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Content
December 2025, Volume 16, Issue 1
- 1-21 L3MBTL3 and STAT3 collaboratively upregulate SNAIL expression to promote metastasis in female breast cancer
by Jianpeng Xiao & Jie Wang & Jialun Li & Jie Xiao & CuiCui Liu & Libi Tan & Yanhong Tu & Ruifang Yang & Yujie Pei & Minghua Wang & Jiemin Wong & Binhua P. Zhou & Jing Li & Jing Feng
- 1-21 Potentially causal associations between placental DNA methylation and schizophrenia and other neuropsychiatric disorders
by Ariadna Cilleros-Portet & Corina Lesseur & Sergi Marí & Marta Cosin-Tomas & Manuel Lozano & Amaia Irizar & Amber Burt & Iraia García-Santisteban & Diego Garrido-Martín & Geòrgia Escaramís & Alba Hernangomez-Laderas & Raquel Soler-Blasco & Charles E. Breeze & Bárbara P. Gonzalez-Garcia & Loreto Santa-Marina & Jia Chen & Sabrina Llop & Mariana F. Fernández & Martine Vrijheid & Jesús Ibarluzea & Mònica Guxens & Carmen Marsit & Mariona Bustamante & Jose Ramon Bilbao & Nora Fernandez-Jimenez
- 1-21 Spatiotemporal transcriptome and metabolome landscapes of cotton somatic embryos
by Xiaoyang Ge & Xiaole Yu & Zhixin Liu & Jiachen Yuan & Aizhi Qin & Ye Wang & Yanli Chen & Wenqiang Qin & Yumeng Liu & Xingxing Liu & Yaping Zhou & Peng Wang & Jincheng Yang & Hao Liu & Zihao Zhao & Mengke Hu & Yixin Zhang & Susu Sun & Luis Herrera-Estrella & Lam-Son Phan Tran & Xuwu Sun & Fuguang Li
- 1-21 Radial glia integrin avb8 regulates cell autonomous microglial TGFβ1 signaling that is necessary for microglial identity
by Gabriel L. McKinsey & Nicolas Santander & Xiaoming Zhang & Kilian L. Kleemann & Lauren Tran & Aditya Katewa & Kaylynn Conant & Matthew Barraza & Kian Waddell & Carlos O. Lizama & Marie La Russa & Ji Hyun Koo & Hyunji Lee & Dibyanti Mukherjee & Helena Paidassi & E. S. Anton & Kamran Atabai & Dean Sheppard & Oleg Butovsky & Thomas D. Arnold
- 1-21 Cleavage of CAD by caspase-3 determines the cancer cell fate during chemotherapy
by Jingsong Ma & Jiabao Zhao & Chensong Zhang & Jinshui Tan & Ao Cheng & Zhuo Niu & Zeyang Lin & Guangchao Pan & Chao Chen & Yang Ding & Mengya Zhong & Yifan Zhuang & Yubo Xiong & Huiwen Zhou & Shengyi Zhou & Meijuan Xu & Wenjie Ye & Funan Li & Yongxi Song & Zhenning Wang & Xuehui Hong
- 1-21 Systematic analysis of cotranscriptional RNA folding using transcription elongation complex display
by Skyler L. Kelly & Eric J. Strobel
- 1-21 Worm Perturb-Seq: massively parallel whole-animal RNAi and RNA-seq
by Hefei Zhang & Xuhang Li & Dongyuan Song & Onur Yukselen & Shivani Nanda & Alper Kucukural & Jingyi Jessica Li & Manuel Garber & Albertha J. M. Walhout
- 1-21 VSTM2L protects prostate cancer cells against ferroptosis via inhibiting VDAC1 oligomerization and maintaining mitochondria homeostasis
by Juan Yang & Xiao Lu & Jing-Lan Hao & Lan Li & Yong-Tong Ruan & Xue-Ni An & Qi-Lai Huang & Xiao-Ming Dong & Ping Gao
- 1-21 The impact of a high fat diet and platelet activation on pre-metastatic niche formation
by Marta Hergueta-Redondo & Sara Sánchez-Redondo & Begoña Hurtado & Vanesa Santos & Manuel Pérez-Martínez & Pilar Ximénez- Embún & Sheri A. C. McDowell & Marina S. Mazariegos & Gadea Mata & Raúl Torres-Ruiz & Sandra Rodríguez-Perales & Lola Martínez & Osvaldo Graña-Castro & Diego Megias & Daniela Quail & Miguel Quintela-Fandino & Héctor Peinado
- 1-21 Transcriptional and epigenetic rewiring by the NUP98::KDM5A fusion oncoprotein directly activates CDK12
by Selina Troester & Thomas Eder & Nadja Wukowits & Martin Piontek & Pablo Fernández-Pernas & Johannes Schmoellerl & Ben Haladik & Gabriele Manhart & Melanie Allram & Margarita Maurer-Granofszky & Nastassja Scheidegger & Karin Nebral & Giulio Superti-Furga & Roland Meisel & Beat Bornhauser & Peter Valent & Michael N. Dworzak & Johannes Zuber & Kaan Boztug & Florian Grebien
- 1-21 ETVs dictate hPSC differentiation by tuning biophysical properties
by Natalia M. Ziojła & Magdalena Socha & M. Cecilia Guerra & Dorota Kizewska & Katarzyna Blaszczyk & Edyta Urbaniak & Sara Henry & Malgorzata Grabowska & Kathy K. Niakan & Aryeh Warmflash & Malgorzata Borowiak
- 1-21 Discrete vulnerability to pharmacological CDK2 inhibition is governed by heterogeneity of the cancer cell cycle
by Vishnu Kumarasamy & Jianxin Wang & Michelle Roti & Yin Wan & Adam P. Dommer & Hanna Rosenheck & Sivasankar Putta & Alec Trub & John Bisi & Jay Strum & Patrick Roberts & Seth M. Rubin & Costakis Frangou & Karen McLean & Agnieszka K. Witkiewicz & Erik S. Knudsen
- 1-21 Identification and characterization of cell niches in tissue from spatial omics data at single-cell resolution
by Jingyang Qian & Xin Shao & Hudong Bao & Yin Fang & Wenbo Guo & Chengyu Li & Anyao Li & Hua Hua & Xiaohui Fan
- 1-21 GLP-1R/GCGR dual agonism dissipates hepatic steatosis to restore insulin sensitivity and rescue pancreatic β-cell function in obese male mice
by Rhianna C. Laker & Shaun Egolf & Sarah Will & Louise Lantier & Owen P. McGuinness & Charles Brown & Nicholas Bhagroo & Stephanie Oldham & Kyle Kuszpit & Alex Alfaro & Xidan Li & Taewook Kang & Giovanni Pellegrini & Anne-Christine Andréasson & Sarina Kajani & Sadichha Sitaula & Martin R. Larsen & Christopher J. Rhodes
- 1-21 Dynamic coding and sequential integration of multiple reward attributes by primate amygdala neurons
by Fabian Grabenhorst & Raymundo Báez-Mendoza
- 1-21 The spatiotemporal transcriptional profiling of murine brain during cerebral malaria progression and after artemisinin treatment
by Jiayun Chen & Yunmeng Bai & Xueling He & Wei Xiao & Lina Chen & Yin Kwan Wong & Chen Wang & Peng Gao & Guangqing Cheng & Liting Xu & Chuanbin Yang & Fulong Liao & Guang Han & Jichao Sun & Chengchao Xu & Jigang Wang
- 1-21 Wnt signalosome assembly is governed by conformational flexibility of Axin and by the AP2 clathrin adaptor
by Melissa V. Gammons & Elsa Franco-Echevarría & Tie-Mei Li & Trevor J. Rutherford & Miha Renko & Christopher Batters & Mariann Bienz
- 1-21 Spatial transcriptomics of the aging mouse brain reveals origins of inflammation in the white matter
by Lin Wang & Chang-Yi Cui & Christopher T. Lee & Monica Bodogai & Na Yang & Changyou Shi & Mustafa O. Irfanoglu & James R. Occean & Sadia Afrin & Nishat Sarker & Ross A. McDevitt & Elin Lehrmann & Shahroze Abbas & Nirad Banskota & Jinshui Fan & Supriyo De & Peter Rapp & Arya Biragyn & Dan Benjamini & Manolis Maragkakis & Payel Sen
- 1-21 Alternative splicing across the C. elegans nervous system
by Alexis Weinreb & Erdem Varol & Alec Barrett & Rebecca M. McWhirter & Seth R. Taylor & Isabel Courtney & Manasa Basavaraju & Abigail Poff & John A. Tipps & Becca Collings & Smita Krishnaswamy & David M. Miller & Marc Hammarlund
- 1-21 Neural circuits underlying context-dependent competition between defensive actions in Drosophila larvae
by Maxime Lehman & Chloé Barré & Md Amit Hasan & Benjamin Flament & Sandra Autran & Neena Dhiman & Peter Soba & Jean-Baptiste Masson & Tihana Jovanic
- 1-21 Mapping the interaction surface between CaVβ and actin and its role in calcium channel clearance
by Francisco Castilla & Victor Lugo & Erick Miranda-Laferte & Nadine Jordan & Pitter F. Huesgen & Beatrix Santiago-Schübel & Mercedes Alfonso-Prieto & Patricia Hidalgo
- 1-21 Mapping variants in thyroid hormone transporter MCT8 to disease severity by genomic, phenotypic, functional, structural and deep learning integration
by Stefan Groeneweg & Ferdy S. Geest & Mariano Martín & Mafalda Dias & Jonathan Frazer & Carolina Medina-Gomez & Rosalie B. T. M. Sterenborg & Hao Wang & Anna Dolcetta-Capuzzo & Linda J. Rooij & Alexander Teumer & Ayhan Abaci & Erica L. T. Akker & Gautam P. Ambegaonkar & Christine M. Armour & Iiuliu Bacos & Priyanka Bakhtiani & Diana Barca & Andrew J. Bauer & Sjoerd A. A. Berg & Amanda Berge & Enrico Bertini & Ingrid M. Beynum & Nicola Brunetti-Pierri & Doris Brunner & Marco Cappa & Gerarda Cappuccio & Barbara Castellotti & Claudia Castiglioni & Krishna Chatterjee & Alexander Chesover & Peter Christian & Jet Coenen-van der Spek & Irenaeus F. M. Coo & Regis Coutant & Dana Craiu & Patricia Crock & Christian DeGoede & Korcan Demir & Cheyenne Dewey & Alice Dica & Paul Dimitri & Marjolein H. G. Dremmen & Rachana Dubey & Anina Enderli & Jan Fairchild & Jonathan Gallichan & Luigi Garibaldi & Belinda George & Evelien F. Gevers & Erin Greenup & Annette Hackenberg & Zita Halász & Bianka Heinrich & Anna C. Hurst & Tony Huynh & Amber R. Isaza & Anna Klosowska & Marieke M. Knoop & Daniel Konrad & David A. Koolen & Heiko Krude & Abhishek Kulkarni & Alexander Laemmle & Stephen H. LaFranchi & Amy Lawson-Yuen & Jan Lebl & Selmar Leeuwenburgh & Michaela Linder-Lucht & Anna López Martí & Cláudia F. Lorea & Charles M. Lourenço & Roelineke J. Lunsing & Greta Lyons & Jana Krenek Malikova & Edna E. Mancilla & Kenneth L. McCormick & Anne McGowan & Veronica Mericq & Felipe Monti Lora & Carla Moran & Katalin E. Muller & Lindsey E. Nicol & Isabelle Oliver-Petit & Laura Paone & Praveen G. Paul & Michel Polak & Francesco Porta & Fabiano O. Poswar & Christina Reinauer & Klara Rozenkova & Rowen Seckold & Tuba Seven Menevse & Peter Simm & Anna Simon & Yogen Singh & Marco Spada & Milou A. M. Stals & Merel T. Stegenga & Athanasia Stoupa & Gopinath M. Subramanian & Lilla Szeifert & Davide Tonduti & Serap Turan & Joel Vanderniet & Adri Walt & Jean-Louis Wémeau & Anne-Marie Wermeskerken & Jolanta Wierzba & Marie-Claire Y. Wit & Nicole I. Wolf & Michael Wurm & Federica Zibordi & Amnon Zung & Nitash Zwaveling-Soonawala & Fernando Rivadeneira & Marcel E. Meima & Debora S. Marks & Juan P. Nicola & Chi-Hua Chen & Marco Medici & W. Edward Visser
