (AEVs) are distinct from exosomes and play crucial roles in viral infections
by Kedan Mao & Fangfang Huo & Hongqi Wei & Furong Wang & Sidong Xiong & Yuxuan Fu
- 1-21 A gut microbiome-kidney-heart axis predictive of future cardiovascular diseases
by Kanta Chechi & Rima Chakaroun & Antonis Myridakis & Sofia K. Forslund-Startceva & Sebastien Fromentin & Trine Nielsen & Judith Aron-Wisneswky & Eugeni Belda & Edi Prifti & Pierre Bel Lassen & Gwen Falony & Sara Vieira-Silva & Julien Chilloux & Kazuhiro Sonomura & Lesley Hoyles & Laura Martinez-Gili & Francesco Pallotti & Petros Andrikopoulos & Francesc Puig-Castellví & Romina Pacheco Tapia & Inés Castro-Dionicio & Hugo Roume & Nicolas Pons & Emmanuelle Le Chatelier & Benoit Quinquis & Nathalie Galleron & Magali Berland & Michael T. Olanipekun & Manyi Jia & Angelos Manolias & Bridget Holmes & Solia Adriouch & Matthias Blüher & Luis Pedro Coelho & Kévin Da Silva & Pilar Galan & Boyang Ji & Ana Luisa Neves & Christine Rouault & Joe-Elie Salem & Valentina Tremaroli & Tue H. Hansen & Nadja B. Søndertoft & Christian Lewinter & Helle K. Pedersen & Peter D. Mark & Jens P. Goetze & Lars Køber & Henrik Vestergaard & Torben Hansen & Jean-Daniel Zucker & Taka-Aki Sato & Serge Hercberg & Fredrik Bäckhed & Ivica Letunic & Jean-Michel Oppert & Jens Nielsen & Jeroen Raes & Ioanna Tzoulaki & Abbas Dehghan & Verena Zuber & Emmanuelle Bouzigon & Mark Lathrop & Parminder Raina & Philippe Froguel & Fumihiko Matsuda & Florence Demenais & Dominique Gauguier & Michael Stumvoll & Peer Bork & Oluf Pedersen & S. Dusko Ehrlich & Karine Clément & Marc-Emmanuel Dumas
- 1-21 Transgenic hookworm secretes anti-tetrodotoxin human single chain antibody
by Kumar Sachin Singh & Suman Bharti & Bruce A. Rosa & Mahdiyeh Bigham & Samuel C. Uzoechi & Young-Jun Choi & John C. Martin & Danielle Kemper & Slavica Pavlovic Djuranovic & Darren A. Pickering & Rachael Ryan & Bethany K. Bracken & Maria Elena Bottazzi & Eric C. Carnes & Wannaporn Ittiprasert & Matthew Moyle & Paul J. Brindley & Alex Loukas & Sergej Djuranovic & Makedonka Mitreva
- 1-21 Time-dependent bistability leads to critical slowing down during floral transition in Arabidopsis
by Gabriel Rodríguez-Maroto & Kang Wang & Pau Casanova-Ferrer & Martina Cerise & George Coupland & Pau Formosa-Jordan
- 1-21 Priming versus propagating: distinct immune effects of alpha- versus beta-particle emitting radiopharmaceuticals when combined with immune checkpoint inhibition in mice
by Caroline P. Kerr & Won Jong Jin & Peng Liu & Joseph J. Grudzinski & Carolina A. Ferreira & Hansel Comas Rojas & Alejandro J. Oñate & Ohyun Kwon & Meredith Hyun & Malick Bio Idrissou & René Welch Schwartz & Jessica M. Vera & Paul A. Clark & Adedamola Adeniyi & Maya Takashima & Amy K. Erbe & Amanda G. Shea & Maria Powers & Anatoly N. Pinchuk & Christopher F. Massey & Cynthia Choi & Reinier Hernandez & Bryan P. Bednarz & Irene M. Ong & Jamey P. Weichert & Zachary S. Morris
- 1-21 Signaling downstream of tumor–stroma interaction regulates mucinous colorectal adenocarcinoma apicobasal polarity
