Content
September 2016, Volume 537, Issue 7621
- 13-13 Kamakura replies
by M. Kamakura - 145-145 Lysosomal storage disorders
by Michelle Grayson - 146-147 Myriad maladies
by Michael Eisenstein - 148-150 Biomedicine: A rare opportunity
by Kelly Rae Chi - 151-151 Perspective: The rare must become common
by Marc C. Patterson - 152-154 Advocacy: Strong foundations
by James Mitchell Crow - 154-157 Drug development: Through the barrier
by Sarah DeWeerdt - 158-159 Gene therapy: A new chapter
by Anthony King - 160-161 Perspective: Finding common ground
by Anthony H. Futerman & John Hardy - 162-164 Screening: Baby's first test
by Sujata Gupta - 165-165 Lysosomal storage disorders: 4 big questions
by Michael Eisenstein - 451-451 Religion and science can have a true dialogue
by Kathryn Pritchard - 457-458 Geneticists attempt to heal rifts with Aboriginal communities
by Ewen Callaway - 458-459 US sharpens surveillance of crippling solar storms
by Alexandra Witze - 459-459 Detailed map shows Milky Way is bigger than we thought
by Davide Castelvecchi - 460-461 Titanic clash over CRISPR patents turns ugly
by Heidi Ledford - 462-463 Human skeleton found on famed Antikythera shipwreck
by Jo Marchant - 471-473 Science’s 1%: How income inequality is getting worse in research
by Corie Lok - 475-479 End class wars
by Mike Savage - 479-482 Income inequality is cyclical
by Branko Milanovic - 484-485 Public health: Beating Ebola
by Peter Piot - 485-485 Books in brief
by Barbara Kiser - 488-488 Health research: Africa–India health-science partnerships
by Shahid Jameel & Thomas Kariuki & Simon Kay - 488-488 Species loss: lack of data leaves a gap
by Lucie Bland & Ben Collen - 488-488 Geoengineering: Code of conduct for geoengineering
by Anna-Maria Hubert & Tim Kruger & Steve Rayner - 488-488 Wildlife monitoring: Lure gamers into citizen science
by Rassim Khelifa - 488-488 Pollution: Do microplastics spill on to farm soils?
by Luca Nizzetto & Sindre Langaas & Martyn Futter - 489-489 James Cronin (1931–2016)
by Alan Watson - 492-493 Structure of aggregates revealed
by Robert Tycko - 493-494 Motion controlled by sound
by Adrian Neild - 494-496 Panoramic views of the early epigenome
by Juan M. Vaquerizas & Maria-Elena Torres-Padilla - 496-497 Migration of giants
by Amaury Triaud - 497-499 Channelling potassium to fight cancer
by K. George Chandy & Raymond S. Norton - 499-500 Multitasking materials from atomic templates
by Manfred Fiebig - 500-501 Evidence of life in Earth's oldest rocks
by Abigail C. Allwood - 503-507 Perimortem fractures in Lucy suggest mortality from fall out of tall tree
by John Kappelman & Richard A. Ketcham & Stephen Pearce & Lawrence Todd & Wiley Akins & Matthew W. Colbert & Mulugeta Feseha & Jessica A. Maisano & Adrienne Witzel - 508-514 High-throughput discovery of novel developmental phenotypes
by Mary E. Dickinson & Ann M. Flenniken & Xiao Ji & Lydia Teboul & Michael D. Wong & Jacqueline K. White & Terrence F. Meehan & Wolfgang J. Weninger & Henrik Westerberg & Hibret Adissu & Candice N. Baker & Lynette Bower & James M. Brown & L. Brianna Caddle & Francesco Chiani & Dave Clary & James Cleak & Mark J. Daly & James M. Denegre & Brendan Doe & Mary E. Dolan & Sarah M. Edie & Helmut Fuchs & Valerie Gailus-Durner & Antonella Galli & Alessia Gambadoro & Juan Gallegos & Shiying Guo & Neil R. Horner & Chih-Wei Hsu & Sara J. Johnson & Sowmya Kalaga & Lance C. Keith & Louise Lanoue & Thomas N. Lawson & Monkol Lek & Manuel Mark & Susan Marschall & Jeremy Mason & Melissa L. McElwee & Susan Newbigging & Lauryl M. J. Nutter & Kevin A. Peterson & Ramiro Ramirez-Solis & Douglas J. Rowland & Edward Ryder & Kaitlin E. Samocha & John R. Seavitt & Mohammed Selloum & Zsombor Szoke-Kovacs & Masaru Tamura & Amanda G. Trainor & Ilinca Tudose & Shigeharu Wakana & Jonathan Warren & Olivia Wendling & David B. West & Leeyean Wong & Atsushi Yoshiki & Wolfgang Wurst & Daniel G. MacArthur & Glauco P. Tocchini-Valentini & Xiang Gao & Paul Flicek & Allan Bradley & William C. Skarnes & Monica J. Justice & Helen E. Parkinson & Mark Moore & Sara Wells & Robert E. Braun & Karen L. Svenson & Martin Hrabe de Angelis & Yann Herault & Tim Mohun & Ann-Marie Mallon & R. Mark Henkelman & Steve D. M. Brown & David J. Adams & K. C. Kent Lloyd & Colin McKerlie & Arthur L. Beaudet & Maja Bućan & Stephen A. Murray - 515-517 A partially differentiated interior for (1) Ceres deduced from its gravity field and shape
by R. S. Park & A. S. Konopliv & B. G. Bills & N. Rambaux & J. C. Castillo-Rogez & C. A. Raymond & A. T. Vaughan & A. I. Ermakov & M. T. Zuber & R. R. Fu & M. J. Toplis & C. T. Russell & A. Nathues & F. Preusker - 518-522 Holograms for acoustics
by Kai Melde & Andrew G. Mark & Tian Qiu & Peer Fischer - 523-527 Atomically engineered ferroic layers yield a room-temperature magnetoelectric multiferroic
by Julia A. Mundy & Charles M. Brooks & Megan E. Holtz & Jarrett A. Moyer & Hena Das & Alejandro F. Rébola & John T. Heron & James D. Clarkson & Steven M. Disseler & Zhiqi Liu & Alan Farhan & Rainer Held & Robert Hovden & Elliot Padgett & Qingyun Mao & Hanjong Paik & Rajiv Misra & Lena F. Kourkoutis & Elke Arenholz & Andreas Scholl & Julie A. Borchers & William D. Ratcliff & Ramamoorthy Ramesh & Craig J. Fennie & Peter Schiffer & David A. Muller & Darrell G. Schlom - 528-531 Switching on electrocatalytic activity in solid oxide cells
by Jae-ha Myung & Dragos Neagu & David N. Miller & John T. S. Irvine - 532-534 Molecular-scale evidence of aerosol particle formation via sequential addition of HIO3
by Mikko Sipilä & Nina Sarnela & Tuija Jokinen & Henning Henschel & Heikki Junninen & Jenni Kontkanen & Stefanie Richters & Juha Kangasluoma & Alessandro Franchin & Otso Peräkylä & Matti P. Rissanen & Mikael Ehn & Hanna Vehkamäki & Theo Kurten & Torsten Berndt & Tuukka Petäjä & Douglas Worsnop & Darius Ceburnis & Veli-Matti Kerminen & Markku Kulmala & Colin O’Dowd - 535-538 Rapid emergence of life shown by discovery of 3,700-million-year-old microbial structures
by Allen P. Nutman & Vickie C. Bennett & Clark R. L. Friend & Martin J. Van Kranendonk & Allan R. Chivas - 539-543 Ionic immune suppression within the tumour microenvironment limits T cell effector function
by Robert Eil & Suman K. Vodnala & David Clever & Christopher A. Klebanoff & Madhusudhanan Sukumar & Jenny H. Pan & Douglas C. Palmer & Alena Gros & Tori N. Yamamoto & Shashank J. Patel & Geoffrey C. Guittard & Zhiya Yu & Valentina Carbonaro & Klaus Okkenhaug & David S. Schrump & W. Marston Linehan & Rahul Roychoudhuri & Nicholas P. Restifo - 544-547 Fumarate is an epigenetic modifier that elicits epithelial-to-mesenchymal transition
by Marco Sciacovelli & Emanuel Gonçalves & Timothy Isaac Johnson & Vincent Roberto Zecchini & Ana Sofia Henriques da Costa & Edoardo Gaude & Alizee Vercauteren Drubbel & Sebastian Julian Theobald & Sandra Riekje Abbo & Maxine Gia Binh Tran & Vinothini Rajeeve & Simone Cardaci & Sarah Foster & Haiyang Yun & Pedro Cutillas & Anne Warren & Vincent Gnanapragasam & Eyal Gottlieb & Kristian Franze & Brian Huntly & Eamonn Richard Maher & Patrick Henry Maxwell & Julio Saez-Rodriguez & Christian Frezza - 548-552 Broad histone H3K4me3 domains in mouse oocytes modulate maternal-to-zygotic transition