- 1-21 A highly conserved neuronal microexon in DAAM1 controls actin dynamics, RHOA/ROCK signaling, and memory formation
by Patryk Poliński & Marta Miret Cuesta & Alfonsa Zamora-Moratalla & Federica Mantica & Gerard Cantero-Recasens & Carlotta Viana & Miguel Sabariego-Navarro & Davide Normanno & Luis P. Iñiguez & Cruz Morenilla-Palao & Patricia Ordoño & Sophie Bonnal & Jonathan D. Ellis & Raúl Gómez-Riera & Hugo Fanlo-Ucar & Dominic S. Yap & María Martínez De Lagrán & Álvaro Fernández-Blanco & Cristina Rodríguez-Marin & Jon Permanyer & Orsolya Fölsz & Eduardo Dominguez-Sala & Cesar Sierra & Diana Legutko & José Wojnacki & Juan Luis Musoles Lleo & Maria Pia Cosma & Francisco José Muñoz & Benjamin J. Blencowe & Eloisa Herrera & Mara Dierssen & Manuel Irimia
- 1-21 Ultrafast fMRI reveals serial queuing of information processing during multitasking in the human brain
by Qiuhai Yue & Allen T. Newton & René Marois
- 1-21 Targeting the ceramidase ACER3 attenuates cholestasis in mice by mitigating bile acid overload via unsaturated ceramide-mediated LXRβ signaling transduction
by Leyi Liao & Ziying Liu & Lei Liu & Can Huang & Yiyi Li & Cungui Mao & Ruijuan Xu & Haiqing Liu & Cuiting Liu & Yonghong Peng & Tingying Lei & Hanbiao Liang & Sheng Yu & Jianping Qian & Xianqiu Wu & Biao Wang & Yixiong Lin & Jie Zhou & Qingping Li & Chuanjiang Li & Kai Wang
- 1-21 Biomimetic culture substrates for modelling homeostatic intestinal epithelium in vitro
by Sorosh Abdollahi & Bahareh Zarin & Maryam Vatani & Fereshteh Vajhadin & Mohsen Hassani & Pezhman Jalali & Keekyoung Kim & Amir Sanati-Nezhad
- 1-21 Metabolic reprogramming driven by Ant2 deficiency augments T Cell function and anti-tumor immunity in mice
by Omri Yosef & Leonor Cohen-Daniel & Oded Shamriz & Zahala Bar-On & Wajeeh Salaymeh & Amijai Saragovi & Ifat Abramovich & Bella Agranovich & Veronika Lutz & Joseph Tam & Anna Permyakova & Eyal Gottlieb & Magdalena Huber & Michael Berger
- 1-21 Molecular basis of foreign DNA recognition by BREX anti-phage immunity system
by Alena Drobiazko & Myfanwy C. Adams & Mikhail Skutel & Kristina Potekhina & Oksana Kotovskaya & Anna Trofimova & Mikhail Matlashov & Daria Yatselenko & Karen L. Maxwell & Tim R. Blower & Konstantin Severinov & Dmitry Ghilarov & Artem Isaev
- 1-21 Sub-cellular population imaging tools reveal stable apical dendrites in hippocampal area CA3
by Jason J. Moore & Shannon K. Rashid & Emmett Bicker & Cara D. Johnson & Naomi Codrington & Dmitri B. Chklovskii & Jayeeta Basu
- 1-21 Structural recognition and stabilization of tyrosine hydroxylase by the J-domain protein DNAJC12
by Mary Dayne S. Tai & Lissette Ochoa & Marte I. Flydal & Lorea Velasco-Carneros & Jimena Muntaner & César Santiago & Gloria Gamiz-Arco & Fernando Moro & Kunwar Jung-KC & David Gil-Cantero & Miguel Marcilla & Juha P. Kallio & Arturo Muga & José María Valpuesta & Jorge Cuéllar & Aurora Martinez
- 1-21 An integrative systems-biology approach defines mechanisms of Alzheimer’s disease neurodegeneration
by Matthew J. Leventhal & Camila A. Zanella & Byunguk Kang & Jiajie Peng & David Gritsch & Zhixiang Liao & Hassan Bukhari & Tao Wang & Ping-Chieh Pao & Serwah Danquah & Joseph Benetatos & Ralda Nehme & Samouil Farhi & Li-Huei Tsai & Xianjun Dong & Clemens R. Scherzer & Mel B. Feany & Ernest Fraenkel
- 1-21 Fucosylated haptoglobin promotes inflammation via Mincle in sepsis: an observational study
by Taylor Roh & Sungeun Ju & So Young Park & Yeonghwan Ahn & Jiyun Chung & Miyako Nakano & Gyoungah Ryu & Young Jae Kim & Geumseo Kim & Hyewon Choi & Sung-Gwon Lee & In Soo Kim & Song-I Lee & Chaeuk Chung & Takashi Shimizu & Eiji Miyoshi & Sung-Soo Jung & Chungoo Park & Sho Yamasaki & Seung-Yeol Park & Eun-Kyeong Jo
- 1-21 Patterns and drivers of diatom diversity and abundance in the global ocean
by Juan J. Pierella Karlusich & Karen Cosnier & Lucie Zinger & Nicolas Henry & Charlotte Nef & Guillaume Bernard & Eleonora Scalco & Etienne Dvorak & Fabio Rocha Jimenez Vieira & Erwan Delage & Samuel Chaffron & Sergey Ovchinnikov & Adriana Zingone & Chris Bowler
- 1-21 Epigenetic mechanisms controlling human leukemia stem cells and therapy resistance
by Sumiko Takao & Victor Morell & Masahiro Uni & Alicia Slavit & Sophia Rha & Shuyuan Cheng & Laura K. Schmalbrock & Fiona C. Brown & Sergi Beneyto-Calabuig & Richard P. Koche & Lars Velten & Alex Kentsis
- 1-21 Comprehensive evaluation of phosphoproteomic-based kinase activity inference
by Sophia Müller-Dott & Eric J. Jaehnig & Khoi Pham Munchic & Wen Jiang & Tomer M. Yaron-Barir & Sara R. Savage & Martin Garrido-Rodriguez & Jared L. Johnson & Alessandro Lussana & Evangelia Petsalaki & Jonathan T. Lei & Aurelien Dugourd & Karsten Krug & Lewis C. Cantley & D. R. Mani & Bing Zhang & Julio Saez-Rodriguez
- 1-21 Pan-inhibition of super-enhancer-driven oncogenic transcription by next-generation synthetic ecteinascidins yields potent anti-cancer activity
by Max Cigrang & Julian Obid & Maguelone Nogaret & Léane Seno & Tao Ye & Guillaume Davidson & Philippe Catez & Pietro Berico & Clara Capelli & Clara Marechal & Amélie Zachayus & Clémence Elly & Marie Jose Guillen Navarro & Marta Martinez Diez & Gema Santamaria Nunez & Tsai-Kun Li & Emmanuel Compe & Pablo Avilés & Irwin Davidson & Jean-Marc Egly & Carmen Cuevas & Frédéric Coin
- 1-21 Mitochondrial damage in muscle specific PolG mutant mice activates the integrated stress response and disrupts the mitochondrial folate cycle
by Simon T. Bond & Emily J. King & Shannen M. Walker & Christine Yang & Yingying Liu & Kevin H. Liu & Aowen Zhuang & Aaron W. Jurrjens & Haoyun A. Fang & Luke E. Formosa & Artika P. Nath & Sergio Ruiz Carmona & Michael Inouye & Thy Duong & Kevin Huynh & Peter J. Meikle & Simon Crawford & Georg Ramm & Sheik Nadeem Elahee Doomun & David P. Souza & Danielle L. Rudler & Anna C. Calkin & Aleksandra Filipovska & David W. Greening & Darren C. Henstridge & Brian G. Drew
- 1-21 Phosphorylation-dependent WRN-RPA interaction promotes recovery of stalled forks at secondary DNA structure
by Alessandro Noto & Pasquale Valenzisi & Flavia Feo & Federica Fratini & Tomasz Kulikowicz & Joshua A. Sommers & Benedetta Perdichizzi & Maurizio Semproni & Valentina Palermo & Marco Crescenzi & Robert M. Brosh Jr & Annapaola Franchitto & Pietro Pichierri
- 1-21 Multiplexed subspaces route neural activity across brain-wide networks
by Camden J. MacDowell & Alexandra Libby & Caroline I. Jahn & Sina Tafazoli & Adel Ardalan & Timothy J. Buschman
- 1-21 Taming large-scale genomic analyses via sparsified genomics
by Mohammed Alser & Julien Eudine & Onur Mutlu
- 1-21 Muscle fiber Myc is dispensable for muscle growth and its forced expression severely perturbs homeostasis
by Daniel J. Ham & Michelangelo Semeraro & Bianca M. Berger & Timothy J. McGowan & Shuo Lin & Eleonora Maino & Filippo Oliveri & Markus A. Rüegg
- 1-21 Caspase-11 drives macrophage hyperinflammation in models of Polg-related mitochondrial disease
by Jordyn J. VanPortfliet & Yuanjiu Lei & Muthumeena Ramanathan & Camila Guerra Martinez & Jessica Wong & Tim J. Stodola & Brian R. Hoffmann & Kathryn Pflug & Raquel Sitcheran & Stephen C. Kneeland & Stephen A. Murray & Peter. J. McGuire & Carolyn L. Cannon & A. Phillip West
- 1-21 The deubiquitylating enzyme Fat facets promotes Fat signalling and restricts tissue growth
by Lauren E. Dawson & Aashika Sekar & Alexander D. Fulford & Rachel I. Lambert & Hannah S. Burgess & Paulo S. Ribeiro
- 1-21 Cell Painting PLUS: expanding the multiplexing capacity of Cell Painting-based phenotypic profiling using iterative staining-elution cycles
by Elena Coburg & Marlene Wedler & Jose M. Muino & Christopher Wolff & Nils Körber & Sebastian Dunst & Shu Liu
- 1-21 Pathogenic mutation impairs functional dynamics of Hsp60 in mono- and oligomeric states
by Luca Torielli & Federica Guarra & Hao Shao & Jason E. Gestwicki & Stefano A. Serapian & Giorgio Colombo
