IDEAS home Printed from https://ideas.repec.org/a/spr/pharme/v23y2005i10p995-1006.html
   My bibliography  Save this article

Pharmacological management of overactive bladder

Author

Listed:
  • Denis Getsios
  • Wissam El-Hadi
  • Ingrid Caro
  • J. Caro

Abstract

Overactive bladder is a common condition, with recent findings estimating the prevalence in adults at about 15%. Symptoms, including urinary urgency, high voiding frequency and urge incontinence, have been shown to decrease patients’ quality of life. Given its high prevalence, the economic burden of overactive bladder is also substantial, with a recent estimate placing the annual cost in the US at $US9.1 billion (year 2000 values). The objective of this review is to provide a critical appraisal of published economic evaluations of pharmacological and non-pharmacological treatments for overactive bladder. Published economic evaluations of treatments for overactive bladder have focused entirely on pharmacological treatments — mainly on the two most commonly used drugs, oxybutynin and tolterodine, each of which is available in immediate- and extended-release formulations. Ten economic evaluations (more than half are cost-effectiveness studies) have been published. Modelling with decision trees or Markov models has been the predominant method. Evaluations comparing drug therapy with no treatment have concluded that drug therapy is cost effective. Analyses comparing the formulations of oxybutynin and tolterodine have produced highly inconsistent results, largely due to the sources of data employed for effectiveness and treatment discontinuation rates. There are no evaluations of drugs relative to non-pharmacological treatment, and there are other significant gaps in the economic evaluations of treatment to date. These include gaps resulting from a lack of reliable data on the performance of these drugs in real-world settings, particularly data on long-term persistence with treatment. A more definitive pharmacoeconomic comparison of oxybutynin and tolterodine formulations, incorporating all available clinical data, and other treatment options would help direct treatment. Copyright Adis Data Information BV 2005

Suggested Citation

  • Denis Getsios & Wissam El-Hadi & Ingrid Caro & J. Caro, 2005. "Pharmacological management of overactive bladder," PharmacoEconomics, Springer, vol. 23(10), pages 995-1006, October.
    • Handle: RePEc:spr:pharme:v:23:y:2005:i:10:p:995-1006
    DOI: 10.2165/00019053-200523100-00003
    as

    Download full text from publisher

    File URL: http://hdl.handle.net/10.2165/00019053-200523100-00003
    Download Restriction: Access to full text is restricted to subscribers.
    File URL: https://libkey.io/10.2165/00019053-200523100-00003?utm_source=ideas
    LibKey link: if access is restricted and if your library uses this service, LibKey will redirect you to where you can use your library subscription to access this item
    ---><---

    As the access to this document is restricted, you may want to search for a different version of it.

    References listed on IDEAS

    as
    1. James P. Johnson & M. Audrey Korsgaard & Harry J. Sapienza, 2002. "Abstract," Strategic Management Journal, Wiley Blackwell, vol. 23(12), pages 1141-1160, December.
    Full references (including those not matched with items on IDEAS)

