IDEAS home Printed from https://ideas.repec.org/a/plo/pone00/0156051.html
   My bibliography  Save this article

Increased Mortality in Metal-on-Metal versus Non-Metal-on-Metal Primary Total Hip Arthroplasty at 10 Years and Longer Follow-Up: A Systematic Review and Meta-Analysis

Author

Listed:
  • B G Pijls
  • J M T A Meessen
  • J W Schoones
  • M Fiocco
  • H J L van der Heide
  • A Sedrakyan
  • R G H H Nelissen

Abstract

Importance: There are concerns about increased mortality in patients with metal-on-metal bearings in total hip arthroplasty (THA). Objective: To determine the mortality and the morbidity in patients with metal-on-metal articulations (MOM THA) compared to patients with non-metal-on-metal articulations (non-MOM THA) after primary total hip arthroplasty. Data Sources: Search of PubMed, MEDLINE, EMBASE, Web of Science, Cochrane, CINAHL, AcademicSearchPremier, ScienceDirect, Wiley and clinical trial registers through March 2015, augmented by a hand search of references from the included articles. No language restrictions were applied. Study Selection: Two reviewers screened and identified randomised controlled trials and observational studies of primary total hip arthroplasty comparing MOM THA with non-MOM THA. Data Extraction and Synthesis: Two reviewers independently extracted study data and assessed risk of bias. Risk differences (RD) were calculated with random effect models. Meta-regression was used to explore modifying factors. Main Outcomes and Measures: Difference in mortality and difference in morbidity expressed as revisions and medical complications between patients with MOM THA and non-MOM THA. Results: Forty-seven studies were included, comprising 4,000 THA in randomised trials and over 500,000 THA in observational studies. For mortality, random effects analysis revealed a higher pooled RD of 0.7%, 95%, confidence interval (CI) [0.0%, 2.3%], I-square 42%; the heterogeneity was explained by differences in follow-up. When restricted to studies with long term follow-up (i.e. 10 years or more), the RD for mortality was 8.5%, 95%, CI [5.8%, 11.2%]; number needed to treat was 12. Further subgroup analyses and meta-regression random effects models revealed no evidence for other moderator variables (study level covariates, e.g. resurfacing vs. non-resurfacing MOM) than follow-up duration. The quality of the evidence presented in this meta-analysis was characterized as moderate according to the CLEAR-NPT (for non-pharmacological trials) and Cochrane risk of bias Table. Conclusions and Relevance: Meta-analysis suggests there may be an increased long-term risk of mortality and revision surgery for patients with MOM THA compared to patients with non-MOM THA. Registration: PROSPERO 2014:CRD42014007417

Suggested Citation

  • B G Pijls & J M T A Meessen & J W Schoones & M Fiocco & H J L van der Heide & A Sedrakyan & R G H H Nelissen, 2016. "Increased Mortality in Metal-on-Metal versus Non-Metal-on-Metal Primary Total Hip Arthroplasty at 10 Years and Longer Follow-Up: A Systematic Review and Meta-Analysis," PLOS ONE, Public Library of Science, vol. 11(6), pages 1-17, June.
  • Handle: RePEc:plo:pone00:0156051
    DOI: 10.1371/journal.pone.0156051
    as

    Download full text from publisher

    File URL: https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0156051
    Download Restriction: no

    File URL: https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0156051&type=printable
    Download Restriction: no

    File URL: https://libkey.io/10.1371/journal.pone.0156051?utm_source=ideas
    LibKey link: if access is restricted and if your library uses this service, LibKey will redirect you to where you can use your library subscription to access this item
    ---><---

    References listed on IDEAS

    as
    1. Viechtbauer, Wolfgang, 2010. "Conducting Meta-Analyses in R with the metafor Package," Journal of Statistical Software, Foundation for Open Access Statistics, vol. 36(i03).
    2. David Moher & Alessandro Liberati & Jennifer Tetzlaff & Douglas G Altman & The PRISMA Group, 2009. "Preferred Reporting Items for Systematic Reviews and Meta-Analyses: The PRISMA Statement," PLOS Medicine, Public Library of Science, vol. 6(7), pages 1-6, July.
    Full references (including those not matched with items on IDEAS)

