IDEAS home Printed from https://ideas.repec.org/a/spr/scient/v117y2018i1d10.1007_s11192-018-2846-z.html
   My bibliography  Save this article

Joint modeling of the association between NIH funding and its three primary outcomes: patents, publications, and citation impact

Author

Listed:
  • Fengqing Zhang

    (Drexel University)

  • Erjia Yan

    (Drexel University)

  • Xin Niu

    (Drexel University)

  • Yongjun Zhu

    (Sungkyunkwan University)

Abstract

This paper examines the impact of NIH funding on research outcomes using data from 108,803 projects funded by NIH between January 2009 and March 2017. We extend the prior knowledge on this topic by incorporating the correlation structure of multiple research outcomes, as well as a comprehensive list of grant-level features capturing information on funding size, gender composition and funding type. Specifically, we utilize partial least squares regression (PLS) to jointly model all three primary outcomes (publications, patents and citation impact) and identify the effects of grant-level features on research outputs. Our results show that joint modeling of research outcomes via PLS yields a more accurate prediction than analyzing each outcome separately. Additionally, we find that when other grant-level features are held constant, a 2-year-longer project duration would produce a similar improvement in research outputs to that achieved by $1 million in additional funding. Based on this finding, we recommend no-cost extension of funded projects instead of increased funding support to achieve a comparable increase in research outputs. Promoting multi-organizational grants is found to be more effective for increasing patents, whereas encouraging multiple-PI grants is more productive in terms of publications and citation impact. Of the various NIH grant types, program project/center grants (P series) and research training grants (T series) are the two most productive and impactful. Results also suggest that projects with a higher proportion of male PIs tend to produce more research outputs. This finding, however, needs to be interpreted with caution due to the limitation of our data set.

Suggested Citation

  • Fengqing Zhang & Erjia Yan & Xin Niu & Yongjun Zhu, 2018. "Joint modeling of the association between NIH funding and its three primary outcomes: patents, publications, and citation impact," Scientometrics, Springer;Akadémiai Kiadó, vol. 117(1), pages 591-602, October.
  • Handle: RePEc:spr:scient:v:117:y:2018:i:1:d:10.1007_s11192-018-2846-z
    DOI: 10.1007/s11192-018-2846-z
    as

    Download full text from publisher

    File URL: http://link.springer.com/10.1007/s11192-018-2846-z
    File Function: Abstract
    Download Restriction: Access to the full text of the articles in this series is restricted.

    File URL: https://libkey.io/10.1007/s11192-018-2846-z?utm_source=ideas
    LibKey link: if access is restricted and if your library uses this service, LibKey will redirect you to where you can use your library subscription to access this item
    ---><---

    As the access to this document is restricted, you may want to search for a different version of it.