    Most related items

    These are the items that most often cite the same works as this one and are cited by the same works as this one.
    1. Tariq Shah & Syed Akhter Hussain Shah & Eatzaz Ahmed, 2010. "Algebraic Representation of Social Capital Matrix," Microeconomics Working Papers 22724, East Asian Bureau of Economic Research.
    2. Joanna Bryson, 2008. "Embodiment versus memetics," Mind & Society: Cognitive Studies in Economics and Social Sciences, Springer;Fondazione Rosselli, vol. 7(1), pages 77-94, June.
    3. Shah, Syed Akhter Hussain & Shah, Tariq & Ahmad, Eatzaz, 2011. "Equilibrium in Economic Development A Perspective of Social Capital," MPRA Paper 59294, University Library of Munich, Germany.
    4. LEOVARIDIS, Cristina, 2013. "Aspects Of Innovation Within Romanian Enterprises, Compared To Other European Countries," Annals of Spiru Haret University, Economic Series, Universitatea Spiru Haret, vol. 4(1), pages 23-34.
    5. Michalak, Katja, 2011. "Can Lipset’s theory travel through time and space? the destination Nicaragua, 1972-1998. A time series test of the social requisites of democracy," MPRA Paper 31903, University Library of Munich, Germany.
    6. Barham, Bradford L. & Foltz, Jeremy D., 2007. "Patenting, Commercialization, and US Academic Research in the 21st Century: The Resilience of Basic, Federally-Funded Open Science," Staff Paper Series 513, University of Wisconsin, Agricultural and Applied Economics.
    7. Giessner, S.R. & Schubert, T.W., 2007. "High in the Hierarchy: How Vertical Location and Judgments of Leaders' Power are Interrelated," ERIM Report Series Research in Management ERS-2007-021-ORG, Erasmus Research Institute of Management (ERIM), ERIM is the joint research institute of the Rotterdam School of Management, Erasmus University and the Erasmus School of Economics (ESE) at Erasmus University Rotterdam.
    8. Shah, Syed Akhter Hussain & Shah, Tari shah & Ahmed, Eatzaz, 2011. "Top-Down Approach for the Social Capital Development," MPRA Paper 59293, University Library of Munich, Germany.
    9. David Smith & Jianguo Chen & Hamish Anderson, 2012. "The relationship between capital structure and product markets: evidence from New Zealand," Review of Quantitative Finance and Accounting, Springer, vol. 38(1), pages 1-24, January.
    10. Melanie Morten, 2006. "Indian Poverty during the 1990s: Resolving Methodological Issues from the 55th NSS Round," ASARC Working Papers 2006-07, The Australian National University, Australia South Asia Research Centre.
    11. Anita Gill, 2006. "Interlinked Agrarian Credit Markets in a Developing Economy: A Case Study of Indian Punjab," Working Papers id:760, eSocialSciences.
    12. Ahmed, Ahmed Yibrie & Mihiretie, Dawit Mekonnen, 2015. "Primary school teachers and parents’ views on automatic promotion practices and its implications for education quality," International Journal of Educational Development, Elsevier, vol. 43(C), pages 90-99.
    13. De Valois, Karen K. & Takeuchi, Tatsuto & Disch, Michael, 2003. "Judging the Speed of Pedestrians and Bicycles at Night," University of California Transportation Center, Working Papers qt5xw4s6z8, University of California Transportation Center.
    14. Giessner, Steffen R. & Schubert, Thomas W., 2007. "High in the hierarchy: How vertical location and judgments of leaders' power are interrelated," Organizational Behavior and Human Decision Processes, Elsevier, vol. 104(1), pages 30-44, September.
    15. Theofanis Karagiorgos, 2010. "Corporate Social Responsibility and Financial Performance: An Empirical Analysis on Greek Companies," European Research Studies Journal, European Research Studies Journal, vol. 0(4), pages 85-108.
    16. Piotr Szymański, 2012. "Problems in business valuation –analysis of survey results," Romanian Economic Journal, Department of International Business and Economics from the Academy of Economic Studies Bucharest, vol. 15(44), pages 137-162, June.
    17. Kheshgi, Haroon S, 2004. "Evasion of CO2 injected into the ocean in the context of CO2 stabilization," Energy, Elsevier, vol. 29(9), pages 1479-1486.

    More about this item

    Statistics

    Access and download statistics

    Corrections

    All material on this site has been provided by the respective publishers and authors. You can help correct errors and omissions. When requesting a correction, please mention this item's handle: RePEc:spr:pharme:v:23:y:2005:i:10:p:995-1006. See general information about how to correct material in RePEc.

    If you have authored this item and are not yet registered with RePEc, we encourage you to do it here. This allows to link your profile to this item. It also allows you to accept potential citations to this item that we are uncertain about.

    If CitEc recognized a bibliographic reference but did not link an item in RePEc to it, you can help with this form .

    If you know of missing items citing this one, you can help us creating those links by adding the relevant references in the same way as above, for each refering item. If you are a registered author of this item, you may also want to check the "citations" tab in your RePEc Author Service profile, as there may be some citations waiting for confirmation.

    For technical questions regarding this item, or to correct its authors, title, abstract, bibliographic or download information, contact: Sonal Shukla or Springer Nature Abstracting and Indexing (email available below). General contact details of provider: http://www.springer.com .

    Please note that corrections may take a couple of weeks to filter through the various RePEc services.

    IDEAS is a RePEc service. RePEc uses bibliographic data supplied by the respective publishers.