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Content
December 2026, Volume 17, Issue 1
- 1-21 Sarcopenia promotes tumorigenesis by disrupting NOTCH-SDC2-regulated biogenesis of muscle-derived extracellular vesicles
by Kah Yong Goh & Wen Xing Lee & Qian Gou & Sze Mun Choy & Shi Chee Ong & Priya D. Gopal Krishnan & Huaxin Wang & Lewin Raymarc Roldan Turqueza & Qian Hui Tan & Kenon Chua & Shang Li & Jun Nishiyama & Nathan Harmston & Hong-Wen Tang
- 1-21 Combined targeted and epigenetic-based therapy enhances antitumor immunity by stabilizing GATA6-dependent MHCI expression in pancreatic ductal adenocarcinoma
by JuanFei Peng & JiaJin Yang & Georgia Antonopoulou & Rui Fang & Bikash Adhikari & Markus Vogt & Elmar Wolf & Chong Sun & Shangce Du & Laura Godfrey & Aayush Gupta & Marija Trajkovic-Arsic & Nicole Teichmann & Barbara T. Grünwald & Niklas Krebs & Katja Steiger & Carolin Mogler & Kristina Althoff & Xin Wang & Giovanni Giglio & Sven-Thorsten Liffers & Konstantinos Savvatakis & Rickmer Braren & Rita T. Lawlor & Aldo Scarpa & Diana Behrens & Karl S. Lang & Phyllis F. Cheung & Jens T. Siveke
- 1-21 Blockage of autophagy causes severe skeletal muscle disruption in a mouse model for myofibrillar myopathy 6
by Kerstin Filippi & Kathrin Graf-Riesen & Maithreyan Kuppusamy & Andreas Unger & Kenichi Kimura & Martin Matijass & Henrique Baeta & Magdalena Podlacha & Daniel Haertter & Alexei P. Kudin & Martin Wiemann & Grzegorz Węgrzyn & Cornelia Kornblum & Jens Reimann & Wolfgang A. Linke & Pitter F. Huesgen & Wolfram S. Kunz & Bernd K. Fleischmann & Michael Hesse
- 1-21 Glycerol 3-phosphate acyltransferase exacerbates α-synuclein-induced toxicity by increasing lipid peroxidation
by Mengda Ren & Grace G. Y. Lim & Willcyn Tang & Kah-Leong Lim
- 1-21 5’tRNA-derived fragments modulate β-cell homeostasis and islet macrophage activation in type 2 diabetes
by Cristina Cosentino & Rémy Klein & Véronique Menoud & Claudiane Guay & Elena Aiello & Stefano Auddino & Gianfranco Di Giuseppe & Gea Ciccarelli & Alessandra Galli & Francesco Alabiso & Eleonora Mangano & Flora Brozzi & Karim Bouzakri & Stefania D’Adamo & Silvia Cetrullo & Giuseppe Quero & Andrea Mari & Sergio Alfieri & Andrea Giaccari & Teresa Mezza & Francesco Dotta & Guido Sebastiani & Romano Regazzi
- 1-21 Counting cells can accurately predict small-molecule bioactivity benchmarks
by Srijit Seal & William Dee & Adit Shah & Natacha Cerisier & Andrew Zhang & Esteban Miglietta & Katherine Titterton & Ángel Alexander Cabrera & Daniil Boiko & Alex Beatson & Gregory Slabaugh & Olivier Taboureau & Jordi Carreras Puigvert & Shantanu Singh & Ola Spjuth & Andreas Bender & Anne E. Carpenter
- 1-21 Functional requirement for Dicer helicase arginine methylation in 26 G siRNA biogenesis and oocyte meiotic program
by Nick Newkirk & Shin-Yu Chen & Tokiko Furuta & Kenneth A. Trimmer & Leilei Shi & Sabrina Stratton & Hongyuan Li & Xiaodong Cheng & Mark T. Bedford & Swathi Arur
- 1-21 CAR-CD34 (+) hematopoietic stem/progenitor cells produced in vivo protect against thoracic aortic aneurysm and dissection
by Kaiwen Zhao & Yuzhen He & Renqi Yao & Shuangshuang Li & Lingxu Kong & Jinzhu Niu & Zan Zeng & Pengcheng Du & Hongqiao Zhu & Rong Zhao & Taiping Liang & Zaiping Jing & Jian Zhou
- 1-21 Endemism and regionalization patterns of squamate reptiles in Amazonia
by Marco Antônio Ribeiro-Júnior & Josué Anderson Rêgo Azevedo & Cristiano de Campos Nogueira & Silvana Amaral
- 1-21 Cancer cell-intrinsic inflammasome protein ASC links innate immunity with mitochondrial metabolism in driving pancreatic cancer
by Yu C. J. Chey & Bassam Kashgari & Louise McLeod & Georgette A. Radford & Linden J. Gearing & Ruby E. Dawson & Malvika Kharbanda & Joanne Lundy & Daniel Croagh & Charlotte Girard-Guyonvarc’h & Cem Gabay & Brooke A. Pereira & David Herrmann & Paul Timpson & John W. Finnie & Mohamed I. Saad & Dharmesh D. Bhuva & Bernardo S. Franklin & Florian I. Schmidt & Brendan J. Jenkins
- 1-21 Gut microbiome features associated with Bifidobacterium colonization predict personalized probiotic persistence patterns
by Sourav Goswami & Alisha Ansari & Chetan Sharaf & Paul W. O’Toole & Fergus Shanahan & Vineet Ahuja & Tarini Shankar Ghosh
- 1-21 Cyclophilin A stabilizes the capsid protein p72 to facilitate African swine fever virus replication
by Hui Kong & Liqin Yang & Zhenjiang Zhang & Ying Zhang & Linlin Liu & Wan Wang & Linfei Song & Yuanmao Zhu & Encheng Sun & Fang Li & Zhigao Bu & Xiangpeng Sheng & Dongming Zhao
- 1-21 HCMV infection disrupts barrier functions and promotes epithelial–mesenchymal transition in a cholangiocyte organoid model
by Zuodong Ye & Xinyan Hu & Syed Mushfiqur Rahaman & Yuelan Zheng & Xiaoman Zhang & Clara Sze Man Tang & Tsz Man Yau & Wang Ka Lee & Patrick Ho Yu Chung & Kenneth Kak Yuen Wong & Paul Kwong Hang Tam & Vincent Chi Hang Lui & Allen Ka Loon Cheung
- 1-21 DUSP26 protects against acute kidney injury by dephosphorylating p53 at serine 312
by Ying Fu & Yu Xiang & Yun Han & Juan Cai & Shaobin Duan & Anqun Chen & Zheng Dong
- 1-21 Spatial patterning of contractility by a self-organized mechanogen activity gradient underlies Drosophila gastrulation
by Gayatri Mundhe & Valentin Dunsing-Eichenauer & Jean-Marc Philippe & Élise Da Silva & Claudio Collinet & Thomas Lecuit
- 1-21 Systematic multi-omic deconvolution of the clinical heterogeneity of Down syndrome
by Micah G. Donovan & Srija Chillamcherla & Belinda A. Enriquez Estrada & Kayleigh R. Worek & Zenitha Sundararajan & Kyle W. Barstch & Kelly D. Sullivan & Matthew D. Galbraith & Angela L. Rachubinski & Joaquin M. Espinosa
- 1-21 Endothelial cannabinoid CB1 receptor deficiency reduces shear stress-induced arterial inflammation and lipid uptake
by Bingni Chen & Aishvaryaa Prabhu & Guo Li & Anna Kaltenbach & Yong Wang & George Shakir & Lucia Natarelli & Remco Megens & Yvonne Jansen & Srishti Ramanathan & Martina Geiger & Alexander Faussner & Michael Hristov & Daniel Richter & Xinyu Di & Mario van der Stelt & Vasiliki Triantafyllidou & Zhaolong Li & Nadja Sachs & Valentina Paloschi & Lars Maegdefessel & Susanna M. Hofmann & Martina Schifferer & Mikael Simons & Christian Weber & Donato Santovito & Stephan Herzig & Raquel Guillamat Prats & Sabine Steffens
- 1-21 Remodeling synaptic connections via engineered neuron-astrocyte interactions
