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REPRO_PL-Polish Mother and Child Cohort—Exposure, Health Status, and Neurobehavioral Assessments in Adolescents—Design and Cohort Update

Author

Listed:
  • Magdalena Janc

    (Department of Environmental and Occupational Health Hazards, Nofer Institute of Occupational Medicine (NIOM), 91-348 Lodz, Poland
    These authors contributed equally to this work.)

  • Agnieszka Jankowska

    (Department of Environmental and Occupational Health Hazards, Nofer Institute of Occupational Medicine (NIOM), 91-348 Lodz, Poland
    These authors contributed equally to this work.)

  • Monika Weteska

    (Department of Pediatrics and Allergy, Copernicus Memorial Hospital, Medical University of Lodz (MUL), 90-329 Lodz, Poland)

  • Agnieszka Brzozowska

    (Department of Pediatrics and Allergy, Copernicus Memorial Hospital, Medical University of Lodz (MUL), 90-329 Lodz, Poland)

  • Wojciech Hanke

    (Department of Environmental Epidemiology, Nofer Institute of Occupational Medicine (NIOM), 91-348 Lodz, Poland)

  • Joanna Jurewicz

    (Department of Toxicology, Medical University of Lodz (MUL), 90-151 Lodz, Poland)

  • Mercè Garí

    (Department of Environmental Chemistry, Institute of Environmental Assessment and Water Research (IDAEA-CSIC), 08034 Barcelona, Spain)

  • Kinga Polańska

    (Department of Environmental and Occupational Health Hazards, Nofer Institute of Occupational Medicine (NIOM), 91-348 Lodz, Poland)

  • Joanna Jerzyńska

    (Department of Pediatrics and Allergy, Copernicus Memorial Hospital, Medical University of Lodz (MUL), 90-329 Lodz, Poland)

Abstract

Early life is a crucial window of opportunity to improve health across the life course. The prospective cohort study design is the most adequate to evaluate the longitudinal effects of exposure, the notification of changes in the exposure level and evaluation of the simultaneous impact of various exposures, as well as the assessment of several health effects and trajectories throughout childhood and adolescence. This paper provides an overview of the Polish Mother and Child cohort (REPRO_PL), with particular emphasis on Phase IV of this study. REPRO_PL is conducted in central Europe, where such longitudinal studies are less frequently implemented. In this population-based prospective cohort, which was established in 2007, three phases covering pregnancy (I), early childhood (II), and early school age (III) periods have already been completed. Phase IV gives a uniform opportunity to follow-up children during adolescence in order to evaluate if the consequences of prenatal and early postnatal exposures still persist at the age of 14. Moreover, we will be able to investigate the associations between simultaneous exposures to a broad spectrum of environmental factors, adolescents’ health and neurobehavioral outcomes, and their trajectories within life, which is a novel framework of high scientific, public health and clinical priority.

Suggested Citation

  • Magdalena Janc & Agnieszka Jankowska & Monika Weteska & Agnieszka Brzozowska & Wojciech Hanke & Joanna Jurewicz & Mercè Garí & Kinga Polańska & Joanna Jerzyńska, 2022. "REPRO_PL-Polish Mother and Child Cohort—Exposure, Health Status, and Neurobehavioral Assessments in Adolescents—Design and Cohort Update," IJERPH, MDPI, vol. 19(21), pages 1-16, October.
    • Handle: RePEc:gam:jijerp:v:19:y:2022:i:21:p:14167-:d:957591
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    References listed on IDEAS

    as
    1. Ewelina Wesołowska & Agnieszka Jankowska & Elżbieta Trafalska & Paweł Kałużny & Mariusz Grzesiak & Jolanta Dominowska & Wojciech Hanke & Gemma Calamandrei & Kinga Polańska, 2019. "Sociodemographic, Lifestyle, Environmental and Pregnancy-Related Determinants of Dietary Patterns during Pregnancy," IJERPH, MDPI, vol. 16(5), pages 1-15, March.
    2. Kinga Polanska & Anna Krol & Pawel Kaluzny & Danuta Ligocka & Karolina Mikolajewska & Seif Shaheen & Robert Walton & Wojciech Hanke, 2016. "Estimation of Saliva Cotinine Cut-Off Points for Active and Passive Smoking during Pregnancy—Polish Mother and Child Cohort (REPRO_PL)," IJERPH, MDPI, vol. 13(12), pages 1-15, December.
    3. Kinga Polanska & Wojciech Hanke & Natalia Pawlas & Ewelina Wesolowska & Agnieszka Jankowska & Marta Jagodic & Darja Mazej & Jolanta Dominowska & Mariusz Grzesiak & Fiorino Mirabella & Flavia Chiarotti, 2018. "Sex-Dependent Impact of Low-Level Lead Exposure during Prenatal Period on Child Psychomotor Functions," IJERPH, MDPI, vol. 15(10), pages 1-11, October.
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