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JMFit: A SAS Macro for Joint Models of Longitudinal and Survival Data

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  • Zhang, Danjie
  • Chen, Ming-Hui
  • Ibrahim, Joseph G.
  • Boye, Mark E.
  • Shen, Wei

Abstract

Joint models for longitudinal and survival data now have a long history of being used in clinical trials or other studies in which the goal is to assess a treatment effect while accounting for a longitudinal biomarker such as patient-reported outcomes or immune responses. Although software has been developed for fitting the joint model, no software packages are currently available for simultaneously fitting the joint model and assessing the fit of the longitudinal component and the survival component of the model separately as well as the contribution of the longitudinal data to the fit of the survival model. To fulfill this need, we develop a SAS macro, called JMFit. JMFit implements a variety of popular joint models and provides several model assessment measures including the decomposition of AIC and BIC as well as ∆AIC and ∆BIC recently developed in Zhang, Chen, Ibrahim, Boye, Wang, and Shen (2014). Examples with real and simulated data are provided to illustrate the use of JMFit.

Suggested Citation

  • Zhang, Danjie & Chen, Ming-Hui & Ibrahim, Joseph G. & Boye, Mark E. & Shen, Wei, 2016. "JMFit: A SAS Macro for Joint Models of Longitudinal and Survival Data," Journal of Statistical Software, Foundation for Open Access Statistics, vol. 71(i03).
  • Handle: RePEc:jss:jstsof:v:071:i03
    DOI: http://hdl.handle.net/10.18637/jss.v071.i03
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    References listed on IDEAS

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    1. Rizopoulos, Dimitris, 2016. "The R Package JMbayes for Fitting Joint Models for Longitudinal and Time-to-Event Data Using MCMC," Journal of Statistical Software, Foundation for Open Access Statistics, vol. 72(i07).
    2. Yueh-Yun Chi & Joseph G. Ibrahim, 2006. "Joint Models for Multivariate Longitudinal and Multivariate Survival Data," Biometrics, The International Biometric Society, vol. 62(2), pages 432-445, June.
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    Cited by:

    1. Jiawei Xu & Matthew A. Psioda & Joseph G. Ibrahim, 2023. "Bayesian Design of Clinical Trials Using Joint Cure Rate Models for Longitudinal and Time-to-Event Data," Lifetime Data Analysis: An International Journal Devoted to Statistical Methods and Applications for Time-to-Event Data, Springer, vol. 29(1), pages 213-233, January.

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