    Most related items

    These are the items that most often cite the same works as this one and are cited by the same works as this one.
    1. Piers Steel & Sjoerd Beugelsdijk & Herman Aguinis, 2021. "The anatomy of an award-winning meta-analysis: Recommendations for authors, reviewers, and readers of meta-analytic reviews," Journal of International Business Studies, Palgrave Macmillan;Academy of International Business, vol. 52(1), pages 23-44, February.
    2. Mahesh Shumsher Rughooputh & Rui Zeng & Ying Yao, 2015. "Protein Diet Restriction Slows Chronic Kidney Disease Progression in Non-Diabetic and in Type 1 Diabetic Patients, but Not in Type 2 Diabetic Patients: A Meta-Analysis of Randomized Controlled Trials ," PLOS ONE, Public Library of Science, vol. 10(12), pages 1-17, December.
    3. Christopher Winchester & Kelsey E. Medeiros, 2023. "In Bounds but Out of the Box: A Meta-Analysis Clarifying the Effect of Ethicality on Creativity," Journal of Business Ethics, Springer, vol. 183(3), pages 713-743, March.
    4. Kelly R Moran & Sara Y Del Valle, 2016. "A Meta-Analysis of the Association between Gender and Protective Behaviors in Response to Respiratory Epidemics and Pandemics," PLOS ONE, Public Library of Science, vol. 11(10), pages 1-25, October.
    5. Sandra Feijóo & Raquel Rodríguez-Fernández, 2021. "A Meta-Analytical Review of Gender-Based School Bullying in Spain," IJERPH, MDPI, vol. 18(23), pages 1-13, December.
    6. Xizheng Xu & Zhiqiang Liu & Shaoying Gong & Yunpeng Wu, 2022. "The Relationship between Empathy and Attachment in Children and Adolescents: Three-Level Meta-Analyses," IJERPH, MDPI, vol. 19(3), pages 1-18, January.
    7. Kathrin Wunsch & Janis Fiedler & Philip Bachert & Alexander Woll, 2021. "The Tridirectional Relationship among Physical Activity, Stress, and Academic Performance in University Students: A Systematic Review and Meta-Analysis," IJERPH, MDPI, vol. 18(2), pages 1-18, January.
    8. Alan da Silveira Fleck & Margaux L. Sadoine & Stéphane Buteau & Eva Suarthana & Maximilien Debia & Audrey Smargiassi, 2021. "Environmental and Occupational Short-Term Exposure to Airborne Particles and FEV 1 and FVC in Healthy Adults: A Systematic Review and Meta-Analysis," IJERPH, MDPI, vol. 18(20), pages 1-19, October.
    9. Evangelos Danopoulos & Maureen Twiddy & Jeanette M Rotchell, 2020. "Microplastic contamination of drinking water: A systematic review," PLOS ONE, Public Library of Science, vol. 15(7), pages 1-23, July.
    10. Claudia Menne-Lothmann & Wolfgang Viechtbauer & Petra Höhn & Zuzana Kasanova & Simone P Haller & Marjan Drukker & Jim van Os & Marieke Wichers & Jennifer Y F Lau, 2014. "How to Boost Positive Interpretations? A Meta-Analysis of the Effectiveness of Cognitive Bias Modification for Interpretation," PLOS ONE, Public Library of Science, vol. 9(6), pages 1-26, June.
    11. José Felipe Orzuna-Orzuna & Juan Eduardo Godina-Rodríguez & Jonathan Raúl Garay-Martínez & Guillermo Reséndiz-González & Santiago Joaquín-Cancino & Alejandro Lara-Bueno, 2024. "Milk Yield, Composition, and Fatty Acid Profile in Milk of Dairy Cows Supplemented with Microalgae Schizochytrium sp.: A Meta-Analysis," Agriculture, MDPI, vol. 14(7), pages 1-13, July.
    12. Wei-Cheng Chang & Chin Lin & Cho-Hao Lee & Tzu-Ling Sung & Tao-Hsin Tung & Jorn-Hon Liu, 2017. "Vitrectomy with or without internal limiting membrane peeling for idiopathic epiretinal membrane: A meta-analysis," PLOS ONE, Public Library of Science, vol. 12(6), pages 1-18, June.
