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Factors Associated with Mortality among Elderly People in the COVID-19 Pandemic (SARS-CoV-2): A Systematic Review and Meta-Analysis

Author

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  • Vicente Paulo Alves

    (Stricto Sensu Graduate Program in Gerontology/Medicine, University Catholic of de Brasília, Taguatinga 71966-700, Brazil
    Unit of Biostatistics, Epidemiology and Public Health, Padova University, 35122 Padova, Italy)

  • Francine Golghetto Casemiro

    (Ribeirão Preto School of Nursing, University of São Paulo, São Paulo 14040-902, Brazil)

  • Bruno Gedeon de Araujo

    (Stricto Sensu Graduate Program in Gerontology/Medicine, University Catholic of de Brasília, Taguatinga 71966-700, Brazil)

  • Marcos André de Souza Lima

    (Stricto Sensu Graduate Program in Gerontology/Medicine, University Catholic of de Brasília, Taguatinga 71966-700, Brazil)

  • Rayssa Silva de Oliveira

    (Stricto Sensu Graduate Program in Gerontology/Medicine, University Catholic of de Brasília, Taguatinga 71966-700, Brazil)

  • Fernanda Tamires de Souza Fernandes

    (Stricto Sensu Graduate Program in Gerontology/Medicine, University Catholic of de Brasília, Taguatinga 71966-700, Brazil)

  • Ana Vitória Campos Gomes

    (Stricto Sensu Graduate Program in Gerontology/Medicine, University Catholic of de Brasília, Taguatinga 71966-700, Brazil)

  • Dario Gregori

    (Unit of Biostatistics, Epidemiology and Public Health, Padova University, 35122 Padova, Italy)

Abstract

The objective of this meta-analysis was to evaluate the factors associated with the mortality of elderly Italians diagnosed with coronavirus who resided in institutions or who were hospitalized because of the disease. Methods: A systematic review following the recommendations of The Joanna Briggs Institute (JBI) was carried out, utilizing the PEO strategy, i.e., Population, Exposure and Outcome. In this case, the population was the elderly aged over 65 years old, the exposure referred to the SARS-CoV-2 pandemic and the outcome was mortality. The National Center for Biotechnology Information (NCBI/PubMed), Latin American and Caribbean Literature in Health Sciences (LILACS), Excerpta Medica Database (EMBASE) and Cumulative Index to Nursing and Allied Health Literature (CINAHL) databases were used until 31 July 2020. Results: Five Italian studies were included in this meta-analysis, with the number of elderly people included varying between 18 and 1591 patients. The main morbidities presented by the elderly in the studies were dementia, diabetes, chronic kidney disease and hypertension. Conclusions: The factors associated with the mortality of elderly Italian people diagnosed with SARS-CoV-2 who lived in institutions or who were hospitalized because of the disease were evaluated. It was found that dementia, diabetes, chronic kidney disease and hypertension were the main diagnosed diseases for mortality in elderly people with COVID-19.

Suggested Citation

  • Vicente Paulo Alves & Francine Golghetto Casemiro & Bruno Gedeon de Araujo & Marcos André de Souza Lima & Rayssa Silva de Oliveira & Fernanda Tamires de Souza Fernandes & Ana Vitória Campos Gomes & Da, 2021. "Factors Associated with Mortality among Elderly People in the COVID-19 Pandemic (SARS-CoV-2): A Systematic Review and Meta-Analysis," IJERPH, MDPI, vol. 18(15), pages 1-9, July.
    • Handle: RePEc:gam:jijerp:v:18:y:2021:i:15:p:8008-:d:603795
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    References listed on IDEAS

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    1. Giovanna Deiana & Antonio Azara & Marco Dettori & Fiorenzo Delogu & Gavino Vargiu & Isabella Gessa & Filippo Stroscio & Marcello Tidore & Giorgio Steri & Paolo Castiglia, 2020. "Deaths in SARS-Cov-2 Positive Patients in Italy: The Influence of Underlying Health Conditions on Lethality," IJERPH, MDPI, vol. 17(12), pages 1-10, June.
    2. David Moher & Alessandro Liberati & Jennifer Tetzlaff & Douglas G Altman & The PRISMA Group, 2009. "Preferred Reporting Items for Systematic Reviews and Meta-Analyses: The PRISMA Statement," PLOS Medicine, Public Library of Science, vol. 6(7), pages 1-6, July.
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    1. Iulia Făgărășan & Adriana Rusu & Maria Cristea & Cornelia-Gabriela Bala & Damiana-Maria Vulturar & Ciprian Cristea & Doina-Adina Todea, 2022. "Predictors of New-Onset Diabetes in Hospitalized Patients with SARS-CoV-2 Infection," IJERPH, MDPI, vol. 19(20), pages 1-14, October.
    2. Mario J. Valladares-Garrido & Aldo Alvarez-Risco & Luis E. Vasquez-Elera & Christopher G. Valdiviezo-Morales & Raisa N. Martinez-Rivera & Annel L. Cruz-Zapata & César Johan Pereira-Victorio & Elian Ga, 2023. "Factors Associated with Mortality in Patients with COVID-19 from a Hospital in Northern Peru," Sustainability, MDPI, vol. 15(5), pages 1-14, February.

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