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Chromosome structure and gene regulation

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  • Widom, Jonathan

Abstract

The packaging of DNA in chromosomes presents obstacles to the action of gene regulatory proteins and polymerases on their natural chromatin substrates. We critically assess previously existing ideas for how these obstacles may be overcome, and then summarize a recently proposed model and discuss its implications.

Suggested Citation

  • Widom, Jonathan, 1997. "Chromosome structure and gene regulation," Physica A: Statistical Mechanics and its Applications, Elsevier, vol. 244(1), pages 497-509.
    • Handle: RePEc:eee:phsmap:v:244:y:1997:i:1:p:497-509
    DOI: 10.1016/S0378-4371(97)00225-2
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    References listed on IDEAS

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    1. Wolffers, Ivan, 1995. "The role of pharmaceuticals in the privatization process in Vietnam's health-care system," Social Science & Medicine, Elsevier, vol. 41(9), pages 1325-1332, November.
    2. Klug, Thomas A., 1984. "No Strength Without Union: An Illustrated History of Ohio Workers, 1803–1980. By Raymond Boryczka and Lorin Lee Cary. (Ohio Historical Society, 1982. ix + 328 pp. $19.95.)," Business History Review, Cambridge University Press, vol. 58(1), pages 142-143, April.
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    Cited by:

    1. Ben-Haı̈m, Eli & Lesne, Annick & Victor, Jean-Marc, 2002. "Adaptive elastic properties of chromatin fiber," Physica A: Statistical Mechanics and its Applications, Elsevier, vol. 314(1), pages 592-599.

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