by Shin Heun Kim & Woojin Won & Gyu Hyun Kim & Yeon Hee Kook & Seungkyu Son & Songhee Choi & Dong Yeop Kang & Mingu Gordon Park & Young-Jin Choi & Seong Su Won & Juhee Shin & Yong Jeong & Kea Joo Lee & C. Justin Lee & Sangkyu Lee
- 1-21 The mosaic memory of large language models
by Igor Shilov & Matthieu Meeus & Yves-Alexandre de Montjoye
- 1-21 A ketogenic diet enhances aerobic exercise adaptation and promotes muscle mitochondrial remodeling in hyperglycemic male mice
by Pattarawan Pattamaprapanont & Roberto C. Nava & Rea Grover & Mia Formato & Eileen M. Cooney & Ana Paula Pinto & Ana B. Alves-Wagner & Anamica Das & Yuntian Guan & Meghana Annambhotla & Saanvi Acharya & Donato A. Rivas & Sarah J. Lessard
- 1-21 Low-intensity focused ultrasound-activated piezoelectric gel bandage for diabetic wound repair and neuropathic pain relief
by Xiao Li & Lizhou Lin & Mingrui Zhu & Xiaolong Li & Jifeng Yu & Dan Lu & Shaoyue Li & Yuting Shen & Bing Xiong & Chongke Zhao & Boyang Zhou & Haohao Yin & Huixiong Xu & Xin Guan
- 1-21 Ultrasmall oral Saccharibacteria modulate gingival immunoactivation through type IV pili and TLR2-dependent endocytosis
by Deepak Chouhan & Alex S. Grossman & Kristopher A. Kerns & Kendall S. Stocke & Maya Kim & Pu-Ting Dong & Ajay Kumar & Lei Lei & Richard J. Lamont & Jeffrey S. McLean & Xuesong He & Batbileg Bor
- 1-21 A genus-wide interaction atlas across NS4B orthologues identifies a conserved role for UFMylation in orthoflavivirus replication
by Sreejith Rajasekharan & Viviana Andrea Barragan Torres & Yago Cortes Pinheiro Gomes & Lucas Wilken & Katharina Overhoff & Yen-Chia Lin & Shunmoogum A. Patten & Satoru Watanabe & Laurent Chatel-Chaix & Pietro Scaturro
- 1-21 Three parsimonious spatiotemporal patterns in cerebellum reveal individual traits in function and behavior
by Shuo Lv & Jinlong Li & Ruoqi Yang & Xinyu Wu & Zhiming Wang & Wenjing Zhu & Tan Gao & Jia-Hong Gao & Guoyuan Yang
- 1-21 Deviation in development of dorsal association tracts during preadolescence links to concurrent and future cognitive performance and transdiagnostic psychopathology
by Danni Wang & Christopher J. Hammond & Betty Jo Salmeron & Xiang Xiao & Laura Murray & Hong Gu & Tianye Zhai & Annika Quam & Justine Hill & Hieu Nguyen & Hanbing Lu & Amy Janes & Thomas J. Ross & Yihong Yang
- 1-21 Programmable multiscale energy release in synergistic energetic composites with three dimensional printed architectures
by Yongjin Chen & Hui Ren & Haoyue Xin & Xinzhou Wu & Qingjie Jiao
- 1-21 A comparative transcriptomic analysis of mouse demyelination models and multiple sclerosis lesions
by Erin L. Aboelnour & Veronica R. Vanoverbeke & Elizabeth A. Maupin & Madelyn M. Hatfield & Katrina L. Adams
- 1-21 Early life exposure to N-nitrosamine drives genotoxicity, mutagenesis, and tumorigenesis in DNA repair-deficient mice
by Lindsay B. Volk & Monét Norales & Callie Karjane & Joshua J. Corrigan & Alper J. Alcaraz & Lee J. Pribyl & Nicolette A. Bugher & Megan Blawas & Isabella Dulski & Einthavy Arunachalam & Nina Gubina & Emily Michelsen & Kannammai Pichappan & Natalya Yakimchuk & Matilda Swanson & Duanduan Ma & Stuart S. Levine & Desiree L. Plata & Robert G. Croy & Leona D. Samson & John M. Essigmann & Carole L. Yauk & Sebastian E. Carrasco & Bevin P. Engelward
- 1-21 Disruption of the SAGA CORE triggers collateral degradation of KAT2A
by Paul Batty & Hannah Beneder & Caroline Schätz & Gabriel Onea & Maciej Zaczek & Ana P. Kutschat & Miriam Abele & Sophie Müller & Giulio Superti-Furga & Georg E. Winter & Davide Seruggia
- 1-21 Binary mineral nanoparticles enable intravascular delivery of metal ions to tumors for metalloimmunotherapy
by Bao Loc Nguyen & Ngoc Duy Le & Thi Oanh Oanh Nguyen & Daehyeon Ahn & Basavaraj Rudragouda Patil & Beomsu Kim & Cao Dai Phung & Duc-Vinh Pham & Jung Min Lee & Jiwoo Hong & Jae-Hoon Chang & Sae Kwang Ku & Jeonghwan Kim & Jong Oh Kim
- 1-21 Functional variants at 1p36.23 confer risk of schizophrenia through modulating RERE
by Yixing Liu & Junyang Wang & Hong Yang & Yifan Li & Changgai Mu & Xinglun Dang & Xinran Chen & Danyang Li & Mingna Li & Jiewei Liu & Shiwu Li & Jinfeng Yang & Xi Chen & Chen Zhang & Jin Feng & Xiong-Jian Luo
- 1-21 Chlorella-derived extracellular vesicle-based nanogels suppress cGAS-STING for treatment of radiation-induced lung injury
by Huiqun Hu & Feng Lu & Wenting Zhang & Zengwen Zhang & Jiarong Cui & Xiaoyue Lei & Jingyan Xia & Feng Xu
- 1-21 Robust intensification of projected regional precipitation extremes over Africa
by Akintomide A. Akinsanola & Thierry N. Taguela & Vishal Bobde
- 1-21 α/Sulfonyl-γ-AApeptide foldamers mitigate Alzheimer’s disease pathology by stabilizing transient helical domains in Aβ
by Heng Liu & Firoz Akhter & Asma Akhter & Xue Zhao & Xudong Wang & Haiqiang Yang & Jianyu Chen & Xinyu Xia & Laurent Calcul & Yi He & Chuanhai Cao & Libin Ye & Donghui Zhu & Jianfeng Cai
- 1-21 Multi-lineage hepatic organoids reveal toxic exosome mediated indirect hepatotoxicity
by Lei Sun & Yuying Zhang & Yudi Niu & He Yang & Lyu Zhou & Xiaodong Jia & Yihan Chen & Zhiqiang Liu & Tiantian Wang & Kaini Liang & Dongdong Fan & Sida Ling & Zhen Zeng & Yanan Du
- 1-21 Self-assembling scaffolds epigenetically reactivate and electroactively guide neuronal regeneration to restore central neural circuits
by Shiqiang Tong & Shuai Ye & Fenfen Ma & Xiaoying Xie & Yinzhe Sun & Chuchu Ma & Tiantian Shi & Zheng Cheng & Chang Li & Weili Han & Laozhi Xie & Songlei Zhou & Jianing Gong & Chen Huang & Yukun Huang & Gan Jiang & Xiaolin Liu & Bing Li & Feng Zeng & Jingru Gong & Zhihua Wang & Xiaoling Gao & Qiyong Mei & Wei-Guang Li & Jun Chen
- 1-21 JAK inhibitors alleviate EGFR-inhibitor-induced diarrhea by protecting intestinal stem cells from adaptive-immune-exacerbated injury
by Yuan Cheng & Chenyue Xu & Dazhao Lv & Meng Tian & Haoyu Wang & Bingxue Yang & Leying Chen & Qing You & Shiyi Zhang
- 1-21 Janus nanomotors for topical treatment of radiation-induced dermatitis
by Wen Zhang & Wei Liu & Xiaoyu Zhao & Yuanfang Chen & Changfen Bi & Shuqin Li & Bingwen Zou & Luntao Liu & Saijun Fan
- 1-21 CXCR4 induces memory formation over exhaustion in CAR-T cells to achieve durable leukemia targeting