- 1-21 Cross-talks between Metabolic and Translational Controls during Beige Adipocyte Differentiation
by Daehwa Youn & Boseon Kim & Dahee Jeong & Ju Yeon Lee & Seha Kim & Dulguun Sumberzul & Rehna Paula Ginting & Min-Woo Lee & Ju Hwan Song & Ye Seul Park & Yumin Kim & Chang-Myung Oh & Mihye Lee & Jun Cho
- 1-21 Resonant inelastic X-ray scattering tools to count 5 f electrons of actinides and probe bond covalency
by Bianca Schacherl & Michelangelo Tagliavini & Hanna Kaufmann-Heimeshoff & Jörg Göttlicher & Marinella Mazzanti & Karin Popa & Olaf Walter & Tim Pruessmann & Christian Vollmer & Aaron Beck & Ruwini S. K. Ekanayake & Jacob A. Branson & Thomas Neill & David Fellhauer & Cedric Reitz & Dieter Schild & Dominique Brager & Christopher Cahill & Cory Windorff & Thomas Sittel & Harry Ramanantoanina & Maurits W. Haverkort & Tonya Vitova
- 1-21 Programmed enhancement of endogenous iron-mediated lysosomal membrane permeabilization for tumor ferroptosis/pyroptosis dual-induction
by Luwen Zhu & Jiahao Hu & Xiaochuan Wu & Jucong Zhang & Xinyi Xu & Xiajie Huang & Bing Tian & Chun-Xia Zhao & Yongzhong Du & Liming Wu
- 1-21 Early-life gut microbiome associates with positive vaccine take and shedding in neonatal schedule of the human neonatal rotavirus vaccine RV3-BB
by Josef Wagner & Amanda Handley & Celeste M. Donato & Eleanor A. Lyons & Daniel Pavlic & Darren Suryawijaya Ong & Rhian Bonnici & Nada Bogdanovic-Sakran & Edward P. K. Parker & Christina Bronowski & Jarir At Thobari & Cahya Dewi Satria & Hera Nirwati & Desiree Witte & Khuzwayo C. Jere & Ashley Mpakiza & Emma Watts & Ann Turner & Karen Boniface & Jonathan Mandolo & Frances Justice & Naor Bar-Zeev & Miren Iturriza-Gomara & Jim P. Buttery & Nigel A. Cunliffe & Yati Soenarto & Julie E. Bines
- 1-21 Locomotion-dependent auditory gating to the parietal cortex guides multisensory decisions
by Ilsong Choi & Seung-Hee Lee
- 1-21 CREBBP inactivation sensitizes B cell acute lymphoblastic leukemia to ferroptotic cell death upon BCL2 inhibition
by Alicia Garcia-Gimenez & Jonathan E. Ditcham & Dhoyazan M. A. Azazi & George Giotopoulos & Ryan Asby & Eshwar Meduri & Jaana Bagri & Nathalie Sakakini & Cecile K. Lopez & Nisha Narayan & Tumas Beinortas & Shuchi Agrawal-Singh & Kent Fung & David O’Connor & Marc R. Mansour & Husam B. R. Alabed & Benjamin Jenkins & Albert Koulman & Michael P. Murphy & Sarah J. Horton & Brian J. P. Huntly & Simon E. Richardson
- 1-21 Antisense oligonucleotide-mediated TRA2β poison exon inclusion induces the expression of a lncRNA with anti-tumor effects
by Nathan K. Leclair & Mattia Brugiolo & SungHee Park & Maeva Devoucoux & Laura Urbanski & Brittany L. Angarola & Marina Yurieva & Olga Anczuków
- 1-21 Intercellular bridges are essential for transposon repression and meiosis in the male germline
by Julia Sorkin & Kevin Tilton & Matthew A. Lawlor & Shreya N. Sarathy & Shun Liang & Angelina Albanese & Mashiat Rabbani & Saher S. Hammoud & Christopher E. Ellison & Florencia Pratto & Devanshi Jain
- 1-21 AIF3 splicing variant elicits mitochondrial malfunction via the concurrent dysregulation of electron transport chain and glutathione-redox homeostasis
by Mi Zhou & Shuiqiao Liu & Yanan Wang & Bo Zhang & Ming Zhu & Jennifer E. Wang & Veena Rajaram & Yisheng Fang & Weibo Luo & Yingfei Wang
- 1-21 Long-read sequencing of 945 Han individuals identifies structural variants associated with phenotypic diversity and disease susceptibility
by Jiao Gong & Huiru Sun & Kaiyuan Wang & Yanhui Zhao & Yechao Huang & Qinsheng Chen & Hui Qiao & Yang Gao & Jialin Zhao & Yunchao Ling & Ruifang Cao & Jingze Tan & Qi Wang & Yanyun Ma & Jing Li & Jingchun Luo & Sijia Wang & Jiucun Wang & Guoqing Zhang & Shuhua Xu & Feng Qian & Fang Zhou & Huiru Tang & Dali Li & Fritz J. Sedlazeck & Li Jin & Yuting Guan & Shaohua Fan
- 1-21 Combined targeting of glioblastoma stem cells of different cellular states disrupts malignant progression
by Chenfei Lu & Tao Kang & Junxia Zhang & Kailin Yang & Yang Liu & Kefan Song & Qiankun Lin & Deobrat Dixit & Ryan C. Gimple & Qian Zhang & Zhumei Shi & Xiao Fan & Qiulian Wu & Daqi Li & Danyang Shan & Jiancheng Gao & Danling Gu & Hao You & Yangqing Li & Junlei Yang & Linjie Zhao & Zhixin Qiu & Hui Yang & Ningwei Zhao & Wei Gao & Weiwei Tao & Yingmei Lu & Yun Chen & Jing Ji & Zhe Zhu & Chunsheng Kang & Jianghong Man & Sameer Agnihotri & Qianghu Wang & Fan Lin & Xu Qian & Stephen C. Mack & Zhibin Hu & Chaojun Li & Michael D. Taylor & Ning Liu & Nu Zhang & Ming Lu & Yongping You & Jeremy N. Rich & Wei Zhang & Xiuxing Wang
- 1-21 Chiral polypeptide hydrogels regulating local immune microenvironment and anti-tumor immune response
by Junfeng Ding & Tianran Wang & Zhiqiang Lin & Zhenyu Li & Jiaxuan Yang & Fujiang Li & Yan Rong & Xuesi Chen & Chaoliang He
- 1-21 An individual-based modelling study estimating the impact of maternity service delivery on health in Malawi
by Joseph H. Collins & Helen Allott & Wingston Ng’ambi & Ines Li Lin & Mosè Giordano & Matthew M. Graham & Eva Janoušková & Fannie Kachale & Kondwani Kawaza & Tara D. Mangal & Joseph Mfutso-Bengo & Emmanuel Mnjowe & Sakshi Mohan & Margherita Molaro & Dominic Nkhoma & Paul Revill & Alison Rodger & Bingling She & Asif U. Tamuri & Cally J. Tann & Pakwanja D. Twea & Valentina Cambiano & Timothy B. Hallett & Andrew N. Phillips & Tim Colbourn
- 1-21 PPARα-mediated lipid metabolism reprogramming supports anti-EGFR therapy resistance in head and neck squamous cell carcinoma
by Valentin Van den bossche & Julie Vignau & Engy Vigneron & Isabella Rizzi & Hannah Zaryouh & An Wouters & Jérôme Ambroise & Steven Van Laere & Simon Beyaert & Raphaël Helaers & Cédric van Marcke & Lionel Mignion & Elise Y. Lepicard & Bénédicte F. Jordan & Céline Guilbaud & Olivier Lowyck & Hajar Dahou & Antonella Mendola & Manon Desgres & Léo Aubert & Isabelle Gerin & Guido T. Bommer & Romain Boidot & Perrine Vermonden & Aurélien Warnant & Yvan Larondelle & Jean-Pascal Machiels & Olivier Feron & Sandra Schmitz & Cyril Corbet
- 1-21 An oligodendrocyte silencer element underlies the pathogenic impact of lamin B1 structural variants
by Bruce Nmezi & Guillermo Rodriguez Bey & Talia DeFrancesco Oranburg & Kseniia Dudnyk & Santana M. Lardo & Nathan Herdman & Anastasia Jacko & Sandy Rubio & Emanuel Loeza-Alcocer & Julia Kofler & Dongkyeong Kim & Julia Rankin & Emma Kivuva & Nicholas Gutowski & Katherine Schon & Jelle Ameele & Patrick F. Chinnery & Sérgio B. Sousa & Filipe Palavra & Camilo Toro & Filippo Pinto e Vairo & Jonas Saute & Lisa Pan & Murad Alturkustani & Robert Hammond & Francois Gros-Louis & Michael S. Gold & Yungki Park & Geneviève Bernard & Raili Raininko & Jian Zhou & Sarah J. Hainer & Quasar S. Padiath
- 1-21 Optogenetic activation of mechanical nociceptions to enhance implant osseointegration
by Qijin Wang & Yang Chen & Haiqi Ding & Yuanqing Cai & Xuhui Yuan & Jianhua Lv & Jiagu Huang & Jiexin Huang & Chaofan Zhang & Zihao Hong & Hongyan Li & Ying Huang & Jiamin Lin & Lin Yuan & Lan Lin & Shaolin Yu & Canhong Zhang & Jianhua Lin & Wenbo Li & Cheng Chang & Bin Yang & Wenming Zhang & Xinyu Fang
- 1-21 Inhibition of MBTPS1 enhances antitumor immunity and potentiates anti-PD-1 immunotherapy
by Yi-Yu Wang & Jin-Fei Lin & Wen-Wei Wu & Zhe Fu & Fen Cao & Yan-Xing Chen & Hai-Yu Mo & Hui Sheng & Ze-Xian Liu & Zhao-Lei Zeng & Xin-Yuan Guan & Huai-Qiang Ju & Kun Liao & Rui-Hua Xu
- 1-21 Tipping point-induced abrupt shifts in East Asian hydroclimate since the Last Glacial Maximum
by Fuzhi Lu & Huayu Lu & Yao Gu & Pengyu Lin & Zhengyao Lu & Qiong Zhang & Hongyan Zhang & Fan Yang & Xiaoyi Dong & Shuangwen Yi & Deliang Chen & Francesco S. R. Pausata & Maya Ben-Yami & Jennifer V. Mecking
- 1-21 Serpina3k lactylation protects from cardiac ischemia reperfusion injury
by Le Wang & Dandan Li & Fang Yao & Shanshan Feng & Chao Tong & Rongjia Rao & Meiyan Zhong & Xianqiang Wang & Wei Feng & Zhan Hu & Bo Jin & Li Wang & Shengshou Hu & Bingying Zhou
- 1-21 Myeloid lineage C3 induces reactive gliosis and neuronal stress during CNS inflammation
by Thomas Garton & Matthew D. Smith & Ajay Kesharwani & Marjan Gharagozloo & Sungtaek Oh & Chan-Hyun Na & Martina Absinta & Daniel S. Reich & Donald J. Zack & Peter A. Calabresi
- 1-21 Food and water intake are regulated by distinct central amygdala circuits revealed using intersectional genetics
by Federica Fermani & Simon Chang & Ylenia Mastrodicasa & Christian Peters & Louise Gaitanos & Pilar L. Alcala Morales & Charu Ramakrishnan & Karl Deisseroth & Rüdiger Klein
- 1-21 Dissecting apicoplast functions through continuous cultivation of Toxoplasma gondii devoid of the organelle
by Min Chen & Szilamér Gyula Koszti & Alessandro Bonavoglia & Bohumil Maco & Olivier Rohr & Hong-Juan Peng & Dominique Soldati-Favre & Joachim Kloehn
