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Content
December 2026, Volume 17, Issue 1
- 1-24 Transcription factor 19 modulates fatty acid elongation and unfolded protein response to attenuate palmitic acid-induced hepatic dysfunction
by Atanu Mondal & Arnab Chakraborty & Sandhik Nandi & Vipin Singh & Siddhesh S. Kamat & Chandrima Das
- 1-24 Saccharomyces cerevisiae reduces vulvovaginal candidiasis severity through modulation of fungal pathogenicity and inflammatory responses
by Mart Sillen & Dania El Abyad & Nina Vreys & Silke Baldewijns & Ilse Palmans & Odessa Van Goethem & Kar On Cheng & Greetje Vande Velde & Dolly E. Montaño & Nele Berghmans & Mieke Gouwy & Agustin R. Sharpe & Lies De Groef & Axel Dietschmann & Paul Vandecruys & Sarah Lebeer & Liesbeth Demuyser & Mark S. Gresnigt & Patrick Van Dijck
- 1-24 FidlTrack: high-fidelity structure-aware single particle tracking resolves intracellular molecular motion in organelles sensing APP processing
by Pierre Parutto & Yutong Yuan & Valentina Davì & Roger Pons-Lanau & Svenja Ebeling & Karnika Gupta & Francesca Bottanelli & Maria F. Garcia-Parajo & Felix Campelo & Clemens F. Kaminski & Joseph E. Chambers & Jonathon Nixon-Abell & Edward Avezov
- 1-24 Double strand breaks drive toxicity in a Huntington’s disease mouse model with or without somatic expansion
by Aris A. Polyzos & Ana Cheong & Jung Hyun Yoo & Lana Blagec & Zachary D. Nagel & Cynthia T. McMurray
- 1-24 Triose phosphate isomerase 1 remodels mitochondrial cristae ultrastructure to rewire microglial immunometabolism against ischemic stroke
by Xiao-Wen Zhang & Xiao-Ming Ye & Ran Wang & Yong-Dong Guo & Ling Li & Yang Chen & Ting-ting Liu & Xiao-Qing Zhou & Yu-Qi Wang & Zhong-Yao Li & Zhi-Yuan Lu & Zhi-Yong Du & Wei Zhou & Bo Han & Peng-Fei Tu & Qi-Xin Chen & Chun-Hong Zheng & Ke-Wu Zeng
- 1-24 Reverse engineering of BNIP3 identifies a mitochondrial protective peptide
by Ulrike B. Hendgen-Cotta & Anna Roth & Christine Beuck & Daniel Messiha & Stephan Settelmeier & Shah Bahrullah Shah & Sebastian Korste & Kenny Bravo-Rodriguez & Mike Blueggel & Feyza Cansiz & Luiza Martins Nascentes Melo & Jonas Roesler & Sven W. Meckelmann & Oliver J. Schmitz & Farnusch Kaschani & Markus Kaiser & Sonja Esfeld & Omar El Bounkari & Jürgen Bernhagen & Sophie Brameyer & Kirsten Jung & Linda-Isabell Schmitt & Markus Leo & Tim Hagenacker & Matthias Totzeck & Thomas Minor & Michael Ehrmann & Alpaslan Tasdogan & Peter Bayer & Tienush Rassaf
- 1-24 A centrally positioned cluster of multiple centrioles in antigen-presenting cells fosters T cell activation
by Isabel Stötzel & Ann-Kathrin Weier & Apurba Sarkar & Subhendu Som & Luisa Bach & Peter Konopka & Eliška Miková & Shaunak Ghosh & Jan Böthling & Mirka Homrich & Laura Schaedel & Uli Kazmaier & Konstantinos Symeonidis & Stefan Ebner & Philip Weidner & Zeinab Abdullah & Felix Meissner & Stefan Uderhardt & Miroslav Hons & Dirk Baumjohann & Raja Paul & Heiko Rieger & Eva Kiermaier
- 1-24 Enzyme-responsive peptide dendron nanoassemblies for targeting and eliminating intracellular drug-resistant bacteria
by Qi Tang & Peng Tan & Chenlong Zhou & Guanghui Zhao & Shuaikang Yang & Yucheng Zhang & Tao Wang & Zhenduo Chen & Xi Ma
- 1-24 15-LOX-catalytic bias towards ether-(alkenyl)-ETE-PEs oxidation bestows selectivity of PRO-ferroptotic cell death signaling
by Yulia Y. Tyurina & Karolina Mikulska-Ruminska & Vladimir A. Tyurin & Brian A. Kleiboeker & Alexander A. Kapralov & Ayumi Hashimoto & Louis J. Sparvero & Haider H. Dar & Mert Akdogan & Kazuhiro Yamada & Jinming Zhao & Taha Kelestemur & Ecem Saritas & Sviatlana N. Samovich & Theodore R. Holman & Yuri L. Bunimovich & Yulia Nefedova & Dmitry I. Gabrilovich & Sally E. Wenzel & Ivet Bahar & Valerian E. Kagan & Hülya Bayır
- 1-24 TFEB degradation is regulated by an IKK/β-TrCP2 phosphorylation-ubiquitination cascade
by Yan Xiong & Jaiprakash Sharma & Meggie N. Young & Wen Xiong & Ali Jazayeri & Karl F. Poncha & Ma. Xenia G. Ilagan & Qing Wang & Bei Gao & Hui Zheng & Nicolas L. Young & Marco Sardiello
- 1-24 Large-scale multi-omics profiling reveals environmental and evolutionary drivers of fungal phylogeographic and metabolic diversity
by Huali Xie & Jie Hu & Xiulan Zhao & Jianwei Chen & Xiaofeng Yue & Changhao Zhou & Jorge C. Navarro-Muñoz & Jun Jiang & Xiaoqian Tang & Fang Zhao & E. Anne Hatmaker & Antonis Rokas & Amelia E. Barber & Milton T. Drott & Nancy P. Keller & Qi Zhang & Justin J. J. van der Hooft & Marnix H. Medema & Peiwu Li
- 1-24 Identification of Chlamydia pneumoniae and NLRP3 inflammasome activation in Alzheimer’s disease retina
by Bhakta Prasad Gaire & Yosef Koronyo & Jean-Philippe Vit & Alexandre Hutton & Lalita Subedi & Dieu-Trang Fuchs & Natalie Swerdlow & Altan Rentsendorj & Saba Shahin & Daisy Martinon & Edward Robinson & Alexander V. Ljubimov & Julie A. Schneider & Lon S. Schneider & Debra Hawes & Stuart L. Graham & Vivek K. Gupta & Mehdi Mirzaei & Keith L. Black & Jesse G. Meyer & Moshe Arditi & Timothy R. Crother & Maya Koronyo-Hamaoui
- 1-24 Combinatory differentiation of human induced pluripotent stem cells generates functional thymic epithelium driving dendritic cell and CD4/CD8 T cell development
by Nathan Provin & Manon d’Arco & Antoine Le Bozec & Erwan Kervagoret & Alexandre Bruneau & Lucas Brusselle & Cynthia Fourgeux & Jeremie Poschmann & Philippe Hulin & Pierre Maminirina & Olivier Baron & Xavier Saulquin & Carole Guillonneau & Laurent David & Matthieu Giraud
- 1-24 LSD1 inhibitor, TAS1440, disrupts INSM1-LSD1 complex activating tumor-suppressive pathways via transcriptional reprogramming in neuroendocrine SCLC
by Takumitsu Machida & Yingbo Gong & Sayaka Tsukioka & Atsushi Onodera & Akitoshi Nakayama & Naoko Hashimoto & Takahiro Fuchigami & Motoi Nishimura & Tomohiro Ogino & Ryota Kurimoto & Yasufumi Uematsu & Hidemi Suzuki & Hongye Yu & Mingyang Chen & Masataka Yokoyama & Ikki Sakuma & Yuki Taki & Takashi Kono & Takashi Miki & Shinichiro Motohashi & Yusuke Kawashima & Osamu Ohara & Satoshi Yamashita & Tatsuya Suzuki & Ryo Hatanaka & Yasuo Kodama & Shuichi Ohkubo & Tomoaki Tanaka