    References listed on IDEAS

    as
    1. Benjamin F. Jones, 2009. "The Burden of Knowledge and the "Death of the Renaissance Man": Is Innovation Getting Harder?," The Review of Economic Studies, Review of Economic Studies Ltd, vol. 76(1), pages 283-317.
    2. David C. Mowery & Bhaven N. Sampat & Arvids A. Ziedonis, 2002. "Learning to Patent: Institutional Experience, Learning, and the Characteristics of U.S. University Patents After the Bayh-Dole Act, 1981-1992," Management Science, INFORMS, vol. 48(1), pages 73-89, January.
    3. Pierre Azoulay & Joshua S Graff Zivin & Danielle Li & Bhaven N Sampat, 2019. "Public R&D Investments and Private-sector Patenting: Evidence from NIH Funding Rules," The Review of Economic Studies, Review of Economic Studies Ltd, vol. 86(1), pages 117-152.
    4. Rebecca Henderson & Adam B. Jaffe & Manuel Trajtenberg, 1998. "Universities As A Source Of Commercial Technology: A Detailed Analysis Of University Patenting, 1965-1988," The Review of Economics and Statistics, MIT Press, vol. 80(1), pages 119-127, February.
    5. Jue Wang & Philip Shapira, 2011. "Funding acknowledgement analysis: an enhanced tool to investigate research sponsorship impacts: the case of nanotechnology," Scientometrics, Springer;Akadémiai Kiadó, vol. 87(3), pages 563-586, June.
    6. Jacob, Brian A. & Lefgren, Lars, 2011. "The impact of research grant funding on scientific productivity," Journal of Public Economics, Elsevier, vol. 95(9), pages 1168-1177.
    7. Wesley M. Cohen & Richard R. Nelson & John P. Walsh, 2003. "Links and Impacts: The Influence of Public Research on Industrial R&D," Chapters, in: Aldo Geuna & Ammon J. Salter & W. Edward Steinmueller (ed.), Science and Innovation, chapter 4, Edward Elgar Publishing.
    8. MacGarvie, Megan, 2005. "The determinants of international knowledge diffusion as measured by patent citations," Economics Letters, Elsevier, vol. 87(1), pages 121-126, April.
    9. Walsh, John P. & Cohen, Wesley M. & Cho, Charlene, 2007. "Where excludability matters: Material versus intellectual property in academic biomedical research," Research Policy, Elsevier, vol. 36(8), pages 1184-1203, October.
    10. Adam Jaffe & Manuel Trajtenberg, 1999. "International Knowledge Flows: Evidence From Patent Citations," Economics of Innovation and New Technology, Taylor & Francis Journals, vol. 8(1-2), pages 105-136.
    11. Pierre Azoulay & Waverly Ding & Toby Stuart, 2009. "The Impact Of Academic Patenting On The Rate, Quality And Direction Of (Public) Research Output," Journal of Industrial Economics, Wiley Blackwell, vol. 57(4), pages 637-676, December.
    12. Anonymous, 1962. "Economic and Social Council," International Organization, Cambridge University Press, vol. 16(3), pages 587-596, July.
    13. E. Bacchiocchi & F. Montobbio, 2009. "Knowledge diffusion from university and public research. A comparison between US, Japan and Europe using patent citations," The Journal of Technology Transfer, Springer, vol. 34(2), pages 169-181, April.
    14. Ajay Agrawal & Rebecca Henderson, 2002. "Putting Patents in Context: Exploring Knowledge Transfer from MIT," Management Science, INFORMS, vol. 48(1), pages 44-60, January.
    15. Marie C. Thursby & Jerry Thursby & Swasti Gupta-Mukherjee, 2007. "Are There Real Effects of Licensing on Academic Research? A Life Cycle View," NBER Chapters, in: Academic Science and Entrepreneurship: Dual Engines of Growth, National Bureau of Economic Research, Inc.
    16. Anonymous, 1962. "Economic and Social Council," International Organization, Cambridge University Press, vol. 16(1), pages 195-216, January.
    17. Kenneth Arrow, 1962. "Economic Welfare and the Allocation of Resources for Invention," NBER Chapters, in: The Rate and Direction of Inventive Activity: Economic and Social Factors, pages 609-626, National Bureau of Economic Research, Inc.
    18. Fiona Murray & Siobhán O'Mahony, 2007. "Exploring the Foundations of Cumulative Innovation: Implications for Organization Science," Organization Science, INFORMS, vol. 18(6), pages 1006-1021, December.
    19. John Rigby, 2013. "Looking for the impact of peer review: does count of funding acknowledgements really predict research impact?," Scientometrics, Springer;Akadémiai Kiadó, vol. 94(1), pages 57-73, January.
    20. Fabrizio, Kira R. & Di Minin, Alberto, 2008. "Commercializing the laboratory: Faculty patenting and the open science environment," Research Policy, Elsevier, vol. 37(5), pages 914-931, June.
    21. Waltman, Ludo & van Eck, Nees Jan & van Leeuwen, Thed N. & Visser, Martijn S., 2013. "Some modifications to the SNIP journal impact indicator," Journal of Informetrics, Elsevier, vol. 7(2), pages 272-285.
    22. Dangzhi Zhao, 2010. "Characteristics and impact of grant-funded research: a case study of the library and information science field," Scientometrics, Springer;Akadémiai Kiadó, vol. 84(2), pages 293-306, August.
    23. Murray, Fiona & Stern, Scott, 2007. "Do formal intellectual property rights hinder the free flow of scientific knowledge?: An empirical test of the anti-commons hypothesis," Journal of Economic Behavior & Organization, Elsevier, vol. 63(4), pages 648-687, August.
    24. Fiona E. Murray & Scott Stern, 2007. "Do Formal Intellectual Property Rights Hinder the Free Flow of Scientific Knowledge?: An Empirical Test of the Anti-Commons Hypothesis," NBER Chapters, in: Academic Science and Entrepreneurship: Dual Engines of Growth, National Bureau of Economic Research, Inc.
    25. Jerry G. Thursby & Marie C. Thursby, 2002. "Who Is Selling the Ivory Tower? Sources of Growth in University Licensing," Management Science, INFORMS, vol. 48(1), pages 90-104, January.
    26. Anonymous, 1962. "Economic and Social Council," International Organization, Cambridge University Press, vol. 16(4), pages 835-844, October.
    Full references (including those not matched with items on IDEAS)