by John Arne Dahl & Inkyung Jung & Håvard Aanes & Gareth D. Greggains & Adeel Manaf & Mads Lerdrup & Guoqiang Li & Samantha Kuan & Bin Li & Ah Young Lee & Sebastian Preissl & Ingunn Jermstad & Mads Haugland Haugen & Rajikala Suganthan & Magnar Bjørås & Klaus Hansen & Knut Tomas Dalen & Peter Fedorcsak & Bing Ren & Arne Klungland - 553-557 Allelic reprogramming of the histone modification H3K4me3 in early mammalian development
by Bingjie Zhang & Hui Zheng & Bo Huang & Wenzhi Li & Yunlong Xiang & Xu Peng & Jia Ming & Xiaotong Wu & Yu Zhang & Qianhua Xu & Wenqiang Liu & Xiaochen Kou & Yanhong Zhao & Wenteng He & Chong Li & Bo Chen & Yuanyuan Li & Qiujun Wang & Jing Ma & Qiangzong Yin & Kehkooi Kee & Anming Meng & Shaorong Gao & Feng Xu & Jie Na & Wei Xie - 558-562 Distinct features of H3K4me3 and H3K27me3 chromatin domains in pre-implantation embryos
by Xiaoyu Liu & Chenfei Wang & Wenqiang Liu & Jingyi Li & Chong Li & Xiaochen Kou & Jiayu Chen & Yanhong Zhao & Haibo Gao & Hong Wang & Yong Zhang & Yawei Gao & Shaorong Gao - 563-566 A blue-light photoreceptor mediates the feedback regulation of photosynthesis
by Dimitris Petroutsos & Ryutaro Tokutsu & Shinichiro Maruyama & Serena Flori & Andre Greiner & Leonardo Magneschi & Loic Cusant & Tilman Kottke & Maria Mittag & Peter Hegemann & Giovanni Finazzi & Jun Minagawa - 567-571 Structural basis of kainate subtype glutamate receptor desensitization
by Joel R. Meyerson & Sagar Chittori & Alan Merk & Prashant Rao & Tae Hee Han & Mihaela Serpe & Mark L. Mayer & Sriram Subramaniam - 572-572 Correction: Corrigendum: A large light-mass component of cosmic rays at 1017–1017.5 electronvolts from radio observations
by S. Buitink & A. Corstanje & H. Falcke & J. R. Hörandel & T. Huege & A. Nelles & J. P. Rachen & L. Rossetto & P. Schellart & O. Scholten & S. ter Veen & S. Thoudam & T. N. G. Trinh & J. Anderson & A. Asgekar & I. M. Avruch & M. E. Bell & M. J. Bentum & G. Bernardi & P. Best & A. Bonafede & F. Breitling & J. W. Broderick & W. N. Brouw & M. Brüggen & H. R. Butcher & D. Carbone & B. Ciardi & J. E. Conway & F. de Gasperin & E. de Geus & A. Deller & R.-J. Dettmar & G. van Diepen & S. Duscha & J. Eislöffel & D. Engels & J. E. Enriquez & R. A. Fallows & R. Fender & C. Ferrari & W. Frieswijk & M. A. Garrett & J. M. Grießmeier & A. W. Gunst & M. P. van Haarlem & T. E. Hassall & G. Heald & J. W. T. Hessels & M. Hoeft & A. Horneffer & M. Iacobelli & H. Intema & E. Juette & A. Karastergiou & V. I. Kondratiev & M. Kramer & M. Kuniyoshi & G. Kuper & J. van Leeuwen & G. M. Loose & P. Maat & G. Mann & S. Markoff & R. McFadden & D. McKay-Bukowski & J. P. McKean & M. Mevius & D. D. Mulcahy & H. Munk & M. J. Norden & E. Orru & H. Paas & M. Pandey-Pommier & V. N. Pandey & M. Pietka & R. Pizzo & A. G. Polatidis & W. Reich & H. J. A. Röttgering & A. M. M. Scaife & D. J. Schwarz & M. Serylak & J. Sluman & O. Smirnov & B. W. Stappers & M. Steinmetz & A. Stewart & J. Swinbank & M. Tagger & Y. Tang & C. Tasse & M. C. Toribio & R. Vermeulen & C. Vocks & C. Vogt & R. J. van Weeren & R. A. M. J. Wijers & S. J. Wijnholds & M. W. Wise & O. Wucknitz & S. Yatawatta & P. Zarka & J. A. Zensus - 573-576 Salaries: Reality check
by Chris Woolston - 578-578 Houston, Houston, Do You Read James Tiptree?
by Rachael K. Jones
September 2016, Volume 537, Issue 7620
- 7-9 Amyloid-β transmission or unexamined bias?