by Nicolas Pasquier & Meri Pelkonen & Elise Carraz-Billat & Aleksi Isomursu & Raphaël Merand & Hellyeh Hamidi & Jacques R. R. Mathieu & Jouni Härkönen & Gautier Follain & Christophe Desterke & Zoé Fusilier & Junel Solis & Irina Belaya & Pasi Kankaanpää & Valeria Barresi & Mohamed-Amine Bani & Johanna Protin & Jérôme Cartry & Sabrina Bedja & Olav M. Andersen & Klaus Elenius & Florent Peglion & Fanny Jaulin & Johanna Ivaska
- 1-21 Global remapping of the sensory homunculus emerges early in childhood development
by Raffaele Tucciarelli & Laura Bird & Zdenek Straka & Maggie Szymanska & Mathew Kollamkulam & Harshal Arun Sonar & Jamie Paik & Danielle Clode & Matej Hoffmann & Dorothy Cowie & Tamar R. Makin
- 1-21 Conducting polymer-stabilized nanozymes alleviate sepsis-induced myocardial injury by inhibiting iron accumulation and lipid peroxidation
by Tingting Wu & Ying Liu & Wei Wang & Rong Sun & Yanyan Wang & Jiangpeng Pan & Jingfei Zhu & Kelong Fan & Qiuran Xu & Wei Jiang
- 1-21 A pathogenic Tau mutation drives autophagy-lysosome dysfunction that limits Tau degradation in a model of frontotemporal dementia
by Farzaneh S. Mirfakhar & Jacob A. Marsh & Chihiro Sato & Kylie J. Schache & Miguel A. Minaya & Roland E. Dolle & Stephen C. Pak & Gary A. Silverman & David H. Perlmutter & Shannon L. Macauley & Celeste M. Karch
- 1-21 Annexing isothermal nucleotide amplification enables probe-guided amplification and direct detection at ambient temperature
by Ariana Human-McKinnon & Madisen Pyper & MiKenzee Frazier & Emily Plant & Harrison Piper & Tyler Archibald & Anindita Roy
- 1-21 Chondrocytes reprogram chromatin in hypoxic microenvironments to activate CADM1-AS1/HDAC1 complex-mediated anti-inflammation signals
by Weiyu Ni & Tianyuan Gu & Panyang Shen & Zixuan Mei & Yizheng Wu & Kamuran Yilamu & Nan Pan & Wentao Yang & Gang Liu & Yan Ma & Xiangqian Fang & Shunwu Fan & Haitao Zhang & Shuying Shen
- 1-21 Eye movements during free viewing to maximize scene understanding
by Shravan Murlidaran & Miguel P. Eckstein
- 1-21 Quiescent tumor cells shape the immunosuppressive microenvironment in pancreatic cancer
by B. McClellan & Q. Wang & K. Aung & W. Matsui
- 1-21 Tumor metabolic adaptation induced by L-asparaginase reveals a vulnerability to PARP1/2 inhibitor in B-cell lymphomas
by Anaïs Aussel & Ivan Nemazanyy & Ashaina Vandenberghe & Pauline Meola & Noémie Dorat & Rachel Paul & Lama Habbouche & Laurie Exposito & Nicolas Nottet & Virginie Petrilli & Edmond Chiche & Nicolas Mounier & Sandrine Marchetti & Cédric Chaveroux & Jean-Ehrland Ricci & Johanna Chiche
- 1-21 Hypoxia-induced metastatic heterogeneity in pancreatic cancer
by Pradeep Moon Gunasekaran & Qianqian Wang & Polina Guseva & Yoke-Chen Chang & Rajika Chauhan & Alexander Kley & Mengdie Xu & Gene Lee & Gregory Marshall & Siddharth Ghosh Roy & Yousef Masoudpoor & Oscar Li & Arthur Roberts & Kelly Watkins Walton & Lucyann Franciosa & Shafiq Bhat & Emmanuel Zachariah & Kishan Patel & Zhongren Zhou & Jian Cao & Wenjin Chen & Julie Zhouli Ni & Sam Guoping Gu & Cristina Montagna & Shin-Heng Chiou
- 1-21 Evolutionary remodeling of ubiquinone biosynthesis in Toxoplasma gondii reveals an essential bi-functional monooxygenase
by Baihetiya Baierna & Taufiq Rahman & Scott Latimer & Gilles J. Basset & Silvia N. J. Moreno
- 1-21 Decoding immunotherapy response through computational modeling
