IDEAS home Printed from https://ideas.repec.org/a/gam/jijerp/v13y2016i12p1216-d84747.html
   My bibliography  Save this article

Estimation of Saliva Cotinine Cut-Off Points for Active and Passive Smoking during Pregnancy—Polish Mother and Child Cohort (REPRO_PL)

Author

Listed:
  • Kinga Polanska

    (Department of Environmental Epidemiology, Nofer Institute of Occupational Medicine, 91-348 Lodz, Poland)

  • Anna Krol

    (Department of Environmental Epidemiology, Nofer Institute of Occupational Medicine, 91-348 Lodz, Poland)

  • Pawel Kaluzny

    (Department of Environmental Epidemiology, Nofer Institute of Occupational Medicine, 91-348 Lodz, Poland)

  • Danuta Ligocka

    (Bureau of Quality Assurance, Nofer Institute of Occupational Medicine, 91-348 Lodz, Poland)

  • Karolina Mikolajewska

    (Department of Biological and Environmental Monitoring, Nofer Institute of Occupational Medicine, 91-348 Lodz, Poland)

  • Seif Shaheen

    (Centre for Primary Care and Public Health, Blizard Institute, Barts and the London School of Medicine and Dentistry, Queen Mary University of London, E1 2AB London, UK)

  • Robert Walton

    (Centre for Primary Care and Public Health, Blizard Institute, Barts and the London School of Medicine and Dentistry, Queen Mary University of London, E1 2AB London, UK)

  • Wojciech Hanke

    (Department of Environmental Epidemiology, Nofer Institute of Occupational Medicine, 91-348 Lodz, Poland)

Abstract

A reliable assessment of smoking status has significant public health implications and is essential for research purposes. The aim of this study was to determine optimal saliva cotinine cut-off values for smoking during pregnancy. The analyses were based on data from 1771 women from the Polish Mother and Child Cohort. Saliva cotinine concentrations were assessed by high performance liquid chromatography coupled with tandem mass spectrometry (HPLC-ESI + MS/MS). The saliva cotinine cut-off value for active smoking was established at 10 ng/mL (sensitivity 96%, specificity 95%) and for passive smoking at 1.5 ng/mL (sensitivity 63%, specificity 71%). About 5% of the self-reported non-smoking women were classified as smokers based on the cotinine cut-off value. Significantly more younger, single, and less educated self-reported non-smokers had a cotinine concentration higher than 10 ng/mL compared to those who were older, married, and who had a university degree. Close to 30% of the non-smokers who indicated that smoking was not allowed in their home could be classified as exposed to passive smoking based on the cut-off value. The study suggests that self-reported smoking status is a valid measure of active smoking, whereas in the case of passive smoking, a combination of questionnaire data and biomarker verification may be required.

Suggested Citation

  • Kinga Polanska & Anna Krol & Pawel Kaluzny & Danuta Ligocka & Karolina Mikolajewska & Seif Shaheen & Robert Walton & Wojciech Hanke, 2016. "Estimation of Saliva Cotinine Cut-Off Points for Active and Passive Smoking during Pregnancy—Polish Mother and Child Cohort (REPRO_PL)," IJERPH, MDPI, vol. 13(12), pages 1-15, December.
    • Handle: RePEc:gam:jijerp:v:13:y:2016:i:12:p:1216-:d:84747
    as

    Download full text from publisher

    File URL: https://www.mdpi.com/1660-4601/13/12/1216/pdf
    Download Restriction: no
    File URL: https://www.mdpi.com/1660-4601/13/12/1216/
    Download Restriction: no
    ---><---