by Ari Itoh-Nakadai & Minggao Liang & Michiho Shindo & Chen Bibi & Mariko Tomizawa-Murasawa & Saera Fujiki & Akiko Kaneko & Emi Kanamaru & Mari Hashimoto & Hiroshi Kajita & Yoshinari Ando & Miki Kojima & Jonathan Moody & Makoto Iwasaki & Shinsuke Takagi & Ryo Nakagawa & Saumya Agrawal & Hanae Amitani-Iijima & Kaori Sato & Yuriko Sorimachi & Nahoko Suzuki & Takehiro Fukami & Kazuharu Hanada & Satoshi Morita & Kazushige Katsura & Takehisa Matsumoto & Maiko Kobayashi & Masahiko Kato & Yasuyuki Negishi & Mikako Shirouzu & Yuho Najima & Keiyo Takubo & Chung Chau Hon & Naoyuki Uchida & Shuichi Taniguchi & Yukihide Momozawa & Piero Carninci & Leonard D. Shultz & Yoriko Saito & Michiel de Hoon & Jay W. Shin & Fumihiko Ishikawa
- 1-21 Chamber-specific chromatin architecture guides functional interpretation of disease-associated Cis-regulatory elements in human cardiomyocytes
by S. Haydar & R. Bednarz & P. Laurette & I. Sobitov & N. Díaz i Pedrosa & P. Videm & T. Lueneburg & S. Kuß & H. Lahm & M. Dreßen & M. Krane & C. Schmidt & B. A. Grüning & N. Voigt & K. Streckfuss-Bömeke & R. Gilsbach
- 1-21 Biomimetic model of corticostriatal micro-assemblies discovers a neural code
by Anand Pathak & Scott L. Brincat & Haris Organtzidis & Helmut H. Strey & Sageanne Senneff & Evan G. Antzoulatos & Lilianne R. Mujica-Parodi & Earl K. Miller & Richard Granger
- 1-21 Tmem110 regulates the conformation of TRPML1 to maintain endolysosomal homeostasis and prevent mitochondrial DNA leakage and pathological self-DNA processing
by Zunyong Feng & Yuanbo Pan & Jing Zhou & Liuxi Chu & Qiang Li & Xuanbo Zhang & Ping Wu & Zhiliang Xu & Yanjiao Huang & Jianhua Zou & Xiaokun Li & Xiaoyuan Chen & Zhouguang Wang
- 1-21 Triple targeting of STING, TGF-β, and PD-L1 boosts CXCL16–CXCR6 signaling for potent antitumor response
by Ming Yi & Tianye Li & Yinhui Gu & Mengke Niu & Dixuan Xue & Shengtao Hu & Yuze Wu & Bin Zhao & Di Zhang & Yingkang Ma & Minjun Zhang & Jing Zhang & Yongxiang Yan & Pengfei Zhou & Xiaojun Zhang & Zhuxian Zhou & Qian Chu & Kongming Wu & Zhijun Dai
- 1-21 PD-1 blockade plus tyrosine kinase inhibitor remodels the tumor microenvironment in advanced renal cell carcinoma
by Liangyou Gu & Qi Zhang & Qiyang Liang & Cheng Peng & Yaohui Wang & Chenfeng Wang & Zhuoran Li & Yezhen Tan & Yanming Zhou & Qing Bi & Xiubin Li & Jin Luo & Qingbo Huang & Yan Huang & Xu Zhang & Xin Ma & Weimin Ci & Baojun Wang
- 1-21 A generic reference defined by consensus peaks for single-cell ATAC-seq data analysis
by Qiuchen Meng & Xinze Wu & Wenchang Chen & Yubo Zhao & Chen Li & Zheng Wei & Xiaocheng Zeng & Jiaqi Li & Xi Xi & Sijie Chen & Catherine Zhang & Shengquan Chen & Jiaqi Li & Xiaowo Wang & Rui Jiang & Lei Wei & Xuegong Zhang
- 1-21 Native chromatome profiling reveals hundreds of metabolic enzymes in the nucleus across tissues
by S. Kourtis & A. Gañez Zapater & CR Elbæk & A. Schmidt & R. Ghose & A. Coll Manzano & L. Espinar Calvo & M. Guirola & N. Pardo-Lorente & M. Garcia-Cao & M. Pfeiffer & S. Haynes & F. Fontaine & A. Müller & S. Sdelci
- 1-21 A multimodal approach for visualizing and identifying electrophysiological cell types in vivo
by Eric Kenji Lee & Asım E. Gül & Greggory Heller & Anna Lakunina & Han Yu & Andrew Shelton & Shawn Olsen & Nicholas A. Steinmetz & Cole Hurwitz & Santiago Jaramillo & Pawel F. Przytycki & Chandramouli Chandrasekaran
- 1-21 DIS3 mutations enhance AID-driven translocations during B-cell activation, promoting transformation to multiple myeloma
by Tomasz M. Kuliński & Olga Gewartowska & Mélanie Mahé & Karolina Kasztelan & Nina Durys & Anna Stroynowska-Czerwińska & Marta Jedynak-Slyvka & Ewelina P. Owczarek & Debadeep Chaudhury & Marcin Nowotny & Aleksandra Pękowska & Bertrand Séraphin & Andrzej Dziembowski
- 1-21 Loss-of-function variants in the CAPN1 activator CD99L2 cause X-linked spastic ataxia
by Benita Menden & Rana D. Incebacak Eltemur & German Demidov & Marc Sturm & Joohyun Park & Chrisovalantou Huridou & Florian Fath & Astrid Nümann & Alexander Baumann & Illja J. Diets & Claudia Dufke & Martin Regensburger & Maria Rönnefarth & Vera Wilke & Nienke van Os & Stefan Vielhaber & Tim W. Rattay & Zacharias Kohl & Susana Peralta & Priscila Pereira Sena & Melanie Kellner & Nadine Weissert & Andreas Traschütz & Lena Zeltner & Kai Boelmans & Natalie Deininger & Leon Schütz & Caspar Gross & Ana Beatriz Hinojosa Amaya & Katrin Raupach & Holger Hengel & Florian Harmuth & Jakob Admard & Ingrid Bader & Sarah Baumann & Friedemann Bender & Andrea Bevot & Almut Bischoff & Felix Boschann & Rebecca Buchert & Daniel Buchzik & Nicolas Casadei & Claudia B. Catarino & Isabell Cordts & Kirsten Cremer & Marion Doebler-Neumann & Nadja Ehmke & Miriam Elbracht & Ruth J. Falb & Thomas Feindt & Zofia Fleszar & Lea Gerstner & Dieter Gläser & Ute Grasshoff & Sarah Grosch & Kathrin Grundmann & Alexander Gutschalk & Manja Haaga & Stefanie Hayer & Ute Hehr & Yorck Hellenbroich & Wolfram Henn & Barbara Herr & Rebecca Herzog & Veronka Horber & Jonas Deppe & Nadja Kaiser & Christiane Kehrer & Martin Kehrer & Jan Kern & Christoph Keßler & Katharina Khuller & Hannah Klinkhammer & Urania Kotzaeridou & Peter Krawitz & Martina Kreiss & Hanna Küpper & Alice Kuster & Lucia Laugwitz & Anne Lesemann & Nadine Lichey & Tobias Linden & Boris Macek & Janine Magg & Elisabeth Mangold & Eva Manka & Iris Marquardt & Karl Mehnert & David Mengel & Susanne Morlot & Barbara Oehl-Jaschkowitz & Martje G. Pauly & Melanie Philipp & Florentine Radelfahr & Maren Rautenberg & Angelika Riess & Carsten Saft & Beate Schlotter-Weigel & Axel Schmidt & Eva M. C. Schwaibold & Veronika Spahlinger & Stephanie Spranger & Katharina Marie Steiner & Claudia Stendel & Andreas Thieme & Andreas Tzschach & Ana Velic & Sarah Wiethoff & Carlo Wilke & Stephan Züchner & Simone Zittel & Ralf A. Husain & Marcus Deschauer & Felix Distelmaier & Andreas Dufke & Holm Graessner & Bernhard Hemmer & Heike Jacobi & Thomas Klockgether & Thomas Klopstock & Xenia Kobeleva & Georg-Christoph Korenke & Alma Kuechler & Gregor Kuhlenbäumer & Ingo Kurth & Huu Phuc Nguyen & Gilbert Wunderlich & Kirsten E. Zeuner & Stephan Klebe & Michaela Auer-Grumbach & Michaela Butryn & Jürgen Winkler & Dagmar Timmann & Matthis Synofzik & Bart van de Warrenburg & Rebecca Schüle & Ludger Schöls & Stephan Ossowski & Olaf Riess & Jonasz J. Weber & Tobias B. Haack
- 1-21 Dynamic transcriptomic remodeling in grafted human neural progenitor cells uncovers mechanisms for vision preservation in a rat model of retinitis pigmentosa