- 1-24 Molecular pathogenesis and gene therapy-based intervention of GTPBP3-related mitochondrial disease
by Yong Zhang & Shi-Ying Yao & Jing Li & Tingting Yu & Hao Liu & Nanlin Zhu & Gui-Xin Peng & Wen-Qiang Zheng & Chun-Rui Ma & En-Duo Wang & Cui Song & Xiao-Long Zhou
- 1-24 Palmitic acid-triggered B7H3 palmitoylation promotes immune escape
by Zejun Rao & Changsheng Huang & Qi Wu & Mao Li & Anyi Liu & Tong Zhu & Wangshuo Yang & Lanlan Yin & Shengyu Zhu & Xiaowei She & Chengxin Yu & Lang Liu & Pengcheng Li & Yucong Bai & Dongjing Zhang & Tianci Xie & Xiang Liu & Lu Liu & Feng Xu & Guihua Wang & Junbo Hu & Xuelai Luo
- 1-24 PDK4 drives abdominal aortic aneurysm by promoting smooth muscle cell metabolic reprogramming and NLRP3-mediated pyroptosis
by Li Zhao & Xuefeng Lin & Zhengqiang Zhu & Ranxin Liu & Lingna Zhao & Xuekun Wu & Mengru Zheng & Rihua Huang & Pengyu Zhou & Fangze Huang & Deshen Liu & Chuanjie Niu & Xiaoxia He & Zean Wang & Xin Li & Jiale Li & Shengping He & Jun Lu & Shaoyi Zheng & Jiaguo Zhou & Qinbao Peng & Xiu Liu
- 1-24 Modulation of Nudt21 levels reveals dose-dependent roles of alternative polyadenylation in tissue regeneration
by Nikolaos Tsopoulidis & Masaki Yagi & Justin Brumbaugh & Shinya Ito & Víctor López-Soriano & Robert Morris & Yoseop Yoon & Kathleen A. Messemer & Kuan-Hung Lin & Eric F. Zaniewski & Rebecca Gorelov & Aaron J. Huebner & Amy J. Wagers & Hanno Hock & Günter Kramer & Bernd Bukau & Michael S. Hoetker & Yongsheng Shi & Wilhelm Haas & Konrad Hochedlinger
- 1-24 Deficiency of lysosomal TMEM175 in myeloid macrophages exerts anti-tumor immunity via inflammasome and cross-presentation pathway
by Ziqi Zhang & Xue li & Tianqi Lu & Jingyun Yang & Xuejiao Han & Zhenfei Bi & Jingwen Luo & Aqu Alu & Weiqi Hong & Siyuan Chen & Lei Chen & Yuan Cheng & Xuemei He & Chenjing Zhu & Manni Wang & Qingfang Li & Yang Wang & Lu Li & Hong Lei & Jie Lan & Jia Geng & Yuquan Wei & Xiawei Wei
- 1-24 Lactate mitochondrial oxidation drives stemness potential in metastatic breast cancer
by Jia-Jia Zhang & Ruo-Fei Tian & Chang-Geng Song & Rui Liu & Duo He & Gai-Qin Zhang & Xin-Yu Fan & Zi-Chuan Duan & Kun Zhang & Tian-Jiao Zhang & Ya-Tong Chen & Jian Zhang & Ke Wang & Ju-Mei Zhao & Xiang-Min Yang & Zhi-Nan Chen & Ling Li
- 1-24 Functional KCC2 expression marks an evolutionarily conserved population of early-maturing interneurons in the perinatal cortex
by Rakenduvadhana Szrinivasan & Kalevi Trontti & Rémi Mathieu & Tangra Draia-Nicolau & Genevieve Chazal & Säde Loukasmäki & Silvana Bodington Celma & Kaia Achim & Pavel Uvarov & Stanislav Khirug & Anastasia Ludwig & Sari E. Lauri & Antoine de Chevigny & Olli Pietiläinen & Claudio Rivera
- 1-24 Mosaic partial epidermal reprogramming remodels neighbors and niches to refine skin homeostasis and repair
by Minjun Kwak & Eunjun Choi & Yemin Jo & Boa Kim & Chaeryeong Lim & Jooyoung Lim & Yoon Ha Choi & Jung Hyun Lee & Kee-Pyo Kim & Bon-Kyoung Koo & Jong Kyoung Kim & Sekyu Choi
- 1-24 Ponatinib inhibits LCK and PI3K signaling and promotes CD8+ T stem cell memory cell development
by Yuki Okuhiro & Sachiko Ito & Keisuke Watanabe & Yue Yan & Kazuhiro Kumagai & Takahiko Sato & Yasuhiro Kojima & Yuki Fujioka & Naoto Takahashi & Hitoshi Kiyoi & Yuka Maeda & Takuma Kato & Hiroyoshi Nishikawa
- 1-24 Spliceosome induction is a druggable dependency of RAS-driven senescence and cancer
by Verena Wagner & Laura Bousset & Mariana Ascensão-Ferreira & Bin Sun & José Efren Barragan Avila & Alexandre Kaizeler & Rita Martins-Silva & Mohammad Rahbari & Mirian Fernández-Vaquero & Scott Haston & Michele Tinti & Joaquim Pombo & Sanjay Khadayate & Susanne Roth & Christian M. Schürch & Juan Pedro Martínez-Barbera & Anat Bahat & Keng Boon Wee & Jennifer P. Morton & Nisar Malek & Andrew J. Innes & Santiago Vernia & Nuno L. Barbosa-Morais & Suchira Gallage & Mathias Heikenwalder & Jesús Gil
- 1-24 DKC1 promotes colorectal cancer progression and therapy resistance by dysregulating sphingolipid biosynthesis
by Umar K. Khan & Ayush Goel & Shivansh Nigam & Nazia Chaudhary & Ayush Praveen & Anjan Roy & Fabeha Fatima & Dilpreet K. Sawhney & Afiya Dalwai & Akshay Shendre & Shannon Carskadon & Anjali Bajpai & Abhimanyu Kapoor & Anjali Tewari & Abhijit Chandra & Avanish Saklani & Sorab N. Dalal & Nallasivam Palanisamy & Bushra Ateeq
- 1-24 The biological role of local and global fMRI BOLD signal variability in multiscale human brain organization
by Giulia Baracchini & Yigu Zhou & Jason da Silva Castanheira & Justine Y. Hansen & Can Fenerci & Roni Setton & Jenny R. Rieck & Gary R. Turner & Cheryl L. Grady & Bratislav Misic & Jason S. Nomi & Lucina Q. Uddin & R. Nathan Spreng
- 1-24 Decidualization-empowered ECM hydrogel integrating sustained Tβ4 release drives endometrial regeneration in intrauterine adhesions
by Yuxiang Liang & Zhaowei Yu & Shaobo Du & Yuqian Guo & Jing Li & Yujia Yan & Shanshan Jin & Wenjing Liang & Mengyuan Li & Ning Jin & Jiao Yang & Zhiwei Peng & Zhaoyang Chen & Hailan Yang & Zhizhen Liu & Qizhi Shuai & Liping Li & Jun Xie
- 1-24 Neural circuit models for evidence accumulation through choice-selective sequences
by Lindsey S. Brown & Jounhong Ryan Cho & Scott S. Bolkan & Edward H. Nieh & Manuel Schottdorf & David W. Tank & Carlos D. Brody & Ilana B. Witten & Mark S. Goldman
- 1-24 Guardian ubiquitin E3 ligases target cancer-associated APOBEC3 deaminases for degradation to promote human genome integrity
by Irene Schwartz & Valentina Budroni & Mathilde Meyenberg & Zuzana Hodakova & Harald Hornegger & Kathrin Hacker & Siegfried Schwartz & Daniel B. Grabarczyk & Julian F. Ehrmann & Sara Scinicariello & David Haselbach & Jörg Menche & Tim Clausen & G. Elif Karagöz & Gijs A. Versteeg
- 1-24 Single-cell spatial map of cis-regulatory elements for disease-related genes in the macaque cortex