- 1-21 Expression of foetal gene Pontin is essential in protecting heart against pathological remodelling and cardiomyopathy
by Bayu Lestari & Ardiansah Bayu Nugroho & Thuy Anh Bui & Binh Nguyen & Nicholas Stafford & Sukhpal Prehar & Min Zi & Ryan Potter & Efta Triastuti & Florence M. Baudoin & Alicia D’Souza & Xin Wang & Elizabeth J. Cartwright & Delvac Oceandy
- 1-21 FLT1 and other candidate fetal haemoglobin modifying loci in sickle cell disease in African ancestries
by Ambroise Wonkam & Kevin Esoh & Rachel M. Levine & Valentina Josiane Ngo Bitoungui & Khuthala Mnika & Nikitha Nimmagadda & Erin A. D. Dempsey & Siana Nkya & Raphael Z. Sangeda & Victoria Nembaware & Jack Morrice & Fujr Osman & Michael A. Beer & Julie Makani & Nicola Mulder & Guillaume Lettre & Martin H. Steinberg & Rachel Latanich & James F. Casella & Daiana Drehmer & Dan E. Arking & Emile R. Chimusa & Jonathan S. Yen & Gregory A. Newby & Stylianos E. Antonarakis
- 1-21 Reconstitution of human DNA licensing and the structural and functional analysis of key intermediates
by Jennifer N. Wells & Lucy V. Edwardes & Vera Leber & Shenaz Allyjaun & Matthew Peach & Joshua Tomkins & Antonia Kefala-Stavridi & Sarah V. Faull & Ricardo Aramayo & Carolina M. Pestana & Lepakshi Ranjha & Christian Speck
- 1-21 Myristoylated Eepd1 Enhances Lipolysis and Thermogenesis through PKA Activation to Combat Obesity
by Suzhen Chen & Yanping Wang & Qian Zhou & Qiqi Qian & Quanxin Jiang & Chuchu Liu & Yan Liu & Peihui Zhou & Jie Xiong & Yao Zhang & Ning Wang & Yang Emma Li & Limin Yin & Hongyuan Yang & Junli Liu
- 1-21 FGF21 protects against HFpEF by improving cardiac mitochondrial bioenergetics in mice
by Ke Zhang & Jing Gan & Baile Wang & Wei Lei & Dong Zhen & Jie Yang & Ningrui Wang & Congcong Wen & Xiaotang Gao & Xiaokun Li & Aimin Xu & Xinguang Liu & Yulin Li & Fan Wu & Zhuofeng Lin
- 1-21 Microglial NLRP3-gasdermin D activation impairs blood-brain barrier integrity through interleukin-1β-independent neutrophil chemotaxis upon peripheral inflammation in mice
by Sung-Hyun Yoon & Chae youn Kim & Eunju Lee & Changjun Lee & Kyung-Seo Lee & Jaeho Lee & Hana Park & Bokeum Choi & Inhwa Hwang & Junhan Kim & Tae-Gyun Kim & Junghyun Son & Young-Min Hyun & Seunghee Hong & Je-Wook Yu
- 1-21 IL-1 protects from fatal systemic candidiasis in mice by inhibiting oxidative phosphorylation and hypoxia
by Sofia Horn & Mareike Schmid & Ivan Berest & Federica Piattini & Jing Zhang & Katrien de Bock & Olivier Devuyst & Stellor Nlandu Khodo & Jan Kisielow & Manfred Kopf
- 1-21 Efficient and accurate framework for genome-wide gene-environment interaction analysis in large-scale biobanks
by Yuzhuo Ma & Yanlong Zhao & Ji-Feng Zhang & Wenjian Bi
- 1-21 Single-cell analysis identifies the CNP/GC-B/cGMP axis as marker and regulator of modulated VSMCs in atherosclerosis
by Moritz Lehners & Hannes Schmidt & Maria T. K. Zaldivia & Daniel Stehle & Michael Krämer & Andreas Peter & Julia Adler & Robert Lukowski & Susanne Feil & Robert Feil
- 1-21 Systematic inference of super-resolution cell spatial profiles from histology images
by Peng Zhang & Chaofei Gao & Zhuoyu Zhang & Zhiyuan Yuan & Qian Zhang & Ping Zhang & Shiyu Du & Weixun Zhou & Yan Li & Shao Li
- 1-21 Dynamic allostery in the peptide/MHC complex enables TCR neoantigen selectivity
by Jiaqi Ma & Cory M. Ayres & Chad A. Brambley & Smita S. Chandran & Tatiana J. Rosales & W. W. J. Gihan Perera & Bassant Eldaly & William T. Murray & Steven A. Corcelli & Evgenii L. Kovrigin & Christopher A. Klebanoff & Brian M. Baker
- 1-21 Polymer model integrates imaging and sequencing to reveal how nanoscale heterochromatin domains influence gene expression
by Vinayak Vinayak & Ramin Basir & Rosela Golloshi & Joshua Toth & Lucas Sant’Anna & Melike Lakadamyali & Rachel Patton McCord & Vivek B. Shenoy
- 1-21 Mitofusin 2 displays fusion-independent roles in proteostasis surveillance
by Mariana Joaquim & Selver Altin & Maria-Bianca Bulimaga & Tânia Simões & Hendrik Nolte & Verian Bader & Camilla Aurora Franchino & Solenn Plouzennec & Karolina Szczepanowska & Elena Marchesan & Kay Hofmann & Marcus Krüger & Elena Ziviani & Aleksandra Trifunovic & Arnaud Chevrollier & Konstanze F. Winklhofer & Elisa Motori & Margarete Odenthal & Mafalda Escobar-Henriques
- 1-21 Microbial metabolites control self-renewal and precancerous progression of human cervical stem cells
by Jihyeon Myeong & Minho Lee & Bawool Lee & Joon Hyung Kim & Yeji Nam & Yeseul Choi & Jeongmin Kim & Se Young Jeon & Haewon Shim & Da-Ryung Jung & Youngjin Shin & Minsoo Jeong & Byungmoo Oh & Jaehun Jung & Christine S. Kim & Hyung Soo Han & Jae-Ho Shin & Yoon Hee Lee & Nora Jee-Young Park & Gun Oh Chong & Youngtae Jeong
- 1-21 IDH status dictates oHSV mediated metabolic reprogramming affecting anti-tumor immunity
by Upasana Sahu & Matthew P. Mullarkey & Sara A. Murphy & Joshua C. Anderson & Vasanta Putluri & Abu Hena Mostafa Kamal & Jun Hyoung Park & Tae Jin Lee & Alexander L. Ling & Benny A. Kaipparettu & Ashok Sharma & Nagireddy Putluri & Pamela L. Wenzel & Christopher D. Willey & E. Antonio Chiocca & James M. Markert & Balveen Kaur
- 1-21 Spatiotemporal transcriptome and metabolome landscapes of cotton fiber during initiation and early development
by Xuwu Sun & Aizhi Qin & Xingxing Wang & Xiaoyang Ge & Zhixin Liu & Chenxi Guo & Xiaole Yu & Xianliang Zhang & Yao Lu & Jincheng Yang & Jiuming He & Yaping Zhou & Yumeng Liu & Mengke Hu & Hao Liu & Zihao Zhao & Guanjing Hu & Wei Li & Xinshan Zang & Shuai Dai & Susu Sun & Lenin Yong-Villalobos & Luis Herrera-Estrella & Lam-Son Phan Tran & Xiongfeng Ma
- 1-21 Categorization of 34 computational methods to detect spatially variable genes from spatially resolved transcriptomics data
by Guanao Yan & Shuo Harper Hua & Jingyi Jessica Li
- 1-21 Chromosomal domain formation by archaeal SMC, a roadblock protein, and DNA structure
by Kodai Yamaura & Naomichi Takemata & Masashi Kariya & Ayami Osaka & Sonoko Ishino & Masataka Yamauchi & Tomonori Tamura & Itaru Hamachi & Shoji Takada & Yoshizumi Ishino & Haruyuki Atomi
- 1-21 Cooperation between the Hippo and MAPK pathway activation drives acquired resistance to TEAD inhibition
by Sayantanee Paul & Thijs J. Hagenbeek & Julien Tremblay & Vasumathi Kameswaran & Christy Ong & Chad Liu & Alissa D. Guarnaccia & James A. Mondo & Peter L. Hsu & Noelyn M. Kljavin & Bartosz Czech & Janina Smola & Dieu An H. Nguyen & Jennifer A. Lacap & Trang H. Pham & Yuxin Liang & Robert A. Blake & Luca Gerosa & Matthew Grimmer & Shiqi Xie & Bence Daniel & Xiaosai Yao & Anwesha Dey
- 1-21 Hepatic AKAP1 deficiency exacerbates diet-induced MASLD by enhancing GPAT1-mediated lysophosphatidic acid synthesis
by Linjie He & Xiaojuan She & Lifei Guo & Mingshu Gao & Shuangbin Wang & Zhenxing Lu & Haitao Guo & Renlong Li & Yongzhan Nie & Jinliang Xing & Lele Ji
- 1-21 Machine-learning meta-analysis reveals ethylene as a central component of the molecular core in abiotic stress responses in Arabidopsis
by Raul Sanchez-Munoz & Thomas Depaepe & Marketa Samalova & Jan Hejatko & Isiah Zaplana & Dominique Van Der Straeten
- 1-21 Effective extracellular payload release and immunomodulatory interactions govern the therapeutic effect of trastuzumab deruxtecan (T-DXd)
by Li-Chung Tsao & John S. Wang & Xingru Ma & Sirajbir Sodhi & Joey V. Ragusa & Bushangqing Liu & Jason McBane & Tao Wang & Junping Wei & Cong-Xiao Liu & Xiao Yang & Gangjun Lei & Ivan Spasojevic & Ping Fan & Timothy N. Trotter & Michael Morse & Herbert Kim Lyerly & Zachary C. Hartman
- 1-21 Lysosomal NKG7 restrains mTORC1 activity to promote CD8+ T cell durability and tumor control
by Hyoungjun Ham & Jacob B. Hirdler & Daniel T. Bihnam & Zhiming Mao & Joanina K. Gicobi & Bruna Gois Macedo & Maria F. Rodriguez-Quevedo & Destiny F. Schultz & Cristina Correia & Jun Zhong & Kodi E. Martinez & Alma Banuelos & Dallin S. Ashton & Anthony B. Lagnado & Ruifeng Guo & Rodrigo Pessoa & Akhilesh Pandey & Hu Li & Fabrice Lucien & Henrique Borges da Silva & Haidong Dong & Daniel D. Billadeau
- 1-21 E3 ubiquitin ligase RNF128 promotes Lys63-linked polyubiquitination on SRB1 in macrophages and aggravates atherosclerosis
by Yapeng Liu & Xinyu Zhang & Liwen Yu & Lei Cao & Jie Zhang & Qian Li & Xiaohong Wang & Wenqian Qi & Liangyu Cai & Ruiqing Ren & Weiwei Wang & Xiaobin Guo & Guohai Su & Bo Xi & Yun Zhang & Chengjiang Gao & Meng Zhang & Cheng Zhang
- 1-21 A supramolecular bactericidal material for preventing and treating plant-associated biofilms
by Jinghan Yang & Kongjun Liu & Yazhen Chen & Haojie Ye & Gefei Hao & Fengpei Du & Peiyi Wang
- 1-21 Symmetric adenine methylation is an essential DNA modification in the early-diverging fungus Rhizopus microsporus