    Citations

    Citations are extracted by the CitEc Project, subscribe to its RSS feed for this item.
    as


    Cited by:

    1. Li, Xin & Tang, Xuli & Cheng, Qikai, 2022. "Predicting the clinical citation count of biomedical papers using multilayer perceptron neural network," Journal of Informetrics, Elsevier, vol. 16(4).
    2. Dzieżyc, Maciej & Kazienko, Przemysław, 2022. "Effectiveness of research grants funded by European Research Council and Polish National Science Centre," Journal of Informetrics, Elsevier, vol. 16(1).
    3. David B. Audretsch & Albert N. Link & Martijn Hasselt, 2019. "Knowledge begets knowledge: university knowledge spillovers and the output of scientific papers from U.S. Small Business Innovation Research (SBIR) projects," Scientometrics, Springer;Akadémiai Kiadó, vol. 121(3), pages 1367-1383, December.
    4. Paul Siu Fai Yip & Yunyu Xiao & Clifford Long Hin Wong & Terry Kit Fong Au, 2020. "Is there gender bias in research grant success in social sciences?: Hong Kong as a case study," Palgrave Communications, Palgrave Macmillan, vol. 7(1), pages 1-10, December.
    5. Munari, Federico & Toschi, Laura, 2021. "The impact of public funding on science valorisation: an analysis of the ERC Proof-of-Concept Programme," Research Policy, Elsevier, vol. 50(6).
    6. Shen, Hongquan & Xie, Juan & Ao, Weiyi & Cheng, Ying, 2022. "The continuity and citation impact of scientific collaboration with different gender composition," Journal of Informetrics, Elsevier, vol. 16(1).