by Juan Meng & Cheng Chen & Zhiyong Zhu & Yongkang Sun & Yiming Huang & Kaijie Hu & Jiqiang Fu & Luyan Wu & Ling Li & Yiqin Bai & Tianyi Fei & Zhen Liu & Chao Li & Zhiming Shen & Longqi Liu & Chengyu Li & Tao Song & Cirong Liu & Muming Poo & Shiping Liu & Ying Lei & Yidi Sun
- 1-24 Perivascular adipose single-cell atlas identifies CD55+ adipose-derived stem cells as vascular remodeling regulators in atherosclerosis
by Junye Chen & Kang Li & Jiang Shao & Song Mei & Zhichao Lai & Hongmei Zhao & Xiaohan Duan & Yunfei Xue & Xingqi Xiao & Yuyao Feng & Zhiwei Li & Zhan Zhu & Keqiang Shu & Deqiang Kong & Yiyun Xie & Leyin Xu & Chaonan Wang & Yanan Liu & Ziyan Xie & Yixuan Huang & Xinlei Zhang & Jing Wang & Peng Zhang & Bao Liu
- 1-24 DxDirector: an agentic large language model driving the full-process clinical diagnosis
by Shicheng Xu & Xin Huang & Zihao Wei & Liang Pang & Huawei Shen & Xueqi Cheng
- 1-24 Multi-omic identification of key transcriptional regulatory programs during endurance exercise training in rats
by Gregory R. Smith & Bingqing Zhao & Malene E. Lindholm & Archana Raja & Mark Viggars & Hanna Pincas & Nicole R. Gay & Yifei Sun & Sindhu Vangeti & Yongchao Ge & Venugopalan D. Nair & James A. Sanford & Mary Anne S. Amper & Mital Vasoya & Kevin S. Smith & Irene Ramos & Stephen B. Montgomery & Elena Zaslavsky & Sue C. Bodine & Karyn A. Esser & Martin J. Walsh & Michael P. Snyder & Stuart C. Sealfon
- 1-24 Bidirectional regulation of social memory by two distinct types of GABAergic neurons in the lateral septum
by Li Zhang & Mengbing Huang & Chao-Liang Ye & Zhiwei Tang & Mingrui Xu & Yuan Wang & Ting Wang & Shu Luo & Rui Ji & Chang Yu & Hongyan Luo & Peng Cao & Qing-Feng Wu & Man Jiang
- 1-24 The transcription factor HHEX maintains glucocorticoid levels and protects adrenals from androgen-induced lipid depletion
by Typhanie Dumontet & Kaitlin J. Basham & Micah C. Foster & Emma Silverman & Kyle A. Heard & Dominque Johnson & Chaelin Lee & Samuel W. Plaska & David T. Breault & David Penton & Felix Beuschlein & Adina F. Turcu & Christopher R. LaPensee & Antonio Marcondes Lerario & Gary D. Hammer
- 1-24 Planar, spiral, and concentric traveling waves distinguish behavioral states in human memory
by Anup Das & Erfan Zabeh & Bard Ermentrout & Joshua Jacobs
- 1-24 AI-guided CAR designs and targeted pathway modulation to enhance multi-antigen CAR T cell durability and overcome antigen escape
by Mohammad Sufyan Ansari & Varnit Chauhan & Aashi Singh & Areej Akhtar & Nisha Chaudhary & Reegina Tyagi & Divya & Kashif Husain & Sheetal Sharma & Ruquaiya Alam & Md Shakir & Mehak Pracha & Samreen Anjum & Mohd Nadeem & Prial Taneja & Md Imam Faizan & Iqbal Azmi & Aditya Ramdas Iyer & Pragya Gupta & Mehwish Nafiz & Shayan Ali & Insha Mohi Uddin & Momina Javid & Zahoor Ahmad Bhat & Hamenth Kumar Palani & Amit Kumar Srivastava & Ulaganathan Mabalirajan & Vikram Mathews & Mohammad Husain & Sivaprakash Ramalingam & Gaurav Kharya & Tanveer Ahmad
- 1-24 2′-O-methylation-dependent installation of N2-methylguanosine in the U6 internal stem loop facilitates efficient spliceosome assembly
by Nicole Kleiber & Jonny Petrosyan & Maria Greve & Chairini C. Thomé & Olexandr Dybkov & Laurianne L. E. Tay & Luisa M. Welp & Philipp Hackert & David Touboul & Holger Stark & Markus T. Bohnsack & Henning Urlaub & Lydia Herzel & Marc Graille & Claudia Höbartner & Katherine E. Bohnsack
- 1-24 HR3/RORα-mediated cholesterol sensing regulates TOR signaling
by Mette Lassen & Keith Pardee & Ivan Bradic & Lisa H. Pedersen & Olga Kubrak & Nadja Ahrentløv & Sebastian Clancy & Takashi Koyama & Aleksandar Necakov & Suya Liu & Arnis Kuksis & Gilles Lajoie & Aled Edwards & Aurelio A. Teleman & Martin R. Larsen & Henry M. Krause & Michael J. Texada & Kim Rewitz
- 1-24 Efficient high-precision transgene knock-in by Recombinases (Redα/β)-enhanced DNA integration-CRISPR-Cas9 (RED-CRISPR)
by Wenqing Li & Senquan Liu & Xiaoyu Fang & Jiaqi Zou & Qin Jiang & Xiaolin Min & Xiaoli Zhu & Yuzhu Cao & Xiaoxiao Gao & Wenjie Han & Muhammad Azhar & Xuemei Xing & Fudong Li & Youming Zhang & Hongbin Liu & Linzhao Cheng & Chengkun Wang & Jianqiang Bao
- 1-24 Inhibition of TGF-β signaling in microglia stimulates hippocampal adult neurogenesis and reduces anxiety-like behavior in adult mice
by Kierra Ware & Joshua Peter & Jake Yazell & Christina Thapa & Aleksandr Taranov & Alicia Bedolla & Claire Distel & Sven Lammich & Regina Feederle & Alice Sülzen & Shane Liddelow & Krishna Roskin & Yu Luo
- 1-24 Cell type-specific functions of the PBAF chromatin-remodeling complex in neuronal diversification
by Anthony Osuma & Honorine Destain & Jessica Mann & Yinan Li & Seth R. Taylor & Manasa Prahlad & Ian Q. Weigle & Filipe Marques & Natalie Grace Schulz & Laura D. Mathies & Priota Islam & André E. X. Brown & Jayson J. Smith & Paschalis Kratsios
- 1-24 Camouflaged nanorobots target and regulate macrophage subcellular organelle crosstalk patterns to promote neural regeneration
by Qiangqiang Guo & Wei Wang & Xinzhao Jiang & Jincheng Tang & Feng Cai & Wenbo Wang & Lichen Zhang & Ziang Li & Yiyang Huang & Jie Wu & Liang Zhou & Haochen Jiang & Yiwei Zhu & Guhao Cai & Ziyu Lin & Yong Gu & Xuesong Zhu & Liang Chen & Kun Xi
- 1-24 Polycomb chromatin topology enables long-range enhancer recruitment during craniofacial development
by Yousra Ben Zouari & Onkar Joshi & Adwait Salvi & Sandra Kessler & Sebastien Ducret & Fiona Ross & Sjoerd J. B. Holwerda & Nathalie Vilain & Soujanya Mamilla-Sanivaram & Sebastien Smallwood & Hubertus Kohler & Michael B. Stadler & Maryline Minoux & Filippo M. Rijli
- 1-25 SuperARC: a test for artificial superintelligence based on compressed modelling, recursive prediction and problem complexity
by Alberto Hernández-Espinosa & Luan Ozelim & Felipe S. Abrahão & Hector Zenil
- 1-25 Histone methylation defines c-Jun/Sox2/Hif1α axis that controls stemness and tumor progression in squamous cell carcinoma
by Darshan Mehta & Akshay Paradkar & Bharat Rekhi & Prakash Nayak & Bhabani Mohanty & Pradip Chaudhari & Poonam Gera & Swapnil Rane & Pankaj Chaturvedi & Sanjeev K. Waghmare