by Hieab H. H. Adams & Sonja A. Swanson & Albert Hofman & M. Arfan Ikram - 9-9 Collinge et al. reply
by John Collinge & Zane Jaunmuktane & Simon Mead & Peter Rudge & Sebastian Brandner - 97-97 Kidney cancer
by Brian Owens - 98-99 The silent disease
by Graham Shaw - 100-102 Obesity: The fat advantage
by Sujata Gupta - 103-104 Alcohol: Fortifying spirits
by Jesse Emspak - 105-105 Perspective: Beyond the genome
by John Leppert & Chirag Patel - 106-108 Targeted therapy: An elusive cancer target
by Carolyn Brown - 109-110 Immunotherapy: Controlled attack
by Charles Schmidt - 111-111 Perspective: What next for treatment?
by Robert J. Motzer - 281-281 Illusory fears must not stifle chimaera research
by Insoo Hyun - 287-288 Mystery deportation of particle physicist leads to swell of protest
by Declan Butler - 288-289 Cancer experts unveil wishlist for US government ‘moonshot’
by Heidi Ledford - 289-290 Medical Nobel prize committee deals with surgical scandal
by Alison Abbott - 290-291 DNA reveals that giraffes are four species — not one
by Chris Woolston - 291-292 Ebola virus lingers longer than scientists thought
by Erika Check Hayden - 292-293 Milky Way mapper: 6 ways the Gaia spacecraft will change astronomy
by Davide Castelvecchi - 294-296 The office experiment: Can science build the perfect workspace?
by Emily Anthes - 298-300 Secrets of life in the soil
by Rachel Cernansky - 301-303 Agricultural R&D is on the move
by Philip G. Pardey & Connie Chan-Kang & Steven P. Dehmer & Jason M. Beddow - 304-305 Technology: Selfies in space
by Alexandra Witze - 305-305 Books in brief
by Barbara Kiser - 306-306 Dendrology: The community of trees
by Richard Fortey - 307-307 Clearing the way for reef destruction
by April E. Reside & Tom C. L. Bridge & Jodie L. Rummer - 307-307 Harness passion of private fossil owners
by Robert R. Reisz & Michael W. Caldwell - 307-307 Avoid bias against junior researchers
by Andrew K. Skidmore - 307-307 Species can be named from photos
by Thomas Pape - 307-307 China's sponge cities to soak up rainwater
by Dasheng Liu - 308-308 Seymour Papert (1928–2016)
by Gary S. Stager - 310-311 Extraordinary world
by James M. D. Day - 311-312 Teenage tetrapods
by Nadia B. Fröbisch - 312-314 Cytotoxic T cells that escape exhaustion
by Cindy S. Ma & Stuart G. Tangye - 314-315 Geography matters for Arabidopsis
by Outi Savolainen & Martin Lascoux - 315-316 Not so creepy under stress
by Jonathan Cormier - 316-317 Dietary protection for genes
by Junko Oshima & George M. Martin - 319-319 The protein world
by Joshua Finkelstein & Alex Eccleston & Sadaf Shadan - 320-327 The coming of age of de novo protein design
by Po-Ssu Huang & Scott E. Boyken & David Baker - 328-338 Proteome complexity and the forces that drive proteome imbalance
by J. Wade Harper & Eric J. Bennett - 339-346 Unravelling biological macromolecules with cryo-electron microscopy
by Rafael Fernandez-Leiro & Sjors H. W. Scheres - 347-355 Mass-spectrometric exploration of proteome structure and function
by Ruedi Aebersold & Matthias Mann - 357-362 Locus coeruleus and dopaminergic consolidation of everyday memory
by Tomonori Takeuchi & Adrian J. Duszkiewicz & Alex Sonneborn & Patrick A. Spooner & Miwako Yamasaki & Masahiko Watanabe & Caroline C. Smith & Guillén Fernández & Karl Deisseroth & Robert W. Greene & Richard G. M. Morris - 363-368 Activation mechanism of endothelin ETB receptor by endothelin-1
by Wataru Shihoya & Tomohiro Nishizawa & Akiko Okuta & Kazutoshi Tani & Naoshi Dohmae & Yoshinori Fujiyoshi & Osamu Nureki & Tomoko Doi - 369-373 m6A RNA methylation promotes XIST-mediated transcriptional repression
