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Science-Based Business: Knowledge Capital or Entrepreneurial Ability? Theory and Evidence from a Survey of Biotechnology Start-ups

Author

Listed:
  • Yuji Honjo

    (Chuo University)

  • Sadao Nagaoka

    (Hitotsubashi University)

  • Kenta Nakamura

    (Kobe University)

  • Serguey Braguinsky

    (Carnegie Mellon University)

Abstract

We present a model of science-based entrepreneurship where ideas initially produced by researchers with scientific knowledge capital may be developed by high-ability entrepreneurs. With moderate verification costs, startups continuously managed by inventors-founders coexist in equilibrium with startups that experience entrepreneurial turnover. The model predicts that startups managed by non-founder entrepreneurs would on average outperform the startups managed by their founders, and that better functioning of the market for entrepreneurial talent should result in more entrepreneurial turnover in equilibrium which in its turn leads to more ideas being commercialized and higher rewards to successful startups. We probe the implications of the model using a unique dataset from the survey of a representative sample of biotechnology startups in Japan and we find them to be broadly supported in the data.

Suggested Citation

  • Yuji Honjo & Sadao Nagaoka & Kenta Nakamura & Serguey Braguinsky, 2011. "Science-Based Business: Knowledge Capital or Entrepreneurial Ability? Theory and Evidence from a Survey of Biotechnology Start-ups," 2011 Meeting Papers 1270, Society for Economic Dynamics.
    • Handle: RePEc:red:sed011:1270
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    References listed on IDEAS

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    Cited by:

    1. Shiaw Jia Eyo, 2014. "Japan's Bioventures: Past, Present and Future," International Journal of Innovation and Technology Management (IJITM), World Scientific Publishing Co. Pte. Ltd., vol. 11(05), pages 1-22.
    2. Bernardo Balboni & Guido Bortoluzzi, 2015. "Business Model Adaptation and the Success of New Ventures," Journal of Entrepreneurship, Management and Innovation, Fundacja Upowszechniająca Wiedzę i Naukę "Cognitione", vol. 11(1), pages 119-140.

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    More about this item

    JEL classification:

    • O31 - Economic Development, Innovation, Technological Change, and Growth - - Innovation; Research and Development; Technological Change; Intellectual Property Rights - - - Innovation and Invention: Processes and Incentives
    • O32 - Economic Development, Innovation, Technological Change, and Growth - - Innovation; Research and Development; Technological Change; Intellectual Property Rights - - - Management of Technological Innovation and R&D

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