- 1-25 Eukaryote initiation factor 6 modulates small-cell lung carcinoma plasticity via the integrin-FAK signaling axis
by Haoning Peng & Zhile Wang & Mengyao Wang & Zheyu Ding & Kaixiu Li & Yuqing Wang & Xuejiao Yu & Siyang Song & Yulan Deng & Yi Liu & Qiang Pu & Lu Li & Michael Cerezo & Weiya Wang & Lunxu Liu & Shensi Shen
- 1-25 RanBP2-dependent annulate lamellae drive nuclear pore assembly and nuclear expansion
by Junyan Lin & Arantxa Agote-Aran & Yongrong Liao & Mehdi Cloarec & Leonid Andronov & Rafael L. Schoch & Paolo Ronchi & Victor Cochard & Rui Zhu & Erwan Grandgirard & Xiaotian Liu & Marianne Victoria Lemée & Charlotte Kleiss & Christelle Golzio & Marc Ruff & Guillaume Chevreux & Yannick Schwab & Bruno P. Klaholz & Izabela Sumara
- 1-25 An in vivo and in vitro spatiotemporal profile of human midbrain development
by Dimitri Budinger & Pau Puigdevall & George T. Hall & Charlotte Roth & Theodoros Xenakis & Elena Marrosu & Julie Jerber & Alessandro Di Domenico & Francesca Picco & Helena Kilpinen & Sergi Castellano & Manju A. Kurian & Serena Barral
- 1-25 Sequential transcriptional waves and NF-κB-driven chromatin remodeling direct drug-induced dedifferentiation in cancer
by Yapeng Su & Chunmei Liu & Xiang Lu & Hui-Yu Chuang & Guideng Li & Shiqun Shao & Yan Kong & Jihoon W. Lee & Rachel H. Ng & Stephanie Wong & Lidia Robert & Charles Warden & Victoria Liu & Jie Chen & Zhuo Wang & Guangrong Qin & Yin Tang & Hanjun Cheng & Alphonsus H. C. Ng & Daniel Chen & Songming Peng & Min Xue & Dazy Johnson & Yu Xu & Jinhui Wang & Xiwei Wu & Ilya Shmulevich & Qihui Shi & Raphael Levine & Antoni Ribas & David Baltimore & Jun Guo & James R. Heath & Wei Wei
- 1-25 Accelerating Leigh syndrome drug discovery through deep learning screening in brain organoids
by Carmen Menacho & Satoshi Okawa & Iris Álvarez-Merz & Annika Wittich & Mikel Muñoz-Oreja & Pawel Lisowski & Mario López Martín & Tancredi Massimo Pentimalli & Shiri Zakin & Mathuravani Thevandavakkam & Caleb Jerred & Selene Lickfett & Laura Petersilie & Agnieszka Rybak-Wolf & Annette Seibt & Diran Herebian & Gizem Inak & Susanne Brodesser & Andrea Zaliani & Barbara Mlody & Justin Donnelly & Kasey Woleben & Francesc Xavier Soriano & Jose C. Fernandez-Checa & Natascia Ventura & Sidney Cambridge & Ertan Mayatepek & Antonella Spinazzola & Markus Schuelke & Nikolaus Rajewsky & Andrea Rossi & Alex Peralvarez-Marin & Felix Distelmaier & Ethan Perlstein & Ian J. Holt & Emma Puighermanal & Ole Pless & Christine R. Rose & Antonio Del Sol & Alessandro Prigione
- 1-25 Mechano-metabolic feedback connects tissue fluidity to mitochondrial DNA–dependent immunity in breast cancer
by Andrea Palamidessi & Emanuela Frittoli & Monica Corada & Emanuele Martini & Leonardo Barzaghi & Chiara Milanese & Galina V. Beznoussenko & Alessandro Lazzarin & Edoardo N. Bellini & Alexander A. Mironov & Zeno Lavagnino & Serena Magni & Sara Barozzi & Dario Parazzoli & Laura Tizzoni & Valentina Dall’Olio & Valeria Cancila & Patrizia Romani & Melody Di Bona & Renata Zobalova & Stepana Boukalova & Mattia Rediti & Pier G. Mastroberardino & Jiri Neuzil & Marco Foiani & Sirio Dupont & Claudio Tripodo & Giorgio Scita
- 1-25 Disturbances of paraventricular thalamic nucleus neurons in bipolar disorder revealed by single-nucleus analysis
by Masaki Nishioka & Mie Sakashita-Kubota & Kouichirou Iijima & Yukako Hasegawa & Mizuho Ishiwata & Kaito Takase & Ryuya Ichikawa & Naguib Mechawar & Gustavo Turecki & Tadafumi Kato
- 1-25 Dynamic partitioning of a critical elongation factor between LEC and SEC regulates cellular snRNA and proliferation-related mRNA transcription
by Arijit Nandy & Sambit Dalui & Prathama Talukdar & Poushali Chakraborty & Gaurav Bhagat & Ekjot Kaur Minhas & Srerupa Roy & Abhishake Lahiri & Venkatesha Basrur & Debabrata Biswas
- 1-25 Energy-sensing molecule RORγ regulates cholesterol metabolism and immune signaling in diabetic kidney disease and aging
by Zhen Liang & Jiaqing Xiang & Guangyan Yang & Xiaomai Liu & Lixing Li & Yanchun Li & Yan Lu & Lin Kang & Yuanli Chen & Chuanrui Ma & Shu Yang
- 1-25 An atlas of human siglecs integrates expression, affinity, and cis/trans sialoglycan recognition profiles
by Shani Leviatan Ben-Arye & Edward N. Schmidt & Zeinab Jame-Chenarboo & Claire Guetta-Oz & Fahima Mozaneh & Jaesoo Jung & Kelli A. McCord & Ronit Rosenfeld & Kan Zhong & Hongzhi Cao & Hai Yu & Xi Chen & Lori J. West & Matthew S. Macauley & Vered Padler-Karavani
- 1-25 Distinct modes of dopamine modulation on striatopallidal synaptic transmission
by Youngeun Lina Lee & Maria Reva & Ki Jung Kim & Hyun-Jin Kim & Yemin Kim & Eunjeong Cho & Minseok Jeong & Youngjong Kwak & Kyungjae Myung & Yulong Li & Seung Eun Lee & Dong Pyo Jang & C. Justin Lee & Christian Lüscher & Jae-Ick Kim
- 1-25 Sprayable nanozyme hydrogel epigenetically remodels inflammation for diabetic wound regeneration
by Amal George Kurian & Jeong-Hui Park & Shanika Karunasagara & Archita Gupta & Shreyas Kumar Jain & Tanza Baby & Ueon Sang Shin & Sak Lee & Buuvee Bayarkhangai & Rajendra K. Singh & Jung-Hwan Lee & Kam W. Leong & Hae-Won Kim
- 1-25 GCN5 drives MASLD progression through LXRα/SREBP1c signaling pathway–mediated de novo lipogenesis
by Hai-Tao Xiao & Peng Song & Jing Jin & Yong-Dan Wang & Yin-Yue Xu & He Wu & Xue-Xue Shao & Qi-Feng Gan & Jian He & Yan-Rong Wen & Jing Zhu & Bao-Yi Chen & Ping Zhou & Li-Na Lai & Hua Yang & Ping Li & Zu-Guo Zheng
- 1-25 An intralayer microcircuit in the temporal association cortex underlies sensory-induced escape in mice
by He Li & Jiajia Chen & Wen Zhong & Na Lian & Yumei Huang & Linhui Yao & Peiran Yin & Ziyi Xu & Xiaoxia Qin & Jie Tan & Yingying Zeng & Jinhua Liu & Zhongju Xiao
- 1-25 A decoupling strategy toward spatiotemporal regulation and biomechanical transmission of sandwiched scaffold for osteochondral regeneration
by Xuemiao Liu & Mingze Du & Weiguo Zhang & Kang Tian & Fuzhen Yuan & Xing Wang
- 1-25 Centralized brain networks controlling antennal grooming coordination