by Saba Shahin & Shaughn Bell & Bin Lu & Somanshu Banerjee & Vivek Swarup & Hui Xu & Jason Chetsawang & Stephany Ramirez & Jorge S. Alfaro & Alexander Laperle & Soshana Svendsen & Clive N. Svendsen & Shaomei Wang
- 1-21 Endothelial FUNDC1 regulates metabolic reprogramming and the obesity-diabetes transition through the SIRT3/GATA2/endothelin-1 axis
by Jian Li & Dayong Li & Fujie Zhao & Yadong Wang & Hongmin Yao & Yin Wu & Junqing An & Zhixue Liu & Ye Ding & Ming-Hui Zou
- 1-21 Pyruvate metabolism enzyme Dlat induces mitochondria protein hyperacetylation to limit fatty acid oxidation in the HFpEF heart
by Ying Wang & Dong Guo & Jin’ao Zhu & Xue Yang & Chan Wu & Jing Geng & Qi Liang & Nan Sun & Xiaona Niu & Yue Liu & Yanjie Guo & Pan Chang & Yan Li & Lang Hu
- 1-21 Systems acclimation to osmotic stress in zygnematophyte cells
by Jaccoline M. S. Zegers & Lukas Pfeifer & Tatyana Darienko & Kerstin Schmitt & Craig A. Dorsch & Cäcilia F. Kunz & Gerhard H. Braus & Birgit Classen & Oliver Valerius & Jan de Vries
- 1-21 Phytic acid (InsP6) activates HDAC3 epigenetic axis to maintain intestinal barrier function
by Sujan Chatterjee & Zachary Sin & Nguyen Tran & Loretta Vierra & Anuj Shukla & Tam Tran & George Koshkaryan & Kevin Ritter & Xue Bessie Su & Saharat Jolak Ragsac & Seungman Park & Qian Liu & Richard Van & Katherine Huang & Kayci Huff-Hardy & Richard Rood & Anas Gremida & Martin Gregory & Chien-Huan Chen & Mira V. Han & Parakkal Deepak & Adolfo Saiardi & Henning J. Jessen & Prasun Guha
- 1-21 FGF7 promotes load-bearing tendon regeneration and suppresses fibrosis
by Ruifu Lin & Junchao Luo & Hong Zhang & Chunmei Fan & Yue Hu & Ruojin Yan & Zetao Wang & Yang Fei & Chenqi Tang & Tianxi Huang & Tianshun Fang & Weiliang Shen & Sunbin Ling & Hongwei Ouyang & Xiao Chen & Zi Yin
- 1-21 Interplay between T3SS effectors, ExoY activation, and cGMP signaling in Pseudomonas aeruginosa infection
by Vincent Deruelle & Gabrielle Dupuis & Dorothée Raoux-Barbot & Elysa Lim & Roberto Ponce-López & Magda Teixeira Nunes & Daniel Ladant & Louis Renault & Undine Mechold
- 1-21 Restoring early postnatal synaptic dysregulation rescues motor neuron degeneration in a mouse model of Spinal and Bulbar Muscular Atrophy
by Tomoki Hirunagi & Kentaro Sahashi & Madoka Iida & Kazunari Onodera & Satoshi Yokoi & Yosuke Ogura & Genki Tohnai & Kenji Sakakibara & Kentaro Maeda & C. Frank Bennett & Yohei Okada & Masahisa Katsuno
- 1-21 Anti-PD-1 plus anti-CTLA-4 blockade overcomes immune exclusion in NSCLC brain metastases by enhancing CD8+ T cell responses and promoting tertiary lymphoid structure formation
by Kazutaka Hosoya & Hiroaki Ozasa & Takahiro Tsuji & Masahiro Oi & Yusuke Shima & Keiichiro Suminaga & Kentaro Hashimoto & Hiroshi Yoshida & Tomoko Funazo & Hitomi Ajimizu & Takashi Nomizo & Hironori Yoshida & Hiroyuki Katsuragawa & Kentaro Tsuji & Noritaka Sano & Shigeki Takada & Yohei Mineharu & Shigeto Nishikawa & Toshi Menju & Akihiko Yoshizawa & Yoshiki Arakawa & Hiroaki Wake & Toyohiro Hirai
- 1-21 Adipocyte small extracellular vesicle-derived microRNA-30a-3p exacerbates hepatic steatosis in high fat diet-fed male mice
by Tian Zhang & Longkun Hu & Diao Chen & Yongxin Chen & Fei Zhou & Ruohan Lou & Yuxia Zhou & Yuanyuan Wang & Mingjun Shi & Ke-Gang Linghu & Ligen Lin & Bing Guo
- 1-21 Assembly of two functionally-distinct protein import complexes in the outer membrane of plant chloroplasts
by Sreedhar Nellaepalli & Domagoj Baretić & Astrid F. Brandner & Sybille Kubis-Waller & Duorong Xu & Ziad Soufi & Shuyang Cheng & Sireesha Kodru & Jun Fang & Úrsula Flores-Pérez & Vaishnavi Ravikumar & Pablo Pulido & Marjorie Fournier & Ivan Ahel & Syma Khalid & R. Paul Jarvis
- 1-21 Regionalized regulation of actomyosin organization influences cardiomyocyte cell shape changes during chamber curvature formation
by Dena M. Leerberg & Gabriel B. Avillion & Rashmi Priya & Didier Y. R. Stainier & Deborah Yelon
- 1-21 The SnRK1–RAP2.4h–PIP2 module contributes to the trade-off between growth and hypoxia tolerance in plants
by Ke Liao & Lin-Na Wang & Xin-Yu Lu & Hui-Min Zhang & Zhong-Rong Yan & Tian-Yi Zhang & Yi Li & Ling-Jing Xu & Qiao-Ling Zhong & Qin-Fang Chen & Ying Zhou & Ruo-Han Xie & Shi Xiao
- 1-21 BRD4 directs myofiber identity and metabolic adaptation through CHD4 cooperation
by Zheng Zhou & Lin Liu & Zhisheng Xu & Danxia Zhou & Anqi Liu & Jiachen Yuan & Gonghao Shen & Qiqi Guo & Yujing Yin & Yan Mao & Wanping Sun & Liwei Xiao & Cheng Lv & Abdukahar Kiram & Likun Yang & Yuhuan Jia & Lu Ke & Lei Fang & Weiqin Li & Tingting Fu & Zhenji Gan
- 1-21 DDX6 undergoes phase separation to modulate metabolic plasticity and chemoresistance
by Hongjie Bi & Wei Li & Lili Ren & Honghai Zhang & Lei Dong & Anthony Chan & Xueer Wang & Lu Yang & Xiaoxu Zhang & Meilin Xue & Hanjun Qin & Xiwei Wu & Johanna Ten Hoeve-Scott & Bin Zhang & Ling Li & Mark Wunderlich & James C. Mulloy & Steven T. Rosen & Jianjun Chen & Xiaobo Li & Chun-Wei Chen & Rui Su
- 1-21 Regulation of physical activity and energy expenditure through Phf6 in the medial preoptic area
by Jingjie Wang & Bing Liu & Xiaohua Wu & Jingjing Sun & Yaxin Wang & Liang He & Linhua Gan & Xiangfeng Du & Jingyu Ruan & Lingzhi Pi & Qing-Feng Wu & Ju Huang
- 1-21 Mapping functional non-coding variation in individual human genomes through haplotyping, multiomics, and deep learning
by Mikhail D. Magnitov & Robin H. van der Weide & Aster F. Witvliet & Miguel Hernández-Quiles & Moreno Martinović & Hans Teunissen & Luca Braccioli & Michiel Vermeulen & Elzo de Wit
- 1-21 PCSK5 promotes angiogenesis and cardiac repair after myocardial infarction
by Jieyu Guo & Siyu Ma & Jinghua Ma & Ming Liu & Fei Ge & Xinhong Wang & Jiayi Lin & Nan Jiang & Xiaoke Lin & Zhipeng Lian & Zheng Zuo & Liliang Li & Genmao Cao & Yongbo Li & Xiangxiang Wei & Xianlong NG & Xiuling Zhi & Elena Osto & Yuxiang Dai & Jun Li & Lixin Wang & Hong Jiang & Dan Meng
- 1-21 Intrinsic mechanisms and microenvironmental cues fine-tune plasticity of esophageal progenitors
by Louison Descampe & Benjamin Dassy & Fadi Charara & Ligia Craciun & Laurine Verset & Sheleya Pirard & Quentin Verheye & Morgane Leprovost & Marie Isabelle Garcia & Alizée Vercauteren Drubbel & Benjamin Beck
- 1-21 Two distinct SWI/SNF complexes direct chromatin-linked transcriptional programs in Toxoplasma
by Dominic Schwarz & Benicio Tapia & Sebastian Lourido