by Deepak P. Patil & Chun-Kan Chen & Brian F. Pickering & Amy Chow & Constanza Jackson & Mitchell Guttman & Samie R. Jaffrey - 374-377 A radio-pulsing white dwarf binary star
by T. R. Marsh & B. T. Gänsicke & S. Hümmerich & F.-J. Hambsch & K. Bernhard & C. Lloyd & E. Breedt & E. R. Stanway & D. T. Steeghs & S. G. Parsons & O. Toloza & M. R. Schreiber & P. G. Jonker & J. van Roestel & T. Kupfer & A. F. Pala & V. S. Dhillon & L. K. Hardy & S. P. Littlefair & A. Aungwerojwit & S. Arjyotha & D. Koester & J. J. Bochinski & C. A. Haswell & P. Frank & P. J. Wheatley - 378-381 Extreme creep resistance in a microstructurally stable nanocrystalline alloy
by K. A. Darling & M. Rajagopalan & M. Komarasamy & M. A. Bhatia & B. C. Hornbuckle & R. S. Mishra & K. N. Solanki - 382-386 Enhanced electrocatalytic CO2 reduction via field-induced reagent concentration
by Min Liu & Yuanjie Pang & Bo Zhang & Phil De Luna & Oleksandr Voznyy & Jixian Xu & Xueli Zheng & Cao Thang Dinh & Fengjia Fan & Changhong Cao & F. Pelayo García de Arquer & Tina Saberi Safaei & Adam Mepham & Anna Klinkova & Eugenia Kumacheva & Tobin Filleter & David Sinton & Shana O. Kelley & Edward H. Sargent - 387-393 Catalytic enantioselective 1,6-conjugate additions of propargyl and allyl groups
by Fanke Meng & Xiben Li & Sebastian Torker & Ying Shi & Xiao Shen & Amir H. Hoveyda - 394-398 A nucleosynthetic origin for the Earth’s anomalous 142Nd composition
by C. Burkhardt & L. E. Borg & G. A. Brennecka & Q. R. Shollenberger & N. Dauphas & T. Kleine - 399-402 Primitive Solar System materials and Earth share a common initial 142Nd abundance
by A. Bouvier & M. Boyet - 403-407 Discovery of species-wide tool use in the Hawaiian crow
by Christian Rutz & Barbara C. Klump & Lisa Komarczyk & Rosanna Leighton & Joshua Kramer & Saskia Wischnewski & Shoko Sugasawa & Michael B. Morrissey & Richard James & James J. H. St Clair & Richard A. Switzer & Bryce M. Masuda - 408-411 Life history of the stem tetrapod Acanthostega revealed by synchrotron microtomography
by Sophie Sanchez & Paul Tafforeau & Jennifer A. Clack & Per E. Ahlberg - 412-416 Follicular CXCR5-expressing CD8+ T cells curtail chronic viral infection
by Ran He & Shiyue Hou & Cheng Liu & Anli Zhang & Qiang Bai & Miao Han & Yu Yang & Gang Wei & Ting Shen & Xinxin Yang & Lifan Xu & Xiangyu Chen & Yaxing Hao & Pengcheng Wang & Chuhong Zhu & Juanjuan Ou & Houjie Liang & Ting Ni & Xiaoyan Zhang & Xinyuan Zhou & Kai Deng & Yaokai Chen & Yadong Luo & Jianqing Xu & Hai Qi & Yuzhang Wu & Lilin Ye - 417-421 Defining CD8+ T cells that provide the proliferative burst after PD-1 therapy
by Se Jin Im & Masao Hashimoto & Michael Y. Gerner & Junghwa Lee & Haydn T. Kissick & Matheus C. Burger & Qiang Shan & J. Scott Hale & Judong Lee & Tahseen H. Nasti & Arlene H. Sharpe & Gordon J. Freeman & Ronald N. Germain & Helder I. Nakaya & Hai-Hui Xue & Rafi Ahmed - 422-426 A PGC1α-mediated transcriptional axis suppresses melanoma metastasis
by Chi Luo & Ji-Hong Lim & Yoonjin Lee & Scott R. Granter & Ajith Thomas & Francisca Vazquez & Hans R. Widlund & Pere Puigserver - 427-431 Restricted diet delays accelerated ageing and genomic stress in DNA-repair-deficient mice
by W. P. Vermeij & M. E. T. Dollé & E. Reiling & D. Jaarsma & C. Payan-Gomez & C. R. Bombardieri & H. Wu & A. J. M. Roks & S. M. Botter & B. C. van der Eerden & S. A. Youssef & R. V. Kuiper & B. Nagarajah & C. T. van Oostrom & R. M. C. Brandt & S. Barnhoorn & S. Imholz & J. L. A. Pennings & A. de Bruin & Á. Gyenis & J. Pothof & J. Vijg & H. van Steeg & J. H. J. Hoeijmakers - 432-432 Correction: Corrigendum: Convergence of terrestrial plant production across global climate gradients
by Sean T. Michaletz & Dongliang Cheng & Andrew J. Kerkhoff & Brian J. Enquist - 433-435 Reproducibility: Respect your cells!
