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Biomedical innovation at the laboratory, clinical and commercial interface: A new method for mapping research projects, publications and patents in the field of microarrays

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  • Mogoutov, Andrei
  • Cambrosio, Alberto
  • Keating, Peter
  • Mustar, Philippe

Abstract

Using the example of microarrays, one of the constitutive technologies of post-genomic biomedicine, this paper introduces a method for analyzing publications, patents and research grants as proxies for “triple-helix interfaces” between university, industry and government activities. Our method creates bridges that allow one to move seamlessly between publication, patent and research project databases that use different fields and formats, and contain different information. These links do not require pre-defined categories in order to search for correspondences between sub-topics or research areas in the three databases. Finally, our results are not restricted to quantitative information but, rather, allow one to carry out qualitative investigations of the content of research activities. Our approach draws on a combination of text-mining and network analysis/mapping software packages.

Suggested Citation

  • Mogoutov, Andrei & Cambrosio, Alberto & Keating, Peter & Mustar, Philippe, 2008. "Biomedical innovation at the laboratory, clinical and commercial interface: A new method for mapping research projects, publications and patents in the field of microarrays," Journal of Informetrics, Elsevier, vol. 2(4), pages 341-353.
    • Handle: RePEc:eee:infome:v:2:y:2008:i:4:p:341-353
    DOI: 10.1016/j.joi.2008.06.005
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    References listed on IDEAS

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    1. Eric von Hippel, 1986. "Lead Users: A Source of Novel Product Concepts," Management Science, INFORMS, vol. 32(7), pages 791-805, July.
    2. Philippe Mustar, 1997. "How French academics create hi-tech companies: The conditions for success or failure," Science and Public Policy, Oxford University Press, vol. 24(1), pages 37-43, February.
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    5. Arnold Verbeek & Koenraad Debackere & Marc Luwel & Petra Andries & Edwin Zimmermann & Filip Deleus, 2002. "Linking science to technology: Using bibliographic references in patents to build linkage schemes," Scientometrics, Springer;Akadémiai Kiadó, vol. 54(3), pages 399-420, July.
    6. Arnold Verbeek & Koenraad Debackere & Marc Luwel, 2003. "Science cited in patents: A geographic "flow" analysis of bibliographic citation patterns in patents," Scientometrics, Springer;Akadémiai Kiadó, vol. 58(2), pages 241-263, October.
    7. Mogoutov, Andrei & Kahane, Bernard, 2007. "Data search strategy for science and technology emergence: A scalable and evolutionary query for nanotechnology tracking," Research Policy, Elsevier, vol. 36(6), pages 893-903, July.
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    Cited by:

    1. Gurney, Thomas & Horlings, Edwin & van den Besselaar, Peter & Sumikura, Koichi & Schoen, Antoine & Laurens, Patricia & Pardo, Daniel, 2014. "Analysing knowledge capture mechanisms: Methods and a stylised bioventure case," Journal of Informetrics, Elsevier, vol. 8(1), pages 259-272.
    2. Shin, Hyunjin & Woo, Hyun Goo & Sohn, Kyung-Ah & Lee, Sungjoo, 2023. "Comparing research trends with patenting activities in the biomedical sector: The case of dementia," Technological Forecasting and Social Change, Elsevier, vol. 195(C).
    3. Edgar Schiebel & Marianne Hörlesberger & Ivana Roche & Claire François & Dominique Besagni, 2010. "An advanced diffusion model to identify emergent research issues: the case of optoelectronic devices," Scientometrics, Springer;Akadémiai Kiadó, vol. 83(3), pages 765-781, June.
    4. Tomaz Bartol & Karmen Stopar, 2015. "Nano language and distribution of article title terms according to power laws," Scientometrics, Springer;Akadémiai Kiadó, vol. 103(2), pages 435-451, May.
    5. Patrick Wolf & Tobias Buchmann, 2021. "Analyzing development patterns in research networks and technology," Review of Evolutionary Political Economy, Springer, vol. 2(1), pages 55-81, April.
    6. Jordan A. Comins & Loet Leydesdorff, 2017. "Citation algorithms for identifying research milestones driving biomedical innovation," Scientometrics, Springer;Akadémiai Kiadó, vol. 110(3), pages 1495-1504, March.
    7. Leydesdorff, Loet & Welbers, Kasper, 2011. "The semantic mapping of words and co-words in contexts," Journal of Informetrics, Elsevier, vol. 5(3), pages 469-475.

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