- 1-21 Heterogeneous endocrine cell composition defines human islet functional phenotypes
by Carmella Evans-Molina & Yasminye D. Pettway & Diane C. Saunders & Seth A. Sharp & Thomas SR. Bate & Han Sun & Heather Durai & Shaojun Mei & Anastasia Coldren & Corey Davis & Conrad V. Reihsmann & Alexander L. Hopkirk & Jay Taylor & Amber Bradley & Radhika Aramandla & Greg Poffenberger & Adel Eskaros & Regina Jenkins & Danni Shi & Ke Xu & Hakmook Kang & Varsha Rajesh & Swaraj Thaman & Fan Feng & Jean-Philippe Cartailler & Alvin C. Powers & Kristin Abraham & Anna L. Gloyn & Joyce C. Niland & Marcela Brissova
- 1-21 Microbiota-derived IPA protects against colitis by regulating intestinal HMGCS2-mediated ketogenesis to facilitate mucosal healing
by Yanan Zhang & Shuyu Tu & Xian Shao & Jinxin Meng & Zhuobiao Zhang & Wei Wei & Xuping Jing & Zhewen Qin & Jianan Wu & Weilv Xu & Bofei Dong & Jinsong Gao & Aijuan Qu & Shuxian Chen & Li Zhang & Peng Gong & Bo Shan & Hui Shi & Shu Jeffrey Zhu
- 1-21 Activation of hypothalamic-pontine-spinal pathway promotes locomotor initiation and functional recovery after spinal cord injury in mice
by Chengyue Ji & Yunfan Zhang & Zeyu Lin & Ziqi Zhao & Zhuolei Jiao & Zhiyuan Zheng & Xiaoxue Shi & Xiaofei Wang & Ziyu Li & Shuisheng Yu & Yun Qu & Yaxuan Wei & Tan Rui & Bowen Zheng & Taorong Xie & Hanyu Shi & Qifang Wang & Xiao Yu & Xiaohong Xu & Juxiang Chen & Jin Fan & Weihua Cai & Yi Li
- 1-21 Dysregulation of macrophage lipid metabolism underlies intracellular bacterial neuroinvasion
by Zhou Sha & Kun Yang & Shoupeng Fu & Xiaoyong Tong & Hui Yang & Huiling Fang & Qianqian He & Ning Li & Xinyu Shu & Qi Liu & Beibei Fu & Jin Liu & Qian Li & Hao Zeng & Xiaokai Zhang & Rui Yao & Xushuo Zhang & Wenjin Guo & Xuhu Mao & Mian Long & Xiaoyuan Lin & Quanming Zou & Haibo Wu
- 1-21 Targeting a super-enhancer induced aldehyde dehydrogenase metabolic loop mitigates CDK4/6 inhibitor resistance in estrogen receptor-positive cancers
by Xiaochuan Chen & Shini Liu & Dandong Luo & Dezheng Lin & Jun Liu & Huanmiao Zhan & Shuqin Chen & Peng Deng & Zhaoliang Yu
- 1-21 DPEP2 suppresses hyperinflammation via metabolic reprogramming of macrophages in sepsis
by Wenchen Luo & Wei Xu & Qimeng Yin & Jieqiong Song & Jie Wang & Yian Guan & Jian Huang & Jian Yu & Kefeng Zou & Danfeng Jin & Chao Xu & Min Qiu & Zhixin Qiu & Jing Zhong
- 1-21 A SET domain-containing protein and HCF-1 maintain transgenerational epigenetic memory
by Chenming Zeng & Giulia Furlan & Miguel Vasconcelos Almeida & Juan C. Rueda-Silva & Jonathan Price & Helena Santos-Rosa & Jingxiu Xu & Yan Kuang & Enric Cata Socias & Jonas Mars & Pedro Rebelo-Guiomar & Meng Huang & Shouhong Guang & Falk Butter & Eric A. Miska
- 1-21 Mapping histologic and functional maturation of human endocrine pancreas across early postnatal periods
by Diane C. Saunders & Fan Feng & Alexander L. Hopkirk & Kristie I. Aamodt & Nathaniel Hart & Fong Cheng Pan & Conrad V. Reihsmann & Nike Izmaylov & Shaojun Mei & Brandon A. Sherrod & Corey Davis & Nongyao Nonpanya & Yasminye D. Pettway & Keval P. Patel & Kai S. Lee & Jeff Duryea & Rachana Haliyur & Radhika Aramandla & Heather Durai & Greg Poffenberger & Alexandra Martin & Amanda L. Posgai & Irina Kusmartseva & Maria L. Beery & Mingder Yang & Ke Xu & Hakmook Kang & Dale L. Greiner & Leonard D. Shultz & Jean-Philippe Cartailler & Rita Bottino & Mark A. Atkinson & Christopher V. E. Wright & Alvin C. Powers & Marcela Brissova
- 1-21 Persistent representation of a prior schema in the orbitofrontal cortex facilitates learning of a conflicting schema
by Ido Maor & James Atwell & Ilana Ascher & Yuan Zhao & Yuji K. Takahashi & Evan Hart & Francisco Pereira & Geoffrey Schoenbaum
- 1-21 TMEM120A maintains adipose tissue lipid homeostasis through ER CoA channeling
by Yoon Keun Cho & Junhyuck Lee & Yujin L. Jeong & Minki Shim & Xuan Linh Mai & Chang Seomoon & Cheol Woon Jung & Yoon Ha Choi & Sik Namgoong & Young-Suk Jung & Sung Won Kwon & Juyong Lee & Je Kyung Seong & Sunghyouk Park & Emilio P. Mottillo & James G. Granneman & Dong-Kyu Lee & Jong Kyoung Kim & Yun-Hee Lee
- 1-21 Time-dependent deployment of medial prefrontal cortical representations in male mice
by Junior Samuel Lopez-Yepez & Anna Barta & Juliane Martin & Maria Moltesen & Tsz-Fung Woo & Oliver Hulme & Ebru Demir & Duda Kvitsiani
- 1-21 Multi-modal AI for opportunistic screening, staging and progression risk stratification of steatotic liver disease
by Yuan Gao & Chunli Li & Wanxing Chang & Bai Du & Xianghua Ye & Yee Hui Yeo & Yingda Xia & Heng Guo & Xiaoming Zhang & Wei Liu & Ruobing Bai & Beibei Li & Yang Hong & Jiawen Yao & Le Lu & Kai Cao & Ke Yan & Jun Chen & Jie Li & Yang Hou & Ling Zhang & Yu Shi
- 1-21 Adaptation to cystine limitation stress confers a targetable lipid metabolism vulnerability in pancreatic ductal adenocarcinoma
by Yunzhan Li & Zekun Li & Qin Li & Dongxiao Sun & Bo Ni & Mingjun Tan & Ashley E. Shay & Min Wang & Chenyang Meng & Guangcong Shen & Boyang Fu & Yueying Shan & Shiqi Zhang & Rifah Rownak Tanshee & Tianxing Zhou & Yongjie Xie & Kun-Ming Chen & Bin Qiao & Yunkun Dang & Scot R. Kimball & Guanshi Zhang & Girish H. Rajacharya & Pankaj K. Singh & Xiuchao Wang & Jihui Hao & Shengyu Yang
- 1-21 Polar chromosomes are rescued from missegregation by spindle elongation-driven microtubule pivoting
by Isabella Koprivec & Valentina Štimac & Mario Đura & Kruno Vukušić & Petra Mikec & Iva M. Tolić
- 1-21 FGFR signaling establishes spatial gradients of secretory cell identities along the airway proximal-distal axis
by Alexandros Sountoulidis & Jonas Theelke & Andreas Liontos & Alexandra B. Firsova & Orane Eliot & Janine Koepke & Pamela Millar-Büchner & Louise Mannerås-Holm & Åsa Björklund & Athanasios Fysikopoulos & Antonia Kelm & Eleni Bouloukou & Konstantin Gaengel & Fredrik Bäckhed & Christer Betsholtz & Werner Seeger & Saverio Bellusci & Christos Samakovlis
- 1-21 Cross-species comparison of amniote single-cell transcriptomes reveals evolutionary conservation and divergence in the chicken immune system
by Fei Wang & Jilong Ren & Yaqi Zhou & Wuqiang Huo & Huichao Liu & Mumu Qin & Yi Jing & Zhongtao Yin & Tao Shi & Huiquan Shan & Guanghui Tan & Haoping Wang & Xi Guo & Junpu Mei & Zhen Yue & Zhuocheng Hou & Huaijun Zhou & Jiuzhou Song & Søren Egedal Degn & Lin Lin & Yonglun Luo & Feilong Meng & Xiaodong Fang & Haihan Zhang & Xi He & Lingzhao Fang & Yu Jiang