by Pembe Gizem Özdil & Jonathan Arreguit & Clara Scherrer & Femke Hurtak & Auke Ijspeert & Pavan Ramdya
- 1-25 Archaeal and eukaryotic MCM rings sequentially melt DNA for replication initiation
by Sanaz Rasouli & Alexander Myasnikov & Eric J. Enemark
- 1-25 BromoCatch: a self-labelling tag platform for protein modification and live cell imaging
by Maria Rodriguez-Rios & Conner Craigon & Mark A. Nakasone & Gajanan Sathe & Adam G. Bond & Mark Dorward & Anthony K. Edmonds & Mark C. Norley & Robert E. Arnold & Paul M. Wood & Stephen J. Reynolds & Joel O. Cresser-Brown & Graham P. Marsh & Hannah J. Maple & Alessio Ciulli
- 1-25 Chronic stress drives oligoasthenozoospermia via gut microbiota-vitamin-Sting1/Slc9c2 axis
by Jia-Chen Zheng & Zi-Run Jin & Bo-Heng Liu & Yue Tian & Jia-Xing Li & Jie Cai & Hui Jiang & Guo-Gang Xing
- 1-25 CAMPER: mechanistic artificial intelligence for designing peptides that target MRSA persisters
by Fadi Shehadeh & Biswajit Mishra & Raquel Ferrer-Espada & Anindya Basu & LewisOscar Felix & Charilaos Dellis & Narchonai Ganesan & Liyang Zhang & Andrew T. Martens & Youlian Goulev & Michael B. Sherman & Johan Paulsson & Mandar T. Naik & Paul P. Sotiriadis & Eleftherios Mylonakis
- 1-25 A combinatorial domain screening platform reveals epigenetic effector interactions for transcriptional perturbation
by Hyungseok C. Moon & Michael H. Herschl & Alessandra Sclip & Vincent Q. Tran & April Pawluk & Silvana Konermann & Patrick D. Hsu
- 1-25 Elevated temperature fatally disrupts nuclear divisions in the early Drosophila embryo
by Girish Kale & Pratika Agarwal & J. Jaime Diaz-Larrosa & Steffen Lemke
- 1-25 Active inference as a model of collision avoidance behavior in human drivers
by Julian F. Schumann & Johan Engström & Leif Johnson & Matthew O’Kelly & Joao Messias & Jens Kober & Arkady Zgonnikov
- 1-25 Fibronectin-induced overactivation of αVβ3-PI3K-PIP3-PDK1-ILK signaling drives aortic disease in Marfan syndrome
by Iván Alarcón-Ruiz & María Jesús Ruiz-Rodríguez & Sara Martínez-Martínez & Marta Toral & Noelia Martín-Bermejo & Sergio Mateos-García & Teresa Gil-Ruiz & Elías Herrero-Galán & María José Méndez-Olivares & Dolores López-Maderuelo & Carolina Gutiérrez-Martínez & Cristina Clemente & Alejandro Clemente-Manteca & Alberto H-Alcántara & Andrea Guala & Arturo Evangelista & Gisela Teixido-Tura & Diego Rodríguez-Puyol & Juan Francisco Nistal & Jorge Alegre-Cebollada & Jesús Vázquez & Juan Duarte & Juan Miguel Redondo & Miguel R. Campanero
- 1-25 Cholesterol-lowering effects of oats induced by microbially produced phenolic metabolites in metabolic syndrome: a randomized controlled trial
by Linda Klümpen & Aakash Mantri & Maren Philipps & Waldemar Seel & Laura Schlautmann & Mohamed H. Yaghmour & Verena Wiemann & Birgit Stoffel-Wagner & Martin Coenen & Leonie Weinhold & Jan Hasenauer & Thomas Fließwasser & Sven Burgdorf & Christoph Thiele & Peter Stehle & Marie-Christine Simon
- 1-25 Lactate derived from macrophages drives skin dermal fibroblasts phenotypic remodeling via MCT1-primed histone H3 lysine 23 lactylation in hypertrophic scar
by Yixuan Yuan & Yujie Xiao & Jie Zou & Liang Luo & Mengyang Li & Kuo Shen & Lai Wei & Yihao Zhang & Peng Wang & Yan Chen & Shixuan Zhuo & Hao Zhang & Shijie Song & Yanhui Jia & Kejia Wang & Shiqing Jiang & Hao Guan & Dahai Hu
- 1-26 Modular small RNA drives the emergence of virulence traits and environmental trade-offs in Vibrio cholerae
by Deepak Balasubramanian & Qinqin Pu & Cole Crist & Salvador Almagro-Moreno
- 1-26 Stress granule phase separation in stress-responsive cytosolic extract-in-oil droplets
by Aline Lieber & Oskar Staufer & Zhaozhi Sun & Ulrike Engel & Charlotte Flory & Nathan Mikhaylenko & Kevin Jahnke & Katja Kopp & Philipp Klein & Sarah Hofmann & Oliver T. Fackler & Pavel Ivanov & Ilia Platzman & Pietro Scaturro & Joachim P. Spatz & Alessia Ruggieri
- 1-26 Phylogenomic profile of exon-intron organization across angiosperms, their relationships with protein domains, and functional implications
by Taikui Zhang & Lin Zhang & Hong Ma & Jun Wang
- 1-26 Extensive variation between chromosomes of North American and European hop
by Sandip Mallikarjun Kale & Heidrun Gundlach & Oliver Gericke & Nadia Kamal & Aldo Almeida & Nicholi Pitra & Nicholas Price & Georg Haberer & Thomas Lux & Flavia Krsticevic & Oliver Kemp & Louise de Bang & Axel Himmelbach & Sudharsan Padmarasu & Mark-Timothy Rabanus-Wallace & Lucie Horáková & Václav Bačovský & Kasper Nielsen & Nanna Bjarnholt & Nikola Micic & Isabella Kruse-Andersen & Birger Lindberg Møller & Christian Janfelt & Birgitte Skadhauge & Paul D. Matthews & Klaus F. X. Mayer & Nils Stein & Martin Mascher & Manuel Spannagl & Alexander Feiner & Ilka Braumann
- 1-26 Mutant ribosomal protein RPS15 drives B cell malignancy through oxidative stress and genomic instability
by Catherine Gutierrez & Marwan Kwok & Neil Ruthen & Peyton Waddicor & Christina Curran & Tamara Ouspenskaia & Doris Fu & Brendan Smalec & Samantha Sedor & Binyamin A. Knisbacher & Anat Biran & Adi Nagler & Filip Garbicz & Tomasz Sewastianik & Johany Penailillo & Fabienne Lucas & Shanye Yin & Aviv Liani & Sarah Chen & Gregory Lazarian & Elizabeth Witten & Nathan Dangle & Ella L. Brunsting & Mei Zheng & Emma S. Lin & Madison J. Lee & Blake Wells & Lucas Pomerance & María Hernández-Sánchez & Shuqiang Li & Ziao Lin & Aziz Al’Khafaji & Lili Wang & Sudhir Thakurela & Kenneth J. Livak & Donna Neuberg & Florence Cymbalista & Gad Getz & Aviv Regev & Stirling Churchman & Elisa ten Hacken & Ruben Carrasco & Sichen Shao & Catherine J. Wu
- 1-26 Ultra-precision deconvolution of spatial transcriptomics decodes immune heterogeneity and fate-defining programs in tissues
by Yin Xu & Zurui Huang & Yawei Zhang & Minghui Gong & Zhenghang Wang & Peijin Guo & Feifan Zhang & Jing Yang & Guanghao Liang & Lihui Dong & Renbao Chang & Yu Xia & Haochen Ni & Wenxuan Gong & Boyuan Mei & Yuan Gao & Zhaoqi Liu & Lin Shen & Jian Li & Meng Michelle Xu & Dali Han
