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Associations of Cognitive Complaints and Depressive Symptoms with Health-Related Quality of Life and Perceived Overall Health in Japanese Adult Volunteers

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  • Kuniyoshi Toyoshima

    (Department of Psychiatry, Hokkaido University Graduate School of Medicine, Sapporo 060-8638, Japan)

  • Takeshi Inoue

    (Department of Psychiatry, Tokyo Medical University, Tokyo 160-0023, Japan)

  • Toshiaki Baba

    (Bureau of International Health Cooperation, National Center for Global Health and Medicine, Tokyo 162-8655, Japan)

  • Jiro Masuya

    (Department of Psychiatry, Tokyo Medical University, Tokyo 160-0023, Japan)

  • Masahiko Ichiki

    (Department of Psychiatry, Tokyo Medical University, Tokyo 160-0023, Japan)

  • Yota Fujimura

    (Department of Psychiatry, Tokyo Medical University, Tokyo 160-0023, Japan)

  • Ichiro Kusumi

    (Department of Psychiatry, Hokkaido University Graduate School of Medicine, Sapporo 060-8638, Japan)

Abstract

Cognitive complaints, defined as perceived cognitive dysfunction in daily living, are associated with depressive symptoms. The associations of cognitive complaints and depressive symptoms with health-related quality of life (HRQoL) and perceived overall health in Japanese adults remains unknown. To investigate these relationships, we evaluated a convenience sample of 525 Japanese adult volunteers (Mage: 41.3 ± 11.7; 238 male and 287 female). We used the Cognitive Complaints in Bipolar Disorder Rating Assessment (evaluating cognitive complaints), Patient Health Questionnaire-9 (evaluating depressive symptoms), EuroQol-5 Dimension-5 Level (EQ-5D-5L; evaluating HRQoL), and EuroQol-Visual Analogue Scale (EQ-VAS; evaluating perceived overall health). Our path analyses suggested that both cognitive complaints and depressive symptoms had significant total effects on HRQoL and perceived overall health. Furthermore, cognitive complaints were not significantly associated directly with HRQoL and perceived overall health, whereas cognitive complaints were significantly associated with HRQoL and perceived overall health indirectly via depressive symptoms. Depressive symptoms were significantly associated directly with HRQoL and perceived overall health. This study suggests that depressive symptoms may mediate the associations of cognitive complaints with HRQoL and perceived overall health. Thus, to address the HRQoL and perceived overall health associated with cognitive complaints, evaluation and intervention for depressive symptoms may be useful in public health.

Suggested Citation

  • Kuniyoshi Toyoshima & Takeshi Inoue & Toshiaki Baba & Jiro Masuya & Masahiko Ichiki & Yota Fujimura & Ichiro Kusumi, 2021. "Associations of Cognitive Complaints and Depressive Symptoms with Health-Related Quality of Life and Perceived Overall Health in Japanese Adult Volunteers," IJERPH, MDPI, vol. 18(18), pages 1-12, September.
    • Handle: RePEc:gam:jijerp:v:18:y:2021:i:18:p:9647-:d:634678
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