by Carlos Lax & Stephen J. Mondo & José F. Martínez & Anna Muszewska & Leo A. Baumgart & José A. Pérez-Ruiz & Pablo Carrillo-Marín & Kurt LaButti & Anna Lipzen & Yu Zhang & Jie Guo & Vivian Ng & Eusebio Navarro & Teresa E. Pawlowska & Igor V. Grigoriev & Francisco E. Nicolás & Victoriano Garre
- 1-21 miR-142 deficit in T cells during blast crisis promotes chronic myeloid leukemia immune escape
by Fang Chen & Dandan Zhao & Yongfang Xu & Yi Zhang & Min-Hsuan Chen & Khyatiben V. Pathak & Nate Hansen & Brooke Lovell & Yong Liang & Katrina Estrella & Wei-Le Wang & Lucy Ghoda & Russell Rockne & Xiwei Wu & Haris Ali & Jianhua Yu & Michael A. Caligiuri & Stephen J. Forman & Jeff M. Trent & Ya-Huei Kuo & Ling Li & Piotr Swiderski & Jianying Zhang & Marcin Kortylewski & Le Xuan Truong Nguyen & Patrick Pirrotte & Mark Boldin & Guido Marcucci & Bin Zhang
- 1-21 The hypolipidemic effect of MI-883, the combined CAR agonist/ PXR antagonist, in diet-induced hypercholesterolemia model
by Jan Dusek & Ivana Mejdrová & Klára Dohnalová & Tomas Smutny & Karel Chalupsky & Maria Krutakova & Josef Skoda & Azam Rashidian & Ivona Pavkova & Kryštof Škach & Jana Hricová & Michaela Chocholouskova & Lucie Smutna & Rajamanikkam Kamaraj & Miloš Hroch & Martin Leníček & Stanislav Mičuda & Dirk Pijnenburg & Rinie Beuningen & Michal Holčapek & Libor Vítek & Magnus Ingelman-Sundberg & Oliver Burk & Thales Kronenberger & Radim Nencka & Petr Pavek
- 1-21 A feedback loop between Paxillin and Yorkie sustains Drosophila intestinal homeostasis and regeneration
by Dan Jiang & Pengyue Li & Yi Lu & Jiaxin Tao & Xue Hao & Xiaodong Wang & Wei Wu & Jinjin Xu & Haoen Zhang & Xiaoyu Li & Yixing Chen & Yunyun Jin & Lei Zhang
- 1-21 Single-cell and chromatin accessibility profiling reveals regulatory programs of pathogenic Th2 cells in allergic asthma
by Matarr Khan & Marlis Alteneder & Wolfgang Reiter & Thomas Krausgruber & Lina Dobnikar & Moritz Madern & Monika Waldherr & Christoph Bock & Markus Hartl & Wilfried Ellmeier & Johan Henriksson & Nicole Boucheron
- 1-22 Stress landscape of folding brain serves as a map for axonal pathfinding
by Akbar Solhtalab & Ali H. Foroughi & Lana Pierotich & Mir Jalil Razavi
- 1-22 Incomplete remyelination via therapeutically enhanced oligodendrogenesis is sufficient to recover visual cortical function
by Gustavo Della-Flora Nunes & Lindsay A. Osso & Johana A. Haynes & Lauren Conant & Michael A. Thornton & Michael E. Stockton & Katherine A. Brassell & Amanda Morris & Yessenia I. Mancha Corchado & John A. Gaynes & Anthony R. Chavez & Michaelanne B. Woerner & Deidre A. MacKenna & Aryan Alavi & Anne Danks & Alon Poleg-Polsky & Rohan Gandhi & Jeffrey A. Vivian & Daniel J. Denman & Ethan G. Hughes
- 1-22 Synthesis of ionizable lipopolymers using split-Ugi reaction for pulmonary delivery of various size RNAs and gene editing
by K. Yu. Vlasova & A. Kerr & N. D. Pennock & A. Jozic & D. K. Sahel & M. Gautam & N. T. V. Murthy & A. Roberts & M. W. Ali & K. D. MacDonald & J. M. Walker & R. Luxenhofer & G. Sahay
- 1-22 A protease-cleavable liposome for co-delivery of anti-PD-L1 and doxorubicin for colon cancer therapy in mice
by Yixuan Liu & Ying Xie & Yuling Chen & Jialun Duan & Chunjie Bao & Jinling Wang & Hexuan Feng & Mengjie Wang & Yuxin Ren & Peishan Li & Qian Luo & Jiarui Xu & Min Jiang & Yanchen Men & Yang Wu & Jianwei Li & Guiling Wang & Wanliang Lu
- 1-22 Dopamine prediction error signaling in a unique nigrostriatal circuit is critical for associative fear learning
by Daphne Zafiri & Ximena I. Salinas-Hernández & Eloah S. Biasi & Leonor Rebelo & Sevil Duvarci
- 1-22 Injectable ECM-mimetic dynamic hydrogels abolish ferroptosis-induced post-discectomy herniation through delivering nucleus pulposus progenitor cell-derived exosomes
by Wenkai Wang & Zhuo Cheng & Miao Yu & Ke Liu & Hongli Duan & Yang Zhang & Xinle Huang & Menghuan Li & Changqing Li & Yan Hu & Zhong Luo & Minghan Liu
- 1-22 p53-inducible lncRNA LOC644656 causes genotoxic stress-induced stem cell maldifferentiation and cancer chemoresistance
by Ai Tamura & Kazuyuki Yamagata & Takashi Kono & Masanori Fujimoto & Takahiro Fuchigami & Motoi Nishimura & Masataka Yokoyama & Akitoshi Nakayama & Naoko Hashimoto & Ikki Sakuma & Nobuyuki Mitsukawa & Yusuke Kawashima & Osamu Ohara & Shinichiro Motohashi & Eiryo Kawakami & Takashi Miki & Atsushi Onodera & Tomoaki Tanaka
- 1-22 Splicing accuracy varies across human introns, tissues, age and disease
by S. García-Ruiz & D. Zhang & E. K. Gustavsson & G. Rocamora-Perez & M. Grant-Peters & A. Fairbrother-Browne & R. H. Reynolds & J. W. Brenton & A. L. Gil-Martínez & Z. Chen & D. C. Rio & J. A. Botia & S. Guelfi & L. Collado-Torres & M. Ryten
- 1-22 Defining ortholog-specific UHRF1 inhibition by STELLA for cancer therapy
by Wenjing Bai & Jinxin Xu & Wenbin Gu & Danyang Wang & Ying Cui & Weidong Rong & Xiaoan Du & Xiaoxia Li & Cuicui Xia & Qingqing Gan & Guantao He & Huahui Guo & Jinfeng Deng & Yuqiong Wu & Ray-Whay Chiu Yen & Srinivasan Yegnasubramanian & Scott B. Rothbart & Cheng Luo & Linping Wu & Jinsong Liu & Stephen B. Baylin & Xiangqian Kong
- 1-22 SARS-CoV-2 ORF3a drives dynamic dense body formation for optimal viral infectivity
by Stella Hartmann & Lisa Radochonski & Chengjin Ye & Luis Martinez-Sobrido & Jueqi Chen
- 1-22 RNF20 links the DNA damage response and metabolic rewiring in lung cancer through HIF1α
by Hao Liu & Yongqin Tang & Anshu Singh & Joaquim Vong & Julio Cordero & Arthur Mathes & Rui Gao & Yanhan Jia & Boyan K. Garvalov & Till Acker & Gernot Poschet & Rüdiger Hell & Marc A. Schneider & Joerg Heineke & Thomas Wieland & Guillermo Barreto & Adelheid Cerwenka & Michael Potente & Sofia-Iris Bibli & Rajkumar Savai & Gergana Dobreva
- 1-22 Single-cell transcriptomics of bronchoalveolar lavage during PRRSV infection with different virulence
by Byeonghwi Lim & Seung-Chai Kim & Hwan-Ju Kim & Jae-Hwan Kim & Young-Jun Seo & Chiwoong Lim & Yejee Park & Sunirmal Sheet & Dahye Kim & Do-Hwan Lim & Kyeongsoon Park & Kyung-Tai Lee & Won-Il Kim & Jun-Mo Kim
- 1-22 Intratumor heterogeneity of HPV integration in HPV-associated head and neck cancer
by Noah Sasa & Toshihiro Kishikawa & Masashi Mori & Rie Ito & Yumie Mizoro & Masami Suzuki & Hirotaka Eguchi & Hidenori Tanaka & Takahito Fukusumi & Motoyuki Suzuki & Yukinori Takenaka & Keisuke Nimura & Yukinori Okada & Hidenori Inohara
- 1-22 Chondrocyte fatty acid oxidation drives osteoarthritis via SOX9 degradation and epigenetic regulation
by Zixuan Mei & Kamuran Yilamu & Weiyu Ni & Panyang Shen & Nan Pan & Huasen Chen & Yingfeng Su & Lei Guo & Qunan Sun & Zhaomei Li & Dongdong Huang & Xiangqian Fang & Shunwu Fan & Haitao Zhang & Shuying Shen
- 1-22 Chemotactic Zn micromotor for treatment of high blood ammonia-associated hepatic encephalopathy
by Ye Feng & Chao Gao & Xiuyun Peng & Bin Chen & Miaomiao Ding & Dailing Du & Jinghui Rong & Qi Lv & Daniela A. Wilson & Yingfeng Tu & Fei Peng
- 1-22 Osteocyte-derived extracellular vesicles mediate the bone-to-cartilage crosstalk and promote osteoarthritis progression
by Na Liu & Yuze Ma & Wang Gong & Xiaoyan Shao & Tianshu Shi & Lan Li & Wenshu Wu & Xiang Chen & Yong Shi & Pan Zhang & Jiaquan Lin & Chengzhi Wang & Depeng Fang & Lin Yang & Pu Wang & Wentian Gao & Yi He & Xueying An & Rui Du & Ying Chen & Bin Liu & Jianghui Qin & Dongyang Chen & Pingqiang Cai & Qing Jiang & Baosheng Guo
- 1-22 Reduced adult stem cell fate specification led to eye reduction in cave planarians
by Luiza O. Saad & Thomas F. Cooke & Kutay D. Atabay & Peter W. Reddien & Federico D. Brown
- 1-22 Single-cell RNA-sequencing reveals early mitochondrial dysfunction unique to motor neurons shared across FUS- and TARDBP-ALS
by Christoph Schweingruber & Jik Nijssen & Jonas Mechtersheimer & Stefan Reber & Mélanie Lebœuf & Niamh L. O’Brien & Irene Mei & Erin Hedges & Michaela Keuper & Julio Aguila Benitez & Vlad Radoi & Martin Jastroch & Marc-David Ruepp & Eva Hedlund
- 1-22 Single-cell RNA sequencing identifies CXADR as a fate determinant of the placental exchange surface
by Dafina M. Angelova & Aleksandra Tsolova & Malwina Prater & Noura Ballasy & Wendi Bacon & Russell S. Hamilton & Danielle Blackwell & Ziyi Yu & Xin Li & Xin Liu & Myriam Hemberger & D. Stephen Charnock-Jones
- 1-22 The spatially informed mFISHseq assay resolves biomarker discordance and predicts treatment response in breast cancer
by Evan D. Paul & Barbora Huraiová & Natália Valková & Natalia Matyasovska & Daniela Gábrišová & Soňa Gubová & Helena Ignačáková & Tomáš Ondris & Michal Gala & Liliane Barroso & Silvia Bendíková & Jarmila Bíla & Katarína Buranovská & Diana Drobná & Zuzana Krchňáková & Maryna Kryvokhyzha & Daniel Lovíšek & Viktoriia Mamoilyk & Veronika Mancikova & Nina Vojtaššáková & Michaela Ristová & Iñaki Comino-Méndez & Igor Andrašina & Pavel Morozov & Thomas Tuschl & Fresia Pareja & Jakob N. Kather & Pavol Čekan
