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M1 Extra Weight in the Balance: The Role of Macrophages in Obesity

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  • Cristhiane Favero de Aguiar

    (Department of Genetics, Evolution, Microbiology and Immunology, Institute of Biology, University of Campinas (UNICAMP), Brazil)

  • Pedro M Mendes Moraes Vieira

    (Department of Genetics, Evolution, Microbiology and Immunology, Institute of Biology, University of Campinas (UNICAMP), Brazil)

Abstract

Obesity affects millions of people worldwide and is a complex and multifactorial syndrome. Alterations in eating habits and lifestyle in developed countries increased obesity rates drastically through the past years and also the deaths associated with this condition. The immune system is an important component to maintain adipose tissue homeostasis and also to promote inflammation during obesity. In this mini review, we will briefly describe the main factors that contribute to systemic low-grade inflammation in obesity and lead to insulin resistance.

Suggested Citation

  • Cristhiane Favero de Aguiar & Pedro M Mendes Moraes Vieira, 2018. "M1 Extra Weight in the Balance: The Role of Macrophages in Obesity," Current Research in Diabetes & Obesity Journal, Juniper Publishers Inc., vol. 7(4), pages 72-75, June.
    • Handle: RePEc:adp:jcrdoj:v:7:y:2018:i:4:p:72-75
    DOI: 10.19080/CRDOJ.2018.07.555717
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    References listed on IDEAS

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    1. Luc F. Van Gaal & Ilse L. Mertens & Christophe E. De Block, 2006. "Mechanisms linking obesity with cardiovascular disease," Nature, Nature, vol. 444(7121), pages 875-880, December.
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    Keywords

    juniper publishers; diabetes journals; diabetes impact factor; endocrinology journal; endocrinology impact factor; endocrinology research journal; endocrinology research articles; diabetes open access journals; Obesity Journal; Diabetes & Obesity Journal;
    All these keywords.

    JEL classification:

    • R00 - Urban, Rural, Regional, Real Estate, and Transportation Economics - - General - - - General
    • Z0 - Other Special Topics - - General

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