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State-of-the-art review of neural network applications in pharmaceutical manufacturing: current state and future directions

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  • Elnaz Gholipour

    (Eastern Mediterranean University)

  • Ali Bastas

    (Eastern Mediterranean University)

Abstract

Neural network applications, as an emerging machine learning technology, are increasingly being integrated into pharmaceutical manufacturing technologies, offering significant improvement opportunities for performance, efficiency and sustainability. This review paper utilizes a systematic methodology to establish key literature trends and themes. The state-of-the-art body of knowledge in this hot research area is analyzed in descriptive (e.g. neural network technologies studied, sustainability indicators considered, manufacturing process addressed) and thematic synthesis components. Process analysis and improvement, quality control and additive manufacturing were identified as the three focal research themes, and research lines within these themes were further studied and discussed. To guide future research, potential paths and research questions are proposed against the gaps identified. The originality of this work lies in its methodology (adoption of a systematic review approach, highly limited in the current literature), its inclusion of sustainability (as an imperative concept for manufacturing technology research) and its specific focus on neural network applications in the context of pharmaceutical manufacturing technologies (a perspective, either has been missing or addressed too widely by extant contributions). Graphical abstract

Suggested Citation

  • Elnaz Gholipour & Ali Bastas, 2024. "State-of-the-art review of neural network applications in pharmaceutical manufacturing: current state and future directions," Journal of Intelligent Manufacturing, Springer, vol. 35(7), pages 3003-3035, October.
    • Handle: RePEc:spr:joinma:v:35:y:2024:i:7:d:10.1007_s10845-023-02206-0
    DOI: 10.1007/s10845-023-02206-0
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    References listed on IDEAS

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    1. David Moher & Alessandro Liberati & Jennifer Tetzlaff & Douglas G Altman & The PRISMA Group, 2009. "Preferred Reporting Items for Systematic Reviews and Meta-Analyses: The PRISMA Statement," PLOS Medicine, Public Library of Science, vol. 6(7), pages 1-6, July.
    2. Ali Bastas, 2021. "Sustainable Manufacturing Technologies: A Systematic Review of Latest Trends and Themes," Sustainability, MDPI, vol. 13(8), pages 1-22, April.
    3. Nigel Yee, 2016. "Principal Component Selection for Neural Network Classification of Active Ingredients from Near Infrared Spectra," The Review of Socionetwork Strategies, Springer, vol. 10(2), pages 91-103, December.
    4. Martina K Linnenluecke & Mauricio Marrone & Abhay K Singh, 2020. "Conducting systematic literature reviews and bibliometric analyses," Australian Journal of Management, Australian School of Business, vol. 45(2), pages 175-194, May.
    5. Prateek Saxena & Panagiotis Stavropoulos & John Kechagias & Konstantinos Salonitis, 2020. "Sustainability Assessment for Manufacturing Operations," Energies, MDPI, vol. 13(11), pages 1-19, May.
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