- 1-22 FBXO31-mediated ubiquitination of OGT maintains O-GlcNAcylation homeostasis to restrain endometrial malignancy
by Na Zhang & Yang Meng & Song Mao & Huiling Ni & Canhua Huang & Licong Shen & Kun Fu & Lu Lv & Chunhong Yu & Piyanat Meekrathok & Chunmei Kuang & Fang Chen & Yu Zhang & Kai Yuan
- 1-22 RNA G-quadruplexes control mitochondria-localized mRNA translation and energy metabolism
by Leïla Dumas & Sauyeun Shin & Quentin Rigaud & Marie Cargnello & Beatriz Hernández-Suárez & Pauline Herviou & Nathalie Saint-Laurent & Marjorie Leduc & Morgane Gall & David Monchaud & Erik Dassi & Anne Cammas & Stefania Millevoi
- 1-22 Adipose progenitor cell-derived extracellular vesicles suppress macrophage M1 program to alleviate midlife obesity
by Qing Zhou & Jia Gao & Guorao Wu & Chenwei Wang & Yan Yang & Teng Huang & Yi Wang & Tiantian Yue & Zhichao Gao & Hao Xie & Fei Xiong & Ke Xiang & Tuying Yong & Wanguang Zhang & Tongtong Zhang & Wen Kong & Cai Chen & Shu Zhang & Qilin Yu & Xuemei Fan & Shiwei Liu & Yanjun Liu & Cong-Yi Wang
- 1-22 Deciphering neuronal variability across states reveals dynamic sensory encoding
by Shailaja Akella & Peter Ledochowitsch & Joshua H. Siegle & Hannah Belski & Daniel D. Denman & Michael A. Buice & Severine Durand & Christof Koch & Shawn R. Olsen & Xiaoxuan Jia
- 1-22 Enrichment of human IgA-coated bacterial vesicles in ulcerative colitis as a driver of inflammation
by Himadri B. Thapa & Christina A. Passegger & Dominik Fleischhacker & Paul Kohl & Yi-Chi Chen & Ratchara Kalawong & Carmen Tam-Amersdorfer & Michael R. Gerstorfer & Jana Strahlhofer & Kristina Schild-Prüfert & Ellen L. Zechner & Andreas Blesl & Lukas Binder & Georg A. Busslinger & Leo Eberl & Gregor Gorkiewicz & Herbert Strobl & Christoph Högenauer & Stefan Schild
- 1-22 SAMD9 senses cytosolic double-stranded nucleic acids in epithelial and mesenchymal cells to induce antiviral immunity
by Gaopeng Hou & Wandy Beatty & Lili Ren & Yaw Shin Ooi & Juhee Son & Yinxing Zhu & Qingyu Sheng & Wanyi Huang & Dian Li & Constin Liu & Olivia L. Welsh & Danica M. Sutherland & Terence S. Dermody & Chen Shen & Jia Liu & L. David Sibley & Siyuan Ding
- 1-22 Lymphatic-derived oxysterols promote anti-tumor immunity and response to immunotherapy in melanoma
by Mengzhu Sun & Laure Garnier & Romane Chevalier & Martin Roumain & Chen Wang & Julien Angelillo & Julien Montorfani & Robert Pick & Dale Brighouse & Nadine Fournier & David Tarussio & Stéphanie Tissot & Jean-Marc Lobaccaro & Tatiana V. Petrova & Camilla Jandus & Daniel E. Speiser & Manfred Kopf & Caroline Pot & Christoph Scheiermann & Krisztian Homicsko & Giulio G. Muccioli & Abhishek D. Garg & Stéphanie Hugues
- 1-22 Chromatin landscape at cis-regulatory elements orchestrates cell fate decisions in early embryogenesis
by Francesco Cardamone & Annamaria Piva & Eva Löser & Bastian Eichenberger & Mari Carmen Romero-Mulero & Fides Zenk & Emily J. Shields & Nina Cabezas-Wallscheid & Roberto Bonasio & Guido Tiana & Yinxiu Zhan & Nicola Iovino
- 1-22 Eukaryotic Elongation Factor 2 Kinase EFK-1/eEF2K promotes starvation resistance by preventing oxidative damage in C. elegans
by Junran Yan & Forum Bhanshali & Chiaki Shuzenji & Tsultrim T. Mendenhall & Shane K. B. Taylor & Glafira Ermakova & Xuanjin Cheng & Pamela Bai & Gahan Diwan & Donna Seraj & Joel N. Meyer & Poul H. Sorensen & Jessica H. Hartman & Stefan Taubert
- 1-22 USP2 inhibition unleashes CD47-restrained phagocytosis and enhances anti-tumor immunity
by Panpan Dai & Yishuang Sun & Zhengrong Huang & Yu-Tong Liu & Minling Gao & Hai-Ming Liu & Jie Shi & Chuan He & Bolin Xiang & Yingmeng Yao & Haisheng Yu & Gaoshan Xu & Lijun Kong & Xiangling Xiao & Xiyong Wang & Xue Zhang & Wenjun Xiong & Jing Hu & Dandan Lin & Bo Zhong & Gang Chen & Yan Gong & Conghua Xie & Jinfang Zhang
- 1-22 Integrative single-cell metabolomics and phenotypic profiling reveals metabolic heterogeneity of cellular oxidation and senescence
by Ziyi Wang & Siyuan Ge & Tiepeng Liao & Man Yuan & Wenwei Qian & Qi Chen & Wei Liang & Xiawei Cheng & Qinghua Zhou & Zhenyu Ju & Hongying Zhu & Wei Xiong
- 1-22 Engineered hypoxia-responsive albumin nanoparticles mediating mitophagy regulation for cancer therapy
by Wenyan Wang & Shun-Yu Yao & Jingjing Luo & Chendi Ding & Qili Huang & Yao Yang & Zhaoqing Shi & Jiachan Lin & Yu-Chen Pan & Xiaowei Zeng & Dong-Sheng Guo & Hongzhong Chen
- 1-22 DNA methylation modulates nucleosome retention in sperm and H3K4 methylation deposition in early mouse embryos
by Grigorios Fanourgakis & Laura Gaspa-Toneu & Pavel A. Komarov & Panagiotis Papasaikas & Evgeniy A. Ozonov & Sebastien A. Smallwood & Antoine H. F. M. Peters
- 1-22 Divergent actions of physiological and pathological amyloid-β on synapses in live human brain slice cultures
by Robert I. McGeachan & Soraya Meftah & Lewis W. Taylor & James H. Catterson & Danilo Negro & Calum Bonthron & Kristján Holt & Jane Tulloch & Jamie L. Rose & Francesco Gobbo & Ya Yin Chang & Jamie Elliott & Lauren McLay & Declan King & Imran Liaquat & Tara L. Spires-Jones & Sam A. Booker & Paul M. Brennan & Claire S. Durrant
- 1-22 Non-AUG HIV-1 uORF translation elicits specific T cell immune response and regulates viral transcript expression
by Emmanuel Labaronne & Didier Décimo & Lisa Bertrand & Laura Guiguettaz & Thibault J. M. Sohier & David Cluet & Valérie Vivet-Boudou & Ana Luiza Chaves Valadão & Clara Dahoui & Pauline François & Isabelle Hatin & Olivier Lambotte & Assia Samri & Brigitte Autran & Lucie Etienne & Caroline Goujon & Jean-Christophe Paillart & Olivier Namy & Bertha Cecilia Ramirez & Théophile Ohlmann & Arnaud Moris & Emiliano P. Ricci
- 1-22 Biosilicification-mimicking chiral nanostructures for targeted treatment of inflammatory bowel disease
by Miao Xu & Wei Xin & Jiabin Xu & Anya Wang & Shuai Ma & Di Dai & Yidan Wang & Dongmei Yang & Lin Zhao & Heran Li
- 1-22 BRD4 modulator ZL0580 and LEDGINs additively block and lock HIV-1 transcription
by Eline Pellaers & Julie Janssens & Lore Wils & Alexe Denis & Anayat Bhat & Siska Belle & Da Feng & Frauke Christ & Peng Zhan & Zeger Debyser
- 1-22 ANP32E drives vulnerability to ATR inhibitors by inducing R-loops-dependent transcription replication conflicts in triple negative breast cancer
by Sara Lago & Vittoria Poli & Lisa Fol & Mattia Botteon & Federica Busi & Alice Turdo & Miriam Gaggianesi & Yari Ciani & Giacomo D’Amato & Luca Fagnocchi & Alessandra Fasciani & Francesca Demichelis & Matilde Todaro & Alessio Zippo
- 1-22 Expression of ENL YEATS domain tumor mutations in nephrogenic or stromal lineage impairs kidney development
by Zhaoyu Xue & Hongwen Xuan & Kin Lau & Yangzhou Su & Marc Wegener & Kuai Li & Lisa Turner & Marie Adams & Xiaobing Shi & Hong Wen
- 1-22 An oncohistone-driven H3.3K27M/CREB5/ID1 axis maintains the stemness and malignancy of diffuse intrinsic pontine glioma
by Wei Zhou & Cheng Xu & Shuangrui Yang & Haocheng Li & Changcun Pan & Zhuang Jiang & Luyang Xie & Xiaohan Li & Huimin Qiao & Da Mi & Yujie Tang & Liwei Zhang & Qiaoran Xi
- 1-22 Nr4a1 and Nr4a3 redundantly control clonal deletion and contribute to an anergy-like transcriptome in auto-reactive thymocytes to impose tolerance in mice
by Hailyn V. Nielsen & Letitia Yang & James L. Mueller & Alexander J. Ritter & Ryosuke Hiwa & Irina Proekt & Elze Rackaityte & Dominik Aylard & Mansi Gupta & Christopher D. Scharer & Mark S. Anderson & Byron B. Au-Yeung & Julie Zikherman
- 1-22 The protein circPETH-147aa regulates metabolic reprogramming in hepatocellular carcinoma cells to remodel immunosuppressive microenvironment
by Tian Lan & Fengwei Gao & Yunshi Cai & Yinghao Lv & Jiang Zhu & Hu Liu & Sinan Xie & Haifeng Wan & Haorong He & Kunlin Xie & Chang Liu & Hong Wu
- 1-22 Comprehensive promotion of iPSC-CM maturation by integrating metabolic medium with nanopatterning and electrostimulation
by Wener Li & Xiaojing Luo & Anna Strano & Shakthi Arun & Oliver Gamm & Mareike S. Poetsch & Marcel Hasse & Robert-Patrick Steiner & Konstanze Fischer & Jessie Pöche & Ying Ulbricht & Mathias Lesche & Giulia Trimaglio & Ali El-Armouche & Andreas Dahl & Peter Mirtschink & Kaomei Guan & Mario Schubert
- 1-22 CD133+PD-L1+ cancer cells confer resistance to adoptively transferred engineered macrophage-based therapy in melanoma
by Jiaojiao Xu & Zhe Li & Qinli Tong & Sihang Zhang & Jianchen Fang & Aihua Wu & Guoguang Wei & Chen Zhang & Sheng Yu & Binbin Zheng & Hongzheng Lin & Xueling Liao & Zeyu Xiao & Wei Lu
- 1-22 Tensor-FLAMINGO unravels the complexity of single-cell spatial architectures of genomes at high-resolution
by Hao Wang & Jiaxin Yang & Xinrui Yu & Yu Zhang & Jianliang Qian & Jianrong Wang