by Bingrui Li & Ruihan Luo & Kexin Huang & Jiajia Liu & Weiling Zhao & Xiaobo Zhou
- 1-21 Developmental molecular signatures define de novo cortico-brainstem circuit for skilled forelimb movement
by Julia Kaiser & Payal Patel & Sam Fedde & Alexander Lammers & Matthew Kenwood & Asim Iqbal & Mark P. Goldberg & Vibhu Sahni
- 1-21 dHyperCas12a enables multiplexed CRISPRi screens
by Schuyler M. Melore & Christian D. McRoberts Amador & Marisa C. Hamilton & Charles A. Gersbach & Timothy E. Reddy
- 1-21 Pregnancy promotes tumor metastasis through adenosine-induced immunosuppressive neutrophils in pre-metastatic microenvironment
by Chen Chen & Jiahong Shi & Yutiantian Lei & Qian Wang & Peihai Cao & Dairu Hou & Mengdi Huang & Ruiying Wang & Qiuyu Mu & Tingting Lv & Rui Jia & Mingjun Si & Dingge Jiang & Lei Li & Zhixuan Cai & Yakun Huang & Jiahao Sun & Lianying Jiao & Zhengtao Xiao & Yuhan Li & Binxian Wang & Shan Huang & Wenqian Du & Lu Bai & Jinlu Ma & Suxia Han & Baojun Zhang & Chen Lin & Hui Guo & Xiangjiao Meng & Yuzhu Hou
- 1-21 D-π-A sensitized carbon dots as long-lived type-I/Ⅱ photosensitizers for NIR-excited hypoxia-regulated photodynamic therapy
by Zhenlin Zhang & Lang Yan & Weiwei Li & Jinyan Hu & Yang Wang & Hongjing Dou & Dengyu Pan & Longxiang Shen & Sheng Shi & Bijiang Geng
- 1-21 USP24 is a cross-reactive DUB targeting MOV10 to regulate IFN-I production
by Rishov Mukhopadhyay & Simeon D. Draganov & Timo Oosenbrug & Jimmy J. L. L. Akkermans & Marjolein Kikkert & Klaus-Peter Knobeloch & Günter Fritz & María Guzmán & Sonia Zuñiga & Robbert Q. Kim & Annemarthe G. van der Veen & Benedikt M. Kessler & Adán Pinto-Fernández & Paul P. Geurink & Aysegul Sapmaz
- 1-21 Natural degradation of RNA polymerase II is essential for oocyte chromatin reorganization and maternal-to-zygotic transition
by Jing Wang & Wang Li & Jing Guo & Xiaoming Xu & Ge Lin & Bin Li & Chun So
- 1-21 Iron deficiency induces maturation-dependent loss of pancreatic β-cells
by Annelore Van Mulders & Lien Willems & Sophie Coenen & Stephanie Bourgeois & Xiaoyan Yi & Yue Tong & Gunter Leuckx & Yves Heremans & Julie Pierreux & Laure Degroote & Toshiaki Sawatani & Chiara Vinci & Gamze Ates & Ann Massie & Françoise Carlotti & Eelco de Koning & Thomas Mandrup-Poulsen & Clara Zelinsky & Steven Goderis & Bart Ghesquière & Raphael Scharfmann & Miriam Cnop & Nico De Leu & Willem Staels
- 1-21 Proviral NUP153 binding to viral proteins and RNA regulates structural–nonstructural protein ratios in orthoflavivirus infection
by Marie B. A. Peters & Richard Lindqvist & Eszter Kassa & Wai-Lok Yau & Pallabi Sengupta & Isabell Niedermoser & Gisa Gerold & Nasim Sabouri & Ylva Ivarsson & Richard Lundmark & Anna K. Överby
- 1-21 Urolithin A activates aryl hydrocarbon receptor-NLRP6-mediated pathways in intestinal epithelial cells to modulate mucosal immunity and strengthen gut barrier integrity
by Sweta Ghosh & Zachary M. Vanwinkle & Sobha Rani Bodduluri & Subir Kumar Juin & Mahendar Kadari & Ankita Singh & Gerald W. Dryden & Matthew B. Lawrenz & Thirumala-Devi Kanneganti & Shesh N. Rai & Misty Good & Pawan Kumar & Bodduluri Haribabu & Venkatakrishna Rao Jala
- 1-21 Cross-ancestry comparison of aptamer and antibody protein measures
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