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Still‐births among the offspring of male radiation workers at the Sellafield nuclear reprocessing plant: detailed results and statistical aspects

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  • Mark S. Pearce
  • Heather O. Dickinson
  • Murray Aitkin
  • Louise Parker

Abstract

Summary. This study investigates whether there was evidence of increasing risk of still‐birth with increasing paternal exposure to ionizing radiation received during employment at the Sellafield nuclear installation before the child was conceived. A significant positive association is found between the total paternal preconceptional exposure to external ionizing radiation and the risk of still‐birth (after adjustment for year of birth, social class, birth order and paternal age, odds ratio at 100 mSv 1.24 (95% confidence interval 1.04–1.45)). A summary of the principal scientific findings of this study has been published in the Lancet. This paper describes in detail the statistical methods that were used in the investigation and presents the results in full.

Suggested Citation

  • Mark S. Pearce & Heather O. Dickinson & Murray Aitkin & Louise Parker, 2002. "Still‐births among the offspring of male radiation workers at the Sellafield nuclear reprocessing plant: detailed results and statistical aspects," Journal of the Royal Statistical Society Series A, Royal Statistical Society, vol. 165(3), pages 523-548, October.
    • Handle: RePEc:bla:jorssa:v:165:y:2002:i:3:p:523-548
    DOI: 10.1111/1467-985X.t01-1-00251
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    References listed on IDEAS

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    1. Yuri E. Dubrova & Mark Plumb & Bruno Gutierrez & Emma Boulton & Alec J. Jeffreys, 2000. "Transgenerational mutation by radiation," Nature, Nature, vol. 405(6782), pages 37-37, May.
    2. Murray Aitkin, 1999. "A General Maximum Likelihood Analysis of Variance Components in Generalized Linear Models," Biometrics, The International Biometric Society, vol. 55(1), pages 117-128, March.
    3. Anthony R. Brady, 1998. "Adjusted population attributable fractions from logistic regression," Stata Technical Bulletin, StataCorp LLC, vol. 7(42).
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