- 1-22 Vesicular and non-vesicular extracellular small RNAs direct gene silencing in a plant-interacting bacterium
by Antinéa Ravet & Jérôme Zervudacki & Meenu Singla-Rastogi & Magali Charvin & Odon Thiebeauld & Alvaro L. Perez-Quintero & Lucas Courgeon & Adrien Candat & Liam Lebeau & Antonio Emidio Fortunato & Venugopal Mendu & Lionel Navarro
- 1-22 Extended coverage of human serum glycosphingolipidome by 4D-RP-LC TIMS-PASEF unravels association with Parkinson’s disease
by Huong Giang Vo & Gabriel Gonzalez-Escamilla & Daniela Mirzac & Lilia Rotaru & Damian Herz & Sergiu Groppa & Laura Bindila
- 1-22 Pluripotency factor Tex10 finetunes Wnt signaling for spermatogenesis and primordial germ cell development
by Feifei Yuan & Jihong Yang & Fanglin Ma & Zhe Hu & Vikas Malik & Ruge Zang & Dan Li & Xianle Shi & Xin Huang & Hongwei Zhou & Jianlong Wang
- 1-23 Mitochondria are positioned at dendritic branch induction sites, a process requiring rhotekin2 and syndapin I
by Jessica Tröger & Regina Dahlhaus & Anne Bayrhammer & Dennis Koch & Michael M. Kessels & Britta Qualmann
- 1-23 Dysregulation of N-terminal acetylation causes cardiac arrhythmia and cardiomyopathy
by Daisuke Yoshinaga & Isabel Craven & Rui Feng & Maksymilian Prondzynski & Kevin Shani & Yashasvi Tharani & Joshua Mayourian & Milosh Joseph & David Walker & Raul H. Bortolin & Chrystalle Katte Carreon & Bridget Boss & Sheila Upton & Kevin Kit Parker & William T. Pu & Vassilios J. Bezzerides
- 1-23 Cellular interactions within the immune microenvironment underpins resistance to cell cycle inhibition in breast cancers
by Jason I. Griffiths & Patrick A. Cosgrove & Eric F. Medina & Aritro Nath & Jinfeng Chen & Frederick R. Adler & Jeffrey T. Chang & Qamar J. Khan & Andrea H. Bild
- 1-23 The motor neuron m6A repertoire governs neuronal homeostasis and FTO inhibition mitigates ALS symptom manifestation
by Ya-Ping Yen & Ting-Hsiang Lung & Ee Shan Liau & Chuan-Che Wu & Guan-Lin Huang & Fang-Yu Hsu & Mien Chang & Zheng-Dao Yang & Chia-Yi Huang & Zhong Zheng & Wei Zhao & Jui-Hung Hung & Chuan He & Qing Nie & Jun-An Chen
- 1-23 Single cell immunoprofile of synovial fluid in rheumatoid arthritis with TNF/JAK inhibitor treatment
by Xuyang Xia & Chenjia He & Zhinan Xue & Yuelan Wang & Yun Qin & Zhixiang Ren & Yupeng Huang & Han Luo & Hai-Ning Chen & Wei-Han Zhang & Li-Bin Huang & Yunying Shi & Yangjuan Bai & Bei Cai & Lanlan Wang & Feng Zhang & Maoxiang Qian & Wei Zhang & Yang Shu & Geng Yin & Heng Xu & Qibing Xie
- 1-23 Investigative needle core biopsies support multimodal deep-data generation in glioblastoma
by Kenny K. H. Yu & Sreyashi Basu & Gerard Baquer & Ryuhjin Ahn & Jennifer Gantchev & Sonali Jindal & Michael S. Regan & Zaki Abou-Mrad & Michael C. Prabhu & Marc J. Williams & Alicia D. D’Souza & Seth W. Malinowski & Kelsey Hopland & Yuval Elhanati & Sylwia A. Stopka & Alexei Stortchevoi & Charles Couturier & Zhong He & Jingjing Sun & Yulong Chen & Alexsandra B. Espejo & Kin Hoe Chow & Smitha Yerrum & Pei-Lun Kao & Brittany Parker Kerrigan & Lisa Norberg & Douglas Nielsen & Vinay K. Puduvalli & Jason Huse & Rameen Beroukhim & Betty Y. S. Kim & Sangeeta Goswami & Adrienne Boire & Sarah Frisken & Michael J. Cima & Matthias Holdhoff & Calixto-Hope G. Lucas & Chetan Bettegowda & Stuart S. Levine & Tejus A. Bale & Cameron Brennan & David A. Reardon & Frederick F. Lang & E. Antonio Chiocca & Keith L. Ligon & Forest M. White & Padmanee Sharma & Viviane Tabar & Nathalie Y. R. Agar
- 1-23 Broadband visual stimuli improve neuronal representation and sensory perception
by Elisabeta Balla & Gerion Nabbefeld & Christopher Wiesbrock & Jenice Linde & Severin Graff & Simon Musall & Björn M. Kampa
- 1-23 The DNA methylation landscape of primary triple-negative breast cancer
by Mattias Aine & Deborah F. Nacer & Elsa Arbajian & Srinivas Veerla & Anna Karlsson & Jari Häkkinen & Henrik J. Johansson & Frida Rosengren & Johan Vallon-Christersson & Åke Borg & Johan Staaf
- 1-23 Mitochondrial complexity is regulated at ER-mitochondria contact sites via PDZD8-FKBP8 tethering
by Koki Nakamura & Saeko Aoyama-Ishiwatari & Takahiro Nagao & Mohammadreza Paaran & Christopher J. Obara & Yui Sakurai-Saito & Jake Johnston & Yudan Du & Shogo Suga & Masafumi Tsuboi & Makoto Nakakido & Kouhei Tsumoto & Yusuke Kishi & Yukiko Gotoh & Chulhwan Kwak & Hyun-Woo Rhee & Jeong Kon Seo & Hidetaka Kosako & Clint Potter & Bridget Carragher & Jennifer Lippincott-Schwartz & Franck Polleux & Yusuke Hirabayashi
- 1-23 Auricular malformations are driven by copy number variations in a hierarchical enhancer cluster and a dominant enhancer recapitulates human pathogenesis
by Xiaopeng Xu & Qi Chen & Qingpei Huang & Timothy C. Cox & Hao Zhu & Jintian Hu & Xi Han & Ziqiu Meng & Bingqing Wang & Zhiying Liao & Wenxin Xu & Baichuan Xiao & Ruirui Lang & Jiqiang Liu & Jian Huang & Xiaokai Tang & Jinmo Wang & Qiang Li & Ting Liu & Qingguo Zhang & Stylianos E. Antonarakis & Jiao Zhang & Xiaoying Fan & Huisheng Liu & Yong-Biao Zhang
- 1-23 Deletion of splicing factor Cdc5 in Toxoplasma disrupts transcriptome integrity, induces abortive bradyzoite formation, and prevents acute infection in mice
by Poonam Kashyap & Kalyani R. Aswale & Abhijit S. Deshmukh
- 1-23 Snord67 promotes breast cancer metastasis by guiding U6 modification and modulating the splicing landscape
by Yvonne L. Chao & Katherine I. Zhou & Kwame K. Forbes & Alessandro Porrello & Gabrielle M. Gentile & Yinzhou Zhu & Aaron C. Chack & Dixcy J. S. John Mary & Haizhou Liu & Eric Cockman & Lincy Edatt & Grant A. Goda & Justin J. Zhao & Hala Abou Assi & Hannah J. Wiedner & Yihsuan Tsai & Lily Wilkinson & Amanda E. D. Swearingen & Lisa A. Carey & Jimena Giudice & Daniel Dominguez & Christopher L. Holley & Chad V. Pecot
- 1-23 Learning and actioning general principles of cancer cell drug sensitivity
by Francesco Carli & Pierluigi Chiaro & Mariangela Morelli & Chakit Arora & Luisa Bisceglia & Natalia Oliveira Rosa & Alice Cortesi & Sara Franceschi & Francesca Lessi & Anna Luisa Stefano & Orazio Santo Santonocito & Francesco Pasqualetti & Paolo Aretini & Pasquale Miglionico & Giuseppe R. Diaferia & Fosca Giannotti & Pietro Liò & Miquel Duran-Frigola & Chiara Maria Mazzanti & Gioacchino Natoli & Francesco Raimondi
- 1-23 MARTRE family proteins negatively regulate CCR4-NOT activity to protect poly(A) tail length and promote translation of maternal mRNA
by Jing Yang & Jiachen Bu & Bowen Liu & Yusheng Liu & Zhuqiang Zhang & Ziyi Li & Falong Lu & Bing Zhu & Yingfeng Li
- 1-23 Proximity proteomics reveals a mechanism of fatty acid transfer at lipid droplet-mitochondria- endoplasmic reticulum contact sites
by Ayenachew Bezawork-Geleta & Camille J. Devereux & Stacey N. Keenan & Jieqiong Lou & Ellie Cho & Shuai Nie & David P. Souza & Vinod K. Narayana & Nicole A. Siddall & Carlos H. M. Rodrigues & Stephanie Portelli & Tenghao Zheng & Hieu T. Nim & Mirana Ramialison & Gary R. Hime & Garron T. Dodd & Elizabeth Hinde & David B. Ascher & David A. Stroud & Matthew J. Watt
- 1-23 Targeting senescent hepatocytes for treatment of metabolic dysfunction-associated steatotic liver disease and multi-organ dysfunction
by Kuo Du & David S. Umbaugh & Liuyang Wang & Ji Hye Jun & Rajesh K. Dutta & Seh Hoon Oh & Niansheng Ren & Qiaojuan Zhang & Dennis C. Ko & Ana Ferreira & Jon Hill & Guannan Gao & Steven S. Pullen & Vaibhav Jain & Simon Gregory & Manal F. Abdelmalek & Anna Mae Diehl
- 1-23 Cortical circuits for cross-modal generalization
by Maëlle Guyoton & Giulio Matteucci & Charlie G. Foucher & Matthew P. Getz & Julijana Gjorgjieva & Sami El-Boustani
- 1-23 Targeting ELOVL6 to disrupt c-MYC driven lipid metabolism in pancreatic cancer enhances chemosensitivity
by Ana García García & María Ferrer Aporta & Germán Vallejo Palma & Antonio Giráldez Trujillo & Raquel Castillo-González & David Calzón Lozano & Alberto Mora Perdiguero & Raúl Muñoz Velasco & Miguel Colina Castro & Elena Simone Benito & Raúl Torres-Ruiz & Sandra Rodriguez-Perales & Jonas Dehairs & Johannes V. Swinnen & Juan Carlos Garcia-Cañaveras & Agustín Lahoz & Sandra Montalvo Quirós & Carlos Pozo-Rojas & Clara Luque Rioja & Francisco Monroy & Diego Herráez-Aguilar & Marina Alonso Riaño & José Luis Rodríguez Peralto & Víctor Javier Sánchez-Arévalo Lobo
- 1-23 Distribution of the four type VI secretion systems in Pseudomonas aeruginosa and classification of their core and accessory effectors
by Antonia Habich & Verónica Chaves Vargas & Luca A. Robinson & Luke P. Allsopp & Daniel Unterweger
- 1-23 A guidance to intelligent metamaterials and metamaterials intelligence
by Chao Qian & Ido Kaminer & Hongsheng Chen
- 1-23 CDK4 inactivation inhibits apoptosis via mitochondria-ER contact remodeling in triple-negative breast cancer