    Most related items

    These are the items that most often cite the same works as this one and are cited by the same works as this one.
    1. Pluvia Zuniga, 2011. "The State of Patenting at Research Institutions in Developing Countries: Policy Approaches and Practices," WIPO Economic Research Working Papers 04, World Intellectual Property Organization - Economics and Statistics Division, revised Dec 2011.
    2. repec:wip:wpaper:4 is not listed on IDEAS
    3. Magerman, Tom & Looy, Bart Van & Debackere, Koenraad, 2015. "Does involvement in patenting jeopardize one’s academic footprint? An analysis of patent-paper pairs in biotechnology," Research Policy, Elsevier, vol. 44(9), pages 1702-1713.
    4. Andrew J. Nelson, 2016. "How to Share “A Really Good Secret”: Managing Sharing/Secrecy Tensions Around Scientific Knowledge Disclosure," Organization Science, INFORMS, vol. 27(2), pages 265-285, April.
    5. Francesco Lissoni, 2013. "Intellectual property and university–industry technology transfer," Chapters, in: Faïz Gallouj & Luis Rubalcaba & Paul Windrum (ed.), Public–Private Innovation Networks in Services, chapter 7, pages 164-194, Edward Elgar Publishing.
    6. Banal-Estañol, Albert & Jofre-Bonet, Mireia & Lawson, Cornelia, 2015. "The double-edged sword of industry collaboration: Evidence from engineering academics in the UK," Research Policy, Elsevier, vol. 44(6), pages 1160-1175.
    7. Larsen, Maria Theresa, 2011. "The implications of academic enterprise for public science: An overview of the empirical evidence," Research Policy, Elsevier, vol. 40(1), pages 6-19, February.
    8. Cornelia Lawson, 2013. "Academic patenting: the importance of industry support," The Journal of Technology Transfer, Springer, vol. 38(4), pages 509-535, August.
    9. Foray, Dominique & Lissoni, Francesco, 2010. "University Research and Public–Private Interaction," Handbook of the Economics of Innovation, in: Bronwyn H. Hall & Nathan Rosenberg (ed.), Handbook of the Economics of Innovation, edition 1, volume 1, chapter 0, pages 275-314, Elsevier.
    10. Francesco Lissoni & Fabio Montobbio, 2015. "The Ownership of Academic Patents and Their Impact. Evidence from Five European Countries," Revue économique, Presses de Sciences-Po, vol. 66(1), pages 143-171.
    11. Walter, Sascha G. & Schmidt, Arne & Walter, Achim, 2016. "Patenting rationales of academic entrepreneurs in weak and strong organizational regimes," Research Policy, Elsevier, vol. 45(2), pages 533-545.
    12. Burhan, Muqbil & Singh, Anil K. & Jain, Sudhir K., 2017. "Patents as proxy for measuring innovations: A case of changing patent filing behavior in Indian public funded research organizations," Technological Forecasting and Social Change, Elsevier, vol. 123(C), pages 181-190.
    13. Albert Banal-Estañol & Mireia Jofre-Bonet & Cornelia Meissner, 2008. "Theimpact of industry collaboration on research: Evidence from engineering academics in the UK," Economics Working Papers 1190, Department of Economics and Business, Universitat Pompeu Fabra, revised Aug 2010.
    14. Ani Gerbin & Mateja Drnovsek, 2016. "Determinants and public policy implications of academic-industry knowledge transfer in life sciences: a review and a conceptual framework," The Journal of Technology Transfer, Springer, vol. 41(5), pages 979-1076, October.
    15. Amit Shovon Ray & Sabyasachi Saha, "undated". "Patenting Public-Funded Research for Technology Transfer: A Conceptual-Empirical Synthesis of US Evidence and Lessons for India," Indian Council for Research on International Economic Relations, New Delhi Working Papers 244, Indian Council for Research on International Economic Relations, New Delhi, India.
    16. Aldo Geuna & Alessandro Muscio, 2008. "The governance of University knowledge transfer," SPRU Working Paper Series 173, SPRU - Science Policy Research Unit, University of Sussex Business School.
    17. Bryan, Kevin A. & Ozcan, Yasin & Sampat, Bhaven, 2020. "In-text patent citations: A user's guide," Research Policy, Elsevier, vol. 49(4).
    18. Philippe Aghion & Stefan Bechtold & Lea Cassar & Holger Herz, 2018. "The Causal Effects of Competition on Innovation: Experimental Evidence," The Journal of Law, Economics, and Organization, Oxford University Press, vol. 34(2), pages 162-195.
    19. Perkmann, Markus & Tartari, Valentina & McKelvey, Maureen & Autio, Erkko & Broström, Anders & D’Este, Pablo & Fini, Riccardo & Geuna, Aldo & Grimaldi, Rosa & Hughes, Alan & Krabel, Stefan & Kitson, Mi, 2013. "Academic engagement and commercialisation: A review of the literature on university–industry relations," Research Policy, Elsevier, vol. 42(2), pages 423-442.
    20. Laurent R Bergé & Thorsten Doherr & Katrin Hussinger, 2023. "How patent rights affect university science," Industrial and Corporate Change, Oxford University Press and the Associazione ICC, vol. 32(3), pages 673-699.
    21. Michaël Bikard & Keyvan Vakili & Florenta Teodoridis, 2019. "When Collaboration Bridges Institutions: The Impact of University–Industry Collaboration on Academic Productivity," Organization Science, INFORMS, vol. 30(2), pages 426-445, March.

    Corrections

    All material on this site has been provided by the respective publishers and authors. You can help correct errors and omissions. When requesting a correction, please mention this item's handle: RePEc:spr:scient:v:117:y:2018:i:1:d:10.1007_s11192-018-2846-z. See general information about how to correct material in RePEc.

    If you have authored this item and are not yet registered with RePEc, we encourage you to do it here. This allows to link your profile to this item. It also allows you to accept potential citations to this item that we are uncertain about.

    If CitEc recognized a bibliographic reference but did not link an item in RePEc to it, you can help with this form .

    If you know of missing items citing this one, you can help us creating those links by adding the relevant references in the same way as above, for each refering item. If you are a registered author of this item, you may also want to check the "citations" tab in your RePEc Author Service profile, as there may be some citations waiting for confirmation.

    For technical questions regarding this item, or to correct its authors, title, abstract, bibliographic or download information, contact: Sonal Shukla or Springer Nature Abstracting and Indexing (email available below). General contact details of provider: http://www.springer.com .

    Please note that corrections may take a couple of weeks to filter through the various RePEc services.

    IDEAS is a RePEc service. RePEc uses bibliographic data supplied by the respective publishers.