by Monya Baker - 437-439 Industry: Open for business
by Chris Woolston - 439-439 Turning point: Activist engineer
by Virginia Gewin - 442-442 A perfect medium for unrequited love
by Alex Shvartsman
September 2016, Volume 537, Issue 7619
- 49-49 Precision medicine
by Richard Hodson - 52-53 Medical histories
by Amber Dance - 54-56 Technology: Read the instructions
by Andrew R. Scott - 57-59 Gene therapy: Industrial strength
by Eric Bender - 60-62 Pharmacogenetics: The right drug for you
by Liam Drew - 63-63 Perspective: The precision-oncology illusion
by Vinay Prasad - 64-65 Diagnosis: A clear answer
by Emily Sohn - 66-68 Participation: Power to the patients
by Katherine Bourzac - 69-69 Q&A: Kathy Hudson
by Eric Bender - 70-72 Privacy: The myth of anonymity
by Neil Savage - 139-139 The debate over GM crops is making history
by Vivian Moses - 145-146 Mars contamination fear could divert Curiosity rover
by Alexandra Witze - 147-147 London super-lab opens under cloud of Brexit
by Ewen Callaway - 148-148 Boom in unproven cell therapies intensifies regulatory debate
by Heidi Ledford - 149-149 US science agencies face budget limbo
by Sara Reardon - 149-150 Venerable brain-cancer cell line faces identity crisis
by Elie Dolgin - 152-155 How to raise a genius: lessons from a 45-year study of super-smart children
by Tom Clynes - 156-158 The new breed of cutting-edge catalysts
by XiaoZhi Lim - 159-161 Use antimicrobials wisely
by Peter S. Jørgensen & Didier Wernli & Scott P. Carroll & Robert R. Dunn & Stephan Harbarth & Simon A. Levin & Anthony D. So & Maja Schlüter & Ramanan Laxminarayan - 162-164 Science journals: The worlds of H. G. Wells
by Simon J. James - 165-166 Science fiction: Boldly going for 50 years
by Sidney Perkowitz - 167-167 Bite like a spider, sting like a scorpion
by Reza Afshari - 167-167 Antibiotic partners promote discovery
by Johan S. Bakken - 167-167 Report released on antibiotic resistance
by Jeremy Farrar & Sally Davies - 167-167 Brexit threatens China collaboration
by Hong Yang & Roger J. Flower & Xianjin Huang - 167-167 Gap widens for honorary PhDs
by Steven Watterson - 168-168 Ahmed Hassan Zewail (1946–2016)
by Warren S. Warren - 170-171 Designing the ideal opioid
by Brigitte L. Kieffer - 171-172 Slippery when narrow
by Angelos Michaelides - 172-173 Mapping the terrestrial human footprint
by Philip J. K. McGowan - 174-175 Violent emissions of newborn stars
by Markus Röllig - 175-176 Catalytic spliceosome captured
by Brian Kosmyna & Charles C. Query - 176-177 Fin to limb within our grasp
by Aditya Saxena & Kimberly L. Cooper - 179-184 Photocontrol of fluid slugs in liquid crystal polymer microactuators
by Jiu-an Lv & Yuyun Liu & Jia Wei & Erqiang Chen & Lang Qin & Yanlei Yu - 185-190 Structure-based discovery of opioid analgesics with reduced side effects
by Aashish Manglik & Henry Lin & Dipendra K. Aryal & John D. McCorvy & Daniela Dengler & Gregory Corder & Anat Levit & Ralf C. Kling & Viachaslau Bernat & Harald Hübner & Xi-Ping Huang & Maria F. Sassano & Patrick M. Giguère & Stefan Löber & Da Duan & Grégory Scherrer & Brian K. Kobilka & Peter Gmeiner & Bryan L. Roth & Brian K. Shoichet - 191-196 Structure of the voltage-gated calcium channel Cav1.1 at 3.6 Å resolution
by Jianping Wu & Zhen Yan & Zhangqiang Li & Xingyang Qian & Shan Lu & Mengqiu Dong & Qiang Zhou & Nieng Yan - 197-201 Cryo-EM structure of the spliceosome immediately after branching
by Wojciech P. Galej & Max E. Wilkinson & Sebastian M. Fica & Chris Oubridge & Andrew J. Newman & Kiyoshi Nagai - 202-206 Structural basis for the antifolding activity of a molecular chaperone