- 1-26 Homoharringtonine exhibits senotherapeutic activity that mitigates diet- and age-associated obesity and insulin resistance and extends lifespan in mice
by Eok-Cheon Kim & Han-Byul Jung & Yu-kyoung Park & Youlim Son & Hye-Na Cha & Yash Patel & Ju Hee Lee & Minah Choi & Soyoung Park & Il-Kug Kim & Lauren Pickel & Seungju Lee & Yuna Ha & Min-Gyeong Shin & Qiwei Zhang & Jielin Yang & Bruno Rodrigues de Oliveira & Nathaniel Vo & Annie Yew & Jacques Togo & Kafi N. Ealey & Su-Ryun Jung & Sunjin Moon & Hye-Jin Yoon & Jee-Young Lee & Hoon-Ki Sung & Jae-Ryong Kim & So-Young Park
- 1-26 Lithium exposure causes ferroptosis to induce unexplained miscarriage through non-canonical MBOAT1 pathway
by Sun Yi & Huang Wen Xin & Qigang Fan & Xiaoping Yue & Yanbing Lin & Xueyu Chen & Jun Xie & Peize Li & Shuaishuai Xing & Yang Chen & Qiong Lei & Manli Wang & Guo Geng & Zhao De peng & Zhang Hui dong
- 1-26 CDK2 inhibitor BLU-222 synergizes with CDK4/6 inhibitors in drug resistant breast cancers through p21/p27 induction
by Linjie Luo & Yan Wang & Tuyen Bui & Xiaoting Jiang & Mei-Kuang Chen & Xiayu Rao & Sepideh Mohammadhosseinpour & Mi Li & Serena Kim & Rachel Y. Kim & Saba Kamaliasl & Carmen W. Ulizio & Spyros Tsavachidis & Juliana Navarro-Yepes & Nicole M. Kettner & Hannah Wingate & Funda Meric-Bernstam & Kelly K. Hunt & Jing Wang & Kerrie Faia & Khandan Keyomarsi
- 1-26 Targeting chaperone-mediated autophagy inhibits properties of glioblastoma stem cells and restores anti-tumor immunity
by Yonghua Li & Min Sheng & Weijie Li & Simin Liu & Botao Wang & Bing Liu & Mei Luo & Xiao Zhou & Qiaoxi Xia & Shihong Hong & Ziyuan Zheng & Shi-Yuan Cheng & Xiaobing Jiang & Junjun Li & Tianzhi Huang
- 1-26 Pan-RAF inhibitor exarafenib targets BRAF class II/III NSCLC and reveals ARAF-KSR1 resistance and combination strategies
by Tadashi Manabe & Hannah C. Bergo & Qingtian Li & Tim Sen Wang & Paul Severson & Nichol Miller & Catherine Lee & Elifnur Yay Donderici & Nicole Zhang & Wei Wu & Yu-Ting Chou & Daniel L. Kerr & Paul Allegakoen & Kathryn B. Grandinetti & Liliana Soroceanu & Robert J. Pelham & Eric S. Martin & Eric A. Murphy & Vishesh Khanna & Joel W. Neal & Christopher T. Chen & Shumei Kato & Richard Williams & Trever G. Bivona
- 1-26 Reducing methylation of histone 3.3 lysine 4 in the medial ganglionic eminence and hypothalamus recapitulates neurodevelopmental disorder phenotypes
by Jianing Li & Anthony F. Tanzillo & Giusy Pizzirusso & Adam Caccavano & Ramesh Chittajallu & Mira Sohn & Daniel Abebe & Yajun Zhang & Kenneth A. Pelkey & Ryan K. Dale & Chris J. McBain & Timothy J. Petros
- 1-26 Discovery of NIRF theranostic probes targeting amyloid-β and cholinesterases in Alzheimer’s disease models
by Himanshu Rai & Rishabh Singh & Gauri Shankar & Sanskriti Rai & Prabhat Kumar & Aishwarya S. Nilakhe & Neha Singh & Poonam Bhadoria & Gourav Singh & Venkatnarayan Ramanathan & Sarika Gupta & Sairam Krishnamurthy & Saripella Srikrishna & Saroj Kumar & Gyan Modi
- 1-26 Native-like soluble E1E2 glycoprotein heterodimers on self-assembling protein nanoparticles for hepatitis C virus vaccine design
by Linling He & Yi-Zong Lee & Yi-Nan Zhang & Maddy L. Newby & Benjamin M. Janus & Fabrizio G. Gonzalez & Garrett Ward & Connor DesRoberts & Shr-Hau Hung & Erick Giang & Joel D. Allen & Liudmila Kulakova & Eric A. Toth & Thomas R. Fuerst & Mansun Law & Gilad Ofek & Max Crispin & Jiang Zhu
- 1-26 CK2 inhibition suppresses glial inflammation in models of neuroinflammation and neurodegeneration
by Ioana I. N. Da Silva & Desiree Ramirez & Sarah L. Parylak & Leslie A. Wallace & James K. Tucker & Joel M. Erberich & Rutvi Katariya & Aidan H. McDonald & Iryna S. Gallina & Ariana L. Tucker & Jillybeth Burgado & Baptiste N. Jaeger & Jerika J. Barron & Joshua M. Pratt & Monique Pena & Vipula Racha & Christina K. Lim & Sarah Fernandes & Simone Benassi & Lynne Randolph-Moore & Krishna C. Vadodaria & Maria C. Marchetto & Nicola J. Allen & Fred H. Gage
- 1-26 A proteogenomic atlas of 1032 brain metastases identifies molecular subtypes, immune landscapes, and therapeutic vulnerabilities
by Zhenyu Yang & Shiyou Wei & Hao Duan & Xiuqi Wang & Dainan Zhang & Karrie Mei-Yee Kiang & Yulan Deng & Yuanzhong Yang & Yin Ku & Wanming Hu & Chaowei Zou & Meiqin Tang & Yu Jiang & Yu Liu & Hongbin Lan & Zexin Chen & Gilberto Ka-Kit Leung & Wang Jia & Yonggao Mou & Lunxu Liu & Gao Zhang
- 1-27 Beta cell-derived cholecystokinin drives obesity-associated pancreatic adenocarcinoma development
by Cathy C. Garcia & Aarthi Venkat & Daniel C. McQuaid & Sherry S. Agabiti & Alexander Tong & Boby Mathew & Rebecca L. Cardone & Rebecca Starble & Christian F. Ruiz & Christy Zheng & Akin Sogunro & Jeremy B. Jacox & Ken H. Loh & Richard G. Kibbey & Smita Krishnaswamy & Mandar Deepak Muzumdar
- 1-27 Printing technologies for monitoring crop health
by David Panáček & Vojtěch Kupka & Martin-Alex Nalepa & Ivan Dědek & Ruslan Álvarez-Diduk & Selin Olenik & Jose Flauzino & Jan Zdražil & Petr Jakubec & Lukáš Zdražil & Lukáš Spíchal & Keval K. Sonigara & Radek Zbořil & Martin Pumera & Arben Merkoçi & Joseph Wang & Nuria De Diego & Firat Güder & Michal Otyepka
- 1-27 Bridging sequence-structure motifs and genetic variants for genome-wide dynamic RNA-protein interaction profiling
by Yubo Wang & Haoran Zhu & Gaoyang Hao & Yanchi Su & Zhuohan Yu & Yuning Yang & Fuzhou Wang & Xingjian Chen & Ka-chun Wong & Xiangtao Li
- 1-27 Spatial transcriptomics uncovers vasculature-centered cellular interactions driving Japanese encephalitis progression in a mouse model
by Zhihua Ou & Zhaoyang Wang & Qi Chen & Peidi Ren & Xiuju He & Yan Liang & Ying’an Liang & Jiaxuan Wang & Sha Liao & Dexin Wang & Jie Zhao & Oujia Zhang & Zhenyu Peng & Jianxin Su & Wangsheng Li & Guohai Hu & Ao Chen & Ziqing Deng & Xin Jin & Xun Xu & Junhua Li & Gong Cheng
- 1-27 Escherichia coli promotes colorectal cancer metastasis by maintaining enhancer-promoter loops through releasing neutrophil extracellular traps
by Banglun Pan & Yuxin Yao & Zhu Zhang & Dongjie Ye & Hao Wu & Xinyu Zhang & Xiaoqian Wang & Nanhong Tang