by Dorian V. Ziegler & Kanishka Parashar & Lucia Leal-Esteban & Jaime López-Alcalá & Wilson Castro & Nadège Zanou & Laia Martinez-Carreres & Katharina Huber & Xavier Pascal Berney & María M. Malagón & Catherine Roger & Marie-Agnès Berger & Yves Gouriou & Giulia Paone & Hector Gallart-Ayala & George Sflomos & Carlos Ronchi & Julijana Ivanisevic & Cathrin Brisken & Jennifer Rieusset & Melita Irving & Lluis Fajas
- 1-23 Syngap1 promotes cognitive function through regulation of cortical sensorimotor dynamics
by Thomas Vaissiere & Sheldon D. Michaelson & Thomas Creson & Jessie Goins & Daniel Fürth & Diana Balazsfi & Camilo Rojas & Randall Golovin & Konstantinos Meletis & Courtney A. Miller & Daniel O’Connor & Lorenzo Fontolan & Gavin Rumbaugh
- 1-23 Hippocampal-entorhinal cognitive maps and cortical motor system represent action plans and their outcomes
by Irina Barnaveli & Simone Viganò & Daniel Reznik & Patrick Haggard & Christian F. Doeller
- 1-23 Orphan G protein-coupled receptor GPRC5B controls macrophage function by facilitating prostaglandin E receptor 2 signaling
by Jeonghyeon Kwon & Haruya Kawase & Kenny Mattonet & Stefan Guenther & Lisa Hahnefeld & Jamal Shamsara & Jan Heering & Michael Kurz & Sina Kirchhofer & Cornelius Krasel & Michaela Ulrich & Margherita Persechino & Sripriya Murthy & Cesare Orlandi & Christian D. Sadik & Gerd Geisslinger & Moritz Bünemann & Peter Kolb & Stefan Offermanns & Nina Wettschureck
- 1-23 INSTINCT: Multi-sample integration of spatial chromatin accessibility sequencing data via stochastic domain translation
by Yuyao Liu & Zhen Li & Xiaoyang Chen & Xuejian Cui & Zijing Gao & Rui Jiang
- 1-23 Multiomic analysis of human kidney disease identifies a tractable inflammatory and pro-fibrotic tubular cell phenotype
by Maximilian Reck & David P. Baird & Stefan Veizades & Callum Sutherland & Rachel M. B. Bell & Heeyoun Hur & Carolynn Cairns & Piotr P. Janas & Ross Campbell & Andy Nam & Wei Yang & Nathan Schurman & Claire Williams & Eoin O’Sullivan & Meryam Beniazza & Andrea Corsinotti & Christopher Bellamy & Jeremy Hughes & Alexander Laird & Laura Denby & Tamir Chandra & David A. Ferenbach & Bryan R. Conway
- 1-23 Oral ENPP1 inhibitor designed using generative AI as next generation STING modulator for solid tumors
by Congying Pu & Hui Cui & Huaxing Yu & Xin Cheng & Man Zhang & Luoheng Qin & Zhilin Ning & Wen Zhang & Shan Chen & Yuhang Qian & Feng Wang & Ling Wang & Xiaoxia Lin & David Gennert & Frank W. Pun & Feng Ren & Alex Zhavoronkov
- 1-23 Tissue shear as a cue for aligning planar polarity in the developing Drosophila wing
by Su Ee Tan & David Strutt
- 1-23 Dopaminergic signaling to ventral striatum neurons initiates sniffing behavior
by Natalie L. Johnson & Anamaria Cotelo-Larrea & Lucas A. Stetzik & Umit M. Akkaya & Zihao Zhang & Marie A. Gadziola & Adrienn G. Varga & Minghong Ma & Daniel W. Wesson
- 1-23 High-content screening identifies ganoderic acid A as a senotherapeutic to prevent cellular senescence and extend healthspan in preclinical models
by Li Chen & Bangfu Wu & Li Mo & Huimin Chen & Xingzhu Yin & Ying Zhao & ZhaoYu Cui & Feipeng Cui & Liangkai Chen & Qianchun Deng & Chao Gao & Ping Yao & Yanyan Li & Yuhan Tang
- 1-23 Engineering nanozyme immunomodulator with magnetic targeting effect for cascade-enzyodynamic and ultrasound-reinforced metallo-immunotherapy in prostate carcinoma
by Yandong Wang & Haodong Li & Junyang Lin & Yutang Li & Keqin Zhang & Hui Li & Qiang Fu & Yanyan Jiang
- 1-23 S-nitrosylation of EZH2 alters PRC2 assembly, methyltransferase activity, and EZH2 stability to maintain endothelial homeostasis
by Ashima Sakhuja & Ritobrata Bhattacharyya & Yash Tushar Katakia & Shyam Kumar Ramakrishnan & Srinjoy Chakraborty & Hariharan Jayakumar & Shailesh Mani Tripathi & Niyati Pandya Thakkar & Sumukh Thakar & Sandeep Sundriyal & Shibasish Chowdhury & Syamantak Majumder
- 1-23 PNPLA6 regulates retinal homeostasis by choline through phospholipid turnover
by Takashi Ono & Yoshitaka Taketomi & Takayoshi Higashi & Hiroyasu Sato & Chika Mochizuki-Ono & Yuki Nagasaki & Takashi Ueta & Takashi Miyai & Suzumi M. Tokuoka & Yoshiya Oda & Yasumasa Nishito & Tomio Ono & Choji Taya & Satoru Arata & Sumiko Watanabe & Tomoyoshi Soga & Tetsuya Hirabayashi & Makoto Aihara & Makoto Murakami
- 1-23 GABAergic neurons in central amygdala contribute to orchestrating anxiety-like behaviors and breathing patterns
by Xiaoyi Wang & Shangyu Bi & Ziteng Yue & Xinxin Chen & Yuhang Liu & Tianjiao Deng & Liuqi Shao & Xinyi Jing & Cuidie Wang & Yakun Wang & Wei He & Hongxiao Yu & Luo Shi & Fang Yuan & Sheng Wang
- 1-23 Structural mechanisms for centrosomal recruitment and organization of the microtubule nucleator γ-TuRC
by Qi Gao & Florian W. Hofer & Sebastian Filbeck & Bram J. A. Vermeulen & Martin Würtz & Annett Neuner & Charlotte Kaplan & Maja Zezlina & Cornelia Sala & Hyesu Shin & Oliver J. Gruss & Elmar Schiebel & Stefan Pfeffer
- 1-23 Recapitulation of endochondral ossification by hPSC-derived SOX9+ sclerotomal progenitors
by Jingfei Xiong & Runxin Ma & Kun Xie & Ce Shan & Hanyi Chen & Yuqing Wang & Yuansong Liao & Yanhui Deng & Guogen Ye & Yifu Wang & Qing Zhu & Yunqiu Zhang & Haoyang Cai & Weihua Guo & Yike Yin & Zhonghan Li
- 1-23 Optineurin-facilitated axonal mitochondria delivery promotes neuroprotection and axon regeneration
by Dong Liu & Hannah C. Webber & Fuyun Bian & Yangfan Xu & Manjari Prakash & Xue Feng & Ming Yang & Hang Yang & In-Jee You & Liang Li & Liping Liu & Pingting Liu & Haoliang Huang & Chien-Yi Chang & Liang Liu & Sahil H. Shah & Anna Torre & Derek S. Welsbie & Yang Sun & Xin Duan & Jeffrey Louis Goldberg & Marcus Braun & Zdenek Lansky & Yang Hu
- 1-23 Self-disassembling nanoparticles as oral nanotherapeutics targeting intestinal microenvironment
by Jinwon Park & Yina Wu & Quoc-Viet Le & Jung Suk Kim & Enzhen Xu & Jaiwoo Lee & Yu-Kyoung Oh
- 1-23 Matrix mechano-sensing at the invasive front induces a cytoskeletal and transcriptional memory supporting metastasis
by Oscar Maiques & Marta C. Sallan & Roman Laddach & Pahini Pandya & Adrian Varela & Eva Crosas-Molist & Jaume Barcelo & Olivia Courbot & Yanbo Liu & Vittoria Graziani & Youssef Arafat & Joanne Sewell & Irene Rodriguez-Hernandez & Bruce Fanshawe & Yaiza Jung-Garcia & Paul RC Imbert & Eloise M. Grasset & Jean Albrengues & Maria Santacana & Anna Macià & Jordi Tarragona & Xavier Matias-Guiu & Rosa M. Marti & Sophia Tsoka & Cedric Gaggioli & Jose L. Orgaz & Gilbert O. Fruhwirth & Fredrik Wallberg & Kai Betteridge & Constantino Carlos Reyes-Aldasoro & Syed Haider & Andrejs Braun & Sophia N. Karagiannis & Alberto Elosegui-Artola & Victoria Sanz-Moreno
- 1-23 Spatiotemporally resolved mapping of extracellular proteomes via in vivo-compatible TyroID
by Zijuan Zhang & Yankun Wang & Wenjie Lu & Xiaofei Wang & Hongyang Guo & Xuanzhen Pan & Zeyu Liu & Zhaofa Wu & Wei Qin
- 1-23 Suppressing recurrence in Sonic Hedgehog subgroup medulloblastoma using the OLIG2 inhibitor CT-179
by Yuchen Li & Chaemin Lim & Taylor Dismuke & Daniel S. Malawsky & Sho Oasa & Zara C. Bruce & Carolin Offenhäuser & Ulrich Baumgartner & Rochelle C. J. D’Souza & Stacey L. Edwards & Juliet D. French & Lucy S. H. Ock & Sneha Nair & Haran Sivakumaran & Lachlan Harris & Andrey P. Tikunov & Duhyeong Hwang & Coral Del Mar Alicea Pauneto & Mellissa Maybury & Timothy Hassall & Brandon Wainwright & Santosh Kesari & Gregory Stein & Michael Piper & Terrance G. Johns & Marina Sokolsky-Papkov & Lars Terenius & Vladana Vukojević & Leon F. McSwain & Timothy R. Gershon & Bryan W. Day
- 1-23 Histone methyltransferase ASH1L primes metastases and metabolic reprogramming of macrophages in the bone niche
by Chenling Meng & Kevin Lin & Wei Shi & Hongqi Teng & Xinhai Wan & Anna DeBruine & Yin Wang & Xin Liang & Javier Leo & Feiyu Chen & Qianlin Gu & Jie Zhang & Vivien Van & Kiersten L. Maldonado & Boyi Gan & Li Ma & Yue Lu & Di Zhao
- 1-23 scPRINT: pre-training on 50 million cells allows robust gene network predictions
by Jérémie Kalfon & Jules Samaran & Gabriel Peyré & Laura Cantini
- 1-23 Regulatory T cells in the mouse hypothalamus control immune activation and ameliorate metabolic impairments in high-calorie environments
by Maike Becker & Stefanie Kälin & Anne H. Neubig & Michael Lauber & Daria Opaleva & Hannah Hipp & Victoria K. Salb & Verena B. Ott & Beata Legutko & Roland E. Kälin & Markus Hippich & Martin G. Scherm & Lucas F. R. Nascimento & Isabelle Serr & Fabian Hosp & Alexei Nikolaev & Alma Mohebiany & Martin Krueger & Bianca Flachmeyer & Michael W. Pfaffl & Bettina Haase & Chun-Xia Yi & Sarah Dietzen & Tobias Bopp & Stephen C. Woods & Ari Waisman & Benno Weigmann & Matthias Mann & Matthias H. Tschöp & Carolin Daniel
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