by Chengdong Huang & Paolo Rossi & Tomohide Saio & Charalampos G. Kalodimos - 207-209 Compression and ablation of the photo-irradiated molecular cloud the Orion Bar
by Javier R. Goicoechea & Jérôme Pety & Sara Cuadrado & José Cernicharo & Edwige Chapillon & Asunción Fuente & Maryvonne Gerin & Christine Joblin & Nuria Marcelino & Paolo Pilleri - 210-213 Massive radius-dependent flow slippage in carbon nanotubes
by Eleonora Secchi & Sophie Marbach & Antoine Niguès & Derek Stein & Alessandro Siria & Lydéric Bocquet - 214-219 Oxidative diversification of amino acids and peptides by small-molecule iron catalysis
by Thomas J. Osberger & Donald C. Rogness & Jeffrey T. Kohrt & Antonia F. Stepan & M. Christina White - 220-224 A progressively wetter climate in southern East Africa over the past 1.3 million years
by T. C. Johnson & J. P. Werne & E. T. Brown & A. Abbott & M. Berke & B. A. Steinman & J. Halbur & S. Contreras & S. Grosshuesch & A. Deino & C. A. Scholz & R. P. Lyons & S. Schouten & J. S. Sinninghe Damsté - 225-228 Digits and fin rays share common developmental histories
by Tetsuya Nakamura & Andrew R. Gehrke & Justin Lemberg & Julie Szymaszek & Neil H. Shubin - 229-233 Proteasome inhibition for treatment of leishmaniasis, Chagas disease and sleeping sickness
by Shilpi Khare & Advait S. Nagle & Agnes Biggart & Yin H. Lai & Fang Liang & Lauren C. Davis & S. Whitney Barnes & Casey J. N. Mathison & Elmarie Myburgh & Mu-Yun Gao & J. Robert Gillespie & Xianzhong Liu & Jocelyn L. Tan & Monique Stinson & Ianne C. Rivera & Jaime Ballard & Vince Yeh & Todd Groessl & Glenn Federe & Hazel X. Y. Koh & John D. Venable & Badry Bursulaya & Michael Shapiro & Pranab K. Mishra & Glen Spraggon & Ansgar Brock & Jeremy C. Mottram & Frederick S. Buckner & Srinivasa P. S. Rao & Ben G. Wen & John R. Walker & Tove Tuntland & Valentina Molteni & Richard J. Glynne & Frantisek Supek - 234-238 Germinal centre hypoxia and regulation of antibody qualities by a hypoxia response system
by Sung Hoon Cho & Ariel L. Raybuck & Kristy Stengel & Mei Wei & Thomas C. Beck & Emmanuel Volanakis & James W. Thomas & Scott Hiebert & Volker H. Haase & Mark R. Boothby - 239-243 The long non-coding RNA Morrbid regulates Bim and short-lived myeloid cell lifespan
by Jonathan J. Kotzin & Sean P. Spencer & Sam J. McCright & Dinesh B. Uthaya Kumar & Magalie A. Collet & Walter K. Mowel & Ellen N. Elliott & Asli Uyar & Michelle A. Makiya & Margaret C. Dunagin & Christian C. D. Harman & Anthony T. Virtue & Stella Zhu & Will Bailis & Judith Stein & Cynthia Hughes & Arjun Raj & E. John Wherry & Loyal A. Goff & Amy D. Klion & John L. Rinn & Adam Williams & Richard A. Flavell & Jorge Henao-Mejia - 244-248 PionX sites mark the X chromosome for dosage compensation
by Raffaella Villa & Tamas Schauer & Pawel Smialowski & Tobias Straub & Peter B. Becker - 249-253 Insights from biochemical reconstitution into the architecture of human kinetochores
by John R. Weir & Alex C. Faesen & Kerstin Klare & Arsen Petrovic & Federica Basilico & Josef Fischböck & Satyakrishna Pentakota & Jenny Keller & Marion E. Pesenti & Dongqing Pan & Doro Vogt & Sabine Wohlgemuth & Franz Herzog & Andrea Musacchio - 254-254 Correction: Corrigendum: sFRP2 in the aged microenvironment drives melanoma metastasis and therapy resistance
