Unified computational methods for regression analysis of zero-inflated and bound-inflated data
Bounded data with excess observations at the boundary are common in many areas of application. Various individual cases of inflated mixture models have been studied in the literature for bound-inflated data, yet the computational methods have been developed separately for each type of model. In this article we use a common framework for computing these models, and expand the range of models for both discrete and semi-continuous data with point inflation at the lower boundary. The quasi-Newton and EM algorithms are adapted and compared for estimation of model parameters. The numerical Hessian and generalized Louis method are investigated as means for computing standard errors after optimization. Correlated data are included in this framework via generalized estimating equations. The estimation of parameters and effectiveness of standard errors are demonstrated through simulation and in the analysis of data from an ultrasound bioeffect study. The unified approach enables reliable computation for a wide class of inflated mixture models and comparison of competing models.
If you experience problems downloading a file, check if you have the proper application to view it first. In case of further problems read the IDEAS help page. Note that these files are not on the IDEAS site. Please be patient as the files may be large.
As the access to this document is restricted, you may want to look for a different version under "Related research" (further below) or search for a different version of it.
References listed on IDEAS
Please report citation or reference errors to , or , if you are the registered author of the cited work, log in to your RePEc Author Service profile, click on "citations" and make appropriate adjustments.:
- Zhou Xiao-Hua & Wanzhu Tu, 1999. "Comparison of Several Independent Population Means When Their Samples Contain Log-Normal and Possibly Zero Observations," Biometrics, The International Biometric Society, vol. 55(2), pages 645-651, 06.
- Hansen, Lars Peter, 1982. "Large Sample Properties of Generalized Method of Moments Estimators," Econometrica, Econometric Society, vol. 50(4), pages 1029-54, July.
- Zhang, Min & Strawderman, Robert L. & Cowen, Mark E. & Wells, Martin T., 2006. "Bayesian Inference for a Two-Part Hierarchical Model: An Application to Profiling Providers in Managed Health Care," Journal of the American Statistical Association, American Statistical Association, vol. 101, pages 934-945, September.
- Cragg, John G, 1971. "Some Statistical Models for Limited Dependent Variables with Application to the Demand for Durable Goods," Econometrica, Econometric Society, vol. 39(5), pages 829-44, September.
- Paul S. Albert & Joannie Shen, 2005. "Modelling longitudinal semicontinuous emesis volume data with serial correlation in an acupuncture clinical trial," Journal of the Royal Statistical Society Series C, Royal Statistical Society, vol. 54(4), pages 707-720.
- Ghosh, Pulak & Albert, Paul S., 2009. "A Bayesian analysis for longitudinal semicontinuous data with an application to an acupuncture clinical trial," Computational Statistics & Data Analysis, Elsevier, vol. 53(3), pages 699-706, January.
When requesting a correction, please mention this item's handle: RePEc:eee:csdana:v:54:y:2010:i:6:p:1525-1534. See general information about how to correct material in RePEc.
For technical questions regarding this item, or to correct its authors, title, abstract, bibliographic or download information, contact: (Shamier, Wendy)
If you have authored this item and are not yet registered with RePEc, we encourage you to do it here. This allows to link your profile to this item. It also allows you to accept potential citations to this item that we are uncertain about.
If references are entirely missing, you can add them using this form.
If the full references list an item that is present in RePEc, but the system did not link to it, you can help with this form.
If you know of missing items citing this one, you can help us creating those links by adding the relevant references in the same way as above, for each refering item. If you are a registered author of this item, you may also want to check the "citations" tab in your profile, as there may be some citations waiting for confirmation.
Please note that corrections may take a couple of weeks to filter through the various RePEc services.