    References listed on IDEAS

    as
    1. Jarvis, M.J. & Tunstall-Pedoe, H. & Feyerabend, C. & Vesey, C. & Saloojee, Y., 1987. "Comparison of tests used to distinguish smokers from nonsmokers," American Journal of Public Health, American Public Health Association, vol. 77(11), pages 1435-1438.
    2. López-Ratón, Mónica & Rodríguez-Álvarez, María Xosé & Cadarso-Suárez, Carmen & Gude-Sampedro, Francisco, 2014. "OptimalCutpoints: An R Package for Selecting Optimal Cutpoints in Diagnostic Tests," Journal of Statistical Software, Foundation for Open Access Statistics, vol. 61(i08).
    3. Łukasz Balwicki & M. Zarzeczna-Baran & Ł. Wierucki & T. Jędrzejczyk & M. Strahl & M. Wrotkowska & M. Goniewicz & T. Zdrojewski, 2016. "Smoking among pregnant women in small towns in Poland," International Journal of Public Health, Springer;Swiss School of Public Health (SSPH+), vol. 61(1), pages 111-118, January.
    Full references (including those not matched with items on IDEAS)

    Citations

    Citations are extracted by the CitEc Project, subscribe to its RSS feed for this item.
    as


    Cited by:

    1. Jolanta Gromadzinska & Kinga Polanska & Lucyna Kozlowska & Karolina Mikolajewska & Iwona Stelmach & Joanna Jerzynska & Wlodzimierz Stelmach & Mariusz Grzesiak & Wojciech Hanke & Wojciech Wasowicz, 2018. "Vitamins A and E during Pregnancy and Allergy Symptoms in an Early Childhood—Lack of Association with Tobacco Smoke Exposure," IJERPH, MDPI, vol. 15(6), pages 1-13, June.
    2. Magdalena Janc & Agnieszka Jankowska & Monika Weteska & Agnieszka Brzozowska & Wojciech Hanke & Joanna Jurewicz & Mercè Garí & Kinga Polańska & Joanna Jerzyńska, 2022. "REPRO_PL-Polish Mother and Child Cohort—Exposure, Health Status, and Neurobehavioral Assessments in Adolescents—Design and Cohort Update," IJERPH, MDPI, vol. 19(21), pages 1-16, October.
    3. Magdalena Chełchowska & Tomasz M. Maciejewski & Joanna Mazur & Joanna Gajewska & Anastasiya Zasimovich & Mariusz Ołtarzewski & Jadwiga Ambroszkiewicz, 2019. "Active Tobacco Smoke Exposure in Utero and Concentrations of Hepcidin and Selected Iron Parameters in Newborns," IJERPH, MDPI, vol. 16(11), pages 1-10, June.
    4. Magdalena Chełchowska & Joanna Gajewska & Tomasz M. Maciejewski & Joanna Mazur & Mariusz Ołtarzewski & Jadwiga Ambroszkiewicz, 2020. "Associations between Maternal and Fetal Levels of Total Adiponectin, High Molecular Weight Adiponectin, Selected Somatomedins, and Birth Weight of Infants of Smoking and Non-Smoking Mothers," IJERPH, MDPI, vol. 17(13), pages 1-14, July.
    5. Ewelina Wesołowska & Agnieszka Jankowska & Elżbieta Trafalska & Paweł Kałużny & Mariusz Grzesiak & Jolanta Dominowska & Wojciech Hanke & Gemma Calamandrei & Kinga Polańska, 2019. "Sociodemographic, Lifestyle, Environmental and Pregnancy-Related Determinants of Dietary Patterns during Pregnancy," IJERPH, MDPI, vol. 16(5), pages 1-15, March.
    6. Kinga Polanska & Anna Krol & Dorota Merecz-Kot & Danuta Ligocka & Karolina Mikolajewska & Fiorino Mirabella & Flavia Chiarotti & Gemma Calamandrei & Wojciech Hanke, 2017. "Environmental Tobacco Smoke Exposure during Pregnancy and Child Neurodevelopment," IJERPH, MDPI, vol. 14(7), pages 1-12, July.