    13. Christopher Hansen & Holger Steinmetz & Jörn Block, 2022. "How to conduct a meta-analysis in eight steps: a practical guide," Management Review Quarterly, Springer, vol. 72(1), pages 1-19, February.
    14. Shaylea Badovinac & Jodi Martin & Camille Guérin-Marion & Monica O’Neill & Rebecca Pillai Riddell & Jean-François Bureau & Rebecca Spiegel, 2018. "Associations between mother-preschooler attachment and maternal depression symptoms: A systematic review and meta-analysis," PLOS ONE, Public Library of Science, vol. 13(10), pages 1-27, October.
    15. Fazel, Seena & Burghart, Matthias & Fanshawe, Thomas & Gil, Sharon Danielle & Monahan, John & Yu, Rongqin, 2022. "The predictive performance of criminal risk assessment tools used at sentencing: Systematic review of validation studies," Journal of Criminal Justice, Elsevier, vol. 81(C).
    16. Amro Qaddoura & Payam Yazdan-Ashoori & Conrad Kabali & Lehana Thabane & R Brian Haynes & Stuart J Connolly & Harriette Gillian Christine Van Spall, 2015. "Efficacy of Hospital at Home in Patients with Heart Failure: A Systematic Review and Meta-Analysis," PLOS ONE, Public Library of Science, vol. 10(6), pages 1-15, June.
    17. Boshra H. Namin & Torvald Øgaard & Jo Røislien, 2021. "Workplace Incivility and Turnover Intention in Organizations: A Meta-Analytic Review," IJERPH, MDPI, vol. 19(1), pages 1-19, December.
    18. Ruohuang Jiao & Wojtek Przepiorka & Vincent Buskens, 2022. "Moderators of reputation effects in peer-to-peer online markets: a meta-analytic model selection approach," Journal of Computational Social Science, Springer, vol. 5(1), pages 1041-1067, May.
    19. Pedro Silva Moreira & Pedro R Almeida & Hugo Leite-Almeida & Nuno Sousa & Patrício Costa, 2016. "Impact of Chronic Stress Protocols in Learning and Memory in Rodents: Systematic Review and Meta-Analysis," PLOS ONE, Public Library of Science, vol. 11(9), pages 1-24, September.
    20. Romain Cadario & Pierre Chandon, 2020. "Which Healthy Eating Nudges Work Best? A Meta-Analysis of Field Experiments," Marketing Science, INFORMS, vol. 39(3), pages 465-486, May.

    More about this item

    Statistics

    Access and download statistics

    Corrections

    All material on this site has been provided by the respective publishers and authors. You can help correct errors and omissions. When requesting a correction, please mention this item's handle: RePEc:plo:pone00:0156051. See general information about how to correct material in RePEc.

    If you have authored this item and are not yet registered with RePEc, we encourage you to do it here. This allows to link your profile to this item. It also allows you to accept potential citations to this item that we are uncertain about.

    If CitEc recognized a bibliographic reference but did not link an item in RePEc to it, you can help with this form .

    If you know of missing items citing this one, you can help us creating those links by adding the relevant references in the same way as above, for each refering item. If you are a registered author of this item, you may also want to check the "citations" tab in your RePEc Author Service profile, as there may be some citations waiting for confirmation.

    For technical questions regarding this item, or to correct its authors, title, abstract, bibliographic or download information, contact: plosone (email available below). General contact details of provider: https://journals.plos.org/plosone/ .

    Please note that corrections may take a couple of weeks to filter through the various RePEc services.

    IDEAS is a RePEc service. RePEc uses bibliographic data supplied by the respective publishers.