- 1-21 Prodrug nanoplatform for triggering ferroptosis to eliminate senescent cells in age-associated pathologies
by Chengkang Jin & Xiaoling Xu & Ning Yao & Hairui Zhang & Changjiang Chen & Lingyao Zeng & Zhiyun Liu & Lanjie Lei & Shumao Cui & Chengping Wen & Liyun Shi
- 1-21 Towards robust foundation models for digital pathology
by Jonah Kömen & Edwin D. de Jong & Julius Hense & Hannah Marienwald & Jonas Dippel & Philip Naumann & Eric Marcus & Lukas Ruff & Maximilian Alber & Jonas Teuwen & Frederick Klauschen & Klaus-Robert Müller
- 1-21 Rapid endothelialization of printed vascular grafts by perivascular niche-circulating endothelial progenitors crosstalk
by Zhe-qian Zhang & Ping-Ping Yuan & Cong Yao & Yu-xin Lu & Yi-dong Hu & Zhen-nan Qiu & Wen-yu Zhan & Xin-chi Zhang & Yu-jiao Wang & Xiao-peng Wu & Ya-jing Zhao & Peng-yu Wang & Ning Leng & Cun Zhang & Jian-kang He & Wei Wu
- 1-21 Mechanical rejuvenation of senescent stem cells and aged bone via chromatin remodeling
by Xiaojing Liu & Yuanxin Ye & Zhonghan Li & Li Liao & Qiang Wei
- 1-21 Leveraging genomic and transcriptomic data of diverse ancestry to uncover mechanisms of psychiatric risk in the adult and developing brain
by Aarti Jajoo & Vijetha Balakundi & Chris Chatzinakos & Athina Aruldass & Cindy Wen & Ilse G. C. Kolmans & Artemis Iatrou & Joel E. Kleinman & Kerry J. Ressler & Tim Bigdeli & Michael J. Gandal & Nikolaos P. Daskalakis
- 1-21 Spatiotemporal dynamics of the human cortical functional hierarchy across the lifespan
by Qiongling Li & Xinyuan Liang & Debin Zeng & Tengda Zhao & Xuhong Liao & Gaolang Gong & Qian Wang & Chenxuan Pang & Qian Yu & Xiaoxi Dong & Yirong He & Yanchao Bi & Pindong Chen & Rui Chen & Yuan Chen & Taolin Chen & Jingliang Cheng & Yuqi Cheng & Zaixu Cui & Zhengjia Dai & Yao Deng & Yuyin Ding & Qi Dong & Dingna Duan & Jia-Hong Gao & Qiyong Gong & Ying Han & Zaizhu Han & Chu-Chung Huang & Ruiwang Huang & Ran Huo & Lingjiang Li & Ching-Po Lin & Qixiang Lin & Bangshan Liu & Chao Liu & Ningyu Liu & Ying Liu & Yong Liu & Jing Lu & Leilei Ma & Weiwei Men & Shaozheng Qin & Wen Qin & Jiang Qiu & Shijun Qiu & Tianmei Si & Shuping Tan & Yanqing Tang & Sha Tao & Dawei Wang & Fei Wang & Jiali Wang & Pan Wang & Xiaoqin Wang & Yanpei Wang & Dongtao Wei & Yankun Wu & Peng Xie & Xiufeng Xu & Yuehua Xu & Zhilei Xu & Liyuan Yang & Chunshui Yu & Huishu Yuan & Zilong Zeng & Haibo Zhang & Xi Zhang & Gai Zhao & Yanting Zheng & Suyu Zhong & Mingrui Xia & Shuyu Li & Yong He
- 1-21 MELK inhibition disrupts actin cytoskeleton and broadly restricts human coronavirus infections
by Kuai Yu & Qiaorui Yao & Dong Wang & Qingtao Hu & Dandan Li & Fang Li & Fenghua Chen & Jingyi Su & Ting Huang & Qing Zhang & Zishuo Lin & Wei Ran & Yiliang Wang & Yuzheng Zhou & Shuai Wen & Yuting Lin & Yaming Jiu & Jingxian Zhao & Jincun Zhao
- 1-21 Peptide-functionalized membrane camouflage for endogenous H2S-induced photothermal immunotherapy of orthotopic colorectal cancer
by Kai Cheng & Fang Zhang & Jia-Hua Zou & Xiao-Ling Lei & Xiao-Ting Xie & Yan-Bin Guo & Guo-Ping Wang & Bo Liu & Yuan-Di Zhao & Jiang Xia & Jin-Xuan Fan
- 1-21 Targeting phenol-soluble modulin α3-driven M1 macrophage polarization and necroptosis mitigates MRSA infection in mice
by Bo Ma & Zhi Li & Hua Xu & Yuting Chen & Yingchao Fang & Jianwei Xie
- 1-21 Phosphorylation of SF3B1 by CDK11 orchestrates spliceosome activation via SNIP1-dependent RES complex recruitment
by Pavla Gajdušková & Igor Ruiz de Los Mozos & Milan Hluchý & Antonina Myšková & Kateřina Zábrady & Peter Maník & Neda Dragišić & Kateřina Hanáková & David Potěšil & Sara Bologna & Jiří Nováček & Caroline C. Friedel & Konstantinos Tripsianes & Zbyněk Zdráhal & Dalibor Blazek
- 1-21 Mapping rare protein-coding variants on multi-organ imaging traits
by Yijun Fan & Jie Chen & Zirui Fan & Julio Chirinos & Jason L. Stein & Patrick F. Sullivan & Rujin Wang & Ajay Nadig & David Y. Zhang & Shuai Huang & Zhiwen Jiang & Peter Yi Guan & Xinjie Qian & Ting Li & Haoyue Li & Zehui Sun & Marylyn D. Ritchie & Joan M. O’Brien & Walter Witschey & Daniel J. Rader & Tengfei Li & Hongtu Zhu & Bingxin Zhao
- 1-21 ASO therapy rescues NOTCH2NLC GGC repeat expansion-induced genomic damage, 3D chromatin structural abnormalities, and senescence
by Mengjie Li & Mibo Tang & Xiaoyan Hao & Zhengwei Hu & Dongrui Ma & Shuangjie Li & Chunyan Zuo & Zhiyun Wang & Yuanyuan Liang & Yanmei Feng & Chenwei Hao & Chen Wang & Huanyu Li & Yalan Yang & Yuemeng Sun & Shasha Qi & Chengyuan Mao & Yuming Xu & Qun Wang & De Yang & Ruwei Yang & Ziyao Zhou & Peilin Ji & Song Tan & Zaiqiang Zhang & Hao Chen & Albert R. La Spada & Changhe Shi
- 1-21 α-Synuclein aggregates induce mitochondrial damage and trigger innate immunity to drive neuron–microglia communication
by Ranabir Chakraborty & Stephanie Maya & Veronica Testa & Jara Montero-Muñoz & Takashi Nonaka & Masato Hasegawa & Antonella Consiglio & Chiara Zurzolo
- 1-21 Fidelity in co-diversified symbiosis
by Inès Pons & Marleny García-Lozano & Christiane Emmerich & Aftab Mahmood Ayas & Christine Henzler & Hagay Enav & Ruth E. Ley & Hassan Salem
- 1-21 HIF sustain a transcriptional regulatory circuit of EPAS1 expression in renal clear cell carcinoma
by Stephanie Naas & René Krüger & Steffen Grampp & Victoria Lauer & Andre Kraus & Julia Naas & Fabian Müller & Franziska Gsottberger & Mario Schiffer & Bernd Wullich & Arndt Hartmann & Marc P. Stemmler & Johannes Schödel
- 1-21 Conserved and divergent gene regulatory networks for crop drought resistance
by Xianzhi Deng & Liangsheng Shi & Yu Wang & Han Qiao & Xin Wang & Jiateng Ma & Yufan Zhang & Yuanyuan Zha & Xiaolong Hu
- 1-21 MeCP2 gene dosage-dependent neurodevelopmentally restricted defects arise by aberrant activation of cell fate-determining bivalent genes
by Mirko Luoni & Michal Kubacki & Serena Gea Giannelli & Francesca Morosi & Claudia Di Berardino & Angelo Iannielli & Alessandro Sessa & Gaia Colasante & Emanuele Di Patrizio Soldateschi & Chiara Lanzuolo & Vania Broccoli
- 1-21 Molecular anatomy of PLK1 master docking motifs
by Long Ren & Arianna Esposito-Verza & Raphael Gasper & Marion E. Pesenti & Petra Janning & Franziska Müller & Carolin Koerner & Petra Geue & Sabine Wohlgemuth & Ingrid R. Vetter & Andrea Musacchio
- 1-21 Stenotrophomonas promotes gastrointestinal tumor progression via STING degradation in tumour cells and mitigated immune response