by Amanpreet Kaur & Marie R. Webster & Katie Marchbank & Reeti Behera & Abibatou Ndoye & Curtis H. Kugel & Vanessa M. Dang & Jessica Appleton & Michael P. O’Connell & Phil Cheng & Alexander A. Valiga & Rachel Morissette & Nazli B. McDonnell & Luigi Ferrucci & Andrew V. Kossenkov & Katrina Meeth & Hsin-Yao Tang & Xiangfan Yin & William H. Wood & Elin Lehrmann & Kevin G. Becker & Keith T. Flaherty & Dennie T. Frederick & Jennifer A. Wargo & Zachary A. Cooper & Michael T. Tetzlaff & Courtney Hudgens & Katherine M. Aird & Rugang Zhang & Xiaowei Xu & Qin Liu & Edmund Bartlett & Giorgos Karakousis & Zeynep Eroglu & Roger S. Lo & Matthew Chan & Alexander M. Menzies & Georgina V. Long & Douglas B. Johnson & Jeffrey Sosman & Bastian Schilling & Dirk Schadendorf & David W. Speicher & Marcus Bosenberg & Antoni Ribas & Ashani T. Weeraratna - 254-254 Correction: Corrigendum: Malaria: Thermoregulation in a parasite’s life cycle
by Jun Fang & Thomas F. McCutchan - 254-254 Correction: Corrigendum: Enhancer loops appear stable during development and are associated with paused polymerase
by Yad Ghavi-Helm & Felix A. Klein & Tibor Pakozdi & Lucia Ciglar & Daan Noordermeer & Wolfgang Huber & Eileen E. M. Furlong - 255-257 Lab life: Daydream and discover
by Emily Sohn - 257-257 Trade talk: Star selector
by Monya Baker - 259-270 Try catch throw
by Andrew Neil Gray
September 2016, Volume 537, Issue 7618
- 1-1 Science-led economies
by Herb Brody - 1-2 Verifying quantum superpositions at metre scales
by D. M. Stamper-Kurn & G. E. Marti & H. Müller - 2-3 Kovachy et al. reply
by T. Kovachy & P. Asenbaum & C. Overstreet & C. A. Donnelly & S. M. Dickerson & A. Sugarbaker & J. M. Hogan & M. A. Kasevich - 2-3 Big science spenders
by Alla Katsnelson - 4-5 Questioning Holocene community shifts
by Cleo Bertelsmeier & Sébastien Ollier - 4-5 Rwanda: From killing fields to technopolis
by Linda Nordling - 5-6 Lyons et al. reply
by S. Kathleen Lyons & Joshua H. Miller & Anikó Tóth & Kathryn L. Amatangelo & Anna K. Behrensmeyer & Antoine Bercovici & Jessica L. Blois & Matt Davis & William A. DiMichelle & Andrew Du & Jussi T. Eronen & J. Tyler Faith & Gary R. Graves & Nathan Jud & Conrad Labandeira & Cindy V. Looy & Brian McGill & David Patterson & Silvia Pineda-Munoz & Richard Potts & Brett Riddle & Rebecca Terry & Werner Ulrich & Amelia Villaseñor & Scott Wing & Heidi Anderson & John Anderson & Nicholas J. Gotelli - 6-7 The Middle East: An end to oil dependency
by Louise Sarant - 8-9 China: High-tech transformation
by Annabel McGilvray - 9-9 Preserve personal freedom in networked societies
by Christoph Bock - 10-11 Russia: A faltering recovery
by Olga Dobrovidova - 12-13 Germany: Equality or excellence
by Anja Krieger - 14-15 Australia: Balancing act
by Bianca Nogrady - 15-16 Italian scientists shocked by earthquake devastation
by Alison Abbott & Quirin Schiermeier - 16-17 Nuclear power plants prepare for old age
by Jeff Tollefson - 16-17 Singapore: The brain-gain game
by Annabel McGilvray - 18-19 Massachusetts: Mass effect
by Neil Savage - 19-20 Print your own 3D Lucy to work out how the famous hominin died
by Ewen Callaway - 20-20 Perspective: Fix the incentives
by Julia Lane - 20-21 Majority of mathematicians hail from just 24 scientific ‘families’
by Davide Castelvecchi - 22-24 How DNA could store all the world’s data
by Andy Extance - 26-28 Vipers, mambas and taipans: the escalating health crisis over snakebites
by Carrie Arnold - 29-30 Stop ignoring misconduct
by Donald S. Kornfeld & Sandra L. Titus - 32-33 In retrospect: A New System of Chemical Philosophy
by Philip Ball - 33-33 Books in brief
by Barbara Kiser - 34-34 Could Pokémon Go boost birding?
by Fabio de Oliveira Roque - 34-34 Stuck between a rock and a hard place
by Yingchao Hu & Liangjun Hu - 34-34 Rate oceans' capital to help achieve SDGs
by Yonglong Lu - 34-34 Hallmark labs with a replicability record
by Mattia Andreoletti - 34-34 Fallacy of perfection harms peer review
by James C. Zimring & Steven L. Spitalnik - 36-37 Attack on amyloid-β protein
by Eric M. Reiman