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Estimating Consumer Exposure to PFOS and PFOA

Author

Listed:
  • David Trudel
  • Lea Horowitz
  • Matthias Wormuth
  • Martin Scheringer
  • Ian T. Cousins
  • Konrad Hungerbühler

Abstract

Perfluorinated compounds have been used for more than 50 years as process aids, surfactants, and for surface protection. This study is a comprehensive assessment of consumer exposure to perfluorooctane sulfonate (PFOS) and perfluorooctanoic acid (PFOA) from a variety of environmental and product‐related sources. To identify relevant pathways leading to consumer exposure to PFOS and PFOA a scenario‐based approach has been applied. Scenarios represent realistic situations where age‐ and gender‐specific exposure occurs in the everyday life of consumers. We find that North American and European consumers are likely to experience ubiquitous and long‐term uptake doses of PFOS and PFOA in the range of 3 to 220 ng per kg body weight per day (ng/kgbw/day) and 1 to 130 ng/kgbw/day, respectively. The greatest portion of the chronic exposure to PFOS and PFOA is likely to result from the intake of contaminated foods, including drinking water. Consumer products cause a minor portion of the consumer exposure to PFOS and PFOA. Of these, it is mainly impregnation sprays, treated carpets in homes, and coated food contact materials that may lead to consumer exposure to PFOS and PFOA. Children tend to experience higher total uptake doses (on a body weight basis) than teenagers and adults because of higher relative uptake via food consumption and hand‐to‐mouth transfer of chemical from treated carpets and ingestion of dust. The uptake estimates based on scenarios are within the range of values derived from blood serum data by applying a one‐compartment pharmacokinetic model.

Suggested Citation

  • David Trudel & Lea Horowitz & Matthias Wormuth & Martin Scheringer & Ian T. Cousins & Konrad Hungerbühler, 2008. "Estimating Consumer Exposure to PFOS and PFOA," Risk Analysis, John Wiley & Sons, vol. 28(2), pages 251-269, April.
  • Handle: RePEc:wly:riskan:v:28:y:2008:i:2:p:251-269
    DOI: 10.1111/j.1539-6924.2008.01017.x
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    References listed on IDEAS

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    1. Matthias Wormuth & Martin Scheringer & Konrad Hungerbühler, 2005. "Linking the Use of Scented Consumer Products to Consumer Exposure to Polycyclic Musk Fragrances," Journal of Industrial Ecology, Yale University, vol. 9(1‐2), pages 237-258, January.
    2. Matthias Wormuth & Martin Scheringer & Meret Vollenweider & Konrad Hungerbühler, 2006. "What Are the Sources of Exposure to Eight Frequently Used Phthalic Acid Esters in Europeans?," Risk Analysis, John Wiley & Sons, vol. 26(3), pages 803-824, June.
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    3. Andrea B. Kirk & Kelsey Marie Plasse & Karli C. Kirk & Clyde F. Martin & Gamze Ozsoy, 2022. "Predicting Exposure to Perfluorinated Alkyl Substances (PFAS) among US Infants," IJERPH, MDPI, vol. 19(14), pages 1-16, July.
    4. Nilisha Khadgi Sonnenberg & Akinloye Emmanuel Ojewole & Catherine Oluwalopeye Ojewole & Otite Precious Lucky & Joseph Kusi, 2023. "Trends in Serum Per- and Polyfluoroalkyl Substance (PFAS) Concentrations in Teenagers and Adults, 1999–2018 NHANES," IJERPH, MDPI, vol. 20(21), pages 1-14, October.
    5. Natalie Von Goetz & Matthias Wormuth & Martin Scheringer & Konrad Hungerbühler, 2010. "Bisphenol A: How the Most Relevant Exposure Sources Contribute to Total Consumer Exposure," Risk Analysis, John Wiley & Sons, vol. 30(3), pages 473-487, March.
    6. Meng-Shan Tsai & Chihiro Miyashita & Atsuko Araki & Sachiko Itoh & Yu Ait Bamai & Houman Goudarzi & Emiko Okada & Ikuko Kashino & Hideyuki Matsuura & Reiko Kishi, 2018. "Determinants and Temporal Trends of Perfluoroalkyl Substances in Pregnant Women: The Hokkaido Study on Environment and Children’s Health," IJERPH, MDPI, vol. 15(5), pages 1-14, May.

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