- 1-27 γδ T cell-stromal networks modulate matrix composition and vascularity in foreign body response
by Anna Ruta & Kavita Krishnan & JiWon Woo & Joscelyn C. Mejías & Elise F. Gray-Gaillard & David R. Maestas Jr. & Helen Hieu Nguyen & Alexandra N. Rindone & Christopher Cherry & Michael Patatanian & Frank Haoning Yu & Brenda Yang & Connor Amelung & Christina D. King & Birgit Schilling & Sharon Gerecht & Elana J. Fertig & Locke Davenport Huyer & Drew M. Pardoll & Jennifer H. Elisseeff
- 1-27 Gmppb-mutant mice exhibit dystroglycanopathy symptoms that are rescued with GSK3β inhibition or AAV-mediated GMPPB gene replacement
by Ziwei Fu & Tongchao Wang & Chenyang Zhang & Tianyu Qi & Yanyan Chen & Ju Yang & Hua Yang & Bing Yan & Baoming Gong & Weiqiao Lu & Sushan Luo & Ying Liu & Lei Sun & Hao Jiang & Bo Chen & Zhao Zhang & Xiuping Liu & Yuxiang Wang
- 1-27 Mechanisms of PfDNMT2 inhibition and PfATP6-mediated resistance to the antimalarial candidate SC83288 in Plasmodium falciparum
by Cecilia P. Sanchez & Maëlle Duffey & Romina V. Celada & Michal Kucharski & Marie Hoarau & Thanaya Saeyang & Sumalee Kamchonwongpaisan & Farzin Sohraby & Svenja de Buhr & Ariane Nunes Alves & Amuza Byaruhanga Lucky & Jun Miao & Clement Regnault & Jerzy M. Dziekan & Zbynek Bozdech & Michael P. Barrett & Michael Lanzer
- 1-27 Cross-species insights into placental evolution and diseases at the single-cell resolution
by Guanghui Tan & Ao Zhang & Xuesha Cao & Jingyu Yang & Youjie Cui & Fei Wang & Tao Shi & Hengkuan Li & Haoping Wang & Huiquan Shan & Jilong Ren & Yaqi Zhou & Menghan Wang & Funong Luo & Xi Guo & Wuqiang Huo & Yingran Liu & Zhannur Niyazbekova & Xihong Wang & Zhenyu Xiao & Yi Zheng & Yu Jiang
- 1-27 Activation of IRF3 in cardiomyocytes impairs mitochondrial oxidative function through PGC-1α inhibition and drives heart failure
by Manju Kumari & Ioannis Evangelakos & Anushka Deshpande & Kirstie A. De Jong & Nesrin Schmiedel & Nicolàs Palacio-Escat & Adriano de Britto Chaves-Filho & Roberto Carlos Frias-Soler & Glynis Klinke & Hyun Cheol Roh & Luisa Lange & Michael Berlin & Marceline M. Fuh & Jakob Johannes Buss & Tian Tian & Carolin Lerchenmüller & Marc Freichel & Almut Schulze & Viacheslav O. Nikolaev & Thomas Eschenhagen & Evan D. Rosen & Ludger Scheja & Ashraf Yusuf Rangrez & Joerg Heeren & Norbert Frey
- 1-27 Multiomics immune profiling of a patient-relevant orthotopic lung cancer model using SEPARATE-Seq
by Pauline M. R. Bardet & Lize Allonsius & Eva Hadadi & Daliya Kancheva & Morgane Paque & Sarka Vosahlikova & Aarushi A. Caro & Anouk Van Audenhove & Ayla Debraekeleer & Ria Roelandt & Kevin Verstaen & Michal Hensler & Delphine Hoton & Gisèle Mateu Cabrera & Louis Boon & Arnaud Blomme & Sofie Deschoemaeker & Geert Raes & Elly Marcq & Ahmed E. I. Hamouda & Jan P. Böttcher & Jitka Fucikova & Pierre Close & Frank Aboubakar Nana & Damya Laoui
- 1-27 Cartilage targeting hydrogel nanoplatform degrades BRD4 to alleviate osteoarthritis via Nav1.7 axis
by Qirui Zhao & Tongtong Xu & Zuchao Du & Xiaoqing Lu & Yan Zhang & Linjia Peng & Zixuan Gao & Weicheng Wang & Binyu Zhu & Zhigang Liu & Guangjie Yang & Hui Zhao & Zhiming Song & Qiankun Lou & Jiaming Li & Zhiguang Ren & Zhe Yu & Wei Wang & Yanlei Liu & Hui Liang & Jesus M. de la Fuente & Daxiang Cui
- 1-27 Bifidobacterium longum and prebiotic interventions restore early-life high-fat/high-sugar diet-induced alterations in feeding behavior in adult mice
by Cristina Cuesta-Marti & Eduardo Ponce-España & Friederike Uhlig & Iris Stoltenborg & Luiza A. Wasiewska & Lamiah Kareem & Dara Hedayatpour & Loreto Olavarría-Ramírez & Cristina Rosell-Cardona & Thomaz. F. S. Bastiaanssen & Gabriel. S. S. Tofani & Benjamin Valderrama & Klara Vlckova & Suzanne L. Dickson & Aonghus Lavelle & Catherine Stanton & R. Paul Ross & John F. Cryan & Timothy G. Dinan & Gerard Clarke & Siobhain M. O’Mahony & Harriët Schellekens
- 1-27 A multifaceted model of Entamoeba histolytica KERP2 regulating gene expression and host cell responses
by Ruofan Peng & Herbert J. Santos & Tomoyoshi Nozaki
- 1-27 Reprogramming of bacterial virulence by lysine acetylation
by Ole Schmöker & Britta Girbardt & Sabrina Schulze & Gottfried J. Palm & Leona Berndt & Jens Hoppen & Nilüfer Kara & Xenia Schöps & Ruba Al-Abdulla & Klara Garz & Heike Junker & Sophie Wolfgramm & Leif Steil & Christian Hentschker & Katrin Schoknecht & Lea-Maria Mayer & Leonie Speth & Vanessa Lachmayer & Mark Dörr & Stefan Kemnitz & Stefan Müller & Jan-Wilm Lackmann & Marcus Krüger & Kay Hofmann & Uwe T. Bornscheuer & Uwe Völker & Elke Krüger & Vera Kozjak-Pavlovic & Michael Lammers
- 1-28 Injectable hydrogels for osteomyelitis treatment induce metabolic reprogramming for protection against reinfection
by Haoyi Chen & Li Wei & Qiang Yu & Chenxi Wang & Huizhen Fan & Ming Li & Ruonan Dong & Yingying Ma & Jiahao Jiang & Lianfu Deng & Mei X. Wu & Min Lu
- 1-28 The role of low-complexity repeats in RNA–RNA interactions and a deep learning framework for duplex prediction
by Adriano Setti & Giorgio Bini & Flaminia Pellegrini & Valentino Maiorca & Gabriele Proietti & Dimitrios-Miltiadis Vrachnos & Angelo D’Angelo & Alexandros Armaos & Julie Martone & Michele Monti & Giancarlo Ruocco & Emanuele Rodolà & Irene Bozzoni & Alessio Colantoni & Gian Gaetano Tartaglia
- 1-28 Segmented filamentous bacteria are worldwide human gut commensals
by Shashi Kiran & Ana Raquel Cruz & Alice Daniau & Bing Ma & Martial Marbouty & Juliana Pipoli Da Fonseca & Agnès Legrand & Lyam Baudry & Thomas Cokelaer & Matthieu Bensussan & Maryse Moya-Nilges & Julian Garneau & Marc Monot & John B. Ochieng & Martin Antonio & Boubou Tamboura & Willem M. de Vos & Anne Salonen & Jahangir Hossain & Richard Omore & Samba O. Sow & Philippe J. Sansonetti & Jacques Ravel & Nadine Cerf-Bensussan & Pamela Schnupf
- 1-28 Ribosomal modifications are associated with mesenchymal fate selection in the neural crest lineage