    Most related items

    These are the items that most often cite the same works as this one and are cited by the same works as this one.
    1. Ke-Ting Pan & Giovanni S. Leonardi & Marcella Ucci & Ben Croxford, 2021. "Can Exhaled Carbon Monoxide Be Used as a Marker of Exposure? A Cross-Sectional Study in Young Adults," IJERPH, MDPI, vol. 18(22), pages 1-13, November.
    2. Carla Cruvinel Pontes & Usuf Chikte & Faheema Kimmie-Dhansay & Rajiv T. Erasmus & Andre P. Kengne & Tandi E. Matsha, 2020. "Prevalence of Oral Mucosal Lesions and Relation to Serum Cotinine Levels—Findings from a Cross-Sectional Study in South Africa," IJERPH, MDPI, vol. 17(3), pages 1-10, February.
    3. Magdalena Chełchowska & Tomasz M. Maciejewski & Joanna Mazur & Joanna Gajewska & Anastasiya Zasimovich & Mariusz Ołtarzewski & Jadwiga Ambroszkiewicz, 2019. "Active Tobacco Smoke Exposure in Utero and Concentrations of Hepcidin and Selected Iron Parameters in Newborns," IJERPH, MDPI, vol. 16(11), pages 1-10, June.
    4. Maria Paz Garcia-Portilla & Leticia Garcia-Alvarez & Pilar Alejandra Saiz & Eva Diaz-Mesa & Gonzalo Galvan & Fernando Sarramea & Josefa Garcia-Blanco & Edorta Elizagarate & Julio Bobes, 2013. "Effectiveness of a Multi-Component Smoking Cessation Support Programme (McSCSP) for Patients with Severe Mental Disorders: Study Design," IJERPH, MDPI, vol. 11(1), pages 1-17, December.
    5. Sungroul Kim, 2016. "Overview of Cotinine Cutoff Values for Smoking Status Classification," IJERPH, MDPI, vol. 13(12), pages 1-15, December.
    6. Clément de Chaisemartin & Pierre‐Yves Geoffard & Anne‐Laurence le Faou, 2011. "Workplace smoking ban effects on unhappy smokers," Health Economics, John Wiley & Sons, Ltd., vol. 20(9), pages 1043-1055, September.
    7. Hyun-Seung Lee & Ji-Hyun Cho & Young-Jin Lee & Do-Sim Park, 2022. "Effect of Second-Hand Smoke Exposure on Establishing Urinary Cotinine-Based Optimal Cut-Off Values for Smoking Status Classification in Korean Adults," IJERPH, MDPI, vol. 19(13), pages 1-14, June.
    8. Warisa Thangjai & Suparat Niwitpong & Sa-Aat Niwitpong, 2017. "Confidence Intervals for Mean and Difference between Means of Normal Distributions with Unknown Coefficients of Variation," Mathematics, MDPI, vol. 5(3), pages 1-23, July.
    9. Magdalena Chełchowska & Joanna Gajewska & Tomasz M. Maciejewski & Joanna Mazur & Mariusz Ołtarzewski & Jadwiga Ambroszkiewicz, 2020. "Associations between Maternal and Fetal Levels of Total Adiponectin, High Molecular Weight Adiponectin, Selected Somatomedins, and Birth Weight of Infants of Smoking and Non-Smoking Mothers," IJERPH, MDPI, vol. 17(13), pages 1-14, July.
    10. Mandeep S. Jassal & Cassia Lewis-Land & Richard E. Thompson & Arlene Butz, 2020. "Linkage of Maternal Caregiver Smoking Behaviors on Environmental and Clinical Outcomes of Children with Asthma: A Post-Hoc Analysis of a Financial Incentive Trial Targeting Reduction in Pediatric Toba," IJERPH, MDPI, vol. 17(22), pages 1-14, November.
    11. Yonatan Carl & Andy Vega & Gina Cardona-Acevedo & Marina Stukova & Melissa Matos-Rivera & Anamaris Torres-Sanchez & Melissa Milián-Rodríguez & Brian Torres-Mercado & Grisel Burgos & Raymond L. Trembla, 2022. "Post-Hurricane Distress Scale (PHDS): Determination of General and Disorder-Specific Cutoff Scores," IJERPH, MDPI, vol. 19(9), pages 1-12, April.
    12. Slobodan Milanović & Zoran Trailović & Sladjan D. Milanović & Eduard Hochbichler & Thomas Kirisits & Markus Immitzer & Petr Čermák & Radek Pokorný & Libor Jankovský & Abolfazl Jaafari, 2023. "Country-Level Modeling of Forest Fires in Austria and the Czech Republic: Insights from Open-Source Data," Sustainability, MDPI, vol. 15(6), pages 1-20, March.