by Huolun Feng & Kunling Chen & Zhihui Xi & Baijin Xia & Xi Chen & Yiqin Huang & Zuda Huang & Jieqing Guo & Dandan Zhu & Fa Ling & Jianlong Zhou & Yuhan Zhang & Yucheng Zhang & Yongfeng Liu & Wenxing Zhang & Jiatong Lin & Zejian Lyu & Qunsheng Huang & Junjiang Wang & Tieying Hou & Jiabin Zheng & Fan Xing & Yong Li
- 1-21 Predicting individual differences of fear and cognitive learning and extinction
by C. A. Gomes & D. R. Bach & A. Razi & G. Batsikadze & S. Elsenbruch & H. Engler & T. M. Ernst & M. C. Fellner & C. Fraenz & E. Genç & A. Klass & F. Labrenz & S. Lissek & C. J. Merz & D. Metzen & A. Nostadt & R. J. Pawlik & J. E. Schneider & M. Tegenthoff & A. Thieme & O. T. Wolf & O. Güntürkün & H. H. Quick & R. Kumsta & D. Timmann & T. Spisak & N. Axmacher
- 1-21 Complex I protein NDUFB9 is a metabolic vulnerability in triple negative breast cancer brain metastases
by Mingxi Lin & Zhexu Wen & Cheng Zeng & Yizi Jin & Teng Zhou & Yuxin Yan & Shenglin Huang & Xin Hu & Xiaoxiang Guan & Xichun Hu & Jian Zhang
- 1-21 CD38⁺ endothelial remodeling marks spatially patterned vasculopathy in rapidly advancing periodontitis and peri-implantitis
by Quinn T. Easter & Khoa L. A. Huynh & Camila Schmidt Stolf & Jialiu Xie & Bruno F. Matuck & Akira Hasuike & Zabdiel Alvarado-Martinez & William S. Kim & Zhaoxu Chen & Apoena Aguiar Ribeiro & Nivedita Pareek & Andrea M. Azcarate-Peril & Di Wu & Renato Casarin & Kang I. Ko & Jinze Liu & Kevin M. Byrd
- 1-21 Endosome maturation is orchestrated by inside-out proton signaling through a Na+/H+ exchanger and pH-dependent Rab GTPase cycling
by YouJin Lee & Qing Ouyang & Li Ma & Morgan Fleishman & Hasib Aamir Riaz & Michael Schmidt & Jeffrey L. Dupree & Anupam Mondal & Priyesh Mohanty & Jeetain Mittal & Oliver Beckstein & David G. Lambright & Eric M. Morrow
- 1-21 Autophagic extracellular vesicles (AEVs) are distinct from exosomes and play crucial roles in viral infections
by Kedan Mao & Fangfang Huo & Hongqi Wei & Furong Wang & Sidong Xiong & Yuxuan Fu
- 1-21 A gut microbiome-kidney-heart axis predictive of future cardiovascular diseases
by Kanta Chechi & Rima Chakaroun & Antonis Myridakis & Sofia K. Forslund-Startceva & Sebastien Fromentin & Trine Nielsen & Judith Aron-Wisneswky & Eugeni Belda & Edi Prifti & Pierre Bel Lassen & Gwen Falony & Sara Vieira-Silva & Julien Chilloux & Kazuhiro Sonomura & Lesley Hoyles & Laura Martinez-Gili & Francesco Pallotti & Petros Andrikopoulos & Francesc Puig-Castellví & Romina Pacheco Tapia & Inés Castro-Dionicio & Hugo Roume & Nicolas Pons & Emmanuelle Le Chatelier & Benoit Quinquis & Nathalie Galleron & Magali Berland & Michael T. Olanipekun & Manyi Jia & Angelos Manolias & Bridget Holmes & Solia Adriouch & Matthias Blüher & Luis Pedro Coelho & Kévin Da Silva & Pilar Galan & Boyang Ji & Ana Luisa Neves & Christine Rouault & Joe-Elie Salem & Valentina Tremaroli & Tue H. Hansen & Nadja B. Søndertoft & Christian Lewinter & Helle K. Pedersen & Peter D. Mark & Jens P. Goetze & Lars Køber & Henrik Vestergaard & Torben Hansen & Jean-Daniel Zucker & Taka-Aki Sato & Serge Hercberg & Fredrik Bäckhed & Ivica Letunic & Jean-Michel Oppert & Jens Nielsen & Jeroen Raes & Ioanna Tzoulaki & Abbas Dehghan & Verena Zuber & Emmanuelle Bouzigon & Mark Lathrop & Parminder Raina & Philippe Froguel & Fumihiko Matsuda & Florence Demenais & Dominique Gauguier & Michael Stumvoll & Peer Bork & Oluf Pedersen & S. Dusko Ehrlich & Karine Clément & Marc-Emmanuel Dumas
- 1-21 Transgenic hookworm secretes anti-tetrodotoxin human single chain antibody
by Kumar Sachin Singh & Suman Bharti & Bruce A. Rosa & Mahdiyeh Bigham & Samuel C. Uzoechi & Young-Jun Choi & John C. Martin & Danielle Kemper & Slavica Pavlovic Djuranovic & Darren A. Pickering & Rachael Ryan & Bethany K. Bracken & Maria Elena Bottazzi & Eric C. Carnes & Wannaporn Ittiprasert & Matthew Moyle & Paul J. Brindley & Alex Loukas & Sergej Djuranovic & Makedonka Mitreva
- 1-21 Priming versus propagating: distinct immune effects of alpha- versus beta-particle emitting radiopharmaceuticals when combined with immune checkpoint inhibition in mice
by Caroline P. Kerr & Won Jong Jin & Peng Liu & Joseph J. Grudzinski & Carolina A. Ferreira & Hansel Comas Rojas & Alejandro J. Oñate & Ohyun Kwon & Meredith Hyun & Malick Bio Idrissou & René Welch Schwartz & Jessica M. Vera & Paul A. Clark & Adedamola Adeniyi & Maya Takashima & Amy K. Erbe & Amanda G. Shea & Maria Powers & Anatoly N. Pinchuk & Christopher F. Massey & Cynthia Choi & Reinier Hernandez & Bryan P. Bednarz & Irene M. Ong & Jamey P. Weichert & Zachary S. Morris
- 1-21 Global remapping of the sensory homunculus emerges early in childhood development
by Raffaele Tucciarelli & Laura Bird & Zdenek Straka & Maggie Szymanska & Mathew Kollamkulam & Harshal Arun Sonar & Jamie Paik & Danielle Clode & Matej Hoffmann & Dorothy Cowie & Tamar R. Makin
- 1-21 Conducting polymer-stabilized nanozymes alleviate sepsis-induced myocardial injury by inhibiting iron accumulation and lipid peroxidation
by Tingting Wu & Ying Liu & Wei Wang & Rong Sun & Yanyan Wang & Jiangpeng Pan & Jingfei Zhu & Kelong Fan & Qiuran Xu & Wei Jiang
- 1-21 A pathogenic Tau mutation drives autophagy-lysosome dysfunction that limits Tau degradation in a model of frontotemporal dementia
by Farzaneh S. Mirfakhar & Jacob A. Marsh & Chihiro Sato & Kylie J. Schache & Miguel A. Minaya & Roland E. Dolle & Stephen C. Pak & Gary A. Silverman & David H. Perlmutter & Shannon L. Macauley & Celeste M. Karch
- 1-21 Chondrocytes reprogram chromatin in hypoxic microenvironments to activate CADM1-AS1/HDAC1 complex-mediated anti-inflammation signals
by Weiyu Ni & Tianyuan Gu & Panyang Shen & Zixuan Mei & Yizheng Wu & Kamuran Yilamu & Nan Pan & Wentao Yang & Gang Liu & Yan Ma & Xiangqian Fang & Shunwu Fan & Haitao Zhang & Shuying Shen
- 1-21 Eye movements during free viewing to maximize scene understanding
by Shravan Murlidaran & Miguel P. Eckstein
- 1-21 Tumor metabolic adaptation induced by L-asparaginase reveals a vulnerability to PARP1/2 inhibitor in B-cell lymphomas
by Anaïs Aussel & Ivan Nemazanyy & Ashaina Vandenberghe & Pauline Meola & Noémie Dorat & Rachel Paul & Lama Habbouche & Laurie Exposito & Nicolas Nottet & Virginie Petrilli & Edmond Chiche & Nicolas Mounier & Sandrine Marchetti & Cédric Chaveroux & Jean-Ehrland Ricci & Johanna Chiche