by Irina Poverennaya & Aliia Murtazina & Lei Li & Lorena Maili & Lukas Sourada & Luis Fernando Montano-Gutierrez & Rozalina Galimullina & Tobias Steinschaden & Marketa Kaiser & Tomas Zikmund & Adna Goralija & Teng Gao & Aurore Attina & Ornella Clara & Christoph Bartenhagen & Alek Erickson & Yaakov Gershtein & Shiyuan Chen & Kristyna Polaskova & Jaroslav Sterba & Bettina Semasch & Emma R. Anderson & Varsha Prakash & Theresa Vincent & Maria Arceo & Per Kogner & Susanne Schlisio & Peter V. Kharchenko & Alexandre David & Jozef Kaiser & Matthias Fischer & Jan Skoda & Paul A. Trainor & Andrei S. Chagin & Igor Adameyko
- 1-29 Interpretable modality-aware mapping of gene regulation in single-cell multiomics with scMAGCA
by Yunhe Wang & Zeming Zhou & Wei Liu & Peiru Zhang & Yue Cheng & Yanchi Su & Fuzhou Wang & Ka-Chun Wong & Xiangtao Li
- 1-29 Ground squirrel coprolites preserve complex archives of ancient environmental DNA over 700,000 years
by Tyler J. Murchie & Scott L. Cocker & Sina Baleka & Nicola Alexandra Vogel & Libby Natola & Emil Karpinski & Diana Tirlea & McIntyre A. Barrera & Danielle M. Grant & Evan Morien & George S. Long & Linda Y. Rutledge & Grant D. Zazula & Britta J. Jensen & Duane G. Froese & Hendrik N. Poinar
- 1-29 Tumour-associated high endothelial venules drive portal-specific immune evasion in lymph nodes via ALOX12
by Qidong Xia & Jiayao Pan & Xiaoqi Weng & Shunrong Li & Jiaqian Li & Shijian Song & Jiang Li & Boxuan Zhou & Xinwei Liu & Dong-Ming Kuang & Nu Zhang & Jin Jin & Jinting Liu & Zhen Lin & Shubin Yu & Qionglan Tang & Lijuan Bian & Yunjie Zeng & Yu Shi & Yiqing Zheng & Jian-You Liao & Shouping Xu & Shicheng Su
- 1-30 Neuregulin-1 facilitates myelin regeneration through microglia-mediated mechanisms in a mouse model of chronic demyelination
by Seyyed Mohyeddin Ziaee & Shiva Nemati & Hardeep Kataria & Elisabet Jakova & Seyed Mojtaba Hosseini & Pejman Ghelich & Graham McLeod & Ali Tamayol & V. Wee Yong & Soheila Karimi-Abdolrezaee
- 1-30 Robust characterization and interpretation of rare pathogenic cell populations from spatial omics using GARDEN
by Xinming Zhang & Zhuohan Yu & Gaoyang Hao & Qi Yao & Yanmei Hu & Fuzhou Wang & Xingjian Chen & Linjing Liu & Ka-Chun Wong & Xiangtao Li
- 1-30 Bionic Janus hydrogel drives infected Achilles tendon regeneration via mechano-immune spatiotemporal steering
by Jie Li & Zishuo Wang & Wenjing Yang & Yuchen Zhang & Yanjun Wang & Xuhui Wang & Hongrui Wang & Yang Xie & Shuogui Xu & Yan Shang & Chunyu Xue & Yuntong Zhang & Shuo Fang
- 1-30 Neuropeptide SP protects against colitis and linked anxiety-like behavior through the putative roles of gut microbiota and metabolite inositol
by Jing Lan & Jiaqi Wang & Sijuan Huang & Chenyu Li & Ziteng Deng & Zhihui Hao & Yunfei Ma
- 1-30 Developments and challenges in hit progression within fragment-based drug discovery
by Harold Grosjean & Philip C. Biggin
- 1-31 Variants in the proteasome regulator PSMF1 cause a phenotypic spectrum from parkinsonism to perinatal lethality
by Francesca Magrinelli & Christelle Tesson & Plamena R. Angelova & Jose A. Rodriguez & Annarita Scardamaglia & Benjamin O’Callaghan & Simon A. Lowe & Ainara Salazar-Villacorta & Brian Hon-Yin Chung & Matthew Jaconelli & Barbara Vona & Noemi Esteras & Angela Mammana & Junko Shimazu & Anna Ka-Yee Kwong & Thomas Courtin & Shahryar Alavi & Reza Maroofian & Raja Nirujogi & Mariasavina Severino & Edoardo Monfrini & Clarissa Rocca & Patrick A. Lewis & Stephanie Efthymiou & Rebecca Buchert & Linda Sofan & Pawel Lis & Chloé Pinon & Guido J. Breedveld & Martin Man-Chun Chui & David Murphy & Vanessa Pitz & Mary B. Makarious & Simone Baiardi & Marina Volin & Marlene Cassar & Bassem A. Hassan & Sana Iftikhar & Peter Bauer & Michele Tinazzi & Marina Svetel & Bedia Samanci & Haşmet A. Hanağası & Basar Bilgiç & Francesco Cavallieri & Mario Santangelo & José A. Obeso & Monica M. Kurtis & Guillaume Cogan & Güneş Kiziltan & Tuğçe Gül-Demirkale & Hülya Tireli & Gülbün A. Yüksel & Gül Yalçın-Cakmakli & Bülent Elibol & Nina Barišić & Earny Wei-Sen Ng & Sze-Shing Fan & Tova Hershkovitz & Karin Weiss & Javeria Raza Alvi & Tipu Sultan & Issam Azmi Alkhawaja & Tawfiq Froukh & Hadeel Abdollah E. Alrukban & Muhammad Nadeem Anjum & Anjum Saeed & Huma Arshad Cheema & Christine Fauth & Ulrich A. Schatz & Thomas Zöggeler & Michael Zech & Karen Stals & Vinod Varghese & Sonia Gandhi & Cornelis Blauwendraat & John A. Hardy & Alessio Di Fonzo & Vincenzo Bonifati & Tobias B. Haack & Aida M. Bertoli-Avella & Suzanne Lesage & Ayşe Nazlı Başak & Robert Steinfeld & Piero Parchi & James E. C. Jepson & Dario R. Alessi & PSMF1 Study Group & Alexis Brice & Hermann Steller & Andrey Y. Abramov & Kailash P. Bhatia & Henry Houlden
- 1-32 NEDAMSS syndrome-related truncating and missense mutations are associated with aberrant liquid-liquid phase separation of IRF2BPL
by Marco Dell’Oca & Stefania Boggio Bozzo & Serena Vaglietti & Chiara Marchetti & Chiara Di Luca & Pietro Munarin & Michael Nicoli & Rossella Indellicato & Davide Ravanelli & Giorgia Falanga & Angelo Iannielli & Mirko Luoni & Alessia Loffreda & Valeria Berno & Paolo Bianchini & Sarah Sertic & Antonio Conforti & Shima Rashidiani & Eleonora Aimaretti & Massimo Collino & Ilaria Cecere & Angelo Gallo & Federica Santoro & Diego Brancaccio & Samuele Rosso & Giovanna Di Nardo & Raffaele Pertusio & Federico Cesano & Francisco J. Monje Quiroga & Mirella Ghirardi & Silvestro Roatta & Luca Colnaghi & Ferdinando Fiumara
- 1-34 Systematic review and meta-analysis of stroke blood biomarker data highlights need for more translational research methods
by Christine G. Smothers & Shivam A. Gandhi & Julia H. Chang & Sadia M. Tahir & Jarrett Kelley & Emily Wang & Kareem Fareed & Hannah Mack & Cindy Dong & Madaline Witort & Bethany L. Armentrout & Darynaisha Crawford & Jing Wang & Kara Williams & Zea Bud & Christine Horvat-Davey & Chris Winkelman & Sarah R. Martha & Jon W. Schrock & Agnieszka A. Ardelt & Grant C. O’Connell
December 2025, Volume 16, Issue 1
Printed from https://ideas.repec.org/s/nat/natcom18.html