    13. Oke Gerke & Antonia Zapf, 2022. "Convergence Behavior of Optimal Cut-Off Points Derived from Receiver Operating Characteristics Curve Analysis: A Simulation Study," Mathematics, MDPI, vol. 10(22), pages 1-14, November.
    14. Tadao Ooka & Yuka Akiyama & Ryoji Shinohara & Hiroshi Yokomichi & Zentaro Yamagata, 2019. "Individual and Regional Characteristics Associated with Maternal Smoking During Pregnancy in Japan: Healthy Parents and Children 21," IJERPH, MDPI, vol. 17(1), pages 1-20, December.
    15. Dean Fantazzini & Yufeng Xiao, 2023. "Detecting Pump-and-Dumps with Crypto-Assets: Dealing with Imbalanced Datasets and Insiders’ Anticipated Purchases," Econometrics, MDPI, vol. 11(3), pages 1-73, August.
    16. Carrieri, V.; Jones, A.M.;, 2017. "Intergenerational transmission of nicotine within families: have e-cigarettes had an impact?," Health, Econometrics and Data Group (HEDG) Working Papers 17/03, HEDG, c/o Department of Economics, University of York.
    17. Florian Fischer, 2016. "Challenges in Creating Evidence in Environmental Health Risk Assessments: The Example of Second-Hand Smoke," Challenges, MDPI, vol. 7(1), pages 1-9, January.
    18. M. Carmen Míguez & Beatriz Pereira & Tiago Miguel Pinto & Bárbara Figueiredo, 2019. "Continued tobacco consumption during pregnancy and women’s depression and anxiety symptoms," International Journal of Public Health, Springer;Swiss School of Public Health (SSPH+), vol. 64(9), pages 1355-1365, December.
    19. Sungroul Kim & Benjamin J. Apelberg & Erika Avila-Tang & Lisa Hepp & Dongmin Yun & Jonathan M. Samet & Patrick N. Breysse, 2014. "Utility and Cutoff Value of Hair Nicotine as a Biomarker of Long-Term Tobacco Smoke Exposure, Compared to Salivary Cotinine," IJERPH, MDPI, vol. 11(8), pages 1-15, August.
    20. Yen‐Chung Ho & Hsin‐Chien Lee & Mei‐Feng Lin & Hsiu‐Ju Chang, 2020. "Correlations among life stress, smoking behavior, and depressive symptoms in adolescents: A descriptive study with a mediating model," Nursing & Health Sciences, John Wiley & Sons, vol. 22(4), pages 949-957, December.

    Corrections

    All material on this site has been provided by the respective publishers and authors. You can help correct errors and omissions. When requesting a correction, please mention this item's handle: RePEc:gam:jijerp:v:13:y:2016:i:12:p:1216-:d:84747. See general information about how to correct material in RePEc.

    If you have authored this item and are not yet registered with RePEc, we encourage you to do it here. This allows to link your profile to this item. It also allows you to accept potential citations to this item that we are uncertain about.

    If CitEc recognized a bibliographic reference but did not link an item in RePEc to it, you can help with this form .

    If you know of missing items citing this one, you can help us creating those links by adding the relevant references in the same way as above, for each refering item. If you are a registered author of this item, you may also want to check the "citations" tab in your RePEc Author Service profile, as there may be some citations waiting for confirmation.

    For technical questions regarding this item, or to correct its authors, title, abstract, bibliographic or download information, contact: MDPI Indexing Manager (email available below). General contact details of provider: https://www.mdpi.com .

    Please note that corrections may take a couple of weeks to filter through the various RePEc services.

    IDEAS is a RePEc service. RePEc uses bibliographic data supplied by the respective publishers.