- 1-21 Evolutionary remodeling of ubiquinone biosynthesis in Toxoplasma gondii reveals an essential bi-functional monooxygenase
by Baihetiya Baierna & Taufiq Rahman & Scott Latimer & Gilles J. Basset & Silvia N. J. Moreno
- 1-21 Decoding immunotherapy response through computational modeling
by Bingrui Li & Ruihan Luo & Kexin Huang & Jiajia Liu & Weiling Zhao & Xiaobo Zhou
- 1-21 dHyperCas12a enables multiplexed CRISPRi screens
by Schuyler M. Melore & Christian D. McRoberts Amador & Marisa C. Hamilton & Charles A. Gersbach & Timothy E. Reddy
- 1-21 D-π-A sensitized carbon dots as long-lived type-I/Ⅱ photosensitizers for NIR-excited hypoxia-regulated photodynamic therapy
by Zhenlin Zhang & Lang Yan & Weiwei Li & Jinyan Hu & Yang Wang & Hongjing Dou & Dengyu Pan & Longxiang Shen & Sheng Shi & Bijiang Geng
- 1-21 Natural degradation of RNA polymerase II is essential for oocyte chromatin reorganization and maternal-to-zygotic transition
by Jing Wang & Wang Li & Jing Guo & Xiaoming Xu & Ge Lin & Bin Li & Chun So
- 1-21 Iron deficiency induces maturation-dependent loss of pancreatic β-cells
by Annelore Van Mulders & Lien Willems & Sophie Coenen & Stephanie Bourgeois & Xiaoyan Yi & Yue Tong & Gunter Leuckx & Yves Heremans & Julie Pierreux & Laure Degroote & Toshiaki Sawatani & Chiara Vinci & Gamze Ates & Ann Massie & Françoise Carlotti & Eelco de Koning & Thomas Mandrup-Poulsen & Clara Zelinsky & Steven Goderis & Bart Ghesquière & Raphael Scharfmann & Miriam Cnop & Nico De Leu & Willem Staels
- 1-21 Proviral NUP153 binding to viral proteins and RNA regulates structural–nonstructural protein ratios in orthoflavivirus infection
by Marie B. A. Peters & Richard Lindqvist & Eszter Kassa & Wai-Lok Yau & Pallabi Sengupta & Isabell Niedermoser & Gisa Gerold & Nasim Sabouri & Ylva Ivarsson & Richard Lundmark & Anna K. Överby
- 1-21 Urolithin A activates aryl hydrocarbon receptor-NLRP6-mediated pathways in intestinal epithelial cells to modulate mucosal immunity and strengthen gut barrier integrity
by Sweta Ghosh & Zachary M. Vanwinkle & Sobha Rani Bodduluri & Subir Kumar Juin & Mahendar Kadari & Ankita Singh & Gerald W. Dryden & Matthew B. Lawrenz & Thirumala-Devi Kanneganti & Shesh N. Rai & Misty Good & Pawan Kumar & Bodduluri Haribabu & Venkatakrishna Rao Jala
- 1-21 Cross-ancestry comparison of aptamer and antibody protein measures
by Jayna C. Nicholas & Daniel H. Katz & Usman A. Tahir & Catherine L. Debban & Francois Aguet & Thomas Blackwell & Russell P. Bowler & K. Alaine Broadaway & Jingsha Chen & Clary B. Clish & Josef Coresh & Elaine Cornell & Daniel E. Cruz & Rajat Deo & Margaret F. Doyle & Peter Durda & Lynette Ekunwe & James S. Floyd & Dipender Gill & Xiuqing Guo & Ron C. Hoogeveen & Craig Johnson & Leslie A. Lange & Yun Li & Alisa Manning & James B. Meigs & Michael Y. Mi & Josyf C. Mychaleckyj & Nels C. Olson & Katherine A. Pratte & Brucy M. Psaty & Alexander P. Reiner & Peifeng Ruan & Magdalena Sevilla-Gonzalez & Amil M. Shah & Quan Sun & Russell P. Tracy & Jia Wen & Alexis C. Wood & James G. Wilson & Kristin L. Young & Bing Yu & Mary R. Rooney & Ani Manichaikul & Ruth Dubin & Karen L. Mohlke & Stephen S. Rich & Jerome I. Rotter & Peter Ganz & Robert E. Gerszten & Kent D. Taylor & Laura M. Raffield
- 1-21 Neural and computational mechanisms underlying one-shot perceptual learning in humans
by Ayaka Hachisuka & Jonathan D. Shor & Xujin Chris Liu & Daniel Friedman & Patricia Dugan & Ignacio Saez & Fedor E. Panov & Yao Wang & Werner Doyle & Orrin Devinsky & Eric K. Oermann & Biyu J. He
- 1-21 Epilepsy-associated FOXJ3 variants link a transcriptional program of the PTEN-mTOR pathway to neuronal specification and cortical lamination
by Haw-Yuan Cheng & Chen Liu & Chiao-Wen Nien & Hui-Chin Huang & Hong-Jun Zhao & Fang-Shin Nian & Chien Chen & Helena Martins Custodio & Sanjay M. Sisodiya & Chien Lu & Hsin-Hung Chen & Chih-Sin Hsu & Wen-Chieh Pi & Chia-Chi Chu & Jacob Shu-Jui Hsu & Pei-Lung Chen & Fu-Pang Chang & Chien-Yi Tung & Shen-Ju Chou & Shahryar Alavi & Henry Houlden & Wei-Yi Chen & Yo-Tsen Liu & Pei-Shan Hou & Jin-Wu Tsai
- 1-21 Vitamin D binding protein induces skeletal muscle atrophy and contributes to cancer-associated muscle wasting independently of vitamin D status in preclinical models
by Tommaso Raiteri & Simone Reano & Andrea Scircoli & Ivan Zaggia & Alessandro Antonioli & Stefania Faletti & Francesco Favero & Marcello Manfredi & Giuliana Pelicci & Davide Corà & Lorenza Scotti & Richard R. Kew & Flavia Prodam & Paolo E. Porporato & Nicoletta Filigheddu
- 1-21 Nested spatiotemporal theta–gamma waves organize hierarchical processing across the mouse visual cortex
by Brendan Harris & Pulin Gong
- 1-21 Functional distinctions between orbitofrontal cortex and anterior cingulate cortex subregions in decision-making and autonomic regulation
by Georgios K. Papageorgiou & Ken-ichi Amemori & Daniel J. Gibson & Helen N. Schwerdt & Michelangelo Naim & Michelle C. Wang & Tomoko Yoshida & Jitendra Sharma & Urvashi Upadhyay & Guangyu Robert Yang & Ann M. Graybiel
- 1-21 Design of precision therapeutics for a CKD risk allele by targeting Shroom3-Rock interaction
by Anand Reghuvaran & Ashwani Kumar & Qisheng Lin & Nallakandi Rajeevan & Khadija Banu & Zeguo Sun & Hongmei Shi & Gabriel Barsotti & EM Tanvir & John Pell & Sudhir Perincheri & Chengguo Wei & Bhavya Bharathan & Marina Planoutene & Anne Eichmann & Valeria Mas & Weijia Zhang & Lloyd G. Cantley & Leyuan Xu & Bhaskar Das & John Cijiang He & Madhav C. Menon
- 1-21 Precipitation disaster hotspots depend on historical climate variability
by Iris de Vries & Maybritt Schillinger & Erich Fischer & Sebastian Sippel & Reto Knutti
- 1-21 A CD8αβ co-receptor modified to contain an intracellular CD28 signaling tail enhances TCR-engineered T cell function independent of solid-tumor-associated co-stimulatory ligands
by Shihong Zhang & Tzu-Hao Tang & Sinéad Kinsella & Francesco Mazziotta & Michael T. Schweizer & Megan S. McAfee & Ariunaa Munkhbat & Yapeng Su & Valentin Voillet & Lauren E. Martin & Colton W. Smith & Yuta Asano & Menna Hailemariam & Jakob Bakhtiari & Bo Lee & Cecilia Yeung & Hung Chen & Alessandro M. Rizzi & Daniel G. Chen & Kelsey Furiya & Nick Horst & Tianzi Zhang & Phung Le & Kelly McKenna & Shannon K. Oda & Anthony Rongvaux & Phillip D. Greenberg & Thomas M. Schmitt & Aude G. Chapuis
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